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Effect of 1%brinzolamide and 0.5%timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification

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International Journal of Ophthalmology(English edition) 2013年第6期6卷 851-854页

作者： Kemal rnek Nesrin Byktortop Nurgl rnek Reyhan Ogurel Inci elif Erbahceci Zafer Onaran Department of Ophthalmology School of MedicineKinkkale University

AIM:To evaluate the effect of brinzolamide-timolol fixed combination on intraocular pressure(IOP)after cataract ***:The study included 92 eyes of 87 patients who underwent cataract surgery and intraocular lens *** scheduled for phacoemulsification were assigned to 1 of 2 *** treatment group received 1 drop of brinzolamide-timolol fixed combination immediately after surgery,and the control group received no *** IOP was measured preoperatively and at 2h and 24h ***:The mean IOP change was lower in the treatment group than in the control group at 2h *** difference between the mean IOP values of the two groups at 2h postoperatively was found to be statistically ***-four hours after the surgery,the mean IOP change was still higher in the control group when compared to the treatment ***:The fixed combination brinzolamidetimolol can effectively reduce IOP after cataract surgery.

关键词： brinzolamide timolol cataract surgery

Coexistence of ocular cicatricial pemphigoid with Stevens Johnson syndrome

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International Journal of Ophthalmology(English edition) 2013年第3期6卷 411-412页

作者： Hande Taylan Sekeroglu Firas Simsek elif Erdem Ibrahim Inan Harbiyeli Meltem Yagmur Reha Ersoz Department of Ophthalmology Cukurova University Faculty of Medicine

Dear Sir, I am Dr. Hande Taylan Sekeroglu, from the Ophthalmology Department of Cukurova University Faculty of Medicine. I want to present a case of recalcitrant ocular cicatricial pemphigoid (OCP) which was coinciden... 详细信息

关键词： Coexistence of ocular cicatricial pemphigoid with Stevens Johnson syndrome oral OCP Figure

Heavy metal concentrations in macroalgae species from Sinop coasts of the Southern Black Sea

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Journal of Coastal Life Medicine 2016年第11期4卷 841-845页

作者： Levent Bat elif Arici Department of Hydrobiology Fisheries FacultySinop University57000SinopTurkey

Objective:To determine the concentrations of Fe,Zn,Ni,Cu,Mn,Pb,Cd and Co in macroalgae from Sinop coasts of the Sounthern Black ***:Chlorophyta-green algae(Chaetomorpha spp.,Cladophora spp.,Ulva linza,Ulva intestinalis,Ulva lactuca,Ulva rigida);Ochrophyta-brown alga[Cystoseira barbata(***)]and Rhodophyta-red algae(Ceramium spp.,Corallina panizzoi)were collected seasonally in the year 2010 from the upper infralittoral zone of inner harbour,outer harbour,Gerze and Ayancık of Sinop coasts of the Black *** samples were analysed by atomic absorption spectrophotometer in order to determine heavy metal levels in different algal division species along Sinop coasts and to provide information of marine environment quality as marine strategy framework directive is aimed to ensure good environmental status of the seas by 2020 in the European ***:The results showed that metal concentrations in all studied green algae,brown alga and red algae increase in the order:Cd

关键词： Heavy metals Macroalgae Black Sea Sinop Coast Marine strategy framework directive

Giant myxoinflammatory fibroblastic sarcoma with bone invasion:a very rare clinical entity and literature review

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Chinese Journal of Cancer 2014年第8期33卷 406-410页

作者： Guray Togral Murat Arikan elif Aktas Safak Gungor Department of Orthopaedics and Traumatology Oncology Training and Research HospitalVatan caddesi 06200DemetevlerAnkaraTurkey Department of Radiology Oncology Training and Research HospitalVatan caddesi 06200DemetevlerAnkaraTurkey

Myxoinflammatory fibroblastic sarcoma(MIFS) is a rare low-grade, malignant soft tissue tumor that is usually observed in the extremities of adult patients. Magnetic resonance imaging findings for this tumor type have rarely been reported. We report a case involving the distal left femur of a middle-aged man and tumoral invasion of the bone, which, to our knowledge, has been previously described only once. He was treated with distal femoral tumor resection and reconstruction with a modular prosthesis. Histopathologic diagnosis confirmed MIFS. We reviewed literature of the diagnostic imaging and bone invasion findings associated with this tumor type.

关键词：纤维母细胞文献综述浸润肉瘤肿瘤侵袭实体临床巨人

An Investigation of Postmortem Urotensin II Receptor Levels in Brain and Kidney Tissues in a Rat Model of Cardiac Ischemia

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Journal of Forensic Science and Medicine 2018年第1期4卷 1-6页

作者： Mustafa Talip Sener Erol Akpinar elif Cadirci Zekai Halici Irfan Cinar Ahmet Nezih Kok Departments of Forensic Medicine and Pharmacology Faculty of MedicineAtaturk UniversityErzurum 25240Turkey

This study aimed to investigate changes in postmortem urotensin Ⅱ receptor(UTR)levels in brain and kidney tissues in a rat model of cardiac *** rats were divided into two groups:a control group and a cardiac ischemia-induced *** ischemia was created by an intraperitoneal injection of a single lethal dose of isoproterenol(ISO;850 mg/kg).Plasma UT,blood urea nitrogen,and creatinine levels were determined 0 h *** and kidney UTR mRNA expression levels were determined 0,1,3,6,12,24,4&and 72 h *** histopathological appearance of brain and kidney tissues was also *** UT and plasma creatinine levels were increased in the cardiac ischemia-induced group as compared with those in the control group(P<0.001).Ischemia resulted in histopathological changes in brain and cerebellum *** morphological evaluation revealed Purkinje cell degeneration(P=0.037)and dark neurons(P=0.004).The UTR expression level decreased after 1 h postmortem in the brain and after 3 h postmortem in the kidneys in the cardiac ischemia-induced group as compared with that in the control group(P<0.001).The observed changes in UTR expression levels may be valuable in clinical practice in the field of forensic *** changes may be used as a marker in postmortem evaluations of sudden death caused by ischemia-induced cardiac shock.

关键词： Brain cardiac ischemia kidney postmortem urotensin II receptor expression

The apoptotic effect of ozone therapy on mitochondrial activity of highly metastatic breast cancer cell line MDA-MB-231 using in vitro approaches

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Journal of Interventional Medicine 2022年第2期5卷 64-71页

作者： Merve Yildirim Selen Erkisi Hazal Yilmaz Naz Unsal elif inac Yldray Tanrnver Polen Kocak Departnent of Genetics and Bioenginering Facaly of Engineering and Architecture Yeditepe University26 Agustos CampusKaqrisdagt CadKaytsdag34755IstanbulTurkey Infirity Regnerative Clini Thy Sites YoluUlus34347IstanbulTurkey Department of Biomedical Engineering Faculy of Enginering Itirve Universit Vadi CampusAzerbaycan CadSariyer34396IstanbulTurkey

Ozone(O) gas is the triatomic state of oxygen and it is used as a disinfection agent due to its strong oxidizing effect, since its discovery in the mid-nineteenth century. Ozone therapy is also an alternative therapeutic approach for some diseases like circulatory disorders, AIDS, asthma, cardiovascular diseases, and certain types of cancer by increasing the oxygen levels in the blood by external addition of ozone to the body. In this study, the therapeutic potential of ozone therapy was examined by inhibiting the growth of breast cancer cells in a dose-dependent procedure. Ozone concentrations varying from 5 to 20 μg/ml were applied to the MDA-MB-231, human breast adenocarcinoma and HUVEC, human umbilical vein endothelium, cell lines, and MDA cells demonstrated an increased rate of death while its migration potential decreases. RT-PCR analysis showed mRNA expression levels of pro-apoptotic genes demonstrated higher folds in MDA cells after 10 μg/ml treatment. In the same context,Annexin V/PI and cell cycle analysis also concluded that ozone therapy causes apoptotic cell death on breast tumor cells. The use of ozone therapy for cancer treatment requires further and extensive research. However, this research has shown that ozone therapy is a promising source for cancer treatment in a way by inhibiting the proliferation of breast tumor cells.

关键词： Ozone therapy Antioxidants Apoptosis Breast cancer

A rare cause of chronic ataxia in childhood:ganglioneuroma

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World Journal of Pediatrics 2018年第2期14卷 204-206页

作者： elif Acar Arslan Tülay Kamasak Betül Diler Turgut ismail Saygin Haluk Sarihan Ali Cansu Department of Pediatric Neurology Karadeniz Technical University School of MedicineFarabi StreetN:6461080 TrabzonTurkey Department of Pathology Karadeniz Technical University School of MedicineFarabi StreetN:6461080 TrabzonTurkey Department of Pediatric Surgery Karadeniz Technical University School of MedicineFarabi StreetN:6461080 TrabzonTurkey

Ganglioneuroma is an extremely rare cause of ataxia in childhood,the only descriptions of which are in the form of case reports[1,2].Ganglioneuroma can be asymptomatic in the abdominal and thoracic region,or else can ... 详细信息

关键词： rare thoracic pain

Tumor budding as a potential prognostic marker in determining the behavior of primary liver cancers

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World Journal of Hepatology 2023年第6期15卷 775-785页

作者： Betul Unal Mennan Yigitcan Celik elif Ocak Gedik Cumhur Ibrahim Bassorgun Gulsum Ozlem Elpek Department of Pathology Akdeniz University Medical SchoolAntalya 07070Turkey

Hepatocellular(HCC)and intrahepatic cholangiocarcinoma(ICC),the most common primary tumors of the liver,are among the most important causes of cancer deaths *** patients with primary liver tumors are frequently diagnosed at an advanced stage and have high mortality,many efforts have been made to identify new markers to determine their behavior and treatment,similar to those in other solid organ ***,morphological assessment of tumor budding(TB)has been revealed as a promising prognostic finding to predict tumor behavior and survival across several different tumor ***,the TB score in colorectal cancer has been revealed as an important parameter in pathology report protocols to determine the course of the *** the liver,despite enormous data showing that many mechanisms involved in TB are associated with tumor behavior in both HCC and ICC,studies focusing on the role of TB in predicting the behavior and prognosis of these tumors have started to be investigated very *** purpose of this review is to present data about TB in primary tumors of the liver,pointing out the potential role of this parameter in determining the course of the disease,and emphasize the need to increase the number of further studies focusing on the evaluation of this parameter with an overview of the mechanisms involved in TB.

关键词： Tumor budding Hepatocellular carcinoma Cholangiocarcinoma Prognosis Liver cancer Epithelial-mesenchymal transition

Solid amine sorbents for CO_(2) capture by chemical adsorption: A review

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Petroleum 2017年第1期3卷 37-50页

作者： elif ErdalÜnveren Bahar Ozmen Monkul S¸erife Sarıoglan Nesrin Karademir Erdogan Alper Institute of Chemical Technology TUBITAK Marmara Research CenterGebze 41470KocaeliTurkey Chemical Engineering Department Hacettepe UniversityBeytepe 06800AnkaraTurkey

Amines are well-known for their reversible reactions with CO_(2),which make them ideal for CO_(2) capture from several gas streams,including flue *** this respect,selective CO_(2) absorption by aqueous alkanolamines is the most mature technology but the process is energy intensive and has also corrosion *** disadvantages can be diminished to a certain extent by chemical adsorption of CO_(2) *** most important element of the chemical adsorption of CO_(2) involves the design and development of a suitable adsorbent which consist of a porous support onto which an amine is attached or *** an adsorbent is often called as solid amine *** review covers solid amine-based studies which are developed and published in recent ***,the review examines several different types of porous support materials,namely,three mesoporous silica(MCM-41,SBA-15 and KIT-6)and two polymeric supports(PMMA and PS)for CO_(2) *** is given to the synthesis,modifications and characterizations-such as BET and PXRD data-of *** of these supports to obtain a solid amine sorbent through impregnation or grafting is reviewed *** is given to the adsorption mechanisms,material characteristics,and synthesis methods which are discussed in *** amount of original data are also presented which makes this review ***,relevant CO_(2) adsorption(or equilibrium)capacity data,and cyclic adsorption/desorption performance and stability of important classes of solid amine sorbents are critically *** include severa PEI or TEPA impregnated adsorbents and APTES-grafted systems.

关键词： Amine-impregnation Amine-grafting CO_(2)capture Chemical adsorption Mesoporous silica Solid amine sorbent Polymeric support Temperature swing adsorption