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Translation and validation of the Greek chronic liver disease questionnaire

World Journal of Gastroenterology 2010年第46期16卷 5838-5844页

作者： Zoi kollia Evridiki Patelarou Victoria Vivilaki eleni kollia Florentia Kefou Ioannis Elefsiniotis Spyros P Dourakis Hero Brokalaki Department of Internal Medicine Faculty of NursingUniversity of Athens Department of Nursing University Hospital of Heraklion Department of Midwifery SEYPTEI of Athens Department of Nursing Hippokration General Hospital of Athens Department of Nursing Naval Hospital of Athens 2nd Department of Internal Medicine Medical SchoolUniversity of Athens

AIM:To translate into Greek and validate the chronic liver disease questionnaire (CLDQ).METHODS:Two hundred and six consecutive adult patients with the diagnosis of a chronic liver disease from 2 general hospitals in Athens were enrolled in the study from May to September *** order to assess their quality of life (QOL) the CLDQ was *** instrument was translated from English,back translated and reviewed in focus groups within the framework of a large multicenter *** measurements that were performed included:2 independent sample t tests,oneway analysis of variance,reliability coefficients,explanatory factor analysis using a varimax rotation and the principal components ***:One hundred and twenty five (61%) patients were men,half were aged 40-59 years and > 33% were > 60 years *** the patients,48 (23%) were hospitalized and 97 (47%) were cirrhotic according to the Child-Pugh *** internal consistency of the Greek CLDQ version using Cronbach's alpha coefficient was found to be *** factor analysis identified 7 domains accounting for 65% of the variance of CLDQ items and only partially overlapping with those found in the original *** area under the receiver operating characteristics curve was calculated at 0.813 and the logistic estimate for the threshold score of 167.50 provided a sensitivity of 74.3% and a specificity of 71.6% for the ***:Our data confirmed the validity of the Greek version of the CLDQ in identifying the QOL among patients with chronic liver disease.

关键词： Chronic disease Questionnaires Validation Quality of life Liver cirrhosis

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