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Complement-dependent neuroinflammation in spinal cord injury:from pathology to therapeutic implications

Neural Regeneration Research 2025年第5期20卷 1324-1335页

作者： Hassan Saad Bachar el Baba Ali Tfaily Firas Kobeissy Juanmarco Gutierrez Gonzalez Daniel Refai Gerald R.Rodts Christian Mustroph David Gimbel Jonathan Grossberg Daniel l.Barrow Matthew F.Gary Ali M.Alawieh Department of Neurosurgery Emory University School of MedicineAtlantaGAUSA Department of Neurology Yale UniversityNew HavenCTUSA Center for Neurotrauma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spinal cord injury remains a major cause of disability in young adults,and beyond acute decompression and rehabilitation,there are no pharmacological treatments to limit the progression of injury and optimize recovery in this *** the thorough investigation of the complement system in triggering and propagating cerebral neuroinflammation,a similar role for complement in spinal neuroinflammation is a focus of ongoing *** this work,we survey the current literature investigating the role of complement in spinal cord injury including the sources of complement proteins,triggers of complement activation,and role of effector functions in the *** study relevant data demonstrating the different triggers of complement activation after spinal cord injury including direct binding to cellular debris,and or activation via antibody binding to damage-associated molecular *** effector functions of complement have been implicated in spinal cord injury,and we critically evaluate recent studies on the dual role of complement anaphylatoxins in spinal cord injury while emphasizing the lack of pathophysiological understanding of the role of opsonins in spinal cord *** this pathophysiological review,we systematically review the different translational approaches used in preclinical models of spinal cord injury and discuss the challenges for future translation into human *** review emphasizes the need for future studies to dissect the roles of different complement pathways in the pathology of spinal cord injury,to evaluate the phases of involvement of opsonins and anaphylatoxins,and to study the role of complement in white matter degeneration and regeneration using translational strategies to supplement genetic models.

关键词： complement neuroinflammation neuroplasticity regeneration spinal cord injury targeted therapy

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Disruption of biofilms from sewage pipes under physical and chemical conditioning

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Journal of Environmental Sciences 2009年第1期21卷 120-126页

作者： Charbel Mahfoud Antoine el Samrani Rita Mouawad Walid Hleihel Rim el Khatib Bruno S. lartiges nam Ouani Holy Spirit University of Kaslik(USEK) Faculty of Sciences and Computer Engineering Department of Chemistry and Life SciencesWater and Environment Laboratory. P.B. 446JouniehLebanon nancy University LEM-ENSG/INPL-CNRSPole de l'Eau15Avenue du CharmoisBP 40-F-54501 Vandoeuvre CedexFrance

Biofilms grown inside two sewage collecting pipes located in industrial and residential areas are studied. Bacterial biomass inside three layers of biofilms was evaluated. Biofilm cohesion under different mixing rate and ionic strength was also investigated. Effects of physical and chemical parameters in the biofilms were evaluated by monitoring turbidity, chemical and biochemical oxygen demands. Extracted organic matter from biofilms was partitioned to polar, aromatic and saturated fractions using activated silica column chromatography. Results revealed that bacterial biomass growth depending on biofilm thickness and stratification. The most loaded stratum in bacteria/biomass was the sewage-biofilm interface stratum that represented 51% of the total bacteria/biomass. Stirring rate and ionic strength of mono- and bivalent salts showed a major influence in biofilm disruption. The stirring time enhanced the exchange dynamic and matter capture between biofilm fragments at the critical stirring rate 90 r/min. Sodium chloride showed the dispersing effect on biofilms in suspension, and decreased the BOD5 （biochemical oxygen demand） beyond the physiological salt concentration.

关键词： biofilms, biochemical oxygen demand (BODs) chemical oxygen demand (COD) biomass ionic strength

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Cooperative game theoretic load balancing scheme with admission control in IEEE 802.11 WlANs

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Journal of Systems Engineering and electronics 2009年第6期20卷 1361-1365页

作者： lü na Zhang Yuetong Zhang Guopeng The Telecommunication Engineering Inst. Air Force Engineering Univ. Xi'an 710077 P. R. China State Key lab. of Integrated Service Networks Xidian Univ. Xi'an 710071 P. R. China

A load-balancing scheme for IEEE 802.11 WlANs based on cooperative game theory is presented.A coalition among the access points（APs） with overlapping coverage is formed to share the network load through a ***, the candidate APs submit their load-competing strategies（i.e., the amount of user traffic they can admit in an AC/game period） to the control ***, the control AP solves the game by the method of shapley value, which is the maximum traffic allocated to each AP in an AC/game ***, the game is repeated periodically to distribute the traffic load among the *** results show that the proposed game can balance the network load effectively compared with the IEEE 802.11 standard balancing solution.

关键词： IEEE 802.11 DCF game theory load-balancing.

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Nonaqueous potassium-ion full-cells:Mapping the progress and identifying missing puzzle pieces

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Journal of Energy Chemistry 2024年第6期93卷 384-399,I0010页

作者： Badre larhrib louiza larbi lénaïc Madec Universite de Pau et des Pays de l’Adour E2S UPPACNRSIPREMPauFrance Universitéde Haute-Alsace Institut de Science des Matériaux de Mulhouse(IS2M)CNRS UMR 7361F-68100 MulhouseFrance Universitéde Strasbourg F-67081 StrasbourgFrance Réseau sur le Stockage electrochimique de l’Energie CNRS FR3459AmiensFrance Institut des Matériaux Jean Rouxel(IMN) CNRS UMR 6502Univ.Nantes44322 Cedex 3 NantesFrance

This review addresses the growing interest for potassium-ion full-cells(KIFCs)in view of the transition from potassium-ion half-cells(KIHCs)toward commercial K-ion batteries(KIBs).It focuses on the key parameters of KIFCs such as the electrode/electrolyte interfaces challenge,major barriers,and recent advancements in *** strategies for enhancing KIFC performance,including interfaces co ntrol,electrolyte optimization,electrodes capacity ratio,electrode material screening and electrode design,are *** review highlights the need to evaluate KIBs in full-cell configurations as half-cell results are strongly impacted by the K metal *** also emphasizes the importance of understanding solid electrolyte interphase(SEI)formation in KIFCs and explores promising nonaqueous as well as quasiand all-solid-state electrolytes *** review thus paves the way for practical,cost-effective,and scalable KIBs as energy storage systems by offering insights and guidance for future research.

关键词： K-ion full-cells Potassium-ion batteries Cross-talk Solid-state batteries Potassium reactivity electrolyte design electrode design

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Enhancing optical absorption in visible light of ZnO co-doped with europium and promethium by first-principles study through modified Becke and Johnson potential scheme

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Journal of Rare Earths 2019年第4期37卷 416-421页

作者： A.G.el Hachimi M.l.Ould NE A.el Yousfi A.Benyoussef A.el Kenz laboratory of Condensed Matter and Interdisciplinary Sciences (laMCScI) Associé Au CNRST (URAC 12) Département de Physique B.P.1014 Faculté des SciencesUniversité Mohammed V Hassan Ⅱ Academy of Science and Technology

By using first-principles calculations we studied the electronic, optical and magnetic properties of ZnO co-doped with Eu and Pm. In this calculation, we used Wien2 k code based on full potential linearized augmented plane waves(FP-lAPW) method with the modified Becke-Johnson(mBJ) approximation. This correction gives good band gap compared to experimental band gap. The introduction of Eu and Pm codoping leads to an increase in the band gap. electrons can transit easily from the valence band to the conduction band, which results in an enhancement of visible light absorption in a wider absorption range. Absorption spectra reach a high value in visible and infrared light regions. With the significance of the obtained results, the studied compounds may potentially find spintronic and optoelectronic applications.

关键词： Zinc oxide Rare earth Density functional theory Modified Becke-Johnson Magnetic properties Spintronics

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Approach for electrodynamic force for compensation in low voltage circuit breaker WP 630-1.2 type

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第3期8卷 393-396页

作者： lU na XU l.J Miedzifiski B Automation School Beijing University of Posts and Telecommunications Beijing 100876 China electrical Power Engineering Institute Wroclaw University of Technology Wroclaw Poland

Undesirable repulsive force between contact members due to both a current path shrink near a real contact area and/or so-called pinch effect is particularly onerous for power switch applications, and results in either contact floating or bouncing which are associated with an electric arc following contact welding. This problem is of great importance for any circuit breaker especially for compact low voltage vacuum circuit breakers. To avoid contact floating at closure and during any inrush current under short circuit conditions, the electrodynamic repulsive force can be employed successfully if we use a special compensation system flexibly combined with the contact itself. However to select and design the compensation system properly, its efficiency has to be known. This paper presents an approach to obtain the electrodynamic force value depending on different shaped (rectangular, square, circle and arch) copper plates used in the compensator by using ANSYS for current values 40 kA RMS. Curve-fitting was done according to the calculating results, the optimization designing of compensation unit is based on them.

关键词： Compensation. electrodynamic force. FEM (Finite element Method)

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On the Estimation of Solutions for Some linear Systems of Differential Equations

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Acta Mathematica Sinica,English Series 1998年第1期14卷 41-46页

作者： l. R. Awad E. M. el-Kholy Sh. el-Bendary Universitat Hamburg Institut fur Angewandte Mathematik Bundesstraβe 55 20146 Hamburg Germany

In this paper we estimate the solutions of homogeneous linear system of differential equations with unbounded coefficients on the real line R. We also give a necessary and sufficient condition in order that the linear... 详细信息

关键词： Homogeneous linear Unbounded coefficient

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Ammonium-dependent regulation of aerobic methane-consuming bacteria in landfill cover soil by leachate irrigation

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Journal of Environmental Sciences 2012年第4期24卷 711-719页

作者： Fan lü Pinjing He Min Guo na Yang liming Shao State Key laboratory of Pollution Control and Resources Reuse College of Environmental Science and EngineeringTongji UniversityShanghai 200092China

The impacts of landfill leachate irrigation on methane oxidation activities and methane-consuming bacteria populations were studied by incubation of landfill cover soils with leachate and （NH4）2SO4 solutiort at different ammonium concentrations. The community structures and abundances of methane-oxidizing bacteria （MOB） and ammonia-oxidizing bacteria （AOB） were examined by PCR- DGGE and real-time PCR. Compared with the pure （NH4）2SO4 solution, leachate addition was found to have a positive effect on methane oxidation activity. In terms of the irrigation amount, ammonium in leachate was responsible for the actual inhibition of leachate. The extent of inhibitory effect mainly depended on its ammonium concentration. The suppression of the predominant methane- consuming bacteria, type I MOB, was responsible for the decreased methane oxidation activity by ammonium inhibition. Methane- consuming bacteria responded diversely in abundance to ammonium. The abundance of type I MOB decreased by fivefold; type II MOB showed stimulation response of fivefold magnification upon the first addition but lessened to be lower than the original level after the second addition; the amount of AOB was stimulated to increase for 20-30 times gradually. Accumulated nitrate from nitrification strengthened the ammonium inhibition on type I and type II MOB, as a result, repetitive irrigation was unfavorable for methane oxidation.

关键词： greenhouse gas emission landfill leachate methane oxidation methane-oxidizing bacteria (MOB) ammonia-oxidizing bacteria (AOB)

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Excimer laser 6^(th)generation:state of the art and refractive surgical outcomes

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Eye and Vision 2015年第1期2卷 44-52页

作者： Mohamed el Bahrawy Jorge l Alió Vissum Corporación Alicante AlicanteSpain Division of Ophthalmology Universidad Miguel HernándezAlicanteSpain Clinical research fellow in Vissum Corporación Alicante Universidad Miguel HernándezAlicanteSpain Avda de Denia s/n Edificio Vissum03016 AlicanteSpain

After nearly three decades of innovation in excimer laser,today we are presented with a state of the art generation targeting minimally invasive refractive surgery with high speed laser,faster trackers,pupil monitoring systems and better customization *** systems are capable of delivering better treatments with less induced postoperative high order *** results reported by many authors had confirmed the superiority in efficiency and safety profiles of this generation compared to previous ***,current technology is facing major challenges in the correction of high hyperopic errors and in presbyopic treatments,with upgrades in ablation centration and thermal control needed,which will ensure better biomechanical results,as a step closer to perfection in refractive surgery.

关键词： Refractive surgery Excimer laser 6^(th)Generation

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electronic and magnetic properties of V-and Cr-doped zinc-blende AlN

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Communications in Theoretical Physics 2021年第12期73卷 168-175页

作者： T el-Achari F Goumrhar l B Drissi M Drissi el Bouzaidi R Ahl laamara lPHE-Modeling and Simulations Faculty Of SciencesMohammed V University in RabatMorocco Centre of Physics and Mathematics CPM-MoroccoMohammed V University in RabatMorocco Higher School of Education and Training of el Jadida(ESEF) Chouaib Doukkali UniversityEl JadidaMorocco laboratoire des Sciences de l’lngenieur pour l’Energie Ecole Nationale des Sciences Appliquees d El Jadida(ENSA-J)BP 1166EL Jadida Plateau24002Morocco College of Physical and Chemical Sciences Hassan II Academy of Sciences and TechnologyKm 4Avenue Mohammed VIRabatMorocco national School of Architecture of Tetouan(Ena) Abdelmalek Essaadi UniversityTetouanMorocco

The electronic and magnetic properties of the zinc-blende aluminum nitride doped with V and Cr are studied using the density functional theory(DFT),namely the KKR-CPA-PBE *** Al N is found to be a wide band gap semiconductor,and doping V and Cr single impurities generate ferromagnetic half-metallic ***,the values of the formation energy reveal that these compounds are stable systems for all dopant concentrations.A self-consistent energy minimization scheme determines the ferromagnetic state as the stable magnetic state for V-and Cr-doping Al N.A double exchange mechanism is identified as the mechanism responsible for magnetism in our *** increasing doping impurities,the total magnetic moments increase linearly and the Curie temperature TC,calculated using the mean-field approximation,shows a significant *** present findings reveal Cr-and V-doped zincblende Al N as potential candidates for high Curie temperature ferromagnetic materials.

关键词： AlN compounds CPA-KKR-GGA method Curie temperature Ferromagnetic half-Metals TM dopants

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