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Tissue factor in predicted severe acute pancreatitis

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World Journal of Gastroenterology 2010年第48期16卷 6128-6134页

作者： ellen Andersson Jakob Axelsson Gunilla Eckerwall daniel Ansari Roland Andersson department of Surgery Clinical Sciences LundLund University Lund University Hospital

AIM: To study tissue factor (TF) in acute pancreatitis and evaluate the role of TF as a predictive marker of severity. METHOdS: Forty-nine consecutive patients admitted to Lund University Hospital, fulfilling the criteria of predicted severe acute pancreatitis (AP), were recruited prospectively between 2002 and 2004. Blood samples for TF analyses were drawn at inclusion in the study and 12 h, 1 d and 3 d later. RESULTS: Twenty-seven patients developed mild AP, and 22 patients severe AP. At inclusion in the study, the groups were comparable with respect to gender, aetiology, Acute Physiology and Chronic Health Evaluation Ⅱ score, and duration of pain. At inclusion in the study and at 12 h, TF was higher in the severe AP group (P = 0.035 and P = 0.049, respectively). After 1 and 3 d, no differences in TF levels were noted. Interleukin (IL)-6 was significantly higher in the severe AP group at all of the studied time points. C-reactive protein (CRP) was significantly higher in the AP group at 1 and 3 d. In receiver operating characteristic-curves, the area under the curve (AUC) for TF was 0.679 (P = 0.035) at inclusion in the study, and a cut off level for TF of 40 pg/mL showed a sensitivity of 71% and a specificity of 67%, whereas corresponding AUC for IL-6 was 0.775, P = 0.001, and for CRP was 0.653. IL-6 showed better AUC-values than TF at all time points studied. CONCLUSION: TF-levels are raised early in severe AP. TF as an early predictive marker of severe AP is superior to CRP, but inferior to IL-6.

关键词： Acute pancreatitis Coagulation Prediction of severity Tissue factor

Effects of connecting sequences of building blocks on reticular synthesis of covalent organic frameworks

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Nano Research 2021年第2期14卷 381-386页

作者： de-Li Ma Cheng Qian Qiao-Yan Qi zhong-Ri zhong Guo-Fang Jiang Xin Zhao State Key Lab of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan Universityf Changsha 410082China Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules Center for Excellence in Molecular SynthesisShanghai Institute of Organic ChemistryChinese Academy of Sciences345 Lingling RoadShanghai 200032China

The principle of reticular chemistry has been widely used to guide the design of crystalline porous materials such as metal organic frameworks(MOFs)and covalent organic frameworks(COFs).While in the early strategies only the symmetries of the building blocks were considered for reticular synthesis of COFs,recently a few researches on COFs with hierarchical porosities indicate that connecting sequence of building blocks also plays a crucial role in determining crystalline structures of ***,this important phenomenon has not been systematically investigated *** this article,a model system has been established to demonstrate how different connecting sequences of two C_(2v)-symmetric building blocks lead to the formation of four two-dimensional(2d)COFs with distinct framework *** verify this concept,target synthesis was conducted to produce three COFs,whose structures were confirmed by powder X-ray diffraction and pore size distribution analysis.

关键词： reticular chemistry covalent organic framework connecting sequence building block

Asymptotic Behaviour of Solutions to the Navier-stokes Equations of a Two-dimensional Compressible Flow

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Acta Mathematicae Applicatae Sinica 2011年第4期27卷 697-712页

作者： Ying-hui ZHANG zhong TAN department of Mathematics Hunan Institute of Science and Technology Yueyang 414006 China School of Mathematical Sciences Xiamen University Fujian 361005 China

In this paper, we are concerned with the asymptotic behaviour of a weak solution to the Navier-Stokes equations for compressible barotropic flow in two space dimensions with the pressure function satisfying p（g） = aglog^d（g） for large g. Here d 〉 2, a 〉 0. We introduce useful tools from the theory of Orlicz spaces and construct a suitable function which approximates the density for time going to infinity. Using properties of this function, we can prove the strong convergence of the density to its limit state. The behaviour of the velocity field and kinetic energy is also briefly discussed.

关键词： asymptotic behaviour Navier-stokes equations compressible barotropic flow Orlicz spaces

Effect of Zr-deoxidation on microstructure and mechanical behavior of microalloyed heavy plates with low impurity content

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Journal of Iron and Steel Research International 2021年第2期28卷 190-200页

作者： Cheng-yang Hu Hang-yu dong Kai-ming Wu R.d.K.Misra Lei zhong Xing Jin Qiang Li Laboratory for Excellence in Advanced Steel Research Materials Science and Engineering ProgramDepartment of MetallurgicalMaterials and Biomedical EngineeringUniversity of Texas at El PasoEl Paso 79968TXUSA The State Key Laboratory of Refractories and Metallurgy International Research Institute for Steel TechnologyCollaborative Innovation Center for Advanced SteelsWuhan University of Science and TechnologyWuhan 430081HubeiChina Research Institute of Nanjing Iron and Steel Co. Ltd.Nanjing 210035JiangsuChina

The significance of different deoxidation practises on the ductility and impact toughness of next generation of microalloyed heavy plates was elucidated to explore the best deoxidation practice in obtaining required mechanical properties,which was judged by the combined effects of composition,size and number density of inclusions on the ductility of the experimental high-strength low alloy *** impurity contents,i.e.,total O+N+S contents,of 82×10^(-6)(Al-killed)and 118×10^(-6)(Zr-killed)have been induced to characterize both the *** was characterized using tensile and Charpy V-notch *** number,size and composition of the inclusions were characterized using a field emission scanning electron microscope with an energy dispersive *** the Al-killed steel,the inclusion structure consisted of titanium nitrides,stringer calcium aluminates and elongated manganese sulfides,whereas in the Zr-killed steel,the inclusion structure consisted of mainly fine spherical oxide inclusions with sulphide *** impurity content did not have a significant effect on the number density of inclusions,as with higher and lower impurity content,the number of inclusions was 83.7 and 78.8 mm^(-2),***,the size distribution of the inclusions,especially the coarse inclusions with their longest length greater than 8μm,differsmuch from each *** number density of coarse inclusions differs from 0.8 to 1.1 mm^(-2) with processing,and in Al-killed steel,55.5% of the coarse inclusions were titanium nitrides or manganese sulfides,whereas in Zr-killed steel,only 22.5% of the coarse inclusions were titanium nitrides and manganese *** titanium nitrides were especially detrimental to the impact *** number density of them should be below 0.33 mm-2 in order to guarantee the best possible toughness in the steel in *** average crystallographic grain size detected by electron backscattered diffraction of Zr-killed steel(4

关键词： Microalloyed heavy plate Zr-killed technology Inclusion modification Mechanical property

Application of Computational Biology to decode Brain Transcriptomes

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Genomics, Proteomics & Bioinformatics 2019年第4期17卷 367-380页

作者： Jie Li Guang-zhong Wang CAS Key Laboratory of Computational Biology CAS-MPG Partner Institute for Computational BiologyShanghai Institute of Nutrition and HealthShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 200031China University of Chinese Academy of Sciences Beijing 100049China

The rapid development of high-throughput sequencing technologies has generated massive valuable brain transcriptome atlases,providing great opportunities for systematically investigating gene expression characteristics across various brain regions throughout a series of developmental *** studies have revealed that the transcriptional architecture is the key to interpreting the molecular mechanisms of brain ***,our knowledge of brain transcriptional characteristics remains very *** the immense efforts to generate high-quality brain transcriptome atlases,new computational approaches to analyze these highdimensional multivariate data are greatly *** this review,we summarize some public resources for brain transcriptome atlases and discuss the general computational pipelines that are commonly used in this field,which would aid in making new discoveries in brain development and disorders.

关键词： Brain transcriptome atlas Computational analysis Spatiotemporal pattern Coexpression analysis Single-cell analysis

One-dimensional ZnO Nanostructures： Solution Growth and Functional Properties

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Nano Research 2011年第11期4卷 1013-1098页

作者： Sheng Xu zhong Lin Wang School of Materials Science and Engineering Georgia Institute of Technology Atlanta Georgia 30332-0245 USA

One-dimensional （1d） ZnO nanostructures have been studied intensively and extensively over the last decade not only for their remarkable chemical and physical properties, but also for their diverse current and future technological applications. This article gives a comprehensive overview of the progress that has been made within the context of 1d ZnO nanostructures synthesized via wet chemical methods. We will cover the synthetic methodologies and the corresponding growth mechanisms, various nanostructures grown, their doping and alloying, and position-controlled growth on substrates. Finally, we will review their functional properties in catalysis, hydrophobic surface modification, sensing, and electronic, optical, optoelectronic, and energy harvesting devices.

关键词： ZnO one dimensional nanostructures solution growth electronic optical optoelectronic energy harvesting devices

Shape Optimization in Two-dimensional Viscous Compressible Fluids

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Acta Mathematica Sinica,English Series 2010年第9期26卷 1793-1806页

作者： zhong TAN Ying Hui ZHANG School of Mathematical Sciences Xiamen University Xiamen 361005 P. R. China department of Mathematics Hu'nan Institute of Science and Technology Yueyang 414006 P. R. China

We present a method for solving the optimal shape problems for profiles surrounded by viscous compressible fluids in two space dimensions. The class of admissible profiles is quite general including the minimal volume condition and a constraint on the thickness of the boundary. The fluid flow is modelled by the Navier-Stokes system for a general viscous barotropic fluid with the pressure satisfying p（o） = aQlog^d（o） for large Q. Here d 〉 1 and a 〉 0.

关键词： Optimization shape Orlicz spaces Navier-Stokes equations

Mutual eclipses of J2 Europa by J1 Io observed at Yunnan Observatory in 2009

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Research in Astronomy and Astrophysics 2011年第10期11卷 1243-1248页

作者： Xi-Liang Zhang zhong Liu National Astronomical Observatories/Yunnan Observatory Joint Laboratory for OpticalAstronomy Chinese Academy of Sciences Kunming 650011 China Graduate University of Chinese Academy of Sciences Beijing 100049 China

Mutual events between natural satellites include mutual occultation and mutual eclipse. Mutual eclipse is another kind of mutual occultation as viewed from the center of the Sun instead of the Earth. Two mutual eclipses of J2 Europa by J1 Io （2009 Aug. 28 and Sept. 12） were observed at Yunnan Observatory during the PHEMU09 international campaign. We will calculate the astrometric data of these Galilean satellites by analyzing and fitting the light curves we obtained. The limb-darkening was considered during modeling the light intensity of eclipsed satellites in the penumbra zone, by taking the Lommel-Seeliger scattering law into account. Several dynamical quantifies, such as the relative coordinates of the eclipsing satellite from the eclipsed one △α cos δ and △δ, impact parameter and mid-time corresponding to the impact parameter and the deviations O - C of observed △α cos d and △δ relative to ephemerides, were obtained for each event respectively.

关键词： eclipses -- kinematics and dynamics-methods -- planets and satellites individual: Galilean satellites

The double helium-white dwarf channel for the formation of AM CVn binaries

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Research in Astronomy and Astrophysics 2018年第1期18卷 101-112页

作者： Xian-Fei Zhang Jin-zhong Liu C.Simon Jeffery Philip d.Hall Shao-Lan Bi department of Astronomy Beijing Normal University Xinjiang Astronomical Observatory Chinese Academy of Sciences Armagh Observatory and Planetarium College Hill School of Physics Trinity College Dublin

Most close double helium white dwarfs will merge within a Hubble time due to orbital decay by gravitational wave ***,a significant fraction with low mass ratios will survive for a long time as a consequence of stable mass *** stable mass transfer between two helium white dwarfs（He Wds） provides one channel for the production of AM CVn binary *** previous calculations of double He Wd progenitors,the accreting He Wd was treated as a point *** have computed the evolution of 16 double He Wd models in order to investigate the consequences of treating the evolution of both components in *** find that the boundary between binaries having stable and unstable mass transfer is slightly modified by this *** comparing with observed periods and mass ratios,we redetermine masses of eight known AM CVn stars by our double He Wds channel,*** Cnc,AM CVn,V406 Hya,J0926,J1240,GP Com,Gaia14 aae and V396 *** propose that central spikes in the triple-peaked emission spectra of J1240,GP Com and V396 Hya and the surface abundance ratios of N/C/O in GP Com can be explained by the stable double He Wd *** mass estimates derived from our calculations are used to discuss the predicted gravitational wave signal in the context of the Laser Interferometer Space Antenna（LISA） project.

关键词： stars:peculiar(helium) stars:white dwarfs binaries:close gravitational waves