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Climate Change vs Cultural Heritage: An Adaptation Strategy for the Archaeological Site of Ancient Messene

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American Journal of Climate Change 2023年第3期12卷 456-488页

作者： Vasiliki Pougkakioti Miltiades Lazoglou eleni Maistrou ELLINIKI ETAIRIA-Society for the Environment and Cultural Heritage Athens Greece

This article examines the effects of climate change on archaeological sites, using as a case study the archaeological site of Ancient Messene in Greece, and proposes an integrated adaptation strategy. In order to determine the site’s most significant risks, a climate data analysis was conducted, taking into account three different climate emission scenarios (Representative Concentration Pathways) and two future periods (2031-2060, 2071-2100). The Intergovernmental Panel on Climate Change (IPCC) vulnerability assessment methodology was adopted to assess the vulnerability of the archaeological site to the effects of climate change. This is the first time such a methodology has been followed in Greece. The analysis revealed that the site’s critical hazards are fire, desertification, and flooding. The geographical location of the site in an intensely dry microclimate and the lack of safe and functional electromechanical and road infrastructure increase its vulnerability. The materials of the monuments are indirectly and directly impacted by climate change, whereas the vegetation is negatively impacted by the frequency of extreme events, especially wildfires. Based on the analysis results, a five-axis adaptation strategy was developed.

关键词： Climate Change Cultural Heritage Archaeological Site Vulnerability Resilience Adaptive Capacity Adaptation Strategy

Management and control applications in Agriculture domain via a Future Internet Businessto- Business platform

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Information Processing in Agriculture 2015年第1期2卷 51-63页

作者： Sokratis Barmpounakis Alexandros Kaloxylos Aggelos Groumas Lampros Katsikas Vasileios Sarris Konstantina Dimtsa Fabiana Fournier eleni Antoniou Nancy Alonistioti Sjaak Wolfert Department of Informatics and Telecommunications University of AthensGreece Department of Informatics and Telecommunications University of PeloponneseGreece OPEKEPE Greek Payment Authority of Common Agricultural Policy(C.A.P.)Aid SchemesGreece IBM-Research Haifa Israel Logistics Decision and Information Sciences GroupWageningen UniversityNetherlands

The Agriculture business domain,as a vital part of the overall supply chain,is expected to highly evolve in the upcoming years via the developments,which are taking place on the side of the Future *** paper presents a novel Business-to-Business collaboration platform from the agri-food sector perspective,which aims to facilitate the collaboration of numerous stakeholders belonging to associated business domains,in an effective and flexible *** contemporary B2B collaboration schemes already place the requirements for swift deployment of cloud applications,capable of both integrating diverse legacy systems,as well as developing in a rapid way new services and systems,which will be able to instantly communicate and provide complete,"farm-to-fork"solutions for farmers,agrifood and logistics service providers,ICT companies,end-product producers,*** this end,this conceptual paper describes how these requirements are addressed via the FIspace B2B platform,focusing on the Greenhouse Management&Control scenarios.

关键词： Future Internet FI-WARE Generic Enablers B2B platform Agriculture Internet of Things

Circulating microRNAs as biomarkers for diabetic neuropathy: A novel approach

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World Journal of Experimental Medicine 2018年第3期8卷 18-23页

作者： eleni Xourgia Athanasia Papazafiropoulou Andreas Melidonis 1st Department of InternalMedicine and Diabetes Center Tzaneio General Hospital of Piraeus

Oxidative stress stemming from tissue exposure to constant hyperglycemia is one of the major pathogenetic pathways of diabetic macro-and microvascular complications. Diabetic polyneuropathy, commonly manifesting as distal,symmetrical sensorimotor polyneuropathy, is characterized by progressive severity of symptoms, with rates analogous to the quality of glycemic control achieved by the patients and physicians. Palliative care with analgesics and aggressive glycemic control often improve quality of life in the absence of causative treatment. Currently, there is a growing body of evidence indicating the role of microRNAs in the pathogenesis of diabetic complications, with emphasis on diabetic nephropathy and neuropathy. Therefore, in this review, we aim to explore the role of microRNAs and their polymorphisms in the pathophysiology of diabetic polyneuropathy, as well as, the possibility of novel diagnostic and therapeutic applications by epigenetic profiling and manipulation.

关键词： Diabetic neuropathy Type 2 diabetes mellitus Type 1 diabetes mellitus Epigenetic MicroRNAs

COVID-19 and liver injury in individuals with obesity

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World Journal of Gastroenterology 2023年第6期29卷 908-916页

作者： Ioannis G Lempesis eleni Karlafti Petros Papalexis George Fotakopoulos Kyriakos Tarantinos Vasileios Lekakis Stavros P Papadakos Evangelos Cholongitas Vasiliki E Georgakopoulou Institute of Metabolism and Systems Research University of BirminghamBirminghamB152TTUnited Kingdom Department of Human Biology NUTRIM School of Nutrition and Translational Research in MetabolismMaastricht University Medical CentreMaastricht 6166200Netherlands Department of Emergency AHEPA University HospitalAristotle University of ThessalonikiThessaloniki 54621Greece Unit of Endocrinology First Department of Internal MedicineLaiko General HospitalNational and Kapodistrian University of AthensAthens 11527Greece Department of Biomedical Sciences University of West AtticaAthens 12243Greece Department of Neurosurgery General University Hospital of LarisaLarisa 41221Greece First Pulmonology Department Sismanogleio HospitalAthens 15126Greece Department of Gastroenterology Laiko General HospitalNational and Kapodistrian University of AthensAthens 11527Greece First Department of Internal Medicine Laiko General HospitalMedical SchoolNational and Kapodistrian University of AthensAthens 11527Greece Department of Infectious Diseases-COVID-19 Unit Laiko General HospitalAthens 11527Greece

Coronavirus disease 2019 is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 that manifests as a variety of clinical manifestations,including liver damage commonly detected by a hepatocellular pattern from liver function *** injury is associated with a worse prognosis *** associated with the severity of the disease include obesity and cardiometabolic comorbidities,which are also associated with nonalcoholic fatty liver disease(NAFLD).The presence of NAFLD,similarly to obesity,is associated with an unfavourable impact on the coronavirus disease 2019 *** with these conditions could present with liver damage and elevated liver function tests due to direct viral cytotoxicity,systemic inflammation,ischemic or hypoxic liver damage or drug side ***,liver damage in the setting of NAFLD could also be attributed to a pre-existing chronic low-grade inflammation associated with surplus and dysfunctional adipose tissue in these *** we investigate the hypothesis that a pre-existing inflammatory status is exacerbated after severe acute respiratory syndrome coronavirus 2 infection,which embodies a second hit to the underestimated liver damage.

关键词： COVID-19 SARS-CoV-2 Non-alcoholic fatty liver disease Obesity Inflammation Liver Adipose tissue

Adrestus:Secure,scalable blockchain technology in a decentralized ledger via zones

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Blockchain(Research and Applications) 2022年第4期3卷 56-80页

作者： Panagiotis Drakatos eleni Koutrouli Aphrodite Tsalgatidou Department of Informatics and Telecommunications National and Kapodistrian University of AthensPanepistimiopolis15784IlisiaAthensGreece

Nowadays,an increasing number of blockchain architectures provide well-promising protocols for pseudonymous online payments via proposed *** of them suffer from a number of extensibility and scalability issues,as their capacity regarding the number of transactions they are capable of processing per second is *** is also a challenge for this kind of *** paper presents the design and implementation of the Adrestus system,a blockchain-based transaction system with a novel consensus mechanism that is able to tolerate Byzantine faults and is designed to scale without compromising system *** of the main components of the Adrestus design is a consistent hashing mechanism for the efficient assignment of transactions on parallel regions,called zones,and for solving load balancing *** claim that the Adrestus blockchain system scales linearly without compromising system security and achieves its goals without introducing the unnecessary overhead and by eliminating energy and computational *** theoretical simulations and results reflect that Adrestus exceeds the average throughput of the most well-known cryptocurrencies like Bitcoin,and thus,it achieves a higher *** this paper,we present this proposed approach along with simulation results and examine the conditions for the proposed fault-tolerant system to meet safety and liveness.

关键词： Blockchain Consensus protocol Byzantine fault tolerance Scalability Distributed systems Aggregated signatures

The lingualized occlusion of complete denture

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国际口腔医学杂志 2008年第5期35卷 499-501页

作者：任卫红 eleni Roumanas Dept.of Prosthodontics Beijing Stomatology HospitalCapital Medical University Removable Prosthodontics University of California Los Angles School of Dentistry

This article reviews the literatures dealing with the lingualized occlusion of complete denture including the origin,development and *** occlusion is a valuable concept because many advantages of anatomic and nonanato... 详细信息

关键词：假牙口腔医学牙齿保护方法

Volumetric assessment of hepatic grafts using a light detection and ranging system for 3D scanning:Preliminary data

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World Journal of Hepatology 2022年第7期14卷 1504-1511页

作者： Georgios Katsanos Konstantina-eleni Karakasi Ion-Anastasios Karolos Athanasios Kofinas Nikolaos Antoniadis Vassilios Tsioukas Georgios Tsoulfas Department of Transplantation Medical SchoolAristotle University of ThessalonikiHippokration General HospitalThessaloniki 54642Greece Department of Rural and Surveying Engineering Aristotle University of ThessalonikiThessaloniki 54642Greece

BACKGROUND Liver transplantation has evolved into a safe life-saving operation and remains the golden standard in the treatment of end stage liver *** main limiting factor in the application of liver transplantation is graft *** strategies have been developed in order to alleviate graft shortage,such as living donor partial liver transplantation and split liver transplantation for adult and pediatric *** these strategies,liver volume assessment is of paramount importance,as size mismatch can have severe consequences in the success of liver *** To evaluate the safety,feasibility,and accuracy of light detection and ranging(LIDAR)3D photography in the prediction of whole liver graft volume and *** Seven liver grafts procured for orthotopic liver transplantation from brain deceased donors were prospectively measured with an LIDAR handheld camera and their mass was calculated and compared to their actual *** The mean error of all measurements was 17.03 g(range 3.56-59.33 g).Statistical analysis of the data yielded a Pearson correlation coefficient index of 0.9968,indicating a strong correlation between the values and a Student’s t-test P value of *** accuracy of the measurements was calculated at 97.88%.CONCLUSION Our preliminary data indicate that LIDAR scanning of liver grafts is a safe,cost-effective,and feasible method of ex vivo determination of whole liver volume and *** data are needed to determine the precision and accuracy of this method.

关键词： Light detection and ranging Graft volume 3dscan Ex vivo volumetry Liver grafts

Management Development Trends of Nowadays in Albania

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Chinese Business Review 2011年第7期10卷 559-568页

作者： Sonela Stillo eleni Vangjeli Enton Stillo University ＂Fan S.Noli＂ Korca Albania American University ＂San Clement＂ Ohrid Macedonia

Albanian business environment is defined by complexity, dynamism, uncertainty. In Albania, there are small and medium enterprises （businesses）. Although we have a high degree of business bankrupt, many businesses are reinforcing their competitive positions in market. In these conditions, a new appropriate organizational structure often plays a crucial role in managing the challenges. While the finn grows, at the same time grows the need for organization, involvement and leadership. In today＇s changing times, effective leadership is a key component of organizational success. Even if management is the key of operation and the standard operating procedures, our study shows that the manager always need leader＇s power. In today＇s global marketplace, organizations that strategically focus on building leadership capacity for the future will reap the benefits in the years to come. New trends in business development, of course have increased requirements for local managers. The organizations are under pressure to show return on investment for training and development. Although positive trends, problems which management is faced are more challenging than the degree of preparation and performance that they offer, so their qualitative qualification remains the continuous preoccupation as the role of our school is in this direction. From this point of view, education in distance can be considered as complementary approach and in some conditions as a worthy replacement of direct education, which still dominates educative systems in Albania.

关键词： management structure leadership training public private business

Hematopoietic stem cell mobilization strategies to support high-dose chemotherapy:A focus on relapsed/refractory germ cell tumors

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World Journal of Clinical Oncology 2021年第9期12卷 746-766页

作者： eleni Porfyriou Sylvia Letsa Christos Kosmas Department of Medical Oncology and Hematopoietic Cell Transplant Unit “Metaxa”Cancer HospitalPiraeus 18537Greece

High-dose chemotherapy(HDCT)with autologous hematopoietic stem cell transplantation has been explored and has played an important role in the management of patients with high-risk germ cell tumors(GCTs)who failed to be cured by conventional *** stem cells(HSCs)collected from the peripheral blood,after appropriate pharmacologic mobilization,have largely replaced bone marrow as the principal source of HSCs in *** it is currently common practice to perform tandem or multiple sequential cycles of HDCT,it is anticipated that collection of large numbers of HSCs from the peripheral blood is a prerequisite for the success of the ***,the CD34+cell dose/kg of body weight infused after HDCT has proven to be a major determinant of hematopoietic engraftment,with patients who receive>2×106 CD34+cells/kg having consistent,rapid,and sustained hematopoietic ***,many patients with relapsed/refractory GCTs have been exposed to multiple cycles of myelosuppressive chemotherapy,which compromises the efficacy of HSC mobilization with granulocyte colony-stimulating factor with or without ***,alternative strategies that use novel agents in combination with traditional mobilizing regimens are ***,after an overview of the mechanisms of HSCs mobilization,we review the existing literature regarding studies reporting various HSC mobilization approaches in patients with relapsed/refractory GCTs,and finally report newer experimental mobilization strategies employing novel agents that have been applied in other hematologic or solid malignancies.

关键词： Hematopoietic stem cells Germ cell tumors Hematopoietic stem cell transplantation Granulocyte colony-stimulating factor Plerixafor