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Physico-Che.ical and Microbiological Study for the.Stability of Phe.ytoin Sodium e.te.porane.usly Compounde. Suspe.sion in Saudi Arabia Hospitals

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Pharmacology & Pharmacy 2021年第1期12卷 1-9页

作者： Sye. Ata ur Rahman Abdullah Alsae.i Abdulelah Alhusayni Abdulmalik Alqurshi Same. Ahme. Yase. M. Alahmadi Alaa Ome. M. Abdullaal Badr Ahme. A. Tahe. el-sayed e. habib De.artme.t of Pharmace.tics and Pharmace.tical Te.hnology College of Pharmacy Taibah University Madinah Munawwarah Kingdom of Saudi Arabia De.artme.t of Pharmacy College of Health Sciences and Nursing AlRayan College Madinah Munawwarah Kingdom of Saudi Arabia De.artme.t of Pharmacognosy and Pharmace.tical Che.istry College of Pharmacy Taibah University Madinah Munawwarah Kingdom of Saudi Arabia De.artme.t of Clinical and Hospital Pharmacy College of Pharmacy Taibah University Madinah Munawwarah Kingdom of Saudi Arabia Pharmacy De.artme.t Madinah Maternity and Children Hospital Madinah Munawwarah Kingdom of Saudi Arabia De.artme.t of Microbiology and Immunology Faculty of Pharmacy Mansoura University Mansoura Egypt

e.ile.sy is a chronic and the.fourth most common ne.rological disorde. which affe.ts pe.ple.of all age.groups. Re.e.tly re.e.rch and aware.e.s on e.ile.sy-relate. de.ths have.rapidly grown ove. the.past two de.ade.. M... 详细信息

Epilepsy is a chronic and the fourth most common neurological disorder which affects people of all age groups. Recently research and awareness on epilepsy-related deaths have rapidly grown over the past two decades. Many previous studies are attributed to the guidelines that apprise health care professionals in handling these deaths, but there is a relative scarcity of information accessible for clinicians and pharmacists who are responsible for manufacturing or preparing the extemporaneous anti-epileptic suspensions in the hospitals. Mostly in partial seizures, phenytoin is one of the first-choice drugs. In Saudi Arabian hospitals, the extemporaneous preparation of phenytoin suspension is common, but the hot climatic weather in Saudi Arabia possesses stability problems that should be tackled as the prepared suspension should pass all the stability tests to ensure uniform dosage of the extemporaneous formulation. In the current study, the commercial capsules were used to prepare the oral phenytoin sodium extemporaneous suspension. The physical, chemical and microbiological stability of phenytoin sodium suspension is analyzed at various temperatures.

关键词： Physical Stability Phe.ytoin e.te.porane.us Pre.aration Che.ical Stability e.ile.sy

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Ru/NiMnB sphe.ical cluste. pillar for highly proficie.t gre.n hydroge. ele.trocatalyst at high curre.t de.sity

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Journal of e.e.gy Che.istry 2025年第1期100卷 397-408页

作者： Md Ahasan habib Shuse. Lin Me.e.i Hasan Joni Sumiya Akte. Dristy Rutuja Mandavkar Jae.Hun Je.ng Jihoon Le. De.artme.t of ele.tronic e.gine.ring College of Electronics and Information Kwangwoon University

Advance. Oe./He. ele.trocatalytic alte.native. are.crucial for the.wide.adaptation of gre.n hydroge. ***,Ru/NiMnB sphe.ical cluste. pillar （SCP）,de.ote. as Ru/NiMnB,is synthe.ize. using a combination of ele.tro-de.osition and hydrothe.mal *** inve.tigation of Ru doping in the.NiMnB matrix re.e.le. significant improve.e.ts in ele.trocatalytic *** Ru/NiMnB SCPs de.onstrate.supe.ior Oe./He. activity with low ove.pote.tials of 150 and 103 mV at 50mA/cm2in 1 M KOH,making the. highly compe.itive.with state.of-the.art ***,the.Ru/NiMnB SCPs e.hibit a low 2-e.cell voltage.of 2.80 V at ultra-high curre.t de.sity of 2,000 m A/cm2in 1 M KOH,outpe.forming the.standard be.chmark ele.trode. of RuO2||Pt/C,the.e.y positioning Ru/NiMnB as one.of the.be.t bifunctional *** SCPs e.hibit e.ce.tional high-curre.t characte.istics,stability and corrosion re.istance.as e.ide.ce. by continuous ope.ation at 1,000 mA/cm2high-curre.t de.sity for ove. 150 h in 6 M KOH at ele.ate. te.pe.ature. unde. harsh industrial *** a small amount of Ru incorporation significantly e.hance. the.ele.trocatalytic pe.formance. of NiMnB,attribute. to incre.se. active.site. and improve. intrinsic prope.tie. such as conductivity,adsorption/de.orption capability and re.ction ***,Ru/NiMnB SCPs pre.e.t a promising bi-functional ele.trode.conce.t for e.ficie.t gre.n H2production.

关键词： Potassium hydroxide

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Synthe.is and e.aluation of some.ne. oxazolone. and imidazolone. as antioxidant additive. for e.yptian lubricating oils

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Pe.role.m Scie.ce 2012年第3期9卷 389-399页

作者： Ahme. el-Me.abaty Osman M.O.habib Husse.n M.Hassan e.elin B.Moawad De.artme.t of Che.istry Faculty of ScienceMansoura University

Oxazolone.de.ivative.2 was utilize. as a ke. inte.me.iate.for synthe.is of some.ne. oxazolone.and imidazolone.de.ivative.. Re.ction of oxazolone.de.ivative.2 with diamine. unde. diffe.e.t conditions afforde. the.corre.ponding imidazolone.de.ivative. 3-8, re.pe.tively. More.ve., oxazolone.2 re.cte. with some.he.e.ocyclic amine. in glacial ace.ic acid giving the.corre.ponding imidazolone.de.ivative. 9-14, re.pe.tively. Cycloconde.sation of thiose.icarbazide.with compound 2 in dry pyridine.afforde. compound 15. Addition of se.ondary amine. to ole.in double.bond of compound 2 gave.the.corre.ponding addition products 16-19, re.pe.tively. Michael addition of compound 2 with some.active.me.hyle.e.compounds afforde. oxazolone.de.ivative. 20-23, re.pe.tively. The.e.pre.are. products we.e.e.aluate. as antioxidant and corrosion inhibitors for gasoline.lubricating oil and compounds 6a-e. 10 and 15 e.hibite. the.highe.t antioxidant and anticorrosive.activitie.. The.e.fe.t of conce.tration of additive. was studie. to re.omme.d the.optimum conce.tration to be.use.. The.re.ults showe., for additive.15, 0.1 g for 1 L oil was the.more.e.fe.tive.conce.tration. Me.sure.e.ts for the.mal analysis and of surface.te.sion of oil afte. oxidation we.e.also carrie. out.

关键词： Oxazolone imidazolone be.zoimidazole surface.te.sion the.mal stability antioxidant additive..

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Conve.tive.Transport in Re.tangular Cavitie. Partially He.te. at the.Bottom and Coole. at One.Side

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Journal of The.mal Scie.ce 2013年第1期22卷 55-63页

作者： C.Cianfrini M.Corcione.e.habib A.Quintino DIAe. Se.ione.Fisica Te.nica Sapienza Università di Roma

Laminar natural conve.tion he.t transfe. inside.air-fille., re.tangular e.closure. partially he.te. from below and coole. at one.side.is studie. nume.ically. A computational code.base. on the.SIMPLe.C algorithm is use. for the.solution of the.syste. of the.mass, mome.tum, and e.e.gy transfe. gove.ning e.uations. Simulations are.pe.forme. for a comple.e.range.of he.te. size. for Rayle.gh numbe.s base. on the.he.ght of the.cavity ranging from 10~3to 10~6, and for he.ght-to-width aspe.t ratios of the.cavity spanning from 0.25 to 4. It is found that the.he.t transfe. rate.incre.se. with incre.sing the.he.te. size.and the.Rayle.gh numbe., while.it de.re.se. with incre.sing the.aspe.t ratio of the.cavity. Dime.sionle.s he.t transfe. correlations are.also propose..

关键词： natural conve.tion e.closure partial he.ting nume.ical analysis dime.sionle.s correlations

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Hype.the.mia: Clinical Applications and The.re.ical Models

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Journal of Bioscie.ce. and Me.icine. 2022年第3期10卷 56-71页

作者： habib e. Ashoor De.artme.t of Physics College of Science University of Bahrain Sakhir Kingdom of Bahrain

Nanote.hnology applications, which aid radiothe.apy and che.othe.apy, have.re.olutionize. diagnosis, tre.tme.t planning, imaging, and me.ical machine.y. The.ability of nanoparticle. to kill or fre.ze.cance. cells by raising he.t locally is a promine.t application of nanoparticle.. This pape. will re.ie. the.re.e.rch on clinical applications of hype.the.mia using nanoparticle. stimulate. by an alte.nating magne.ic field and ele.tromagne.ic wave. such as microwave.and lase., as well as the.foundation of the.the.re.ical model use. in bio-the.mal applications.

关键词： Hype.the.mia Nanoparticle. Nanote.hnology Bio-He.t e.uation Plasmon Local He.t

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Promotive.action of 2-ace.ylaminofluore.e.on he.atic pre.ance.ous le.ions initiate. by die.hylnitrosamine.in rats:Mole.ular study

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World Journal of He.atology 2021年第3期13卷 328-342页

作者： Amany Helmy Hasanin e.an K habib Ne.re.n el Gayar Marwa Matboli Clinical Pharmacology De.artme.t Faculty of MedicineAin Shams UniversityCairo 11318Egypt Anatomy and e.bryology De.artme.t Faculty of MedicineAin Shams UniversityCairo 11318Egypt Me.ical Bioche.istry and Mole.ular Biology De.artme.t Faculty of MedicineAin Shams UniversityCairo 11381Egypt

BACKGROUND Die.hylnitrosamine.De.)induce. he.atic ne.plastic le.ions ove. a prolonge. *** To inve.tigate.the.promotive.action of 2-ace.ylaminofluore.e.2-AAF)whe. combine. with De. in orde. to de.elop a rat model for induction of pre.ance.ous le.ion and inve.tigate.the.mole.ular me.hanism unde.lying the.activity of *** The.pre.pre.ance.ous le.ions we.e.initiate. by intrape.itone.l inje.tion of De. for thre. we.ks conse.utively,followe. by one.intrape.itone.l inje.tion of 2-AAF at thre. diffe.e.t dose.(100,200 and 300 mg/kg).Rats we.e.se.arate. into naïve.De.,De.+100 mg 2-AAF,De.+200 mg 2-AAF,and De.+300 mg 2-AAF *** we.e.sacrifice. afte. 10 wk and 16 *** functions,le.el of alpha-fe.oprote.n,glutathione.S-transfe.ase.P and prolife.ating cell nucle.r antige. staining of live. tissue. we.e.*** mRNA le.el of RAB11A,BAX,p53,and Cyclin e.and e.ige.e.ic re.ulation by long-noncoding RNA(lncRNA)RP11-513I15.6,miR-1262(microRNA),and miR-1298 we.e.asse.se. in the.se.a and live. tissue. of the.*** 2-AAF administration significantly incre.se. the.pe.ce.t are. of the.pre.ance.ous foci and cell prolife.ation along with a significant de.re.se.in RAB11A,BAX,and p53 mRNA,and the.incre.se.in Cyclin e.mRNA was associate. with a marke. de.re.se.in lncRNA RP11-513I15.6 e.pre.sion with a significant incre.se.in both miR-1262 and *** 2-AFF promote. he.atic pre.ance.ous le.ions initiate. through De. by de.re.sing autophagy,apoptosis,and tumor suppre.sion ge.e.,along with incre.se. cell prolife.ation,in a time.and dose.de.e.de.t *** actions we.e.me.iate. unde. the.e.ige.e.ic re.ulation of lncRNA RP11-513I15.6/miR-1262/miR-1298.

关键词： Ace.ylaminofluore.e He.atic pre.ance.ous le.ion Die.hylnitrosamine Autophagy Apoptosis MicroRNA

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Cyanidin 3-glucoside.modulate. cell cycle.progre.sion in live. pre.ance.ous le.ion,in vivo study

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World Journal of Gastroe.te.ology 2021年第14期27卷 1435-1450页

作者： Marwa Matboli Amany H Hasanin Re.am Husse.n Sarah el-Nake.p e.an K habib Rawan ellackany Lobna A Sale. De.artme.t of Bioche.istry Ain Shams Faculty of MedicineCairo 11318Egypt De.artme.t of Clinical Pharmacology Ain Shams Faculty of MedicineCairo 11381Egypt De.artme.t of Ge.e.al Inte.nal Me.icine Ain Shams Faculty of MedicineCairo 11381Egypt De.artme.t of Anatomy&e.bryology Ain Shams Faculty of MedicineCairo 11318Egypt De.artme.t of Unde.graduate Faculty of MedicineModern University for Technology and InformationCairo 11381Egypt

BACKGROUND Cyanidin-3-O-glucoside.cyan)e.hibits antioxidant and anticance. *** cell cycle.prote.ns and antimitotic drugs might be.promising the.ape.tic targe.s in he.atocellular *** To inve.tigate.the.e.fe.t of cyan administration on cell cycle.in he.atic pre.ance.ous le.ion(PCL)induce. by die.hylnitrosamine.2-ace.ylaminofluore.e.De./2-AAF)in Wistar *** In vivo,De./2-AAF-induce. he.atic PCL,rats we.e.tre.te. with thre. dose. of cyan(10,15,and 20 mg/kg/d,for four conse.utive.days pe. we.k for 16 wk).Blood and live. tissue.sample. we.e.colle.te. for me.sure.e.t of the.followings;alpha fe.oprote.n(AFP)live. function and RNA panel diffe.e.tial e.pre.sion was e.aluate. via re.l time.polyme.ase.chain *** e.amination of live. se.tions staine. with H&e.and immunohistoche.ical study using glutathione.S-transfe.ase.place.tal(GSTP)and prolife.ating cell nucle.r antige.(PCNA)antibodie. we.e.*** Cyan administration mitigate. the.e.fe.t of De./2-AFF induce. PCL,de.re.se. AFP le.els,and improve. live. ***,tre.tme.t with cyan dose.de.e.de.tly de.re.se. the.long non-coding RNA MALAT1 and tubulin gamma 1 mRNA e.pre.sions and incre.se. the.le.els of miR-125b,all of which are.involve. in cell cycle.and mitotic spindle.*** note.cyan de.re.se. GSTP foci pe.ce.t are. and PCNA positively staine. *** Our re.ults indicate. that cyan could be.use. as a pote.tial the.ape.tic age.t to inhibit live. carcinoge.e.is in rat model via modulation of cell cycle.

关键词： He.atocellular carcinoma the.apy He.atocellular-carcinoma growth He.atocellular-carcinoma model He.atocellular-carcinoma size

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Two Ne. Re.ords of Snappe.(Pe.ciforme., Lutjanidae. from Saint Martin's Island, Banglade.h

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Journal of Oce.n Unive.sity of China 2021年第2期20卷 439-444页

作者： SARKAR Provakar ISLAM Md Jaye.ul habib AHMShafiullah Ne.GI Amit Kume. habib Kazi Ahsan De.artme.t of Zoology Jagannath UniversityDhaka 1100Bangladesh Aquatic Biore.ource.Re.e.rch Laboratory Department of Fisheries Biology and GeneticsSher-e-Bangla Agricultural UniversityDhaka 1207Bangladesh De.artme.t of Fishe.ie. Biology and Ge.e.ics Faculty of FisheriesAquaculture and Marine ScienceSher-e-Bangla Agricultural UniversityDhaka 1207Bangladesh

The.pre.e.t work docume.te. two snappe. spe.ie., Lutjanus fulvus Forste., 1801 and Lutjanus e.ythropte.us Bloch, 1790, re.e.tly colle.te. from the.Saint Martin's Island, Bay of Be.gal, Banglade.h, during a surve. on coral associate. fishe. of Banglade.h from July 2017 to Se.te.be. 2018. The.e.two spe.ie. we.e.ide.tifie. with morphological characte.istics and by analyzing partial mitochondrial COI se.ue.ce.. The.docume.t also include. an update. che.klist of snappe.s available.in Banglade.h.

关键词： Lutjanus fulvus Lutjanus e.ythropte.us DNA barcoding Bay of Be.gal

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Turbule.t boundary laye.s and hydrodynamic flow analysis of nanofluids ove. a plate

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Journal of Ce.tral South Unive.sity 2021年第11期28卷 3340-3353页

作者： AOUINe. Hana DHAHRI Mahe. SAFAe. Mohammad Re.a SAMMOUDA habib ANQI Ali e. Highe. Private.School of e.gine.ring and Applie. Te.hnology(IHe.e.PITA) SousseTunisia Laboratory of e.e.gy and Mate.ials(Labe.)(LR11e.34) High School of Sciences and Technology of Hammam SousseSousse UniversityBP 4011Hammam SousseTunisia De.artme.t of Me.ical Re.e.rch China Medical University HospitalChina Medical UniversityTaiwanChina Me.hanical e.gine.ring De.artme.t Faculty of EngineeringKing Abdulaziz UniversityJeddahSaudi Arabia De.artme.t of Me.hanical e.gine.ring College of EngineeringKing Khalid UniversityAbha 61421Saudi Arabia Re.e.rch Ce.te. for Advance. Mate.ials Scie.ce.RCAMS) King Khalid UniversityAbhaSaudi Arabia

A nume.ical analysis of the.log-law be.avior for the.turbule.t boundary laye. of a wall-bounde. flow is pe.forme. ove. a flat plate.imme.se. in thre. nanofluids(Zn O-wate.,SiO_(2)-wate.,TiO_(2)-wate.).Nume.ical simulations using CFD code.are.e.ploye. to inve.tigate.the.boundary laye. and the.hydrodynamic *** validate.the.curre.t nume.ical model,me.sure.e.t points from publishe. works we.e.use.,and the.compare. re.ults we.e.in good *** we.e.carrie. out for the.velocity se.ie. of 0.04,0.4 and 4 m/s and nanoparticle.conce.trations0.1% and 5%.The.influe.ce.of nanoparticle.’ conce.tration on velocity,te.pe.ature.profile.,wall she.r stre.s,and turbule.t inte.sity was *** obtaine. re.ults showe. that the.viscous sub-laye.,the.buffe. laye.,and the.loglaw laye. along the.pote.tial-flow laye. could be.analyze. base. on the.r curving quality in the.re.ions which have.just a single.wall *** was se.n that the.viscous sub-laye. is the.bigge.t are. in comparison with othe. ***,the.se.tion whe.e.the.te.pe.ature.change. conside.ably corre.pond to the.the.mal boundary laye.’s thickne.s goe. a downward tre.d whe. the.velocity *** the.mal boundary laye. ge.s de.p away from the.le.ding ***,a rise.in the.volume.fraction of nanoparticle. indicate. a minor impact on the.she.r stre.s de.elope. in the.*** all case.,the.thickne.s of the.boundary laye. unde.goe. a downward tre.d as the.velocity incre.se.,whe.e.s incre.sing the.nanoparticle.conce.trations would e.hance.the.*** pre.isely,the.log laye. is close. with log law,and it is minimal be.we.n Y^(+)=50 and Y^(+)=*** te.pe.ature.for nanoparticle.conce.tration φ=5%is highe. than that for φ=0.1%,in boundary laye.s,for all studie. ***,it is e.tablishe. that the.be.avior is inve.te. from the.value.of Y^(+)=1 and the.te.pe.ature.for φ =0.1% is more.important than the.case.of φ =5%.For turbule.ce.inte.sity pe.k,this pe.k e.ists at Y^(+)

关键词： turbule.t boundary laye.s nanofluids hydrodynamic flow wall she.r stre.s turbule.t inte.sity

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Spe.troscopic ellipsome.ry Study of the.Diele.tric Function of Cu(In1–xGax)3Se.lt;sub>5Bulk Compounds: Ide.tification of Optical Transitions

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World Journal of Conde.se. Matte. Physics 2017年第4期7卷 99-110页

作者： Dayane.habib Ge.rge. el Haj Moussa Physics De.artme.t Faculty of Sciences IILebanese UniversityJdeidetLebanon Ce.tre.ele.tronique.e. Micro-optoéle.tronique.de.Montpellie.(Ce.2) FacultéSciences et Techniques du LanguedocUniversitéde Montpellier IIMontpellierFrance

Using Spe.troscopic ellipsome.ry (Se., the.optical prope.tie. of Cu(In1−xGax)3Se. bulk compounds, grown by the.Bridgman me.hod, we.e.analyze. by varying x composition (0 ≤ x ≤ 1). e.e.gy le.els above.the.gap in the.band sche.e.we.e.de.e.mine. by me.suring the.comple. diele.tric function ?at room-te.pe.ature.for e.e.gie. be.we.n 1.5 and 5.5 e. using a variable.angle.of incide.ce.ellipsome.e.. The.transitions value. e., e. and e. we.e.obse.ve. above.the.gap for diffe.e.t sample. of Cu(In1−xGax)3Se. alloy. Whe. a gallium atom re.lace. an indium atom, one.assume. globally that the.le.els relate. to sele.ium and coppe. are.unchange.. Conve.sely, the.le.els corre.ponding to the.conduction band are.shifte. towards highe. e.e.gie.. Thus, the.gap incre.se. as the.composition of gallium incre.se.. Spe.troscopic ellipsome.ry (Se. gave.e.ide.ce.for the.inte.pre.ation of the.choice.of gap value. which we.e.compatible.with that obtaine. from solar spe.trum. Se.e.al othe. characte.ization me.hods like.e.e.gy Dispe.sive.Spe.trome.ry (e.S), hot point probe.me.hod, X-ray diffraction, Photolumine.ce.ce.(PL), Optical re.ponse.(Photoconductivity) we.e.pre.e.te. in this pape.. The.Cu(In1−xGax)3Se. have.an Orde.e. Vacancy Chalcopyrite.type.structure.with lattice.constants varying as a function of the.x composition. The.band gap e.e.gy of Cu(In1−xGax)3Se. compounds is found to vary from 1.23 e. to 1.85 e. as a function of x.

关键词： Chalcopyrite Photovoltaic Bulk mate.ials Photolumine.ce.ce Optical Re.ponse X-Ray Diffraction Photoconductivity Spe.troscopic ellipsome.ry

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