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Risk factors of admission for acute colonic diverticulitis in a population-based cohort study: The North Trondelag Health Study, Norway

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World Journal of Gastroenterology 2016年第48期22卷 10663-10672页

作者： Aras Jamal Talabani Stian Lydersen eivind ness-jensen Birger Henning Endreseth Tom-Harald Edna Department of Surgery Levanger Hospital North Trondelag Hospital Trust Regional Centre for Child and Youth Mental Health and Child Welfare - Central Norway Faculty of Medicine Norwegian University of Science and Technology HUNT Research Centre Department of Public Health and General Practice Faculty of Medicine Norwegian University of Science and Technology Upper Gastrointestinal Surgery Department of Molecular Medicine and Surgery Karolinska Institutet Karolinska University Hospital Clinic of Medicine St. Olav’s Hospital Trondheim University Hospital Clinic of Surgery St. Olav’s Hospital Trondheim University Hospital Institute of Cancer Research and Molecular Medicine Norwegian University of Science and Technology Unit for Applied Clinical Research Institute of Cancer Research and Molecular Medicine Norwegian University of Science and Technology

AIM To assess risk factors of hospital admission for acute colonic *** The study was conducted as part of the second wave of the population-based North Trondelag Health Study(HUNT2), performed in North Trondelag County, Norway, 1995 to 1997. The study consisted of 42570 participants(65.1% from HUNT2) who were followed up from 1998 to 2012. Of these, 22436(52.7%) were females. The cases were defined as those 358 participants admitted with acute colonic diverticulitis during follow-up. The remaining participants were used as controls. Univariable and multivariable Cox regression analyses was used for each sex separately after multiple imputation to calculate *** Multivariable Cox regression analyses showed that increasing age increased the risk of admission for acute colonic diverticulitis: Comparing with ages 70 years, HR = 6.19, P ness(HR = 2.57, P < 0.001) and living in rural areas(HR = 1.74, P = 0.007) increased the risk. Level of education, physical activity, constipation and type of bread eaten showed no association with admission for acute colonic *** The risk of hospital admission for acute colonic diverticulitis increased with increasing age, in obese individuals, in ever cigarette smoking females and in males living in rural areas.

关键词： Acute colonic diverticulitis North Trondelag Health Study Risk factors Multivariable Cox regression analysis Multiple imputation

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