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Ca-based materials derived from calcined cigarette butts for CO_(2)capture and thermochemical energy storage

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Journal of Environmental Sciences 2024年第6期140卷 230-241页

作者： Nabil Amghar Virginia Moreno pedro E.Sánchez-Jiménez Antonio perejón Luis A.pérez-Maqueda Instituto de Ciencia de Materiales de Sevilla C.S.I.C.-Universidad de SevillaC.Américo Vespucio4941092 SevillaSpain Instituto de Tecnología de Materiales(ITM) Universitat Politècnica de València(UPV)Plaza Ferrándiz y Carbonell 1AlcoyAlicante 03801Spain Departamento de Química Inorgánica Facultad de QuímicaUniversidad de Sevilla41012 SevillaSpain

Cigarette butts(CBs)are one of the most common types of litter in the *** to the toxic substances they contain,the waste generated poses a harmful risk to the environment,and therefore there is an urgent need for alternative solutions to landfill ***,this work presents a possible revalorization of this waste material,which implies interesting environmental *** were used as sacrificial templates for the preparation of CaO-based materials by impregnation with calcium and magnesium nitrates followed by flaming *** materials presented enhanced porosity for their use in the Calcium Looping process applied either to thermochemical energy storage or CO_(2)capture *** influence of the concentration of Ca and Mg in the impregnating solutions on the multicycle reactivity of the samples was *** improved multicycle performance was obtained in terms of conversion for both applications.

关键词： Cigarette butts Calcium-Looping CO_(2)Capture Thermochemical energy storage

Do endemic species always have a low competitive ability? A test for two Mediterranean plant species under controlled conditions

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Journal of plant Ecology 2012年第3期5卷 305-312页

作者： Eric Imbert Sami Youssef David carbonell Alex Baumel Institut des Sciences de l’Evolution CNRS 5554Universite Montpellier 2France Institut Mediterraneen d’Ecologie et de paleoecologie UMR CNRS/IRD 6116Universite Aix MarseilleFrance

Aims Many observations concerning biological and ecological differentiation between narrow endemic and widespread congeneric plant species suggest that narrow endemic species are constrained to colonize marginal habitats because of a low tolerance to *** this topic being an important issue both for understanding evolutionary processes leading to endemism and for conservation purposes,few studies have been performed to compare competitive abilities between endemic and widespread ***,we present two independent experiments performed under controlled conditions using two different pairs of endemic and widespread congeneric species:Centaurea corymbosa/Centaurea maculosa and Arenaria provincialis/Arenaria serpyllifolia,both endemic species occurring in rocky calcareous *** Mature seeds of *** and *** were sown in pots containing ramets of the common grass,Brachypodium *** were sorted in three treatments according to grass cover(low,intermediate and high).A control treatment(without competition)was also ***,seedling survival and rosette growth were *** the comparisons between *** and ***,seeds from natural populations were first sown without a *** week after germination,healthy seedlings were transplanted in pots without Brachypodium seedling(control)or containing two Brachypodium seedlings(low competition)or four seedlings(high competition).We checked the number of capsules per individual,and we harvested the biomass after capsule *** Findings Despite differences in the protocol design,results are congruent,and in both cases,endemic species are highly affected by the presence of a competitor,as are the widespread species,although we did not detect any differences between species for response to *** results are discussed in relation to processes leading to endemism,suggesting that the specialist model is more likely for both the

关键词： endemism conservation biology Mediterranean area competitive response

Ubiquitin-proteasome system and oxidative stress in liver transplantation

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World Journal of Gastroenterology 2018年第31期24卷 3521-3530页

作者： Norma Alva Arnau panisello-Roselló Marta Flores Joan Roselló-Catafau Teresa carbonell Department of Cell Biology Physiology and ImmunologyUniversity of Barcelona Experimental pathology Department Institute of Biomedical Research of Barcelona

A major issue in organ transplantation is the development of a protocol that can preserve organs under optimal conditions. Damage to organs is commonly a consequence of flow deprivation and oxygen starvation following the restoration of blood flow and reoxygenation. This is known as ischemia-reperfusion injury(IRI): a complex multifactorial process that causes cell damage. While the oxygen deprivation due to ischemia depletes cell energy, subsequent tissue oxygenation due to reperfusion induces many cascades, from reactive oxygen species production to apoptosis initiation. Autophagy has also been identified in the pathogenesis of IRI, although such alterations and their subsequent functional significance are controversial. Moreover, proteasome activation may be a relevant pathophysiological mechanism. Different strategies have been adopted to limit IRI damage, including the supplementation of commercial preservation media with pharmacological agents or additives. In this review, we focus on novel strategies related to the ubiquitin proteasome system and oxidative stress inhibition, which have been used to minimize damage in liver transplantation.

关键词： Liver transplant Ischemia-reperfusion injury Oxidative stress proteasome Redox regulation Ubiquitin

Geotechnical particle finite element method for modeling of soilstructure interaction under large deformation conditions

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Journal of Rock Mechanics and Geotechnical Engineering 2022年第3期14卷 967-983页

作者： Josep Maria carbonell Lluís Monforte Matteo O.Ciantia Marcos Arroyo Antonio Gens MECAMAT Group Department of EngineeringFaculty of Science and TechnologyUniversitat de Vic-Universitat Central de Catalunya(UVic-UCC)VicSpain Centre Internacional de Mètodes Numèrics a l'Enginyeria(CIMNE) BarcelonaSpain School of Science and Engineering University of DundeeDundeeUK Universitat politècnica de Cataluna-BarcelonaTech BarcelonaSpain

The possibilities of the particle finite element method(pFEM)for modeling geotechnical problems are increasingly *** is a numerical approach to solve large displacement and large strain continuum problems that are beyond the capabilities of classical finite element method(FEM).In pFEM,the computational domain is reconfigured for optimal solution by frequent remeshing and boundary *** inherits many concepts,such as a Lagrangian description of continuum,from classic geomechanical *** familiarity with more popular numerical methods facilitates learning and *** work focuses on G-pFEM,a code specifically developed for the use of pFEM in geotechnical *** article has two *** first is to give the reader an overview of the capabilities and main features of the current version of the G-pFEM and the second is to illustrate some of the newer developments of the code.G-pFEM can solve coupled hydro-mechanical static and dynamic problems involving the interaction of solid and/or deformable *** constitutive models for geomaterials are available,including features,such as structure and destructuration,which result in brittle *** solutions are robust,solidly underpinned by numerical technology including mixedfield formulations,robust and mesh-independent integration of elastoplastic constitutive models and a rigorous and flexible treatment of contact *** novel features presented in this work include the contact domain technique,a natural way to capture contact interactions and impose contact constraints between different continuum bodies,as well as a new simplified formulation for dynamic impact *** code performance is showcased by the simulation of several soil-structure interaction problems selected to highlight the novel code features:a rigid footing insertion in soft rock,pipeline insertion and subsequent lateral displacement on over-consolidated clay,screw-pile pull-out and the dyn

关键词： particle finite element method(pFEM) Structured soils Nonlocal elastoplasticity Contact domain method Soil penetration problems

A comprehensive study of the proteins involved in salinity stress response in roots and shoots of the FL478 genotype of rice(Oryza sativa L. ssp. indica)

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The Crop Journal 2021年第5期9卷 1154-1168页

作者： Camilo Lopez-Cristoffanini Mireia Bundo Xavier Serrat Blanca San Segundo Marta Lopez-carbonell Salvador Nogues Departament de Biologia Evolutiva Ecologia i Ciències AmbientalsSeccio de Fisiologia VegetalUniversitat de Barcelona08028 BarcelonaSpain Centre for Research in Agricultural Genomics(CRAG) CSIC-IRTA-UAB-UBEdifici CRAGCampus de la UAB08193 BellaterraBarcelonaSpain Consejo Superior de Investigaciones Científicas(CSIC) BarcelonaSpain

Rice,a major staple,is the most salt-sensitive *** salinity triggers several adaptive responses in rice to cope with osmotic and ionic stress at the physiological,cellular,and molecular levels.A major QTL for salinity tolerance,named Saltol,is present on chromosome 1 of Indian landraces such as pokkali and Nona *** early proteomic and physiological responses to salinity in roots and shoots of FL478,an inbred rice line harboring the Saltol QTL,were *** were cultured in hydroponic cultures with 100 mmol L^(-1) Na Cl and evaluated at 6,24,and 48 *** the physiological level,root length significantly increased at 48 h,whereas shoot length was *** Na^(+)/K^(+) ratio was maintained at lower levels in shoots than in roots,suggesting that roots play a protective *** than 2000 proteins were detected in both *** showed a faster and more coordinated proteomic response than shoots,evident after only 6 h of *** responses showed clear correspondence with those of proteins involved in transcription and *** of mitochondrial activity and amino acid metabolism in roots,and activation of stress-responsive proteins such as dehydrins and pLAT in shoots,may play a key role during the response of the plant to salinity *** and physiological responses showed that roots respond in a more highly adaptive manner than shoots to salinity stress,suggesting that this tissue is critical to the tolerance observed in cultivars harboring Saltol.

关键词： FL478 Shotgun proteomics Rice Salinity Root Saltol

Management of post-operative complications in open ventral hernia repair

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plastic and Aesthetic Research 2019年第11期6卷 32-40页

作者： Sean C.O'Connor Alfredo M.carbonell Department of Surgery Prisma Health-UpstateUniversity of South Carolina School of Medicine-GreenvilleGreenvilleSC 29605USA

Hernia repair is the most common general surgical procedure performed in the United States;however,historically,there has been a surprising lack of consensus regarding hernia complications and their *** development of international,prospectively-collected databases such as the Americas Hernia Society Quality Collaborative has introduced a new era of evidence-based practice around the prevention and management of these *** review seeks to equip surgeons with evidence-based techniques for prevention and management of the most common complications of open ventral hernia repair.

关键词： Hernia repair complications surgical site infection seroma flap necrosis mesh exposure interparietal hernia recurrent hernia enterocutaneous fistula

Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells

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World Journal of Gastroenterology 2006年第36期12卷 5834-5845页

作者： Raquel Taléns-Visconti Ana Bonora Ramiro Jover Vicente Mirabet Francisco carbonell José Vicente Castell María José Gómez-Lechón Unidad de Hepatología Experimental Centro de Investigación Hospital La Fe Valencia Spain Departamento de Bioquímica y Biología Molecular Universidad de Valencia Valencia Spain. Unidad de Hepatología Experimental Centro de Investigación Hospital La Fe Valencia Spain Centro de Transfusión de la Comunidad Valenciana Generalidad ValencianaValencia Spain Unidad de Hepatología Experimental Centro de Investigación Hospital La Fe Valencia.Spain. Departamento de Bioquímica y Biología Molecular Universidad de Valencia Valencia Spain Unidad de Hepatología Experi-mental Centro de Investigación Hospital La Fe Valencia Spain

AIM： To investigate and compare the hepatogenic transdifferentiation of adipose tissue-derived stem cells （ADSC） and bone marrow-derived mesenchymal stem cells （BMSC） in vitro. Transdifferentiation of BMSC into hepatic cells in vivo has been described. Adipose tissue represents an accessible source of ADSC, with similar characteristics to BMSC. METHODS： BMSCs were obtained from patients undergoing total hip arthroplasty and ADSC from human adipose tissue obtained from lipectomy. Cells were grown in medium containing 15% human serum. Cultures were serum deprived for 2 d before cultivating under similar pro-hepatogenic conditions to those of liver development using a 2-step protocol with sequential addition of growth factors, cytokines and hormones. Hepatic differentiation was RT-pCR-assessed and liver-marker genes were immunohistochemically ***： BMSC and ADSC exhibited a fibroblastic morphology that changed to a polygonal shape when cells differentiated. Expression of stem cell marker Thyl decreased in differentiated ADSC and BMSC. However, the expression of the hepatic markers, albumin and CYps increased to a similar extent in differentiated BMSC and ADSC. Hepatic gene activation could be attributed to increased liver-enriched transcription factors （C/EBpβ and HNF4α）, as demonstrated by adenoviral expression ***： Mesenchymal stem cells can be induced to hepatogenic transdifferentiation in vitro. ADSCs have a similar hepatogenic differentiation potential to BMSC, but a longer culture period and higher proliferation capacity. Therefore, adipose tissue may be an ideal source of large amounts of autologous stem cells, and may become an alternative for hepatocyte regeneration, liver cell transplantation or preclinical drug testing.

关键词： Mesenchymal stem cells Bone marrow Adipose tissue Transdifferentiation Hepatic lineage Liver cell transplantation.

SYNBIOCHEM Synthetic Biology Research Centre, Manchester-A UK foundry for fine and speciality chemicals production

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Synthetic and Systems Biotechnology 2016年第4期1卷 271-275页

作者： Le Feuvre RA carbonell p Currin A Dunstan M Fellows D Jervis AJ Rattray NJW Robinson CJ Swainston N Vinaixa M Williams A Yan C Barran p Breitling R Chen GG Faulon JL Goble C Goodacre R Kell DB Micklefield J Scrutton NS Shapira p Takano E Turner NJ Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals(SYNBIOCHEM) Manchester Institute of BiotechnologyFaculty of Life SciencesUniversity of ManchesterOxford RoadManchesterM139PTUnited Kingdom SYNBIOCHEM Data LeadSchool of Computer ScienceThe University of ManchesterManchesterM139PTUnited Kingdom SYNBIOCHEM Responsible Research and Innovation LeadAlliance Manchester Business SchoolUniversity of ManchesterManchesterM139PTUnited Kingdom

The UK Synthetic Biology Research Centre,SYNBIOCHEM,hosted by the Manchester Institute of Biotechnology at the University of Manchester is delivering innovative technology platforms to facilitate the predictable engineering of microbial bio-factories for fine and speciality chemicals *** provide an overview of our foundry activities that are being applied to grand challenge projects to deliver innovation in bio-based chemicals production for industrial biotechnology.

关键词： Synthetic chemicals Manchester

Role of aldehyde dehydrogenase 2 in ischemia reperfusion injury:An update

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World Journal of Gastroenterology 2018年第27期24卷 2984-2994页

作者： Arnau panisello-Roselló Alexandre Lopez Emma Folch-puy Teresa carbonell Anabela Rolo Carlos palmeira René Adam Marc Net Joan Roselló-Catafau Department of Experimental pathology Institute of Biomedical Research of Barcelona(IIBB)-CSICBarcelona 08036Spain Centre Hepatobiliare AP-HP Hopital Paul BrousseVillejuif 75008France Department of physiology Faculty of BiologyUniversitat de BarcelonaBarcelona 08036Spain Center for Neuroscience and Cell Biology University of CoimbraCoimbra 3004-517Portugal Institute Georges Lopez Lissieu 69380France

Aldehyde dehydrogenase 2(ALDH2) is best known for its critical detoxifying role in liver alcohol metabolism. However, ALDH2 dysfunction is also involved in a wide range of human pathophysiological situations and is associated with complications such as cardiovascular diseases, diabetes mellitus, neurodegenerative diseases and aging. A growing body of research has shown that ALDH2 provides important protection against oxidative stress and the subsequent loading of toxic aldehydes such as 4-hydroxy-2-nonenal and adducts that occur in human diseases, including ischemia reperfusion injury(IRI). There is increasing evidence of its role in IRI pathophysiology in organs such as heart, brain, small intestine and kidney; however, surprisingly few studies have been carried out in the liver, where ALDH2 is found in abundance. This study reviews the role of ALDH2 in modulating the pathways involved in the pathophysiology of IRI associated with oxidative stress, autophagy and apoptosis. Special emphasis is placed on the role of ALDH2 in different organs, on therapeutic "preconditioning" strategies, and on the use of ALDH2 agonists such as Alda-1, which may become a useful therapeutic tool for preventing the deleterious effects of IRI in organ transplantation.

关键词： Aldehyde dehydrogenase 2 4-hydroxy-2-nonenal autophagy Apoptosis Ischemia reperfusion injury preconditioning