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Correlation, Regression and Path Analyses of Seed Yield Components in <i>Crambe abyssinica</i>, a Promising Industrial Oil Crop

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American Journal of Plant Sciences 2013年第1期4卷 42-47页

作者： Banglian Huang Yiming Yang Tingting Luo Shu Wu Xuezhu Du Detian Cai eibertus n. van loo Bangquan Huang College of Life Science Hubei University Wuhan China Plant Research International Wageningen the Netherlands

In the present study correlation, regression and path analyses were carried out to decide correlations among the agro- nomic traits and their contributions to seed yield per plant in Crambe abyssinica. Partial correlation analysis indicated that plant height (X1) was significantly correlated with branching height and the number of first branches (P 2) was significantly correlated with pod number of primary inflorescence (P 3) was significantly correlated with number of secondary branches (P -grain weight (P 4) was significantly correlated with seed yield per plant (P 7) was significantly correlated with seed yield per plant (P -grain weight (P -grain weight (X8) was significantly correlated with seed yield per plant (P -grain weight contributed significantly to seed yield per plant at P 7) and 1000-grain weight (X8) to seed yield per plant (Y) is Y = 0.006 X7 + 1.222 X8 - 7.191. The path coefficient of pod number per plant to seed yield per plant was 0.967 and that of 1000-grain weight was 0.194. The determination coefficient of pod number per plant and 1000-grain weight to seed yield per plant was 0.983 and the determination coefficient of other agronomic traits was 0.130. Coefficient of variance indicated that the length of primary inflorescence showed the greatest variation, followed by seed yield per plant, pod number per plant, number of secondary branches, branching height, pod number of primary inflorescence, number of first branches, seed yield per plot, 1000-grain weight and plant height. It was suggested that seed yield per plant in Crambe might be improved by increasing the pod number per plant through selection or cultivation, but the negative correlation between pod number per plant and 1000-grain weight also needs to be considered.

关键词： Correlation Crambe abyssinica Path Analysis Regression Seed Yield Components

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Implementation of two high through-put techniques in a novel application:detecting point mutations in large EMS mutated plant populations

Implementation of two high through-put techniques in a novel...

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中国的遗传学研究——遗传学进步推动中国西部经济与社会发展——2011年中国遗传学会大会

作者： Antoine LF Gady Freddy WK Hermans Marion HBJ van de Wal eibertus n van loo Richard GF Visser Christian WB Bachem Wageningen UR Plant BreedingWageningen University and Research CenterPO box 3866700 AJ Wageningen The Netherlands

Background:The establishment of mutant populations together with the strategies for targeted mutation detection has been applied successfully to a large number of organisms including many species in the plant *** efforts have been invested into research on tomato as a model for berry-fruit *** the progress of the tomato sequencing project,reverse genetics becomes an obvious and achievable goal.

关键词： EMS mutated plant mutation detection HRM CSCE

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Predictive factors for percutaneous nephrolithotomy bleeding risks

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Asian Journal of Urology 2024年第1期11卷 105-109页

作者： U Phun loo Chun Hou Yong Guan Chou Teh Urology Department Sarawak General HospitalKuchingMalaysia

Objective:This study aimed to identify predictive factors for percutaneous nephrolithotomy(PCnL)bleeding *** better risk stratification,bleeding in high-risk patient can be anticipated and facilitates early ***:A prospective observational study of PCnL performed at our institution was *** adults with radio-opaque renal stones planned for PCnL were included except those with coagulopathy,planned for additional *** including gender,co-morbidities,body mass index,stone burden,puncture site,tract dilatation size,operative position,surgeon's seniority,and operative duration were studied using stepwise multivariate regression analysis to identify the predictive factors associated with higher estimated hemoglobin(Hb)***:Overall,4.86%patients(n=7)received packed cells *** mean estimated Hb deficiency was 1.3(range 0-6.5)g/dL and the median was 1.0 g/*** multivariate regression analysis revealed that absence of hypertension(p=0.024),puncture site(p=0.027),and operative duration(p=0.023)were significantly associated with higher estimated Hb ***,the effect sizes are rather small with partial eta-squared of 0.037,0.066,and 0.038,*** power obtained was 0.621,0.722,and 0.625,*** factors studied did not correlate with Hb ***:Hypertension,puncture site,and operative duration have significant impact on estimated Hb deficiency during ***,the effect size is rather small despite adequate study power ***,operative position(supine or prone),puncture number,or tract dilatation size did not correlate with Hb *** mainstay of reducing bleeding in PCnL is still meticulous operative *** study findings also suggest that PCnL can be safely done by urology trainees under supervision in suitably selected patient,without increasing risk of bleeding.

关键词： Percutaneous nephrolithotomy Predictive factor Risk factor Bleeding Blood loss

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Using proteomics to compare the molecular structures of sulfide and permeate-depilated sheepskins

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Collagen and Leather 2024年第1期6卷 70-84页

作者： Yi-Hsuan Tu Trevor S.loo Mark L.Patchett Gillian E.norris School of natural Sciences Massey UniversityPalmerston NorthNew Zealand

An environmentally friendly method using real or artificial bovine milk permeate to both depilate and preserve sheepskins has been reported which completely and cleanly removed the wool from the hair follicle and had no detrimental effects on the skin.A proteomic analysis,assessing the relative abundance of proteins in matched permeate-depilated and chemically depilated(sulfide)sheepskins,showed variations in the levels of specific collagen types in the skin's basement membrane and other proteins associated with the *** findings were corroborated by biochemical analyses of matched permeate depilated and raw skin samples,and provide clues to the mechanism of non-invasiveand complete *** also support the observation that permeate-depilated skins were smoother than their sulfide-depilated counterparts and resulted in leather with a superior surface.

关键词： Collagen Collagen crosslinks Glycosaminoglycan Proteomics Relative abundance

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Broad-spectrum ginsentides are principal bioactives in unraveling the cure-all effects of ginseng

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Acta Pharmaceutica Sinica B 2024年第2期14卷 653-666页

作者： Shining loo Antony Kam Bamaprasad Dutta Xiaohong Zhang nan Feng Siu Kwan Sze Chuan-Fa Liu Xiaoliang Wang James P.Tam School of Biological Sciences Nanyang Technological UniversitySingapore 637551Singapore Academy of Pharmacy Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China Department of Biological Sciences Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China Institute of Materia Medica Chinese Academy of Medical SciencesBeijing 100050China Department of Health Sciences Brock UniversityNiagara RegionON L2S 3A1Canada

Stress and illness connection is complex and involves multiple physiological *** ginsengs,reputed for their broad-spectrum“cure-all”effect,are widely prescribed to treat stress and related ***,the identity of ginseng’s“cure-all”medicinal compounds that relieve stress remains ***,we identify ginsentides as the principal bioactives that coordinate multiple systems to restore homeostasis in response to *** are disulfide-rich,cell-penetrating and proteolytic-stable *** affinity-enrichment mass spectrometry target identification together with in vitro,ex vivo and in vivo validations,we show that highly purified or synthetic ginsentides promote vasorelaxation by producing nitric oxide through endothelial cells via intracellular PI3K/Akt signaling pathway,alleviate a1-adrenergic receptor overactivity by reversing phenylephrine-induced constriction of aorta,decrease monocyte adhesion to endothelial cells via CD166/ESAM/CD40 and inhibit P2Y12 receptors to reduce platelet *** administered ginsentides were effective in animal models to reduce ADP-induced platelet aggregation,to prevent collagen and adrenalineinduced pulmonary thrombosis as well as anti-stress behavior of tail suspension and forced swimming tests in ***,these results strongly suggest that ginsentides are the principal panacea compounds of ginsengs because of their ability to target multiple extra-and intra-cellular proteins to reverse stress-induced damages.

关键词： Ginseng Cysteine-rich peptides Microproteins Cure-all Stress Homeostasis

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Challenges and prospects for consumer acceptance of cultured meat

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Journal of Integrative Agriculture 2015年第2期14卷 285-294页

作者： Wim Verbeke Pierre Sans Ellen J van loo Department of Agricultural Economics Ghent UniversityGent B-9000 Belgium InP-EnV Toulouse Toulouse 31076 France UR1303 ALISS INRA Ivry-sur-Seine 94205 France

Consumer acceptance of cultured meat is expected to depend on a wide diversity of determinants ranging from technologyrelated perceptions to product-specific expectations, and including wider contextual factors like media coverage, public involvement, and trust in science, policy and society. This paper discusses the case of cultured meat against this multitude of possible determinants shaping future consumer acceptance or rejection. The paper also presents insights from a primary exploratory study performed in April 2013 with consumers from Flanders（Belgium）（n=180）. The concept of cultured meat was only known（unaided） by 13% of the study participants. After receiving basic information about what cultured meat is, participants expressed favorable expectations about the concept. Only 9% rejected the idea of trying cultured meat, while two thirds hesitated and about quarter indicated to be willing to try it. The provision of additional information about the environmental benefits of cultured meat compared to traditional meat resulted in 43% of the participants indicating to be willing to try this novel food, while another 51% indicated to be ‘maybe＇ willing to do so. Price and sensory expectations emerged as major obstacles. Consumers eating mostly vegetarian meals were less convinced that cultured meat might be healthy, suggesting that vegetarians may not be the ideal primary target group for this novel meat substitute. Although exploratory rather than conclusive, the findings generally underscore doubts among consumers about trying this product when it would become available, and therefore also the challenge for cultured meat to mimic traditional meat in terms of sensory quality at an affordable price in order to become acceptable for future consumers.

关键词： acceptance artificial attitude consumer cultured in vitro meat synthetic

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nitridation of ni-based alloys:thermodynamics,kinetics,and deformation phenomena accompanying internal precipitation

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Rare Metals 2006年第5期25卷 501-511页

作者： Alexander A.Kodentsov Jorma K.Kivilahti Frans J.J.van loo Laboratory of Materials and Interface Chemistry Eindhoven University of TechnologyP.O.Box 5135600 MBEindhovenThe Netherlands Laboratory of Electronics Production Technology Helsinki University of TechnologyFIN-02150 EspooFinland

When a moderately stable phase is precipitated out during an intemal reaction, the behaviour of the penetrating atoms within the diffusion zone can be interpreted based on thermodynamic considerations. Evidence for “up-hill” diffusion of the penetrating species through the matrix towards the precipitation front during the intemal nitridation of ni-Cr alloys at 1125℃ and 6000 bar of n2-pressure was predicted. Such behaviour of nitrogen is opposite to the boundary conditions in Wagner＇s description of internal reactions. A volume change associated with the precipitation reaction resulted in a stress gradient between the alloys surface and the intemal nitridation front. Stress relief occurred mainly by transport of nickel to the gas/metal interface. Pipe diffusion-controlled creep is the dominant stress accommodation mechanism during nitriding of dilute ni-Cr alloys at 700℃ under a flowing nH3 ＋ H2 gas mixture.

关键词： nitridation nickel alloys thermodynamics diffusion internal precipitation

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nGR1改善糖尿病肾病炎症反应的靶点分析及验证

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四川大学学报（自然科学版） 2024年第3期61卷 325-334页

作者：任祥亭吕建珍刘秋霞黄国东王志静李统宇陆世龙 loo Wei‐Yin 广西中医药大学药学院南宁530200 广西中医药大学基础医学院南宁530200 广西国际壮医医院南宁530021 广西中医药大学第一附属医院南宁530023 广西中医药大学瑞康医院南宁530011 广西中医药大学国际教育学院南宁530001

为阐明壮药三七特征皂苷(nGR1)的抗炎特性及其保护肾足细胞的作用,本文运用网络药理学和分子对接技术,探究nGR1改善糖尿病肾病(Dn)炎症分子机制及其潜在靶点.Swiss Target Prediction数据库检索nGR1的靶点;OMIM和Gene Cards数据库检索D... 详细信息

为阐明壮药三七特征皂苷(nGR1)的抗炎特性及其保护肾足细胞的作用,本文运用网络药理学和分子对接技术,探究nGR1改善糖尿病肾病(Dn)炎症分子机制及其潜在靶点.Swiss Target Prediction数据库检索nGR1的靶点;OMIM和Gene Cards数据库检索Dn炎症反应的相关基因;构建交集靶点的蛋白质-蛋白质相互作用(PPI)网络;运用Metascape进行GO和KEGG富集分析.利用Autodock Vina对交集靶点-nGR1进行分子对接,GRAMM-X评估交集靶点-nLRP3炎症小体的亲和力.采用MPC-5细胞进行体外实验验证.结果表明,STAT3、VEGFA为nGR1主要靶点,均与nLRP3密切关联.nGR1干预Dn炎症反应主要涉及PI3K/Akt等信号通路.nGR1降低P-STAT3、VEGFA、nLRP3的表达水平.结果提示,nGR1通过降低STAT3磷酸化水平干预nLRP3的激活、调控VEGFA的表达,改善Dn炎症反应.

关键词：三七皂苷R1 nLRP3炎症小体糖尿病肾病网络药理学分子对接

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Scalable fabrication,compartmentalization and applications of living microtissues

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Bioactive Materials 2023年第1期19卷 392-405页

作者： Maik Schot nuno Araújo-Gomes Bas van loo Tom Kamperman Jeroen Leijten Department of Developmental Bioengineering Faculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteDrienerlolaan 57522NBEnschedethe Netherlands

Living microtissues are used in a multitude of applications as they more closely resemble native tissue physiology,as compared to 2D *** are typically composed of a combination of cells and materials in varying combinations,which are dictated by the applications’design *** applications range wide,from fundamental biological research such as differentiation studies to industrial applications such as cruelty-free meat ***,their translation to industrial and clinical settings has been hindered due to the lack of scalability of microtissue production *** microfluidic processes provide an opportunity to overcome this limitation as they offer higher throughput production rates as compared to traditional batch techniques,while maintaining reproducible control over microtissue composition and *** this review,we provide a comprehensive overview of the current approaches to engineer microtissues with a focus on the advantages of,and need for,the use of continuous processes to produce microtissues in large ***,an outlook is provided that outlines the required developments to enable large-scale microtissue fabrication using continuous processes.

关键词： Tissue engineering Micromaterials Microfluidics Upscaling Clinical translation Industrial translation

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Effect of climate change on seasonal monsoon in Asia and its impact on the variability of monsoon rainfall in Southeast Asia

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Geoscience Frontiers 2015年第6期6卷 817-823页

作者： Yen Yi loo Lawal Billa Ajit Singh School of Bioscience University of Nottingham Malaysia Campus School of Geography University of Nottingham Malaysia Campus

Global warming and climate change is one of the most extensively researched and discussed topical issues affecting the *** there are enough historical evidence to support the theory that climate change is a natural phenomenon,many research scientists are widely in agreement that the increase in temperature in the 20 th century is anthropologically *** associated effects are the variability of rainfall and cyclonic patterns that are being observed *** Southeast Asia the link between global warming and the seasonal atmospheric flow during the monsoon seasons shows varying degree of *** study investigates the impact of climate change on the seasonality of monsoon Asia and its effect on the variability of monsoon rainfall in Southeast *** comparison of decadal variation of precipitation and temperature anomalies before the 1970 s found general increases which were mostly *** beyond the 1970 s,global precipitation anomalous showed increases that almost corresponded with increases in global temperature anomalies for the same *** are frequent changes and a shift westward of the Indian summer *** precipitation is observed to be 70%below normal levels,in some areas the topography affects the intensity of *** shifting phenomenon of other monsoon season in the region are impacting on the variability of rainfall and the onset of monsoons in Southeast Asia and is predicted to delay for 15 days the onset of the monsoon in the *** variability of monsoon rainfall in the SEA region is observed to be decadal and the frequency and intensity of intermittent flooding of some areas during the monsoon season have serious consequences on the human,financial,infrastructure and food security of the region.

关键词： Climate change Temperature anomalies Precipitation anomalies Seasonal monsoons Rainfall variability Southeast Asia

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