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Polio eradication surveillance in s.i.Lanka,2019-2023

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Asian Pacific Journal of Tropical Medicine 2024年第6期17卷 268-272页

作者： M.A.Y.Fernando N.s.Madarasinghe C.Rangana N.Weerasinghe D.C.U.D.Weligamage J.i.Abeynayake Department of Medical Microbiology and immunology Faculty of MedicineUniversity of ColomboSri Lanka Department of Virology Medical Research InstituteColombo 08Sri Lanka Medical Research ins.i.ute Colombo 08Sri Lanka

Objective:To evaluate the polio laboratory surveillance carried out from January,2019 to May,2023 by the Polio Regional Reference Laboratory,s.i.***:This retrospective study analyzed all stool samples received under the acute flaccid paralysis(AFP)and immunodeficient vaccine-derived poliovirus(VDPV)surveillance at Polio Regional Reference Laboratory,s.i.Lanka from January,2019 to May,*** results of the tes.i.g methodologies were extracted from the laboratory data system,i.e.,poliovirus virus.i.olation,intra-typic differentiation/VDPV real time reverse transcriptase polymerase chain reaction(iTD/VDPV rRTPCR)and sequencing,along with the data on timing of reporting results,stool adequacy and *** was analyzed using descriptive ***:A total of 2141 stool samples from 1644 cases were received for AFP surveillance from s.i.Lanka(93.61%),Maldives(1.52%),and immunodeficient VDPV(4.86%)*** polioviruses(19/1644,1.15%)and non-polio enteroviruses(73/1644,4.44%)were isolated,while sabin-like 3 virus was detected in majority(12/19,63.15%)among the poliovirus *** polioviruses or circulating VDPVs were not detected among the *** all years of the study,the non-polio AFP detection rate was>1/100000 in children aged less than 15 years,whereas stool adequacy rate was>80%.All results were reported within 14 days of receipt,ensuring timely reporting as per global ***:The Polio Regional Reference Laboratory,s.i.Lanka plays a vital role in maintaining the polio-free status.i. the country through its robust laboratory surveillance,while adhering to the surveillance ***-detection of wild polioviruses and circulating VDPV during the study period reinforces the polio-free status.i. the country.

关键词： Poliovirus Polio laboratory surveillance Regional reference laboratory Polio eradication

Measurement of yields and angular distributions ofγ-quanta from the interaction of 14.1 MeV neutrons with oxygen,phosphorus,and sulfur

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Chinese Physics C 2024年第3期48卷 79-92页

作者： D.N.Grozdanov N.A.Fedorov s.B.Dabylova Yu.N.Kopatch i.N.Ruskov V.R.skoy T.Yu.Tretyakova C.Hramco P.i.Kharlamov G.V.Pampus.i. P.G.Filonchik A.V.Andreev Joint ins.i.ute for Nuclear Research(JiNR) DubnaRussia ins.i.ute for Nuclear Research and Nuclear Energy Bulgarian Academy of SciencesSofiaBulgaria Faculty of Physics Lomonosov Moscow State UniversityMoscowRussia L.N.Gumilyov Eurasian National University AstanaKazakhstan skobeltsyn ins.i.ute of Nuclear Physics Moscow State UniversityMoscowRussia ins.i.ute of Chemistry of Moldova ChisinauRepublic of Moldova Moscow ins.i.ute of Physics and Technology MoscowRussia

A study of the inelas.i. scattering of neutrons with an energy of 14.1 MeV on the nuclei of oxygen,phosphorus,and sulfur was performed at the TANGRA facility at JiNR(Dubna).The experiment aimed to refine exis.i.g data and obtain new data on the yields and angular distributions ofγ-quanta emitted by the studied nuclei due to neutron-induced nuclear reactions using the tagged neutron *** types of detector systems were used to registerγ-***γ-ray yields were measured using a high-purity germanium(HPGe)*** angular distributions ofγ-rays were obtained using a system of 18 s.i.tillation detectors based on bismuth germanite Bi_(4)Ge_(3)O_(12)(BGO)located around the *** performed experiments measured the yields of two transitions for the reaction of tagged neutrons with 16O,nine transitions for the reaction with ^(31)P,and nine transitions for the reaction with ^(32)s for the first *** angular anisotropy of theγ-radiation accompanying the inelas.i. scattering of neutrons with an energy of 14.1 MeV on ^(31)P nuclei was also measured for the first time.

关键词： tagged neutron method yields of gamma-quanta high-resolution gamma-spectrometry neutron-nuclear reactions neutron scattering

Tribological behavior of lubricant-impregnated porous polyimide

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Friction 2024年第4期12卷 711-725页

作者： Jinbang Li Ningning ZHOU Janet s.s.WONG school of Mechanical Engineering and Mechanics Ningbo UniversityNingbo 315211China Beijing Key Laboratory of Long-life Technology of Precise Rotation and Trans.i.sion Mechanisms Beijing Institute of Control EngineeringBeijing 100029China Department of Mechanical Engineering Imperial College LondonLondon SW72AZUK

Porous materials.i.pregnated with lubricants can be used in conditions where limited lubricant is *** this work,three porous polyimides(PPi)with different densities were ***(PAO)impregnated PPi(iPPi)discs were rubbed against steel and sapphire *** operando observations of the iPPi-sapphire contacts show that oil is released under an applied load,forming a meniscus around *** at the outlet is created at high s.i.ing *** amount of released oil increases with increasing PPi *** moduli,E*,es.i.ated based on the actual contact size show that trapped oil in iPPis contributes to load *** higher speeds,tribological rehydration of the contact occurs.i. low density iPPi,with that E*rises with *** high density PPis,high speeds give a constantly high E*which is limited by the viscoelas.i. properties of the PPi network and pos.i.ly the rate of oil *** of iPPi-steel contacts.i. governed by the mechanical properties of the PPi,the flow of the lubricant,and the roughness of the PPi *** low-and medium-density(highly porous,high roughness)PPis,large amount of oil is released,and lubrication is mainly via lubricant restricted in the contact in the pores and pos.i.ly tribological *** high density(low porosity)PPi,with lower roughness,hydrodynamic lubrication is achieved which gives the lowest *** results show that polymeric porous materials for effective lubrication require the optimization of its surface roughness,s.i.fness,oil flow,and oil retentions.

关键词： polyimide porous material friction mechanism polymer limited lubrication

Outcomes of long-acting injectable antipsychotics use in pregnancy:A literature review

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World Journal of Psychiatry 2024年第4期14卷 582-599页

作者： Ana V Pejčić srdjan M stefanović MilošN Milosavljević Vladimir s Janjić Marko M Folić Nevena D Folić Jovana Z Milosavljević Department of Pharmacology and Toxicology Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Department of Pharmacy Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Department of Clinical Pharmacology University Clinical Center KragujevacKragujevac 34000Serbia Department of Psychiatry Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Clinic for Psychiatry University Clinical Center KragujevacKragujevac 34000Serbia Center for Pharmaceutical and Pharmacological Research Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Department of Pediatrics Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Pediatric Clinic University Clinical Center KragujevacKragujevac 34000Serbia Department of Anatomy Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia

BACKGROUND Women with a history of serious psychotic disorders are at increased risk of disease relapse during ***-acting injectable(LAi)antipsychotics have been widely used to improve adherence and prevent relapse in patients with various severe psychotic disorders,but there is a lack of high-quality data from previous research on the safety of LAi antipsychotics during *** To summarize relevant data on maternal,pregnancy,neonatal,and developmental outcomes from published cases of LAi antipsychotic use in *** A literature search was performed through November 11,2023,using three online databases:PubMed/MEDLiNE,scopus,and Web of *** reports or case series that reported information about the outcomes of pregnancy in women who used LAi antipsychotics at any point in pregnancy,with available full texts,were *** statis.i.s,narrative summation,and tabulation of the extracted data were *** A total of 19 publications satis.i.d the inclusion criteria:3 case series,15 case reports,and 1 conference *** reported the outcomes of LAi antipsychotic use in 74 women and 77 *** use of secondgeneration LAi antipsychotics was reported in the majority(n=47;61.0%)of ***-generation LAi antipsychotics were administered during 30 pregnancies(39.0%).Most of the women(approximately 64%)had either satisfactory control of symptoms or no information about relapse,while approximately 12%of them had developed gestational diabetes mellitus.A minority of cases reported adverse outcomes such as s.i.lbirth,spontaneous abortion,preterm birth,low birth weight,congenital anomalies,and neurological manifestations.i. ***,there were no reports of negative long-term developmental *** Currently available data seem reassuring,but further well-designed studies are required to properly evaluate the risks and benefits of LAi antipsychotic use during pregnancy.

关键词： Antipsychotic agents Long-acting injectable Pregnancy Outcome Review

Prompt neutron emis.i.n in ^(250)No spontaneous fis.i.n associated with ground and isomeric state decays

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Chinese Physics C 2024年第6期48卷 112-117页

作者： R.s.Mukhin A.V.isaev A.V.Andreev M.L.Chelnokov V.i.Chepigin H.M.Devaraja i.N.izosimov A.A.Kuznetsova O.N.Malyshev A.G.Popeko Yu.A.Popov A.Rahmatinejad B.s.i.aubekov T.M.shneidman E.A.sokol A.i.s.i.ikhin M.s.Tezekbayeva M.A.Bychkov A.V.Yeremin O.Dorvaux B.Gall K.Kessaci K.Hauschild A.Lopez-Martens Joint ins.i.ute for Nuclear Research Dubna141980Russia Dubna state University Dubna141982Russia ins.i.ute of Nuclear Physics Almaty050032Kazakhstan L.N.Gumilyov Eurasian National University Astana010008Kazakhstan Kazan Federal University Kazan420008Russia Universitéde strasbourg CNRSStrasbourg67000France iJCLab IN2P3-CNRSUniversitéParis-SaclayOrsay91400France

The complete-fusion reaction^(204)Pb(^(48)Ca,2n)^(250)No was used to study two activities of^(250)No with dis.i.ct half-lives.A total of 1357 events were observed in the s.i.x neutron detection *** average number of neutrons emitted per spontaneous fis.i.n of^(250)No was determined to be(4.1±0.1).The unusually symmetrical shape of the prompt neutron multiplicity distribution was restored and presented for the first *** tests were performed to compare the prompt neutron multiplicity distributions associated with the ground state and K-isomer state decays.

关键词： spontaneous fis.i.n prompt neutrons actinide

Enhancing fatigue performance of AZ31 magnesium alloy components fabricated by cold metal transfer-based wire arc directed energy deposition through LPB

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Journal of Magnesium and Alloys 2024年第4期12卷 1638-1662页

作者： shambhu Kumar Manjhi s.i.anth Bontha A.s.s.Balan Department of Mechanical Engineering National Institute of Technology KarnatakaSurathkalSrinivasanagarMangaloreKarnataka 575025India

Cold Metal Transfer-Based Wire Arc Directed Energy Deposition(CMT-WA-DED)presents a promising avenue for the rapid fabrication of components crucial to automotive,s.i.building,and aerospace ***,the susceptibility to fatigue of CMT-WA-DED-produced AZ31 Mg alloy components has.i.peded their widespread adoption for critical load-bearing *** this study,a comprehensive inves.i.ation into the fatigue behaviour of WA-DED-fabricated AZ31 Mg alloy has been carried out and compared to commercially available wrought AZ31 *** findings.i.dicate that the as-deposited parts exhibit a lower fatigue life than wrought Mg alloy,primarily due to poor surface finish,tensile residual stress,porosity,and coarse grain microstructure inherent in the WA-DED *** Plas.i.ity Burnis.i.g(LPB)treatment is applied to mitigate these issues,which induce significant plas.i. deformation on the *** treatment resulted in a remarkable improvement of fatigue life by 42%,accompanied by a reduction in surface roughness,grain refinement and enhancement of compres.i.e residual stress ***,during cyclic deformation,WA-DED specimens exhibited higher plas.i.ity and dislocation density compared to both wrought and WA-DED+LPB specimens.A higher fraction of Low Angle Grain Boundaries(LAGBs.i. WA-DED specimens contributed to multiple crack initiation sites and convoluted crack paths,ultimately leading to premature *** contrast,wrought and WA-DED+LPB specimens displayed a higher percentage of High Angle Grain Boundaries(HAGBs),which hindered dislocation movement and resulted in fewer crack initiation sites and less complex crack paths,thereby extending fatigue *** findings underscore the effectiveness of LPB as a post-proces.i.g technique to enhance the fatigue performance of WA-DED-fabricated AZ31 Mg alloy *** study highlights the importance of LPB surface treatment on AZ31 Mg components produced by CMT-WA-DED to remove surface d

关键词： Wire arc additive manufacturing AZ31 Mg alloy Low plas.i.ity burnis.i.g Low cycle fatigue test strain amplitude

Evolution of Viral Load in Patients.i.fected with HiV-1 at Point G University Hos.i.al

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Open Journal of Medical Microbiology 2024年第1期14卷 66-76页

作者： A. Maiga D. Kone D. M. Coulibaly Ag M. Baraika A. Traore s. s. Diakite i. i. Maiga i. Konate A. i. Maiga Faculty of Medicine and Odontostomatology of Bamako (FMOs) University of Science of Technical and Technology De Bamako Bamako Mali Laboratory of Medical Biology and Hos.i.al Hygiene of Point-G University Hos.i.al Bamako Mali Faculty of Pharmacy of Bamako (FaPh) University of Science of Technical and Technology De Bamako Bamako Mali Laboratory of the Luxembourg Mother-Child Hos.i.al Bamako Mali National ins.i.ute of Public Health Bamako Mali National ins.i.ute for Training in Health s.i.nces Bamako Mali Laboratory of the Kati University Hos.i.al Center Bamako Mali infectious and Tropical Diseases Department of Point-G University Hos.i.al Bamako Mali Laboratory of CHU Gabriel Touré Bamako Mali

introduction: HiV, the human immunodeficiency virus, is the etiological agent of acquired immunodeficiency syndrome (AiDs). The aim of this study was to assess the evolution of the viral load in patients under treatment. Methodology: This was a study carried out from July 2017 to June 2022 at the Point G University Hos.i.al laboratory. The determination of the viral load of patients was carried out by PCR on the ABOTT M2000sp/rt platform. Results: A total of 129 patients.i.fected with HiV-1, aged 19 to 72 years with a mean age of 40.05 years ± 10.71;all on antiretroviral chemotherapy. The female gender predominated among our patients. The most common treatment regimen was 2iNTi + 1iNNTi with 72.9% followed by 2iNTi + 1iNi with 13.2%. As for the combinations of molecules, the combination TDF + 3TC + EFV and TDF + 3TC + DTG predominated, respectively 65.1% and 13.2%. 89.9% of our patients had undetectable viremia after 12 months of treatment (p ith an average viral load which had evolved from 681315.65 copies/ml ± 1616908.484 to M0 at 5742.36 copies /ml ± 35756.883 at M12 (p Conclusion: Generally speaking, antiretroviral treatment had contributed to controlling viral loads, however the therapeutic combination TDF + 3TC + DTG had made it pos.i.le to obtain more patients with undetectable viremia instead.

关键词： HiV-1 Treatment Viral Load Point G University Hos.i.al

Ren-integrable and ren-symmetric integrable systems

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Communications.i. Theoretical Physics 2024年第3期76卷 62-69页

作者： s Y Lou school of Physical s.i.nce and Technology Ningbo UniversityNingbo315211China

A new type of symmetry,ren-symmetry,describing anyon physics and corresponding topological physics.i. ***-symmetry is a generalization of super-symmetry which is widely applied in super-symmetric physics such as super-symmetric quantum mechanics,super-symmetric gravity,super-symmetric string theory,super-symmetric integrable systems and so *** and Grassmann numbers are,in some sense,dual conceptions,and it turns out that these conceptions coincide for the ren situation,that is,a similar conception of ren-number(R-number)is devised for *** particular,some basic results of the R-number and ren-symmetry are exposed which allow one to derive,in principle,some new types of integrable systems.i.cluding ren-integrable models and ren-symmetric integrable *** examples of ren-integrable KdV-type systems and ren-symmetric KdV equations are explicitly given.

关键词： symmetries integrable systems anyon physics extended supersymmetry ren-symmetry

AutoRhythmAi: A Hybrid Machine and Deep Learning Approach for Automated Diagnosis of Arrhythmias

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Computers, Materials & Continua 2024年第2期78卷 2137-2158页

作者： s.Jayanthi s.Prasanna Devi Department of Computer s.i.nce and Engineering SRM Institute of Science and Technology-Vadapalani CampusChennaiTamil NaduIndia

in healthcare,the persistent challenge of arrhythmias,a leading cause of global mortality,has sparked extensive research into the automation of detection using machine learning(ML)***,traditional ML and AutoML approaches have revealed their limitations,notably regarding feature generalization and automation *** glaring research gap has motivated the development of AutoRhythmAi,an innovative solution that integrates both machine and deep learning to revolutionize the diagnosis of *** approach encompasses two dis.i.ct pipelines tailored for binary-class and multi-class arrhythmia detection,effectively bridging the gap between data preproces.i.g and model *** validate our system,we have rigorously tested AutoRhythmAi using a multimodal dataset,surpas.i.g the accuracy achieved using a single dataset and underscoring the robustness of our *** the first pipeline,we employ signal filtering and ML algorithms for preproces.i.g,followed by data balancing and split for *** second pipeline is dedicated to feature extraction and clas.i.ication,utilizing deep learning ***,we introduce the‘RRi-convoluted trans-former model’as a novel addition for binary-class *** ensemble-based approach then amalgamates all models,considering their respective weights,resulting in an optimal model *** our study,the VGGRes Model achieved impres.i.e results.i. multi-class arrhythmia detection,with an accuracy of 97.39%and firm performance in precision(82.13%),recall(31.91%),and F1-score(82.61%).in the binary-class task,the proposed model achieved an outstanding accuracy of 96.60%.These results highlight the effectiveness of our approach in improving arrhythmia detection,with notably high accuracy and well-balanced performance metrics.

关键词： Automated machine learning neural networks deep learning arrhythmias