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Space Tourism Moves Closer to Lift Off

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Engineering 2019年第5期5卷 819-821页

作者： elizabeth K.wilson 不详

Astronauts are not the only ones who dream of going into *** the earliest days of human spaceflight,many other people have also longed to view Earth and the heavens from above the atmosphere.

关键词： dream space. earliest

Wearable Sweat Sensors

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Engineering 2019年第3期5卷 359-360页

作者： elizabeth K. wilson Senior Technology Writer

Sweat, like blood, contains electrolytes and biomolecules that can reveal aspects of a person’s physiology, from hydration to kidney function. Though scientists have long recognized sweat’s potential use as a medica... 详细信息

关键词： Wearable Sweat Sensors

A Smart Pill for Insulin?

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Engineering 2019年第4期5卷 603-604页

作者： elizabeth K.wilson 不详

Diabetes remains a substantial—and growing—public health problem,afflicting almost 10%of the US population(30 million people)and a similar percentage in China(10 million),with the latter number expected to increase to 150 million by 2040[1,2].Meanwhile,the basic treatment for diabetes has also largely remained unchanged,with most patients still facing the daunting ordeal of regular daily injections of *** of the significant burden this represents,and the clinical benefits that might be achieved with a more patient-friendly solution,finding a noninjectable alternative to deliver insulin has long been a holy grail for drug developers.

关键词： unchanged latter finding

Nucleation of Supercooled Water by Neutrons: Latitude Dependence and Implications for Cloud Modelling

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Atmospheric and Climate Sciences 2024年第2期14卷 221-232页

作者： Peter W. wilson elizabeth wilson-Park Abraham G. wilson Department of Physics The University at Albany SUNY Albany USA Scripps Institution of Oceanography University of California San Diego USA Philanthropy Australia Sydney Australia The King’ s Institute The King&#8217s School Parramatta Australia

It has recently been shown that incident particles, neutrons, can initiate the freezing in a supercooled water volume. This new finding may have ramifications for the interpretation of both experimental data on the nucleation of laboratory samples of supercooled water and perhaps more importantly on the interpretation of ice nucleation involved in cloud physics. For example, if some fraction of the cloud nucleation previously attributed to dust, soot, or aerosols has been caused by cosmogenic neutrons, fresh consideration is required in the context of climate models. Moreover, as cosmogenic neutrons, most being muon-induced, have much greater flux at high latitudes, estimates of ice nucleates in these regions may be larger than required to accurately model cloud and condensation properties. This discrepancy has been pointed out in IPCC reports. Our paper discusses the connection between the new concept of neutrons nucleating supercooled water and the need for a new source of nucleation in high latitude clouds, ideally causing others to review current data, or to analyse future data with this idea in mind. .

关键词： Climate Models Ice Nucleation Neutrons Supercooling

Multicentre collaborative cohort study of the use of Kirschner wires for the management of supracondylar fractures in children

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Chinese Journal of Traumatology 2019年第5期22卷 249-254页

作者： Henry Claireaux Richard Goodall Joshua Hill elizabeth wilson Philippa Coull Sebastian Green James Schuster-Bruce Diana Lim Joanna Miles Payam Tarassoli University of Bristol Senate HouseTyndall AveBristolBS8 1THUK Bristol Royal Hospital for Children Maudlin StBristolBS2 8BJUK

Purpose:Supracondylar fractures of the humerus cause significant morbidity in *** damage and loss of fracture reduction are common recognised complications in patients with this *** surrounds the optimal Kirschner wire configuration and diameter for closed reduction and pinning of these *** study describes current practice and examined the association between wire configuration or diameter and outcomes(clinical and radiological)in the operative management of paediatric supracondylar ***:Children presenting w让h GartlandⅡorⅢsupracondylar fractures at five hospitals in southwest England were eligible for *** scrutinised paper and electronic case *** measures were maintenance of reduction and iatrogenic nerve ***:Altogether 209 patients were eligible for inclusion:15.7%had a documented neurological deficit at presentation;3.9%who were neurologically intact at presentation sustained a new deficit caused by treatment and 13.4%experienced a clinically significant loss of reduction following *** of reduction was significantly better in patients treated specifically with crossed×3 Kirschner wire configuration compared to all other *** incidence of iatrogenic nerve injury was not significantly different between groups treated with different wire ***:We present a large multicentre cohort study showing that crossed×3 Kirschner wires are associated with better maintenance of reduction than crossed×2 or lateral entry *** numbers would be required to properly investigate nerve injury relating to operative management of supracondylar *** found significant variations in practice and compliance w让h the British Orthopaedic Association Standard for Trauma(BOAST)11 guidelines.

关键词： Fracture fixation Humerus Child Nerve injury Bone wires

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梦想的装扮

Semantic Segmentation of Lumbar Vertebrae Using Meijering U-Net(MU-Net)on Spine Magnetic Resonance Images

作者： (英)伊丽莎白·威尔逊(elizabeth wilson)

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 733-757页

作者： Lakshmi S V V Shiloah elizabeth Darmanayagam Sunil Retmin Raj Cyril Department of Computer Science and Engineering College of Engineering GuindyAnna UniversityChennai600025India Department of Information Technology Madras Institute of TechnologyAnna UniversityChrompetChennai600044India

Lower back pain is one of the most common medical problems in the world and it is experienced by a huge percentage of people *** to its ability to produce a detailed view of the soft tissues,including the spinal cord,nerves,intervertebral discs,and vertebrae,Magnetic Resonance Imaging is thought to be the most effective method for imaging the *** semantic segmentation of vertebrae plays a major role in the diagnostic process of lumbar *** is difficult to semantically partition the vertebrae in Magnetic Resonance Images from the surrounding variety of tissues,including muscles,ligaments,and intervertebral discs.U-Net is a powerful deep-learning architecture to handle the challenges of medical image analysis tasks and achieves high segmentation *** work proposes a modified U-Net architecture namely MU-Net,consisting of the Meijering convolutional layer that incorporates the Meijering filter to perform the semantic segmentation of lumbar vertebrae L1 to L5 and sacral vertebra ***-colour mask images were generated and used as ground truth for training the *** work has been carried out on 1312 images expanded from T1-weighted mid-sagittal MRI images of 515 patients in the Lumbar Spine MRI Dataset publicly available from Mendeley *** proposed MU-Net model for the semantic segmentation of the lumbar vertebrae gives better performance with 98.79%of pixel accuracy(PA),98.66%of dice similarity coefficient(DSC),97.36%of Jaccard coefficient,and 92.55%mean Intersection over Union(mean IoU)metrics using the mentioned dataset.

关键词： Computer aided diagnosis(CAD) magnetic resonance imaging(MRI) semantic segmentation lumbar vertebrae deep learning U-Net model

先天性心脏病患儿肝素效应与凝血酶抑制因子水平的临床检测

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麻醉与镇痛 2008年第2期4卷 23-30页

作者： Nina A. Guzzetta Bruce E. Miller Kathy Todd Fania Szlam, MMSc Renee H. Moore Keith K. Brosius elizabeth C. wilson Anna M. Cohen Steven R. Tosone 陈蕾(译) 徐美英(校) Department of Anesthesiology Emory University School of Medicine Cardiac Research Department Children's Healthcare of Atlanta at Egleston Department of Biostatistics Emory University Atlanta Georgia 不详

本研究观察了体外循环（CPB）下行心脏手术的先天性心脏病患儿3种凝血酶抑制因子[抗凝血酶Ⅲ（ATⅢ）、肝素辅助因子Ⅱ（HCⅡ）、α-2-巨球蛋白（α2M）]水平与临床不同检测肝素效应方法间的关系。118例患儿分为6个年龄组：〈1个月龄．1... 详细信息

本研究观察了体外循环（CPB）下行心脏手术的先天性心脏病患儿3种凝血酶抑制因子[抗凝血酶Ⅲ（ATⅢ）、肝素辅助因子Ⅱ（HCⅡ）、α-2-巨球蛋白（α2M）]水平与临床不同检测肝素效应方法间的关系。118例患儿分为6个年龄组：〈1个月龄．1～3个月龄，3—6个月龄，6～12个月龄，12～24个月龄，〉10岁。测定基础ATⅢ、HCⅡ、α2M数值。同时测定白陶土法活化凝血时间（k-ACT）、硅藻土法活化凝血时间（c-ACT）的基础值并在应用标准剂量400U／kg肝素3分钟后再次测定k-ACT和c-ACT。计算每例患儿应用肝素前、后ACT的差值和肝素量-效关系。给予肝素后k-ACT较c-ACT的变异性小。与既往在成人中证实的结果不同，ATⅢ以及其他凝血酶抑制因子与肝素效应的临床检测间无正性相关；而且〈1个月龄组患儿不仅ATⅢ、HCⅡ水平低．α2M水平也较低。研究结果对肝素是否能在新生儿体外循环手术中发挥充分的抗凝效应提出了疑义，并对ACT延长作为反映抗凝程度的精确性提出了挑战。

关键词：肝素辅助因子Ⅱ 抗凝血酶Ⅲ 先天性心脏病临床检测抑制因子患儿活化凝血时间水

Protocoled thrombolytic therapy for frostbite improves phalangeal salvage rates

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Burns & Trauma 2020年第1期8卷 338-346页

作者： Rosemary elizabeth Paine elizabeth Noel Turner Daniel Kloda Carolyne Falank Bruce Chung Damien wilson Carter Department of Surgery Maine Medical Center22 Bramhall StPortlandMaine 04102USA Department of Radiology Maine Medical Center22 Bramhall StPortlandMaine 04102USA

Background:Frostbite is a cold injury that has the potential to cause considerable morbidity and long-term *** the complexity of these patients,diagnostic and treatment practices lack *** therapy has emerged as a promising treatment modality,demonstrating impressive digit salvage *** review our experience with thrombolytic therapy for severe upper extremity ***:Retrospective data on all frostbite patients evaluated at our institution from December 2017 to March 2018 was collected.A subgroup of patients with severe frostbite treated with intraarterial thrombolytic therapy(IATT)were ***:Of the 17 frostbite patients treated at our institution,14(82%)were male and the median age was 31(range:19–73).Substance misuse was involved in a majority of the cases(58.8%).Five(29.4%)patients with severe frostbite met inclusion criteria for IATT and the remaining patients were treated *** demonstrated a 74.5%improvement in perfusion after tissue plasminogen activator *** comparing phalanges at risk on initial angiography to phalanges undergoing amputation,the phalangeal salvage rate was 83.3%and the digit salvage rate was 80%.Complications associated with IATT included groin hematoma,pseudoaneurysm and retroperitoneal ***:Thrombolytic therapy has the potential to greatly improve limb salvage and functional recovery after severe frostbite when treated at an institution that can offer comprehensive,protocoled thrombolytic therapy.A multi-center prospective study is warranted to elucidate the optimal treatment strategy in severe frostbite.

关键词： Frostbite Tissue plasminogen activator Amputation Digit salvage Thrombolysis