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Synchronous resection of esophageal cancer and other organ malignancies: A systematic review

World Journal of Gastroenterology 2019年第26期25卷 3438-3449页

作者： Dimitrios Papaconstantinou Diamantis I Tsilimigras Dimitrios Moris Adamantios Michalinos Aikaterini Mastoraki efstratia mpaili Natasha Hasemaki Anargyros Bakopoulos Dimitrios Filippou Dimitrios Schizas Third Department of Surgery National and Kapodistrian University of AthensAttikon University HospitalAthens 12462Greece Department of Surgery Division of Surgical OncologyThe Ohio State University Wexner Medical Center and James Cancer Hospital and Solove Research InstituteColumbusOH 43210United States Department of Surgery Duke University Medical CenterDurhamNC 27710United States Department of Anatomy European University of CyprusNicosia 2404Cyprus First Department of Surgery National and Kapodistrian University of AthensLaikon General HospitalAthens 11527Greece Department of Anatomy and Surgical Anatomy National and Kapodistrian University of AthensMedical SchoolAthens 11527Greece

BACKGROUND Neoplasms arising in the esophagus may coexist with other solid organ or gastrointestinal tract neoplasms in 6%to 15%of *** of both tumors synchronously or in a staged procedure provides the best chances for long-term *** resection of both esophageal and second primary malignancy may be feasible in a subset of patients;however,literature on this topic remains rather *** To analyze the operative techniques employed in esophageal resections combined with gastric,pancreatic,lung,colorectal,kidney and liver resections and define postoperative outcomes in each *** We conducted a systematic review according to PRISMA *** searched the Medline database for cases of patients with esophageal tumors coexisting with a second primary tumor located in another organ that underwent synchronous resection of both *** English language articles deemed eligible for inclusion were accessed in full *** criteria included:(1)Hematological malignancies;(2)Head/neck/pharyngeal neoplasms;(3)Second primary neoplasms in the esophagus or the gastroesophageal junction;(4)Second primary neoplasms not surgically excised;and(5)Preclinical *** regarding the operative strategy employed,perioperative outcomes and longterm outcomes were extracted and analyzed using descriptive *** The systematic literature search yielded 23 eligible studies incorporating a total of 117 *** these patients,71%had a second primary neoplasm in the *** who underwent total gastrectomy had a reconstruction using either a colonic(n=23)or a jejunal(n=3)conduit while for those who underwent gastric preserving resections(i.e.,non-anatomic/wedge/distal gastrectomies)a conventional gastric pull-up was ***,in cases of patients who underwent esophagectomy combined with pancreaticoduodenectomy(15%of the cohort),the decision to preserve part of the stomach or not dictated the reconstruction met

关键词： Esophagectomy Esophageal neoplasm Second primary Multiple primary Concurrent neoplasms Management

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