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钢结构(中英文) 2009年第10期 86-86页

作者： Tomohiro Yokozeki eiichi hara

提出碳/环氧复合材料作为柔性梁材料的可行性。对相同树脂基体的单向碳纤维复合材料和玻璃纤维/环氧复合材料的扭转疲劳性能进行研究。碳纤维复合材料的初始扭转刚度几乎与玻璃纤维复合材料相同。采用有限元计算的扭转刚度与试验结果吻... 详细信息

提出碳/环氧复合材料作为柔性梁材料的可行性。对相同树脂基体的单向碳纤维复合材料和玻璃纤维/环氧复合材料的扭转疲劳性能进行研究。碳纤维复合材料的初始扭转刚度几乎与玻璃纤维复合材料相同。采用有限元计算的扭转刚度与试验结果吻合:扭转刚度主要受控于材料的剪切刚度。通过控制正弦波扭转的角度,进行了恒定受拉轴向荷载下的扭转疲劳试验。尽管根据循环次数降低了扭矩和扭转刚度振幅,无论是碳纤维还是玻璃纤维复合材料都没出现严重的破坏现象。X-射线CT的检查结果以及有限元计算的结果显示:主要是沿着纤维方向裂缝扩展引起扭转刚度的退化,碳纤维扭转疲劳寿命高于玻璃纤维复合材料。因此,根据扭转刚度和张拉-扭转疲劳性能,证实碳纤维具有很好的性能,可作为柔性梁的抗扭材料。

关键词：碳纤维玻璃纤维疲劳基体开裂

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Clinical relevance of fluorodeoxyglucose positron emission tomography/computed tomography and magnifying endoscopy with narrow band imaging in decision-making regarding the treatment strategy for esophageal squamous cell carcinoma

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World Journal of Gastroenterology 2019年第46期25卷 6767-6780页

作者： Kazuhiro Toriyama Masahiro Tajika Tsutomu Tanaka Makoto Ishihara Yutaka Hirayama Sachiyo Onishi Nobumasa Mizuno Takamichi Kuwahara Nozomi Okuno Shinpei Matsumoto eiichi Sasaki Tetsuya Abe Yasushi Yatabe Kazuo hara Keitaro Matsuo Tsuneo Tamaki Yasumasa Niwa Department of Gastroenterology Aichi Cancer Center HospitalNagoya 464-8681Japan Department of Endoscopy Aichi Cancer Center HospitalNagoya 464-8681Japan Department of Gastroenterology Anjo Kosei HospitalAnjo 446-8602Japan Department of Pathology and Molecular Diagnostics Aichi Cancer Center HospitalNagoya 464-8681Japan Department of Gastroenterological Surgery Aichi Cancer Center HospitalNagoya 464-8681Japan Division of Cancer Epidemiology and Prevention Aichi Cancer Center Research InstituteNagoya 464-8681Japan East Nagoya Imaging Diagnosis Center Nagoya 464-0044Japan

BACKGROUND Recent advances in endoscopic technology,especially magnifying endoscopy with narrow band imaging(ME-NBI)enable us to detect superficial esophageal squamous cell carcinoma(ESCC),but determining the appropriate method of resection,endoscopic resection(ER)vs surgical resection,is often ***,several studies have reported that 18F-fluorodeoxyglucose positron emission tomography(FDG-PET)is a useful indicator for decision-making regarding treatment for superficial ***,there are not enough reports on association between FDG-PET uptake and clinicopathological characteristics of superficial ***,there are not enough reports on evaluating the usefulness of combination of FDG-PET and ME-NBI for determining the treatment strategy for superficial *** study evaluated clinical relevance of FDG-PET and ME-NBI in decision-making regarding the treatment strategy for *** To investigate the association between FDG uptake and the clinicopathological characteristics of superficial ESCC and its usefulness of combination of FDG-PET and ME-NBI for determining the treatment strategy for superficial *** A database of all patients with superficial ESCC who had undergone both MENBI and FDG-PET for pre-treatment staging at Aichi Cancer Center Hospital between January 2008 and November 2018 was retrospectively *** uptake was defined positive or negative whether the primary lesion was visualized or could be distinguished from the background,or *** invasion depth of ESCC was classified according to the Japan Esophageal *** endpoint is to evaluate the association between FDG uptake and clinicopathological characteristics of superficial *** endpoint is to investigate the efficacy of combination of FDG-PET and ME-NBI for determining the treatment strategy for superficial *** A total of 82 lesions in 82 patients were ***-PET showed positive uptake in 29(35.4%)*** analysis sh

关键词： ^18F-fluorodeoxyglucose positron emission tomography Magnifying endoscopy Narrow band imaging Superficial esophageal cancer Squamous cell carcinoma Treatment strategy

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采用联合全腹腔干切除的胰体尾切除术治疗局部晚期胰体癌:远期结果

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医学信息（手术学分册） 2008年第5期21卷 400-400页

作者： Hirano Satoshi Kondo Satoshi hara Takashi Ambo Yoshiyasu Tanaka eiichi Shichinohe Toshiaki Suzuki On Hazama Kazuaki

目的:联合全腹腔干切除的胰体尾切除术(distal pancreatectomy with en bloe celiac axis resection,DP-CAR)是治疗局部晚期胰体癌的一种新型扩大术,本文旨在分析其远期结果。背景:胰体癌往往波及肝总动脉和/或腹腔干,因此被视为是一种... 详细信息

目的:联合全腹腔干切除的胰体尾切除术(distal pancreatectomy with en bloe celiac axis resection,DP-CAR)是治疗局部晚期胰体癌的一种新型扩大术,本文旨在分析其远期结果。背景:胰体癌往往波及肝总动脉和/或腹腔干,因此被视为是一种无法切除的疾病。我们曾在10例患者及3个早期病例十中报告了DP-CAR的可行性和安全性,但其远期结果仍不得而知。方法:1998年5月至2005年9月期间共有23例患者实施了DP-CAR。由于早期自肠系膜上动脉经由胰十二指肠动脉弓形成了动脉侧支循环通路,[第一段]

关键词：胰体尾切除术远期结果局部晚期胰体癌腹腔干治疗侧支循环通路肝总动脉

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Importance of virological response in the early stage of telaprevir-based triple therapy for hepatitis C

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World Journal of Hepatology 2015年第26期7卷 2688-2695页

作者： Satoshi Hiramine Norihiro Furusyo eiichi Ogawa Makoto Nakamuta Eiji Kajiwara Hideyuki Nomura Kazufumi Dohmen Kazuhiro Takahashi Takeaki Satoh Koichi Azuma Akira Kawano Toshimasa Koyanagi Kazuhiro Kotoh Shinji Shimoda Jun Hayashi Depart- ment of General Internal Medicine Kyushu University Hospital Department of Gastroenterology Kyushu Medical CenterNational Hospital Organization Department of Hepatology Steel Memorial Yahata Hospital the Center for Liver Disease Shin-Kokura Hospital Department of Internal Medicine Chihaya Hospital Department of Medicine Hamanomachi Hospital Center for Liver Disease National Hospital Organization Kokura Medical Center Department of Medicine Kyushu Central Hospital Department of Medicine Kitakyushu Municipal Medical Center Department of Medicine Fukuoka City Hospital Department of Medicine and Bioregulatory Science Graduate School of Medical Sciences Kyushu University Kyushu General Internal Medicine Center Hara- Doi Hospital

AIM: To investigate the efficacy of virological response(VR) to telaprevir(TVR)-based triple therapy in predicting treatment outcome of hepatitis ***: This prospective, multicenter study consisted of 253 Japanese patients infected with hepatitis C virus(HCV) genotype 1b. All received 12 wk of TVR in combination with 24 wk of pegylatedinterferon-α(IFN-α) and ribavirin. Serum HCV RNA was tested at weeks 1, 2, 3, 4, 6, 8, 12, 16, 20, and 24. VR was defined as undetectable serum HCV RNA. Sustained virological response(SVR) was VR at 24 wk after the end of treatment and was regarded as a successful ***: Of 253 patients, 207(81.8%) achieved SVR. The positive predictive value of VR for SVR was 100% at week 2, after which it gradually decreased, and was over 85% to week 12. The negative predictive value(NPV) gradually increased, reaching 100% at week 12. The upslope of the NPV showed a large increase from week 4(40.6%) to week 6(82.4%). There was a moderate concordance between the SVR and VR at week 6(kappa coefficient = 0.44), although other VRs had poor concordance to SVR. Multiple logistic regression analysis extracted VR at week 6(P < 0.0001, OR = 63.8) as an independent factor contributing to SVR. In addition, the interleukin-28 B single nucleotide polymorphism and response to previous pegylated-IFN-α and ribavirin therapy were identified as independent factors for ***: VR at week 6, but not at week 4, is an efficient predictor of both SVR and non-SVR to TVRbased triple therapy.

关键词： Chronic hepatitis C Direct-acting antiviral agent

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