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Exploring the novel role of oligodendrocyte precursor cells in phagocytosis:beyond myelinogenesis

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Neural Regeneration Research 2025年第2期20卷 473-474页

作者： Gen Hamanaka Ken arai Neuroprotection Research Laboratories Departments of Radiology and NeurologyMassachusetts General Hospital and Harvard Medical SchoolCharlestownMAUSA

Roles of oligodendrocyte precursor cells in the central nervous system:Oligodendrocyte precursor cells(OPCs)have long been recognized for their critical role as precursors to oligodendrocytes,the primary myelin-producing *** precursors,OPCs mature and differentiate into oligodendrocytes,which contribute significantly to the formation of myelin sheaths around *** myelination,which is critical for the conduction of salutatory nerve impulses in the cerebral white matter,underscores the classical role of oligodendrocytes in central nervous system(CNS)***,because oligodendrocytes are differentiated cells that cannot proliferate.

关键词： critical system conduction

Inelastic constitutive equation of plasma-sprayed ceramic thermal barrier coatings

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Acta Metallurgica Sinica(English Letters) 2011年第2期24卷 161-168页

作者： Masayuki arai Materials Science Research Laboratory Central Research Institute of Electric Power Industry

Ceramic thermal barrier coatings （TBCs） are a very important technology for protecting the hot parts of gas turbines （GTs） from a high-temperature environment. The coating stress generated in the operation of GTs brings cracking and peeling damage to the TBCs. Thus, it is necessary to evaluate precisely such coating stress in a TBC system. We have obtained a stress-strain curve for a freestanding ceramic coat specimen peeled from a TBC coated substrate by conducting the bending test. The test results have revealed that the ceramic coating deforms nonlinearly with the applied loading. In this study, an inelastic constitutive equation for the ceramic thermal barrier coatings deposited by APS is developed. The obtained results are as follows：（1） the micromechanics-based constitutive equation was formulated with micro crack density formed at splat boundary, and （2） it was shown that the numerical results for a nonlinearly deformed beam simulated by the developed constitutive equation agreed with the experimental results obtained by cantilever bending tests.

关键词： Inelastic constitutive equation Thermal barrier coating Gas turbine Micromechanics

How to Transmit Disaster Information Effectively:A Linguistic Perspective on Japan’s Tsunami Warnings and Evacuation Instructions

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International Journal of Disaster Risk Science 2013年第3期4卷 150-158页

作者： Kyoko arai Faculty of Business Administration Toyo UniversityTokyo 112-8606Japan

When the disastrous tsunamis hit East Japan on 11 March 2011, the hi-tech information transmission system that is the pride of Japan was unable to send out the Tsunami Warnings effectively;many lives were lost as a result. Subsequently, the Japan Meteorological Agency(JMA) set up a committee of experts to improve the overall system. Last year as a result of their meetings, a report on The Improvement of the Information Text for the Tsunami Warnings was announced. The changes are, however, problematic from the linguistics perspective as the committee did not include any experts in the field. This study examines a range of recordings of the Tsunami Warnings and the Evacuation Instructionsi given for the East Japan tsunami disaster from the perspective of linguistics, especially pragmatics, whose main objective is to discover how recipients interpret verbal messages. The aim of this article is to propose further improvement to the transmission system of Tsunami Warnings and Evacuation Instructions. This study also emphasizes the necessity and importance of reexamining the overall disaster information transmission issue in Japan, from the linguistics perspective.

关键词： disaster Japan recording

Detection of small delamination in mullite/Si/SiC model EBC system by pulse thermography

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Journal of Advanced Ceramics 2019年第3期8卷 438-447页

作者： Yutaro arai Ryo INOUE Department of Materials Science and Technology Tokyo University of Science6-3-1NiijyukuKatsushika-kuTokyo125-8585Japan Department of Mechanical Engineering Tokyo University of Science6-3-1NiijyukuKatsushika-kuTokyo125-8585Japan

The pulse thermography(PT) technique was applied to the detection of the delamination of a multi-layered coating system composed of mullite/Si onto a reaction-bonded Si C substrate. The potential evaluation was carried out in order to detect internal delamination in multi-layered material system. Moreover, the observation of the cross sections and 3D views obtained by X-ray computed tomography(CT) indicated that the delamination occurred at the interface between the top coat and the bond coat layers. The changes in the temperature distribution obtained by PT indicated the existence of a delamination area in the top coat layer of the mullite. In particular, the lower temperature region corresponded to the delamination area. The experimental results confirmed that the PT technique is effective with respect to the internal delamination of multi-layered coating system.

关键词： environmental barrier coatings (EBCs) delamination pulse thermography (PT) multi-layer image processing

Formation of anorthosite on the Moon through magma ocean fractional crystallization

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Geoscience Frontiers 2017年第2期8卷 299-308页

作者： Tatsuyuki arai Shigenori Maruyama Department of Earth and Planetary Sciences Tokyo Institute of Technology2-12-10okayamaMeguro-kuTokyo 152-8551Japan Earth-Life Science Institute Tokyo Institute of Technology2-12-1 OokayamaMeguro-kuTokyo 152-8551Japan

Lunar anorthosite is a major rock of the lunar highlands,which formed as a result of plagioclasefloatation in the lunar magma ocean（LMO）.Constraints on the sufficient conditions that resulted in the formation of a thick pure anorthosite（mode of plagioclase 〉95 vol.%） is a key to reveal the early magmatic evolution of the terrestrial *** form the pure lunar anorthosite,plagioclase should have separated from the magma ocean with low crystal *** networks of plagioclase and mafic minerals develop when the crystal fraction in the magma（φ） is higher than ca.40-60 vol.%,which inhibit the formation of pure *** contrast,when φ is small,the magma ocean is highly turbulent,and plagioclase is likely to become entrained in the turbulent magma rather than separated from the *** determine the necessary conditions in which anorthosite forms from the LMO,this study adopted the energy criterion formulated by *** composition of melt,temperature,and pressure when plagioclase crystallizes are constrained by using MELTS/pMELTS to calculate the density and viscosity of the *** plagioclase starts to crystallize,the Mg~# of melt becomes 0.59 at 1291 *** density of the melt is smaller than that of plagioclase for P 〉 2.1 kbar（ca.50 km deep）,and the critical diameter of plagioclase to separate from the melt becomes larger than the typical crystal diameter of plagioclase（1.8-3 cm）.This suggests that plagioclase is likely entrained in the LMO just after the plagioclase starts to *** the Mg~# of melt becomes 0.54 at 1263 C,the density of melt becomes larger than that of plagioclase even for 0 *** the Mg~# of melt decreases down to 0.46 at 1218 C,the critical diameter of plagioclase to separate from the melt becomes 1.5-2.5 cm,which is nearly equal to the typical plagioclase of the lunar *** suggests that plagioclase could separate from the *** of the differences between the Earth and the Moon is the presenc

关键词： Moon Anorthosite Magma ocean MELTS Fractional crystallization

MANIPULATION KINEMATICS ON DEXTEROUS HANDS CONSIDERING PURE ROLLING CONTACTS AS PASSIVE JOINTS

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Chinese Journal of Mechanical Engineering 2005年第3期18卷 361-365页

作者： Yang Yang Tamio arai School of Mechanical Engineering and Automation Beihang University Beijing 100083 China Department of Precision Machinery Engineering Graduate School of Engineering The University of Tokyo Tokyo 113-8656 Japan

The manipulation and constraint equations are established by considering the pure rolling motion in a dexterous hand as two passive joints. According to mapping relation among the motion of the system, the differential kinematics and mobility are studied. The minimal structure for realizing the task motion of the object is obtained, and the conditions for dexterous manipulation are presented. Finally, some rolling manipulations are used as examples to demonstrate the applicability of approach proposed.

关键词： Pure rolling Passive joints Differential kinematics Dexterous hands

The impact of AI: can a robot get into the University of Tokyo?

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National Science Review 2015年第2期2卷 135-136页

作者： Noriko H.arai National Institute of Informatics

The ‘Todai Robot Project(Can a robot get into the University of Tokyo?)’ was initiated by the National Institute of Informatics(NII),the Japan’s only general academic research institution of informatics,in 2011 as ... 详细信息

关键词： can a robot get into the University of Tokyo The impact of AI

Numerical model of local scour considering the unsteady sediment inflow and sediment sorting: Application to scour upstream of slit weir

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International Journal of Sediment Research 2022年第4期37卷 469-483页

作者： Kazuyuki Ota Takahiro Sato Ryosuke arai Meteorology and Fluid Science Division Central Research Institute of Electric Power Industry

The current study proposes a novel framework for the numerical model for estimating the temporal scour considering unsteady sediment inflow and the sediment sorting process. The framework was applied to local scour upstream of a slit weir. The scour model is based on an ordinary nonlinear differential equation derived from sediment continuity and scour rate equations. A one-dimensional(1-D)Boussinesq-type model coupled with nonequilibrium sediment transport was incorporated in the scour model to consider unsteady sediment inflow. In addition, a mixing layer approach was incorporated to determine temporal variations in particle size in the scour hole. The proposed framework was validated using scour experiments conducted under conditions that include non-uniform sediment, live-bed scour,and unsteady flow rate. The simulation results showed satisfactory agreement with experimental results for the scour upstream of a slit weir. The proposed model appropriately explained the hysteresis process for flow unsteadiness, refilling process for live-bed scour, and armoring process for non-uniform sediments. In addition, the model framework proposed in the current study is applicable to local scour around other hydraulic structures(e.g., bridge piers) upon establishing the scour rate equation. Therefore, the current study provides a novel approach for modeling temporal scour that is required to consider unsteady sediment inflow and sediment sorting.

关键词： Local scour Temporal scour Mixing layer theory Slit weir Non-equilibrium bed load

Numerical and experimental analyses for bearing capacity of rigid strip footing subjected to eccentric load

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Journal of Central South University 2014年第10期21卷 3983-3992页

作者：卢谅王宗建 K.arai School of Civil Engineering Chongqing University Key Laboratory of New Technology for Construction of Cities in Mountain Area of Ministry of Education (Chongqing University) Institute of Geotechnical Engineering Chongqing Jiaotong University NPO Research Institute of Ground Disaster Prevention of Fukui Region

A footing may get an eccentric load caused by earthquake or wind, thus the bearing capacity of footing subjected to eccentric load become a fundamental geotechnical problem. The conventional limit equilibrium method used for this problem usually evaluates the material properties only by its final strength. But the classical finite element method(FEM) does not necessarily provide a clear collapse mechanism associated with the yield condition of elements. To overcome these defects, a numerical procedure is proposed to create an explicit collapse mode combining a modified smeared shear band approach with a modified initial stress method. To understand the practical performance of sand foundation and verify the performance of the proposed procedure applied to the practical problems, the computing results were compared with the laboratory model tests results and some conventional solutions. Furthermore, because the proposed numerical procedure employs a simple elasto-plastic model which requires a small number of soil parameters, it may be applied directly to practical design works.

关键词： bearing capacity eccentric load slip surface shear band finite element method model test