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A signal-substrate match in the substrate-borne component of a multimodal courtship display

Current Zoology 2010年第3期56卷 370-378页

作者： Damian O.elias Andrew C.MASON Eileen A.HEBETS Department of Environmental Science Policy and ManagementUniversity of California Integrative Behaviour and Neuroscience Group University of Toronto Scarborough School of Biological Sciences University of Nebraska

The environment can impose strong limitations on the efficacy of signal transmission. In particular, for vibratory communication, the signaling environment is often extremely heterogeneous at small scales. Nevertheless, natural selection is expected to select for signals well-suited for effective transmission. Here, we test for substrate-dependent signal efficacy in the wolf spider Schizocosa stridulans Strattou 1991. We first explore the transmission characteristics of this important signaling mo- dality by playing recorded substrate-bome signals through three different substrates （leaf litter, pine litter, and red clay） and measuring the propagated signal. We found that the substrate-bome signal of S. stridulans attenuates the least on leaf litter, the substrate upon which the species is naturally found. Next, by assessing mating success with artificially muted and non-muted males across different signaling substrates （leaf litter, pine litter, and sand）, we explored the relationship between substrate-bome signaling and signaling substrate for mating success. We found that muted males were unsuccessful in obtaining copulations re- gardless of substrate, while mating success was dependent on the signaling substrate for non-muted males. For non-muted males, more males copulated on leaf litter than any other substrate. Taken together, these results confLrm the importance of sub- strate-bome signaling in S. stridulans and suggest a match between signal properties and signal efficacy - leaf litter transmits the signal most effectively and males are most successful in obtaining copulations on leaf litter [Current Zoology 56 （3）： 370-378, 2010].

关键词： Environmental heterogeneity Sensory drive Mate choice Communication

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Gut microbiome in alcohol use disorder:Implications for health outcomes and therapeutic strategies-a literature review

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World Journal of Methodology 2024年第1期14卷 33-44页

作者： Ilias Koutromanos Evangelia Legaki Maria Gazouli Efthimios Vasilopoulos Anastasios Kouzoupis elias Tzavellas First Department of Psychiatry "Aiginition"HospitalSchool of MedicineNational and Kapodistrian University of AthensSchool of MedicineNational and Kapodistrian University of AthensAthens 11528Greece Department of Basic Biological Science School of MedicineNational and Kapodistrian University of AthensAthens 11527Greece Department of Basic Medical Sciences Medical SchoolNational and Kapodistrian University of AthensAthens 11527Greece

Alcohol use disorder(AUD)represents a major public health issue which affects millions of people globally and consist a chronic relapsing condition associated with substantial morbidity and *** gut microbiome plays a crucial role in maintaining overall health and has emerged as a significant contributor to the pathophysiology of various psychiatric *** evidence suggests that the gut microbiome is intimately linked to the development and progression of AUD,with alcohol consumption directly impacting its composition and *** review article aims to explore the intricate relationship between the gut microbiome and AUD,focusing on the implications for mental health outcomes and potential therapeutic *** discuss the bidirectional communication between the gut microbiome and the brain,highlighting the role of microbiotaderived metabolites in neuroinflammation,neurotransmission,and mood ***,we examine the influence of AUD-related factors,such as alcohol-induced gut dysbiosis and increased intestinal permeability,on mental health ***,we explore emerging therapeutic avenues targeting the gut microbiome in the management of AUD,including prebiotics,probiotics,and fecal microbiota *** the complex interplay between the gut microbiome and AUD holds promise for developing novel interventions that could improve mental health outcomes in individuals with AUD.

关键词： Alcohol use disorder Gut microbiome Dysbiosis

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Designing and Implementing A Marine Propeller Test Platform

Designing and Implementing A Marine Propeller Test Platform

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作者： elias Taalab 杭州电子科技大学

学位级别：硕士

Marine propellers are essential components of many watercrafts,and their performance depends on various factors such as geometry,material,speed,and pitch ***,in this study,we demonstrate the main elements and working principle of a marine *** also explain the main principle of lift and drag force and its effects on propeller's design and ***,we demonstrated how a propeller can be tested in realistic *** studying previous designs and patents of marine propeller test platforms,some limitations have been found and *** address these limitations,the main objective of this study has been set to develop a propeller test platform that can measure the thrust and torque of different propellers with high accuracy and *** setting the suitable requirements and designing the propeller test platform,we propose a new design of a marine propeller test platform that uses a swing arm mechanism to fix the propeller under water and sense its thrust force while keeping the main motor and the frame *** design allows us to get high sensitivity measurements continuously and precisely without being affected by the motor and frame *** the mentioned design,a well-balanced mechanism has been achieved with high sensitivity thrust measuring *** platform could sense small forces of about 0.001 kgf,which is essential for evaluating the performance of low-thrust ***,we achieved a power train that can deliver up to 22 k W of power to the propeller with up to 1500 rpm of rotational speed suitable for most mid-sized propellers,and that with torque consumption up to 70 N·m which allows us to test a wide range of propellers with different power and speed *** to the previously used platform,this new design can be up to 120 times faster than old test platforms when it comes to changing *** achieved propeller test platform can hold up to 2500 N of thrust force an

关键词： Marine Propeller Test Rig Test Platform Propeller Coefficients

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Herbal Medicines Prevent the Development of Atopic Dermatitis by Multiple Mechanisms

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Chinese Journal of Integrative Medicine 2019年第2期25卷 151-160页

作者： MAN Mao-qiang HU Li-zhi Peter M.elias Dermatology Service Veterans Affairs Medical Center Department of Dermatology University of California San Francisco School of Basic Medical Sciences Tianjin Medical University

Atopic dermatitis(AD) is among the most common skin disorders in humans. Although a variety of regimens are available for the treatment of AD, preventive approaches are limited. Recent studies have demonstrated that certain naturally-occurring herbal medicines are effective in preventing the development of AD via divergent mechanisms, such as inhibiting cytokine and chemokine expression, IgE production, inflammatory cell infiltration, histamine release, and/or enhancement of epidermal permeability barrier function. Yet, they exhibit few adverse effects. Since herbal medicines are widely available, inexpensive and generally safe, they could represent an ideal approach for preventing the development of AD, in both highly developed and developing countries.

关键词： herbal medicines T cells cytokines permeability barrier dermatitis

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Potential role of noise to improve intracortical microstimulation in tactile neuroprostheses

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Neural Regeneration Research 2021年第8期16卷 1533-1534页

作者： Pedro Mabil Nayeli Huidobro Amira Flores elias Manjarrez Laboratory of Integrative Neurophysiology Instituto de FisiologíaBenemérita Universidad Autónoma de PueblaCPMéxico

The intracortical microstimulation(ICMS) from 40 to 100 μA is useful to elicit tactile sensations,which could be employed in neuroprostheses to control the robotic arms' ***,this electrical current applied for prolonged periods of time could damage the neuronal ***,there is a necessity to create new strategies for the practical use of ICMS in a safe intensity range for potential clinical applications in tetraplegic *** we describe crucial studies supporting the use of electrical and optical noise to guarantee a safe ICMS delivered through brain-machine interface technologies.

关键词： guarantee supporting sensation

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Wild grapevine(Vitis vinifera ***)in the Hyrcanian relict forests of northern Iran:an overview of current taxonomy,ecology and palaeorecords

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Journal of Forestry Research 2018年第6期29卷 1757-1768页

作者： Alireza Naqinezhad elias Ramezani Morteza Djamali Annik Schnitzler Claire Arnold Department of Biology Faculty of Basic SciencesUniversity of MazandaranBabolsarMazandaranIran Department of Forestry Faculty of Natural ResourcesUrmia UniversityUrmiaIran Institut Mediterraneen de Biodiversite et d’Ecologie(IMBE UMR 7263CNRS-Aix Marseille Universite-IRD-Universite d’Avignon)Europole mediterraneen de l'Arboisbatiment VilleminBP8013545 Aix-En-Provence Cedex 04France Laboratoire Interdisciplinaire des Environnements Continentaux LIEC-UMR 7360 CNRSUniversity of LorraineMetzFrance University of Lausanne Unicentre1015 LausanneSwitzerland

Due to severe anthropogenic impacts on lowland and submontane zones of the Hyrcanian forests of northern Iran, wild grapevine(Vitis vinifera subsp. sylvestris), a sporadically distributed woody liana, is currently considered an endangered species. Using data from the literature and 34 studied populations, herbarium assessments and nine palynological sites, we provide an overview of its taxonomy,distribution and ecology in the first part of the *** separation of the two subspecies, namely V. sylvestris subsp. anebophylla and V. sylvestris subsp. trichophylla(sensu Flora Iranica), based on their leaf indumentums, could not be confirmed by our examination of herbarium materials and field observations. Indumentum of the leaves is a result of leaf polymorphism in different Vitis specimens and can be strongly influenced by environmental conditions. Vitis vinifera subsp. sylvestris grows in a wide range of habitats including wetlands, seasonal stream sides in closed forests,alluvial beds of large rivers, sand dune shrublands and forested wetlands(alder forests). Parrotia persica and Carpinus betulus were the most frequent host species in the studied populations. In the Hyrcanian region, no pollen record of Vitis older than the Mid-or Late-Holocene has yet been established. Despite the intrinsic problem in pollen identification by normal(i.e., light) microscopy of wild from cultivated grapevines, the significant values and persistent occurrence of Vitis pollen since the Mid-Holocene(before the Bronze Age) in the Hyrcanian pollen records may imply the onset of viticulture in low-to mid-elevation sites in the region. This represents an argument to consider the Hyrcanian region as a possible domestication center for V. ***, the question of wild versus cultivated origin of grapevines in the Hyrcanian pollen records and the possible date of its domestication and/or cultivation will remain open until further palynological studies are undertaken.

关键词： Domestication Grapevine Hyrcanian forests Pollen Vitis

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Life cycle assessment of urban uses of biochar and case study in Uppsala,Sweden

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Biochar 2022年第1期4卷 889-905页

作者： elias S.Azzi Erik Karltun Cecilia Sundberg Department of Sustainable Development Environmental Engineeringand Sciences(SEED)KTH Royal Institute of TechnologyTeknikrigen 10B11428 StockholmSweden Department of Soil and Environment Swedish University of Agricultural Sciences(SLU)UppsalaSweden Department of Energy and Technology Swedish University of Agricultural Sciences(SLU)UppsalaSweden

Biochar is a material derived from biomass pyrolysis that is used in urban *** environmental impacts of new biochar products have however not been ***,the life cycle assessments of 5 biochar products(tree planting,green roofs,landscaping soil,charcrete,and biofilm carrier)were performed for 7 biochar supply-chains in 2 energy *** biochar products were benchmarked against reference products and oxidative use of biochar for steel *** demand was then estimated,using dynamic material flow analysis,for a new city district in Uppsala,*** a decarbonised energy system and with high biochar stability,all biochar products showed better climate performance than the reference products,and most applications outperformed biomass use for decarbonising steel *** climate benefits of using biochar ranged from−1.4 to−0.11 tonne CO_(2)-eq tonne−1 biochar in a decarbonised energy *** other environmental impact categories,biochar products had either higher or lower impacts than the reference products,depending on biochar supply chain and material substituted,with trade-offs between sectors and impact ***,several use-phase effects of biochar were not included in the assessment due to knowledge *** Uppsala’s new district,estimated biochar demand was around 1700 m^(3)year^(−1)during the 25 years of *** 2100,23%of this biochar accumulated in landfill,raising questions about end-of-life management of biochar-containing ***,in a post-fossil economy,biochar can be a carbon dioxide removal technology with benefits,but biochar applications must be designed to maximise co-benefits.

关键词： Biochar Carbon dioxide removal Urban areas Bioeconomy Life cycle assessment Material flow analysis

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Systemic treatment for hepatocellular carcinoma:Still unmet expectations

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World Journal of Hepatology 2017年第2期9卷 80-90页

作者： Dimitrios N Samonakis elias A Kouroumalis Department of Gastroenterology and Hepatology University Hospital of Heraklion71110 CreteGreece

Many patients with hepatocellular carcinoma(HCC) are diagnosed in an advanced stage, so they cannot be offered the option of curative treatments. The results of systemic chemotherapy are unsatisfactory and this has led to molecular targeted *** develops in chronically damaged tissue due to cirrhosis in most patients. Several different cell types and molecules constitute a unique microenvironment in the liver, which has significant implications in tumor development and invasion. This, together with genome instability, contributes to a significant heterogeneity which is further enhanced by the molecular differences of the underlying causes. New classifications based on genetic characteristics of the tissue microenvironment have been proposed and key carcinogenic signaling pathways have been described. Tumor and adjacent tissue profiling seem biologically promising, but have not yet been translated into clinical settings. The encouraging first results with molecular- genetic signatures should be validated and clinically applicable. A more personalized approach to modern management of HCC is urgently needed.

关键词： Systemic Chemotherapy Hepatocellular carcinoma Prognosis

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Therapeutic Benefits of Natural Ingredients for Atopic Dermatitis

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Chinese Journal of Integrative Medicine 2018年第4期24卷 308-314页

作者： George Man HU Li-zhi Peter M elias Mao-qiang Man Dermatology Services Veterans Affairs Medical Center and University of California San Francisco School of Basic Medical Sciences Tianjin Medical University

Although a variety of regimens are available for the treatment of atopic dermatitis（AD）, severe adverse reactions and unpopular costs often limit their usage. In contrast, certain inexpensive, naturally-occurring ingredients are proven effective for AD with fewer side effects. The beneficial effects of these ingredients can be attributed to inhibition of cytokine and chemokine expression, IgE production, inflammatory cell infiltration, histamine release, and/or the enhancement of epidermal permeability barrier function. Since herbal medicines are widely available, inexpensive and generally safe, they could be valuable alternatives for the treatment of AD, particularly for those patients who are not suitable for the utilization of immune modulators. In this review, we summarize the therapeutic benefits of natural ingredients for the treatment of AD and the mechanisms of their actions.

关键词： atopic dermatitis natural ingredients permeability barrier transepidermal water loss inflammation

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The role of an integration identity in the analysis of the Cauchy-Leraytransform

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中国科学：数学 2017年第11期47卷 J0001-J0006页

作者： LANZANI Loredana STEIN elias M. Department of Mathematics Syracuse University Department of Mathematics Princeton University

The purpose of this paper is to complement the results by Lanzani and Stein （2017） by showing thedense definability of the Cauchy-Leray transform for the domains that give the counter-examples of Lanzani andStein （2017）, where LP-boundedness is shown to fail when either the ＂near＂ C2 boundary regularity, or the strongC-linear convexity assumption is dropped.

关键词： Hardy space Cauchy integral Cauchy-Szego projection Lebesgue space pseudoconvex do-main minimal smoothness Leray-Levi measure

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