BACKGROUND Anastomotic leaks(AL)and gastric conduit necrosis(CN)are serious complications following *** studies have suggested that vascular calcification may be associated with an increased AL rate,but this has not b...
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BACKGROUND Anastomotic leaks(AL)and gastric conduit necrosis(CN)are serious complications following *** studies have suggested that vascular calcification may be associated with an increased AL rate,but this has not been validated in a United Kingdom *** To investigate whether vascular calcification identified on the pre-operative computed tomography(CT)scan is predictive of AL or *** Routine pre-operative CT scans of 414 patients who underwent oesophagectomy for malignancy with oesophagogastric anastomosis at the Queen elizabeth Hospital Birmingham between 2006 and 2018 were retrospectively *** of the proximal aorta,distal aorta,coeliac trunk and branches of the coeliac trunk was scored by two *** relationship between these calcification scores and occurrence of AL and CN was then *** Esophagectomy Complications Consensus Group definition of AL and CN was *** Complication data were available in n=411 patients,of whom 16.7%developed either AL(15.8%)or CN(3.4%).Rates of AL were significantly higher in female patients,at 23.0%,compared to 13.9%in males(P=0.047).CN was significantly more common in females,(8.0%vs 2.2%,P=0.014),patients with diabetes(10.6%vs 2.5%,P=0.014),a history of smoking(10.3%vs 2.3%,P=0.008),and a higher American Society of Anaesthesiologists grade(P=0.024).Out of the 14 conduit necroses,only 4 occurred without a concomitant *** statistically significant association was found between calcification of any of the vessels studied and either of these *** analyses were then performed to identify whether a combination of the calcification scores could be identified that would be significantly predictive of any of the ***,the stepwise approach did not select any factors for inclusion in the final *** analysis was repeated for composite outcomes of those patients with either AL or CN(n=69,16.7%)and for those with both AL and CN(n=10,2.
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