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热休克T细胞中mRNA的表达

生物化学杂志 1987年第2期 131-138页

作者：沈珝琲 Vincent G.Allfrey edward M.Johnson 中国医学科学院基础医学研究所美国洛克菲勒大学美国洛克菲勒大学北京纽约纽约

富集的人外周血T淋巴细胞经40—42℃保温（热休克）可诱导产生90kd和71kd的两种主要热休克蛋白（HSP）,此外,62和34kd HSP也可在不同条件下诱导。从不同处理的T淋巴细胞中提取mRNA并在免网织细胞裂解液系统中进行体外转译,显示出相同的... 详细信息

富集的人外周血T淋巴细胞经40—42℃保温（热休克）可诱导产生90kd和71kd的两种主要热休克蛋白（HSP）,此外,62和34kd HSP也可在不同条件下诱导。从不同处理的T淋巴细胞中提取mRNA并在免网织细胞裂解液系统中进行体外转译,显示出相同的主要HSP。其中71和62kdHSP不仅在升温时还可在低温（4℃）下诱导,表明淋巴细胞中几种主要HSP的诱导机制不完全相同。比较l-35S-Met参入实验和体外转译的结果提示淋巴细胞中HSP基因表达主要在转录水平调控。

关键词：热休克蛋白 mRNA 基因表达

认识风湿热和风心病的新努力——关于链球菌和人类宿主的概念

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岭南心血管病杂志 2001年第6期7卷 413-413页

作者： edward l.Kaplan 刘小青 Universityof Minnesota Medical SchoolMinneapolis Minnesota USA

虽然对A组β溶血性链球菌与风湿热的关系已认识半个多世纪,但对这个关系的许多重要的问题尚未完全确定。

关键词：风湿热风湿性心脏病链球菌宿主

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Wilderness medicine

World Journal of Emergency Medicine 2014年第1期5卷 5-15页

作者： Douglas G.Sward Brad l.Bennett Department of Emergency Medicine University of Maryland School of Medicine Hyperbaric Medicine Shock Trauma Center Military & Emergency Medicine Department F. Edward Hébert School of Medicine Uniformed Services University of the Health Sciences

BACKGROUND: Human activity in wilderness areas has increased globally in recent decades, leading to increased risk of injury and illness. Wilderness medicine has developed in response to both need and ***: The field of wilderness medicine encompasses many areas of interest. Some focus on special circumstances(such as avalanches) while others have a broader scope(such as trauma care). Several core areas of key interest within wilderness medicine are discussed in this ***: Wilderness medicine is characterized by remote and improvised care of patients with routine or exotic illnesses or trauma, limited resources and manpower, and delayed evacuation to definitive care. Wilderness medicine is developing rapidly and draws from the breadth of medical and surgical subspecialties as well as the technical fields of mountaineering, climbing, and diving. Research, epidemiology, and evidence-based guidelines are evolving. A hallmark of this field is injury prevention and risk mitigation. The range of topics encompasses high-altitude cerebral edema, decompression sickness, snake envenomation, lightning injury, extremity trauma, and gastroenteritis. Several professional societies, academic fellowships, and training organizations offer education and resources for laypeople and health care ***: The future of wilderness medicine is unfolding on multiple fronts: education, research, training, technology, communications, and environment. Although wilderness medicine research is technically difficult to perform, it is essential to deepening our understanding of the contribution of specific techniques in achieving improvements in clinical outcomes.

关键词： Wilderness medicine High-altitude sickness Dive medicine Envenomation Trauma Hyperthermia Hypothermia Frostbite Avalanche Combat injuries Search and rescue Travel medicine Disaster medicine

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智慧七柱上

丛书名：探险与旅行经典文库

2002年

作者：（英）汤玛士·爱德华·劳伦斯（Thomas edward lawrence）蔡悯生译

本书主要内容包括：濒临疯狂的两面人；所谓的阿拉伯；黑白的信仰；土耳其伺机崛起；美索不达米亚；航向沙乌地等。

ISBN: (纸本)7500646399

本书主要内容包括：濒临疯狂的两面人；所谓的阿拉伯；黑白的信仰；土耳其伺机崛起；美索不达米亚；航向沙乌地等。

关键词：游记作品集英国现代

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拜占庭帝国大战略

2018年

作者： (美)爱德华·N.勒特韦克(edward N. luttwak)

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膝关节软骨缺损的微骨折软骨面重建手术技术

骨科动态 2007年第1期3卷 49-57页

作者： KAI MITHOEFER RIlEY J. WIllIAMS Ⅲ RUSSEll F. WARREN HOllIS G. POTTER CHRISTOPHER R. SPOCK edward C. JONES THOMAS l. WICKIEWICZ ROBERT G. MARX 张春礼（译） Investigtion performed at the Institute for Cartilage Repair Hospital for Special Surgery New York NY The original scientific article in which the surgical technique was presented was published in JBJS Vol. 87-A pp 1911-1920 September 2005 西安第四军医大学西京医院骨科 710032

背景：微骨折是常用于修复膝关节软骨病损的技术。尽管该项技术应用很普遍，但有关远期临床结果的信息仍很有限。本研究的目的是找出该项软骨修复技术临床疗效的影响因素。方法：采用微骨折技术治疗48例膝关节稳定、股骨髁孤立、全层软... 详细信息

背景：微骨折是常用于修复膝关节软骨病损的技术。尽管该项技术应用很普遍，但有关远期临床结果的信息仍很有限。本研究的目的是找出该项软骨修复技术临床疗效的影响因素。方法：采用微骨折技术治疗48例膝关节稳定、股骨髁孤立、全层软骨缺损并有症状的患者。最短随访24个月，采用公认的疗效评分和主观临床评级及软骨敏感NRI扫描对患者的结果进行前瞻性评估。结果：末次随访时，膝关节功能优、良32例（67％），可12例（25％），差4例（8％）。日常活动评分、国际膝关节信息委员会（IKDC）评分、SF-36体格检查评分术后均有显著性增加（p〈0.05），体重指数（BM）较低，则日常活动评分SF-36体格检查评分较高，BMI〉30kg/m^2则效果最差。术前症状时间少于12个月，则日常活动评分显著增加（p〈0.05）。24膝中MRI证实缺损填充，修复良好13例（54%），中等填充7例（29%），填充不良4例（17%），填充度与膝关节功能评分相关。全部缺损填充良好的膝关节，功能均有改善，而填充不良的关节，功能改善有限，且24个月后功能评分下降。结论：微骨折技术修复膝关节软骨病损在最短2年的随访期间功能有显著改善，软骨缺损填充良好，BMI较低，术前症状期短者可取得最佳短期疗效；高BMI对短期疗效有负面影响，软件缺损填充不良则短期疗效较差。

关键词：膝关节软骨缺损软骨面重建微骨折手术技术膝关节软骨病损功能评分膝关节功能 SF-36

Extraction of Soil Boron for Predicting Its Availability to Plants

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Pedosphere 1991年第2期1卷 137-144页

作者： lIREN－AN U.C.GUPTA DepartmentofSoilScience ZhejiangAgriculturalUniversityHangzhou310029（China） ResearchBranch ResearchS

Field and greenhouse studies were conducted in Prince edward Island (P.E.I.) on soybean (Glycine max(l.) Merr.), red clover (Trifolium pratense l.),alfalfa (Medicago sativa l.), and rutabaga (Brassica napobrassica,Mill).Plant B concentrations were compared to soil B extracted by hot-water,0.05 M HC1,1.5 M CH3COOH and 0.01 M *** r values for extractable soil B *** B were:hot water (0.67),0.05 M HCl(0.82),1.5M CH3COOH(0.78) and hot 0.01 M CaCl2(0.61).Results of soil B from the 0.05 M HCl extracts were generally found to give the best correlation and linear regression among the four extractants tested for predicting the availability of B to the ***,the 0.05 M HCl proved to be superior to hot water extraction and is recommended for predicting the available B status of the acid soils of *** probability of error with 0.05 M HCl is less since it is shaken for a fixed period of time as opposed to subjective error which could be caused in monitoring the boiling time using hot water.

关键词：土壤硼提取植物有效性预测

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慢性胰腺炎患者施胰腺空肠吻合术的远期效果

吉林医学 1988年第6期 374-374页

作者： edward l.Bradley 张淑杰

爱德华·l·布拉德利认为解除慢性胰腺炎和胰管扩张患者的顽固性疼痛,胰腺空肠吻合术可取得良好的效果。但是,有少数研究者对这种手术初期的效果能否随时间推移而降低产生疑问,且有人提出慢性胰腺炎患者的疼痛可以自发解除,使人们在治... 详细信息

爱德华·l·布拉德利认为解除慢性胰腺炎和胰管扩张患者的顽固性疼痛,胰腺空肠吻合术可取得良好的效果。但是,有少数研究者对这种手术初期的效果能否随时间推移而降低产生疑问,且有人提出慢性胰腺炎患者的疼痛可以自发解除,使人们在治疗这些患者时对手术的作用产生了某些疑虑。为

关键词：胰尾空肠吻合术疼痛胰管扩张慢性胰腺炎慢性复发性胰腺炎胰腺空肠吻合术患者

Alterations in Caspase-3 in Juvenile Rats Treated Neonatally with Domoic Acid

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Journal of Behavioral and Brain Science 2016年第9期6卷 357-363页

作者： Mark A. Robbins Catherine l. Ryan Tracy A. Doucette Department of Biology University of Prince Edward Island Charlottetown Canada Department of Psychology University of Prince Edward Island Charlottetown Canada

The clinical presentation of schizophrenia involves a variety of symptoms, which in many cases include hallucinations and delusions. Experimentally revealed alterations in both pre-pulse inhibition (PPI) and latent inhibition (lI) are also apparent in individuals afflicted with this disorder. Many have speculated that altered synaptic connections are, in part, responsible for this subset of behavioral abnormalities. We have previously reported that neonatal chronic low-dose injections of domoic acid (DOM) produce adult rats with deficits in PPI and lI. The current study was conducted to determine whether this toxin-treatment would alter the degree of apoptosis occurring in the developing brain. Results revealed significant decreases in caspase-3 within the right prelimbic cortex (Prl) in both male and female DOM-treated rats suggesting that even modest alterations in glutamate (Glu) signaling during critical periods of central nervous system (CNS) maturation will modify ontogenetic processes in the prefrontal cortex (PFC) of the juvenile rat.

关键词： Neonatal Rat Domoic Acid Prefrontal Cortex Apoptosis Caspase-3