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Profile of Patients with Stroke and Disorders of the Vocal Tract

World Journal of Neuroscience 2017年第1期7卷 82-94页

作者： Lina Claudia Pereira Lopes Daniel Almeida da Costa Marcus Vinicius de Mello Pinto Aline Ronis Sampaio Lamara Laguardia Valente Rocha Isabela Nardoni Bernardes Rafael Batista Ferreira elias sobreira sathler R. R. B. T. Vieira Luiz Gioseffi Jannuzzi School Hospital of the Dom André Arcoverde Foundation Valen&ccedil a Brazil The Medical School at the Center of Higher Education of Valenç a Valen&ccedil a Brazil University of Business and Social Sciences Bueinos Aires Argentina The Cellurare Institute Center of Laser Treatment and Cell Therapy Petrópolis Brazil The Medical School at the Health Sciences Institute of the University Center of Caratinga Caratinga Brazil

Background: The present work aims to characterize the profile of patients with stroke treat at a hospital located in the Region of the Mata of Minas Gerais, Brazil, considering the findings of the clinical vocal tract, kind of stroke, age and gender of such patients. Methodology: To obtain data, the clinical profile of 133 patients with a clinical or tomography diagnosis of stroke was analyzed, and the results were presented in percentage. For quantitative data average and analysis the tests were done with associations that held χ2 test, and for significance it was considered p Results: From the total of patients, 63 were women, accounting for 47.4% and the other 52.6% were males. Clinically, they were characterized with the highest percentage for ischemic stroke (89.4%) compared to the hemorrhagic type (10.6%). Most of them were referred for computed tomography (86.5%) and remained hospitalized for an average of 6.496 ± 7.372 days. Similar percentages were obtained in the analysis of the population in question, when considering if they had (54.1%) or not (49.6%) any damage in their speech, language skills or swallowing. There were different types of disabilities in patients with stroke. Men with an average age of 69.8 ± 13.9 presents mostly ischemic stroke, and the majority of patients with stroke had hemiplegia and abnormalities of the vocal tract, dysphasia, and aphasia. While older patients had an ischemic stroke and were presented with left hemiplegia, the younger ones suffered from hemorrhagic strokes that caused a disability characterized as right hemiplegic. Conclusion: Our results show important conclusions regarding the clinical evolution of the vocal tract of patients who suffered strokes during the period of the analysis, being useful for better comprehension of how the vocal tract from these patients evolved according to the kind of stroke, sex and age also allowing a contraposition with other future statistics periods available in literature. It can al

关键词： Speech Disorders Swallowing Disorders Stroke Vocal Tract

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Main Microbial Genres and Its Profile of Resistance and Sensitivity to Antimicrobials Used in the Treatment of Oncological Patients with Febril Neutropenia

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Journal of Biosciences and Medicines 2018年第1期6卷 34-50页

作者： Hélvecio Cardoso Póvoa Richard Raphael Borges Tavares Vieira elias sobreira sathler Isabela Nardoni Bernardes Rafael Batista Ferreira Mário Henrique Couto Lima Thiago Sande Miguel Nayrton Kalys Cruz dos Anjos Lamara Laguardia Valente Rocha Daniel Almeida da Costa Federal Fluminense University Niterói Brazil The Medical School at the Center of Higher Education of Valenç a Valen&ccedil a Brazil The Medical School at the Health Sciences Institute of the University Center of Caratinga Caratinga Brazil

Objective: To determine the main microbial genotypes and their antimicrobial resistance and susceptibility profile commonly used in the treatment of oncologic patients with febrile neutropenia, carried out through the review of the clinical histories of the patients’ medical records at the Hospital do Cancer de Muriaé-Fundacao Cristiano Varella. Methods: Quantitative research, determined the susceptibility profile of microorganisms in patients with febrile neutropenia from April 2007 to April 2008 by reviewing clinical histories of patients’ medical records at the referred hospital. Results: Of the total of 8 patients evaluated with Gram-negative microorganisms, 50% of the patients were female and 50% were male. Of the 18 patients evaluated with Gram-positive microorganisms 66% were female and 34% male. Gram-positive bacteria are prevalent and cause around 60% of documented bacteremias, although Gram-negative bacteria are more common in febrile neutropenic patientes. Conclusion: Exaggerated use of antimicrobials in hospitalized patients leads to the suppression of drug-sensitive microorganisms from the intestinal flora and promotes the persistence and growth of resistant bacteria. The antibiotic should be used in a curative manner with other therapeutic measures with the determined bacterial infection.

关键词： Febrile Neutropenia Antimicrobial Resistance Oncologic Patients

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Relationship of Density of Specific Prostate Antigen (DPSA) with Prostate Histopathology: A Comparative Study of Patients Addressed in a School Hospital

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Journal of Biosciences and Medicines 2017年第3期5卷 105-111页

作者： Marcos Benedito Figueiredo Brandã o Maria Benedita Figueiredo Brandã o elias sobreira sathler Richard Raphael Borges Tavares Vieira Carolina Cadinelli Vieira Pedro Kozlowsky de Alencar Marcus Vinicius de Mello Pinto Lamara Laguardia Valente Rocha Lina Claudia Pereira Lopes Daniel Almeida da Costa Carlos Henrique Diniz Branco Luiz Gioseffi Jannuzzi School Hospital of the Dom Andre Arcoverde Foundation Valen&ccedil a Brazil Universidade Está cio de Sá Rio de Janeiro Brazil The Medical School at the Center of Higher Education of Valenç a Valen&ccedil a Brazil The Cellurare Institute Center of Laser Treatment and Cell Therapy Petr&oacute polis Brazil The Medical School at the Health Sciences Institute of the University Center of Caratinga Caratinga Brazil

Background: The prostate is the site of problems that have great clinical relevance. Beside this, the alterations in their volume can be divided into benign or malignant pathologies, but of multifactorial cause and there is no examination that alone is reliable for the diagnosis. Despite the evolution of the various methods of diagnostic imaging in the evaluation of pelvic diseases, the diagnosis of prostate cancer still requires histological confirmation obtained by transrectal ultrasound guided biopsy, a procedure that is generally safe and well tolerated by the patients. The most common histological type found in prostate biopsies is adenocarcinoma. Methodology: The objective of this study was to study the values of density of the prostate-specific antigen (DPSA) compared to histopathological results of prostate biopsy, patients attended at the Urology Outpatient Clinic of the Luiz Gioseffi Jannuzzi School Hospital from 1999 to 2007, using Exploratory, retrospective and documentary descriptive study. The sample was divided into groups of patients with adenocarcinoma and patients without adenocarcinoma, who presented only benign prostatic hyperplasia. Results: Of the 251 patients undergoing prostate biopsy, 124 were diagnosed with adenocarcinoma and 127 without adenocarcinoma. It was observed in this study that the DPSA was higher in adenocarcinoma than in the cases of patients with prostatic hyperplasia alone, and could therefore be used as an auxiliary tool in both diagnosis and follow-up of patients with adenocarcinoma. Conclusion: In this study, it can be observed that DPSA was higher in patients presenting with adenocarcinoma than in patients presenting only Benign Prostatic Hyperplasia (BPH), reinforcing its promising role to assist in the diagnosis and follow-up of patients with adenocarcinoma.

关键词： Prostate Cancer Adenocarcinoma Benign Prostatic Hyperplasia Prostate Biopsy

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Study of Effects of Photodynamic Therapy(PDT),in Scar-Induced Skin Wounds in Rats Wistar:The New Clinical Perspective for Ulcers

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Modern Research in Inflammation 2017年第1期6卷 1-8页

作者： Marcus Vinicius de Mello Pinto Aline Ronis Sampaio Reggiani Vilela Goncalves Carlos Eduardo Tenorio da Veiga Lamara Laguardia Valente Rocha Daniel Almeida da Costa Lina Claudia Pereira Lopes Rafael Batista Ferreira Pamela Mara Cainelli Valim Kellen Regina Rodrigues Chaveiro elias sobreira sathler Richard Raphael Borges Tavares Vieira Isabela Nardoni Bernardes Medical School of the University of Buenos Aires Bueinos AiresArgentina The Cellurare Institute Center of Laser Treatment and Cell Therapy PetropolisBrazil Department of Cellular and Structural Biology of Federal University of Vicosa VicosaBrazil Clinical Hospital of Correas Rio de JaneiroBrazil The Medical School at the Health Sciences Institute of the University Center of Caratinga CaratingaBrazil The Medical School at the Center of Higher Education of Valenca ValencaBrazil Luiz Gioseffi Jannuzzi School Hospital of the Dom Andre Arcoverde Foundation ValencaBrazil

Photodynamic therapy today is becoming an important role in the healing of lacerated tissues, since it has therapeutic resources capable of accelerating this process. One treatment option is the clinical phototherapy, and Photodynamic Therapy (PDT) is being widely used. This study aims to evaluate the effect of PDT on the healing of skin wounds in rats. We used a sample of 39 male rats Wistar divided into three groups, a control, a PDT-treated green and red with the last PDT. After 24 hours before the surgical incisions, PDT was used in both groups for 6 minutes and was evaluated in histological level, the inflammatory reaction and the repair process. The results showed that the granulation tissue was more developed in the irradiated group than in the control group and the amount of chronic inflammatory cells (monocytes, macrophages, lymphocytes and plasma cells) predominated with green phototherapy. The epithelialization in the wound margins and scarring with better quality occurred with red PDT (640 nm), which the higher deposition was of collagen. However, phototherapy not collimated of 640 nm (red) resulted in better anti-inflammatory effects. Given these answers with phototherapy not collimated green (525 nm) and red (640 nm), we conclude that the use of these wavelengths is possible with benefits, mainly with red LED.

关键词： Healing Photodynamic Therapy(PDT) Light Emitting Diodes(LEDs) Ulcer

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