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Hospitalizations and in-hospital mortality for inflammatory bowel disease in Brazil

World Journal of Gastrointestinal Pharmacology and Therapeutics 2022年第1期13卷 1-10页

作者： Ana Luiza Vilar Guedes Amanda Lopes Lorentz Larissa fernandes de Almeida Rios Rios Beatriz Camara Freitas Adriano Gutemberg Neves Dias Ana Luísa Eckhard Uhlein Felipe Oliveira Vieira Neto Jobson Felipe soares Jesus Túlio de SáNovaes Torres Raquel Rocha Vitor D Andrade Genoile Oliveira Santana Life Sciences Department State University of BahiaSalvador 41150-000BahiaBrazil Sciences of Nutrition Federal University of BahiaSalvador 40110-060BahiaBrazil Medicine Department Universidade Salvador(UNIFACS)Salvador 41820-021BahiaBrazil Medicine and Health Postgraduate Program Federal University of BahiaSalvador 40110-060BahiaBrazil

BACKGROUND Inflammatory bowel disease(IBD)is associated with complications,frequent hospitalizations,surgery and *** introduction of biologic drugs into the therapeutic arsenal in the last two decades,combined with an expansion of immunosuppressant therapy,has changed IBD management and may have altered the profile of hospitalizations and in-hospital mortality(IHM)due to *** To describe hospitalizations from 2008 to 2018 and to analyze IHM from 1998 to 2017 for IBD in *** This observational,retrospective,ecological study used secondary data on hospitalizations for IBD in Brazil for 2008-2018 to describe hospitalizations and for 1998-2017 to analyze *** data were obtained from the Hospital Information System of the Brazilian Unified Health System and population data from demographic *** following variables were analyzed:Number of deaths and hospitalizations,length of hospital stay,financial costs of hospitalization,sex,age,ethnicity and type of hospital *** There was a reduction in the number of IBD hospitalizations,from 6975 admissions in 1998 to 4113 in 2017(trend:y=-0.1682x+342.8;R^(2)=0.8197;P<0.0001).The hospitalization rate also decreased,from 3.60/100000 in 2000 to 2.17 in *** rates varied during the 20-year period,between 2.06 in 2017 and 3.64 in 2007,and did not follow a linear trend(y=-0.0005049x+2.617;R^(2)=0,00006;P=0.9741).IHM rates also varied between regions,increasing in all but the southeast,which showed a decreasing trend(y=-0.1122x+4.427;R^(2)=0,728;P<0.0001).The Southeast region accounted for 44.29%of all *** Northeast region had the highest IHM rate(2.86 deaths/100 admissions),with an increasing trend(y=0.1105x+1.110;R^(2)=0.6265;P<0.0001),but the lowest hospitalization rate(1.15).The Midwest and South regions had the highest hospitalization rates(3.27 and 3.17,respectively).A higher IHM rate was observed for nonelective admissions(2.88),which accounted for 81%of IB

关键词： Inflammatory bowel disease Crohn’s disease Ulcerative colitis Hospitalization Hospital mortality Hospital information systems Epidemiology

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Risk Factors for Cervical Cancer in a Sample Comprising Three Generations of Brazilian Women

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Journal of Cancer Therapy 2017年第1期8卷 12-25页

作者： Ilce Ferreira da Silva Rosalina Jorge Koifman Virgilio Augusto Gomes Parreira Simone soares Sergio Koifman Instituto fernandes Figueira Fundacao Oswaldo Cruz Rio de Janeiro Brazil Escola Nacional de Saúde Pública Fundacao Oswaldo Cruz Rio de Janeiro Brazil Hospital do Cancer-II Instituto Nacional do Cancer Rio de Janeiro Brazil

Background: Cervical cancer is the main cause of cancer deaths in some developing countries. Age-related cervical cancer incidence has been fundamental for understanding the different stages of carcinogenesis concepts. No Brazilian study explored the environmental risk factors involved on cervical cancer, according to age groups taking 70’s sexual revolution in Brazil as reference. Aim: To determine the prevalence of epidemiological and clinical aspects related to cervical cancer development in a sample of three age groups of Brazilian women based on 70’s sexual revolution. Methods: A cross-section study was proceeded in a hospital-based cohort of women with altered Pap-test refereed to the National Cancer Institute for Colposcopy and treatment from October 2004 to May 2006. Two register nurses interviewed all patients ascertaining risk factors and clinical characteristics. Biopsy, partial ablation were used for CIN-1, and conization was the treatment for CIN-2/3. Results: From 318 women included in the study, 42.8% were 18 - 30 years old (born after 1975), 43.4% were 31 - 49 years old (born 1955-1975), and 13.8% were 50 - 68 years old (born 1936-1954). Pregnancies (OR = 1.16;CI95%: 1.01 - 1.34) and menarche under 12 years old (OR = 1.95;CI95%: 1.17 - 3.25) were independently associated to CIN2- 3/cancer in 18 - 30 age group;menopause age (OR = 1.21;CI95%: 1.04 - 1.41) and current smoking habit (OR = 1.37;CI95%: 1.10 - 1.70) were associated to CIN2- 3/cancer in 31 - 49 age group;no statistical significance was observed for 50 - 68 age group. Conclusion: Brazilian women present distinct risk for cervical cancer according to the generation they belong, when taking the Brazilian sexual revolution on 70’s as a reference.

关键词： Cervical Cancer Cross-Section Study Epidemiology Sexual Revolution Brazil

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Variables Associated with Cirrhosis Diagnosis in Patients with Chronic Hepatitis C: A Case-Control Study

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Health 2015年第12期7卷 1634-1641页

作者： Gilmar Amorim de Sousa Iris do Céu Clara Costa Dyego Leandro Bezerra de Souza Fabia Barbosa de Andrade Lívia Medeiros soares Celani Ranna Santos Pessoa Marlon César de Souza Filho Daniel fernandes Mello de Oliveira Luana Lopes de Medeiros Lucila Samara Dantas de Oliveira Maria Flávia Monteiro The Integrated Department of Medicine Federal University of Rio Grande do Norte UFRN Natal Brazil The Post-Graduate Program in Collective Health of UFRN Natal Brazil Gastroenterology Program of the University Hospital Onofre Lopes/UFRN Natal Brazil The Medical School of UFRN Natal Brazil

The diagnosis of liver cirrhosis in patients with chronic hepatitis C has not always been easy, since the gold standard method is the liver biopsy, which is an invasive procedure with interobserver accuracy problems and there have been reports of complications including records of deaths due to hemoperitoneum. Cirrhosis changes the prognosis of the subject with hepatitis C and requires a different clinical management. This study aimed to identify clinical and laboratory variables associated with the diagnosis of cirrhosis in the ultrasonography of patients infected with hepatitis C. In a case-control study, we evaluated 70 cirrhotic patients with chronic hepatitis C compared to a control group of 70 non-cirrhotic people with positive HCV. The results showed, through logistic regression analysis, that the variables blood donor and professional athlete, adjusted for alcohol consumption, showed OR 0.24 and 0.18, with p values of 0.044 and 0.035, respectively. We conclude that the diagnosis of cirrhosis in patients with chronic hepatitis C remains challenging, but the patients with the condition of blood donor or professional athlete prove to be less likely to cirrhosis in ultrasonography in the initial consultation.

关键词： Cirrhosis Biomakers Fibrosis Hepatitis C Virus Clinical Diagnosis Biopsy Non-Invasive Methods Scores Ultrasonography

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Retrospective Epidemiological Analysis of Colles’ Fracture in Patients Admitted in fernandes Távora Hospital

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Open Journal of Epidemiology 2023年第1期13卷 16-23页

作者： Yuri Borges Morais Antonio Valterno Nogueira Pinheiro Antonio Valterno Nogueira Pinheiro Filho Liana Alves de Freitas soares Borges Maria Suelly Nogueira Pinheiro Rian Vilar Lima Letícia Pinheiro Pontes Lia Camurça Costa Igor Castelo Branco Fontenele Costa Velko Veras Pereira de Matos Filho Professor da Faculdade de Medicina Centro Universitário Christus UNICHRISTUS Fortaleza Brasil Instituto Superior de Ciências Biomédicas—ISCB Universidade Estadual do Ceará UECE Fortaleza Brasil Departamento de Cirurgia Hospital Fernandes Távora HFT Fortaleza Brasil Faculdade de Medicina Universidade de Fortaleza UNIFOR Fortaleza Brasil Faculdade de Medicina Centro Universitário Christus UNICHRISTUS Fortaleza Brasil Faculdade de Medicina Universidade Federal do Ceará UFC Fortaleza Brasi

Background: Colles’ fracture is a type of fracture of the distal third of the radius and its most common cause is falling from patient’s own height and, epidemiologically, it is more common in the elderly. Objectives: The main objective of this study is to analyze the epidemiology of Colles’ fracture retrospectively, in patients admitted to fernandes Távora Hospital. Materials and Methods: This retrospective study conducted at the fernandes Távora Hospital used 1030 radiographic images of patients with wrist fractures. Results: (After a careful analysis) It was found that this type of fracture occurred with a greater frequency in age groups of 50 to 69, 60 to 69, and 40 to 49 years old, which corresponds to 59.5% of patients and the most affected sex were females (51.1%). Conclusion: The study concluded that this type of bone injury is more common in people aged 40 to 69 years old, especially in women, because of their geometry and bone composition. It is evident that Colles’ fracture impacts the life of the affected person, therefore, an adequate diagnosis and treatment having utmost importance.

关键词： Fracture Colles’ Fracture Epidemiology

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