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Helicobacter pylori in gastric cancer: Features of infection and their correlations with long-term results of treatment

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World Journal of Gastroenterology 2021年第37期27卷 6290-6305页

作者： Marina A Senchukova Olesya Tomchuk elena i shurygina Department of Oncology Orenburg State Medical UniversityOrenburg 460000Russia Department of Histology CytologyEmbryologyOrenburg State Medical UniversityOrenburg 460000Russia Department of Pathology Orenburg State Medical UniversityOrenburg 460000Russia

BACKGROUND Helicobacter pylori(***)is a spiral-shaped bacterium responsible for the development of chronic gastritis,gastric ulcer,gastric cancer(GC),and MALTlymphoma of the *** can be present in the gastric mucosa(GM)in both spiral and coccoid ***,it is not known whether the severity of GM contamination by various vegetative forms of *** is associated with clinical and morphological characteristics and long-term results of GC *** To establish the features of *** infection in patients with GC and their correlations with clinical and morphological characteristics of diseases and long-term results of *** Of 109 patients with GC were included in a prospective cohort *** in the GM and tumor was determined by rapid urease test and by immunohistochemically using the antibody to *** results obtained were compared with the clinical and morphological characteristics and prognosis of *** analysis was performed using the Statistica 10.0 *** *** was detected in the adjacent to the tumor GM in 84.5%of cases,of which a high degree of contamination was noted in 50.4%of the *** forms of *** were detected in 93.4%of infected patients,and only coccoid-in 68.9%.it was found that a high degree of GM contamination by the coccoid forms of *** was observed significantly more often in diffuse type of GC(P=0.024),in poorly differentiated GC(P=0.011),in stage T3-4(P=0.04)and in N1(P=0.011).in cases of moderate and marked concentrations of *** in GM,a decrease in 10-year relapse free and overall survival from 55.6%to 26.3%was observed(P=0.02 and P=0.07,respectively).The relationship between the severity of the GM contamination by the spiral-shaped forms of *** and the clinical and morphological characteristics and prognosis of GC was not *** The data obtained indicates that *** may be associated not only with induction but also wit

关键词： Gastric cancer Helicobacter pylori Coccoid and spiral forms of bacteria Rapid urease test Relapse free survival Overall survival

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Approach to the Theoretical Strength of Ti—Ni—Cu Alloy Nanocrystals by Grain Boundary Design

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Journal of Materials Science & Technology 2015年第1期31卷 91-96页

作者： Alexandr M.Glezer Nadezhda A.shurygina elena N.Blinova inga E.Permyakova Sergey A.Firstov Bardin Central Research institute for the iron and Steel industry Vtoraya Baumanskaya ul.9/23Moscow 105005Russia Moscow State University of instrumental Engineering and information Science(MGUPi) Moscow 107996Russia National University of Science and Technology(MiSiS) Moscow 119049Russia Frantsevich institute of Materials Science Problems National Academy of Sciences of Ukraineul.Krzhizhanovskogo 3Kiev03680Ukraine

The grain boundary design was used to introduce boride Ti2B and TiB2nanoparticles of 5 nm in size into grain boundaries of nanocrystalline *** a result,the maximum normalized microhardness was increased by 20%and the theoretical limit of hardness is substantially *** is proposed that boride nanoparticles suppressed low-temperature grain-boundary sliding and,therefore,shifted the range of the anomalous behavior of Hall-Petch relation toward smaller sizes of the Ti-Ni-Cu nanocrystals.

关键词： Electron microscopy Microhardness Nanocrystal Nano

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