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Current Helicobacter pylori treatment in 2014

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World Journal of Methodology 2015年第2期5卷 101-107页

作者： Fatih Ermis elif Senocak Tasci Department of Gastroenterology Duzce University Faculty of Medicine Department of Internal Medicine Duzce University Faculty of Medicine

Helicobacter pylori is one of the most commonly seen bacterium ***'s in the etiology of multiple gastrointestinal diseases,ranging from gastritis to gastric *** antimicrobial therapies,which are frequently prescribed empirically,are losing their effectivity as a result of the increasing antimicrobial *** the standard triple therapy is now leftespecially in areas with high-clarithromycin resistance due to decreased eradication rates,quadruple therapies are recommended in most regions of the ***,concomitant,sequential and hybrid therapies are *** is still a debate going on about the use of levofloxacin-based therapy in order to prevent the increase in quinolone *** no regimen can achieve the desired eradication rate,culture-guided individualized therapies are highly ***,statins and n-acetylcysteine are helpful as adjuvant therapies in order to increase the effectiveness of the eradication ***,we focused on different eradication regimens in order to highlight the current Helicobacter pylori treatment.

关键词： Helicobacter pylori Eradication Treatment Bismuth-quadruple therapy Sequential therapy Concomitant therapy Hybrid therapy

Bullous oral lichen planus:report of two cases

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中华医学杂志(英文版) 2003年第10期000卷 154-155页

作者： Berrin NSAL,S.elif GLTEKIN,Erol BAL,Benay TOKMAN Department of Periodentology Faculty of Dentistry Gazi University Department of Oral Pathology Faculty of Dentistry Gazi University Department of Maxillofacial Surgery Dental Clinic Air Force Hospital Etimesgut Department of Oral Pathology Faculty of Dentistry Gazi University Ankara Turkey Ankara Turkey Ankara Turkey Ankara Turkey

Effect of the COVID-19 pandemic on patients with presumed diagnosis of acute appendicitis

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World Journal of Clinical Cases 2022年第29期10卷 10487-10500页

作者： Sami Akbulut Adem Tuncer Zeki Ogut Tevfik Tolga Sahin Cemalettin Koc Emek Guldogan Ertugrul Karabulut elif Seren Tanriverdi Ali Ozer Surgery and Liver Transplant Institute Inonu University Faculty of MedicineMalatya 44280Turkey Department of Biostatistics and Medical Informatics Inonu University Faculty of MedicineMalatya 44280Turkey Department of Public Health Inonu University Faculty of MedicineMalatya 44280Turkey Department of Surgery Inonu University Faculty of MedicineMalatya 44280Turkey Department of Medical Microbiology Inonu University Medical FacultyMalatya 44280Turkey

BACKGROUND Acute appendicitis(AAp) is the most frequent cause of acute abdominal pain,and appendectomy is the most frequent emergency procedure that is performed *** coronavirus disease 2019(COVID-19) pandemic has caused delays in managing diseases requiring emergency approaches such as AAp and *** To compare the demographic,clinical,and histopathological outcomes of patients with AAp who underwent appendectomy during pre-COVID-19 and COVID-19 *** The demographic,clinical,biochemical,and histopathological parameters were evaluated and compared in patients who underwent appendectomy with the presumed diagnosis of AAp in the pre-COVID-19(October 2018-March 2020) and COVID-19(March 2020-July 2021) *** Admissions to our tertiary care hospital for AAp increased 44.8% in the COVID-19 ***-19(n = 154) and COVID-19(n = 223) periods were compared for various parameters,and we found that there were statistically significant differences in terms of variables such as procedures performed on the weekdays or weekends [odds ratio(OR):1.76;P = 0.018],presence of AAp findings on ultrasonography(OR:15.4;P < 0.001),confirmation of AAp in the histopathologic analysis(OR:2.6;P = 0.003),determination of perforation in the appendectomy specimen(OR:2.2;P = 0.004),the diameter of the appendix(P < 0.001),and hospital stay(P = 0.003).There was no statistically significant difference in terms of interval between the initiation of symptoms and admission to the hospital between the pre-COVID-19(median:24 h;interquartile range:34) and COVID-19(median:36 h;interquartile range:60) periods(P = 0.348).The interval between the initiation of symptoms until the hospital admission was significantly longer in patients with perforated AAp regardless of the COVID-19 or pre-COVID-19 status(P < 0.001).CONCLUSION The present study showed that in the COVID-19 period,the ultrasonographic determination rate of AAp,perforation rate of AAp,and duration of hospital

关键词： SARS-CoV-2 COVID-19 pandemic Acute appendicitis Perforated appendicitis Negative appendectomy

A novel mutation of SGK-1 gene in central serous chorioretinopathy

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International Journal of Ophthalmology(English edition) 2015年第1期8卷 23-28页

作者： Mahmut Akyol Muhammet Kazιm Erol Ozdemir Ozdemir Deniz Turgut Coban Ahmet Burak Bilgin Esin Sogutlu Sari elif Betul Turkoglu Department of Medical Biology and Genetics Akdeniz University Faculty of Medicine Department of Ophthalmology Antalya Education and Research Hospital Department of Ophthalmology Zekai Tahir Burak Women's Health Education and Research Hospital Department of Ophthalmology Akdeniz University Faculty of Medicine Department of Ophthalmology Balιkesir University Faculty of Medicine

AIM: To investigate the association of serum glucocorticoid kinase gene-1(SGK-1) DNA variants with chronic central serous chorioretinopathy(CSC).METHODS: We enrolled 32 eyes of 32 patients who were diagnosed with chronic CSC and composed 32 normal eyes as a control group. Peripheral blood was used for DNA extraction and polymerase chain reaction amplification. SGK1 gene was sequenced by using Big Dye Terminator v3.1 cycle sequencing Kit(Applied Biosystems, Foster City, CA, USA). The SGK-1 gene and its variants were investigated in CSC patient group and control ***: We identified a new polymorphism M32 V in two person in the patient group [Minor allele frequency(MAF) =0.009] on the region of 1-60 amino acids. The rs1057293 was located in the encoder region of the SGK- 1 gene but not associated with CSC(P =0.68). An intrinsic rs1743966 is also not associated(P =0.28).CONCLUSION: The new polymorphism M32 V is located on the region of 1-60 amino acids which is necessary for localization to the mitochondria in CSC patient. This mutation is probably important for the energy metabolism and plays an important role in the cellular response to hyperosmotic stress and other stress stimuli. Both rs1057293 and rs1743966 are not associated with CSC.

关键词： central serous chorioretinopathy mutation polymerase chain reaction serum glucocorticoid kinase gene-1

Paroxetine overdose during pregnancy

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Forensic Sciences Research 2021年第4期6卷 237-239页

作者： Selin Acar Hilal Erol elif Keskin Arslan Nusret Uysal BarışKaradaş Tijen Kaya Temiz Yusuf Cem Kaplan Faculty of Medicine Department of Pharmacologyizmir Katip celebi UniversityizmirTurkey Terafar(izmir Katip celebi University Teratology information Training and research center)izmirTurkey

Paroxetine is a selective serotonin reuptake inhibitor(SSRI)used in the treatment of depression and anxiety *** some epidemiological studies,slightly increased risks of major malformations and cardiac malformations have been reported following paroxetine exposure in the first trimester of ***,such findings have been *** is only one report of any overdose of an SSRI during pregnancy,and that involved *** aim of this case report was to describe the impact of a paroxetine overdose in the first trimester of pregnancy on the health of the foetus.A 21-year-old mother of one child who was pregnant with a second child was prescribed 20 mg/day paroxetine hydrochloride for the treatment of anxiety/*** patient ingested 15 or 1620-mg tablets of paroxetine hydrochloride(300-320 mg)during the 5th week of pregnancy as a suicide *** 15 min of ingestion,she was admitted to hospital and treated for *** evidence of maternal SSRI intoxication was observed after *** patient consulted our teratology information service for further risk assessment regarding possible major congenital malformations following the paroxetine *** were unable to find previous reports of paroxetine overdose during pregnancy in the *** timely administration of the overdose treatment and the lack of maternal intoxication symptoms were considered positive for the foetal well-being,and the patient was referred for perinatology and psychiatry follow-ups.A healthy,3500-g male infant was born at 38 weeks’gestation,and his development at the age of 2 years was *** is the first reported case of paroxetine overdose during *** studies are needed to evaluate pregnancy outcomes after SSRI overdose.

关键词： Forensic sciences forensic toxicology paroxetine overdose teratogenicity case report

Determination and Evaluation of the Self-Compassion Levels of the Students Studying in the Sport Sciences Faculties of Universities

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Journal of Sports Science 2016年第1期4卷 39-44页

作者： Taner Yilmaz elif Top Mustafa Akil Faculty of Sport Sciences Usak University Usak 64000 Turkey

The present study has been conducted in order to determine the self-compassion levels of the students studying in various departments of the faculties of sports sciences and performing sports, and thus to find out whether certain variables such as their branch, department and families have an effect on their self-compassion levels. The ＂Self-compassion Scale＂ was used as the data collection tool in the study. In the present study, when the self-compassion levels of the students of the faculties of sports sciences were evaluated by various variables, it was found that the self-compassion levels of the students of Mugla University were significantly higher than those of the students of Ankara University, that the self-compassion levels of the students studying in the department of teaching were higher than those of the students studying in the department of coaching, and that the self-compassion levels of the students performing the branch of football were significantly higher than those of the students performing the branch of volleyball. When the students were compared based on the cities they live, it was found that the students living in the province of Mugla had significantly higher levels of self-compassion comparing to the students living in the province Ankara. Consequently, it was determined that the self-compassion levels of the students studying in various departments of the faculties of sports sciences were moderate, and that the differences in the province, department and the sports branch had an effect on the levels of self-compassion.

关键词： Self-compassion exercise physical education students.

The Influence of Heat Treatment on Interaction of Green Tea Flavonoids with Milk Proteins

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Journal of Agricultural Science and Technology(B) 2018年第8期8卷 530-541页

作者： Zerrin Yüksel Onür elif Avci Department of Food Technology Bayramic Vocational Collegecanakkale Onsekiz Mart University Canakkale Turkey Department of Food Engineering Hacettepe University Beytepe Ankara Turkey

Several heat treatment norms are applied in the dairy industry during the manufacture of various products. The knowledge on the influence of temperature on the proteins-flavonoid binding is critical for optimization of process conditions. The aim of this study was to establish the effect of heat treatment on the interaction between milk proteins and flavonoids and also determine when to apply heat treatment. Reverse-phase high-performance liquid chromatography (RP-HPLC) analysis revealed that free flavonoids decreased in the presence of milk proteins and a binding ratio (%) was calculated based on this decrease. Three different heat treatment norms were selected (80, 85 and 90℃×10 min). Analyses were carried out in both sodium caseinate and skimmed milk samples to observe the possible effect of milk serum proteins on the interaction. The binding ratio between flavonoids and proteins was found to be higher in the samples where green tea extract (GTE) was added before heat treatment than in the samples where GTE was added after heat treatment in both the skimmed milk and sodium caseinate systems. Results of protein surface hydrophobicity (PSH) index and protein partition also demonstrated that heat treatment must be applied after the addition of GTE to improve the amount of GTE binding to milk proteins.

关键词： Flavonoids milk proteins green tea heat treatment RP-HPLC.

An Intersting Case: A Long Pin in the Nose

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International Journal of Clinical Medicine 2014年第17期5卷 1065-1067页

作者： Ilhan Unlu elif Nisa Unlu Department of ENT Duzce University Medical Faculty Duzce Turkey Department of Radriology Duzce University Medical Faculty Duzce Turkey

Intranasal foreign bodies are very common problems for ENT practitioners. However, very few case reports of a long pin in the nose are described in the literature. Our case had a pin measured as 33.9 millimeters in the right nasal vestibule, but the patient was not aware of it when she came to us. Actually she was suffering from a headache and nasal obstruction. After removal of the foreign body, the patient’s complaints were resolved.

关键词： Foreign Body Pin Nasal Cavity

Abrasive Wear Behavior of Different Thermal Spray Coatings and Hard Chromium Electroplating on A286 Super Alloy

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Advances in Materials Physics and Chemistry 2012年第4期2卷 68-70页

作者： Macid Nurbas elif Nazik Atabay Durul ESOGU Chemical Eng.Dept.EskisehirTurkey Air Supply and Maintenance Center Command Eskisehir Turkey

In cases of decorative and functional applications, chromium results in protection against wear and corrosion combined with chemical resistance and good lubricity. However, pressure to identify alternatives or to improve conventional chromium electroplating mechanical characteristics has increased in recent years, related to the reduction in the fatigue strength of the base material and to environmental requirements (1). In the present study plasma sprayed coatings (aluminum oxide, Co-28Mo-8Cr-2Si, tungsten carbide, chrome carbide) and electrolytic hard chrome coatings abrasive wear properties have been compared. The wear tests were conducted with a Taber abraser, at room temperature.

关键词： Thermal Spray Abrasive Wear Electrodeposited Hard Chrome Hardness SEM