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Dexmedetomidine Causes Increased Hypotension in Older Adults When Used for Cataract Surgery Compared to Propofol

Open Journal of Anesthesiology 2013年第4期3卷 237-242页

作者： Irwin Gratz Smith Jean Edward Deal Erin Pukenas elaine allen Marc C. Torjman Department of Anesthesiology Cooper Medical School at Rowan University Cooper University Hospital Camden USA Department of Anesthesiology Cooper Medical School at Rowan University Cooper University Hospital Camden USA Department of Epidemiology & Biostatistics University of California at San Francisco San Francisco USA.

Purpose: This study evaluated the hemodynamic effects, suitability and safety of dexmedetomidine (DEX) compared with propofol (PRO) in older adults having outpatient cataract surgery under monitored anesthesia care. The patients, surgeon and the anesthesia staff evaluated satisfaction for both ***: This prospective, single blind, randomized study was conducted using forty-seven patients ≥55 years old undergoing cataract surgery. The two patient groups received either i.v. dexmedetomidine 1 μg/kg over 10 min;followed by maintenance i.v. infusion at 0.2 -0.7 μg/kg/hr (DEX group, N = 24), or propofol infused between 25 -120 μg/kg/min (PRO group, N = 23). Both agents were titrated to patient comfort. Results: Patients’ mean arterial pressures (SEM) at baseline were 104.7 (2.6) and 107.5 (2.7) mmHg for the DEX and PRO groups, respectively (p = 0.45). At discharge the pressures were 78.1 (2.5) and 98.1 (2.6) mmHg in DEX and PRO groups, respectively (p 0.05). Patients’ heart rates (SEM) at baseline were 74.8 (3.0) for the DEX group and 73.2 (2.8) bpm for the PRO groups (p = 0.71). At the time of discharge following surgery, the mean heart rate for the DEX group was 61.5 (2.2) bpm vs. 69.1 (2.3) bpm (p 0.05) for the PRO group. Three patients in the DEX group developed complications precluding discharge or requiring readmission while none of the patience in the PRO group had complications (p = 0.08). Patient and surgeon satisfaction scores were similar between the groups. Conclusion: Dexmedetomidine is a less suitable sedative compared with propofol use in older patients undergoing cataract surgery due to the decrease in hemodynamic parameters and noted increases in complication rates.

关键词： Cataract Surgery Dexmedetomidine Monitored Anesthesia Care Propofol

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打造梦幻棒球的梦之队

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中国认证认可 2007年第12期 42-45页

作者：伊菜恩·艾伦（I．elaine allen）基里尔·库斯托夫（Kirill Kustov）乔治·菜克（George Recck）李伟（译）

梦幻棒球已成为希望通过相互比赛，展示其棒球水平的体育迷们所流行的社交活动。梦幻棒球有助于培养在规划和研究时注重细节的习惯，以期在比赛中胜过对手；同时它也推动了那些有助于球队老板用来确定上场人选的运动数据分析工具在市场... 详细信息

梦幻棒球已成为希望通过相互比赛，展示其棒球水平的体育迷们所流行的社交活动。梦幻棒球有助于培养在规划和研究时注重细节的习惯，以期在比赛中胜过对手；同时它也推动了那些有助于球队老板用来确定上场人选的运动数据分析工具在市场上的逐渐兴起。

关键词：棒球数据分析工具社交活动比赛水

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Trees as hotspots:Using forests,trees,and agroforestry to foster diverse sustainable landscapes

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Circular Agricultural Systems 2022年第1期2卷 30-37页

作者： Vincent Gitz Jianchu Xu Yuanchang Lu elaine Springgay Illias Animon Razan Khalifa Al Mubarak Robert Nasi Tony Simons Ranjit Barthakur Ren Wang Jianrong Su Fergus Sinclair Eduardo Somarriba Dossa G.O.Gbadamassi Ramni Jamnadass Christopher JKettle Dengpan Bu Anja Gassner Yves Laumonier Mi Zhou Himlal Baral Fangyuan Hua Peter AMinang Yufu Guo Michael allen Brady Yanxia Li Peter Mortimer Bin Yang Heng Gui Fiona Worthy Deli Zhai Huafang Chen Huili Li Yufang Su Alexandre Meybeck Fabio Ricci CIFOR-ICRAF Bogor 16115Indonesia Center for Mountain Futures Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China CIFOR-ICRAF China Program World AgroforestryKunming 650201China State Key Laboratory of Animal Nutrition Institute of Animal SciencesChinese Academy of Agricultural SciencesBeijing 100081China Research Institute of Forest Resource Information Techniques Chinese Academy of ForestryBeijing 100091China Food and Agriculture Organization of the United Nations(FAO) Rome 00153Italy Food and Agriculture Organization of the United Nations(FAO) Bangkok 10200Thailand Mohamed bin Zayed Species Conservation Fund Abu Dhabi 131112United Arab Emirates Balipara Foundation GuwahatiAssam 781024India China National Gene Bank Shenzhen 518083China Research Institute of Resource Insects Chinese Academy of ForestryKunming 650233China World Agroforestry Centre(ICRAF) United Nations AvenueGigiriP.O.Box 30677-00100NairobiKenya CATIE Turrialba 30501Costa Rica Xishuangbanna Tropical Botanical Garden Chinese Academy of SciencesMengla 666303China Bioversity International Rome 00153Italy Global Landscapes Forum CIFOR gmbHCharles-de-Gaulle-Straße 553113 BonnGermany Institute of American and Oceania Study Chinese Academy of International Trade and Economic CooperationMinistry of CommerceBeijingChina Institute of Ecology Peking UniversityBeijing 100871China National Forestry and Grassland Administration Beijing 100714China International Network for Bamboo and Rattan(INBAR) Beijing 100102China Yunnan University Kunming 650500China Editorial Office of Biological Science Institute of BotanyChinese Academy SciencesBeijing 100093China

Forests,trees,and agroforestry(FTA)are ecosystem *** exemplify the contributions of biodiversity to sustainable and resilient landscapes,green circular economy and to sustainable agriculture and food systems for healthy ***,most research on these topics have been performed separately and lack *** International FTA-Kunming Conference'Forests,trees and agroforestry for diverse sustainable landscapes'22nd–24th June 2021,focused on these contributions,brought together scientists NGOs,and policy makers to further the understanding of tree diversity;provided a communication platform for scientists to share their research results;evaluated the role of tree diversity in agroecology and circular agriculture;assessed benefits of landscape restoration;and explored applied research in mountain ecosystems and food *** goals were to gather evidence that ground the design of solutions that can contribute to the implementation of the post 2020 Global Biodiversity Framework and towards the UN Food Systems Summit,and the overall implementation of the *** paper summarizes the outcomes of the international FTA Conference in Kunming 2021 and points out the highlights of research involved in six major themes.

关键词： landscape sustainable diverse

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围手术期输注红细胞可降低心脏手术术后远期存活率

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麻醉与镇痛 2010年第5期6卷 81-88页

作者： Stephen D. Surgenor, MD Robert S. Kramer, MD elaine M. Olmstead, BA Cathy S. Ross, MS Frank W. Sellke, MD Donald S. Likosky, PhD Charles A. S. Martin, MBBS Robert E. Helm, Jr., mD Bruce J. Leavitt, MD Jeremy R. Morton, MD David C. Charlesworth, MD Robert A. Clough, MD Felix Hernandez, MD Carmine Frumiento, MD Arnold Benak, CCP Christian DioData, CCP Gerald T. O'Connor, PhD, DSc 周全红(译) 江伟(校) Dartmouth-Hitchcock Medical Center Lebanon New Hampshire Maine Medical Center Portland Maine Dartmouth Medical School Hanover New Hampshire Beth Israel Deaconess Medical Center Boston Massachusetts Portsmouth Regional Hospital Portsmouth New Hampshire Fletcher allen Health Care Burlington Vermont New England Heart Institute Catholic Medical Center Manchester New Hampshire Eastern Maine Medical Center Bangor Maine Central Maine Medical Center Lewiston Maine Concord Hospital Concord New Hampshire The Dartmouth Institute for Health Policy and Clinical Practice Dartmouth College Lebanon New Hampshire 不详

背景输注红细胞（RBC）与心脏手术后死亡率升高有关。我们分析了在住院期间接受了1或2个单位RBC输注的心脏手术患者的长期生存情况。方法将2001年至2004年期间9079例，在新英格兰北部地区8个医疗中心中接受了冠状动脉旁路移植术、瓣膜... 详细信息

背景输注红细胞（RBC）与心脏手术后死亡率升高有关。我们分析了在住院期间接受了1或2个单位RBC输注的心脏手术患者的长期生存情况。方法将2001年至2004年期间9079例，在新英格兰北部地区8个医疗中心中接受了冠状动脉旁路移植术、瓣膜手术或同时进行了冠状动脉旁路移植术和瓣膜手术的患者纳入本研究。研究将纳入地区与2006年6月30日社会保障署死亡档案确定的死亡率进行概率性配对。调整的风险比采用Cox比例风险和倾向评分法进行计算。结果36％的患者（n=3254）接受过1或2个单位的RBC。43％的RBCs是在手术中被输注的，分别有56％和1％的RBCs是在手术后和手术前输注的。输血的患者更可能是贫血、高龄、体表面积小、女性和同时患多种疾病的患者。那些在心脏手术住院期间接受了1或2个单位RBCs的患者的存活率显著低于未接受过RBCs的患者（P〈0．001）。调整了患者和疾病特征之后，接受1或2个单位RBCs仍使远期死亡风险提高16％（调整的风险比=1．16，95％CI：1．01—1．34，P=0．035）。结论输注1或2个单位的RBCs可使心脏手术术后存活率降低的风险提高16％。

关键词：术后死亡率心脏手术远期存活率红细胞输注围手术期冠状动脉旁路移植术 RBCs

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