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A systematic review of robot-assisted partial nephrectomy outcomes for advanced indications:Large tumors(cT2-T3),solitary kidney,completely endophytic,hilar,recurrent,and multiple renal tumors

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Asian Journal of Urology 2023年第4期10卷 390-406页

作者： Savio Domenico Pandolfo Clara Cerrato Zhenjie Wu Antonio Franco Francesco Del Giudice Alessandro Sciarra Paolo Verze Giuseppe Lucarelli Ciro Imbimbo Sisto Perdonà edward e.cherullo Francesco Porpiglia Ithaar H.Derweesh Riccardo Autorino Department of Urology Rush University Medical CenterChicagoILUSA Department of Neurosciences Reproductive Sciences and Odontostomatology“Federico II”UniversityNaplesItaly Department of Urology University of VeronaVeronaItaly Department of Urology Changhai HospitalNaval Medical UniversityShanghaiChina european Association of Urology(eAU)Young Academic Urologists(YAU)Renal Cancer Working Group Arnhemthe Netherlands Department of Urology Sant’Andrea HospitalLa Sapienza UniversityRomeItaly Department of Maternal-Infant and Urologic Sciences La Sapienza UniversityPoliclinico Umberto I HospitalRomeItaly Department of Medicine and Surgery Scuola Medica SalernitanaUniversity of SalernoFiscianoItaly Department of emergency and Organ Transplantation-Urology Andrology and Kidney Transplantation UnitUniversity of BariBariItaly Department Uro-Gynecology IRCCS G.Pascale FoundationNaplesItaly Department of Urology San Luigi Gonzaga HospitalUniversity of TurinOrbassanoItaly Department of Urology University of California San DiegoLa JollaCAUSA

Objective:Robot-assisted partial nephrectomy(RAPN)has become widely used for treatment of renal cell carcinoma and it is expanding in the field of complex renal *** aim of this systematic review was to analyze outcomes of RAPN for completely endophytic renal masses,large tumors(cT2-T3),renal cell carcinoma in solitary kidney,recurrent tumors,completely endophytic and hilar masses,and simultaneous and multiple ***:A comprehensive search in the PubMed,Scopus,Web of Science,and Cochrane Central Register of Controlled Trials databases was performed in December 2022 for english language *** primary endpoint was to evaluate the role of RAPN in the setting of each category of complex renal masses *** secondary endpoint was to evaluate the surgical and functional ***:After screening 1250 records,43 full-text manuscripts were selected,comprising over 8500 *** and thirteen studies reported data for endophytic and hilar renal masses,*** and three studies reported outcomes for cT2-T3 and solitary kidney patients,*** studies focused on redo-RAPN for recurrent *** studies investigated simultaneous bilateral renal masses and five reports focused on multiple tumor excision in ipsilateral ***:Over the past decade,evidence supporting the use of RAPN for the most challenging nephron-sparing surgery indications has continuously *** limitations remain including study design and lack of detailed long-term functional and oncological outcomes,the adoption of RAPN for the included advanced indications is associated with favorable surgical outcomes with good preservation of renal function without compromising the oncological ***,a higher likelihood of complication might be expected when facing extremely challenging ***,none of these indications should be considered per se an exclusion criterion for performing ***,a risk-adapted approach s

关键词： Robot-assisted partial nephrectomy Complex renal mass Solitary kidney Larger tumors(cT2-T3) endophytic and hilar mass Recurrent tumor Simultaneous and multiple tumor

Robotics in genital gender-affirming surgery

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Plastic and Aesthetic Research 2023年第1期10卷 74-82页

作者： Brielle Weinstein Henry Govekar edward cherullo Kristin M.Jacobs Loren Schechter Department of Surgery Division of Plastic and Reconstructive SurgeryRush University Medical CenterChicagoIL 60612USA Department of Surgery Division of Colorectal SurgeryRush University Medical CenterChicagoIL 60612USA Department of Urology Rush University Medical CenterChicagoIL 60612USA Department of Surgery Division of Plastic and Reconstructive SurgeryDepartment of Obstetrics and GynecologyRush University Medical CenterChicagoIL 60612USA

Gender-affirming genital surgery includes a constellation of pelvic procedures that can help feminize or masculinize the *** advances in robotic surgery can aid surgical access to and visualization of the pelvis,thereby facilitating certain *** this scoping review,we will discuss the developing role of the robot in genital affirming genital ***,techniques,and outcomes using the robot in both feminizing and masculinizing genital procedures will be reviewed.

关键词： Robotic surgery gender affirming surgery vaginoplasty peritoneal vaginoplasty intestinal vaginoplasty metoidioplasty colpectomy vaginectomy phalloplasty

Neural Network-Based Second Order Reliability Method(NNBSORM)for Laminated Composite Plates in Free Vibration

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Computer Modeling in engineering & Sciences 2018年第4期115卷 105-129页

作者： Mena e.Tawfik Peter L.Bishay edward e.Sadek Aerospace engineering Department Faculty of EngineeringCairo UniversityEgypt Mechanical and Aerospace engineering Department Rutgersthe State University of New JerseyNew BrunswickNJUSA Mechanical engineering Department College of Engineering and Computer ScienceCalifornia State UniversityNorthridgeCAUSA.

Monte Carlo Simulations(MCS),commonly used for reliability analysis,require a large amount of data points to obtain acceptable accuracy,even if the Subset Simulation with Importance Sampling(SS/IS)methods are *** Second Order Reliability Method(SORM)has proved to be an excellent rapid tool in the stochastic analysis of laminated composite structures,when compared to the slower MCS ***,SORM requires differentiating the performance function with respect to each of the random variables involved in the *** most suitable approach to do this is to use a symbolic solver,which renders the simulations very slow,although still faster than ***,the inability to obtain the derivative of the performance function with respect to some parameters,such as ply thickness,limits the capabilities of the classical *** this work,a Neural Network-Based Second Order Reliability Method(NNBSORM)is developed to replace the finite element algorithm in the stochastic analysis of laminated composite plates in free *** of the ability to obtain expressions for the first and second derivatives of the NN system outputs with respect to any of its inputs,such as material properties,ply thicknesses and orientation angles,the need for using a symbolic solver to calculate the derivatives of the performance function no longer *** proposed approach is accordingly much faster,and easily allows for the consideration of ply thickness *** present analysis showed that dealing with ply thicknesses as random variables results in 37%increase in the laminate’s probability of failure.

关键词： Reliability analysis artificial neural network composite laminates subset simulation importance sampling Monte Carlo

The molecular basis of hypertrophic scars

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Burns & Trauma 2016年第1期4卷 1-12页

作者： Zhensen Zhu Jie Ding edward e.Tredget Wound Healing Research Group Division of Plastic and ReconstructiveSurgeryUniversity of AlbertaEdmontonAlbertaCanada Department of Burn and Reconstructive Surgery 2nd AffiliatedHospital of Shantou University Medical CollegeShantouGuangdongChina. Wound Healing Research Group Division of Plastic and ReconstructiveSurgeryUniversity of AlbertaEdmontonAlbertaCanada Wound Healing Research Group Division of Plastic and ReconstructiveSurgeryUniversity of AlbertaEdmontonAlbertaCanada Division of PlasticSurgery Department of SurgeryUniversity of AlbertaEdmontonAlbertaCanada.

Hypertrophic scars(HTS)are caused by dermal injuries such as trauma and burns to the deep dermis,which are red,raised,itchy and *** can cause cosmetic disfigurement or contractures if craniofacial areas or mobile region of the skin are *** wound healing with more extracellular matrix deposition than degradation will result in HTS *** review will introduce the physiology of wound healing,dermal HTS formation,treatment and difference with keloids in the skin,and it also review the current advance of molecular basis of HTS including the involvement of cytokines,growth factors,and macrophages via chemokine pathway,to bring insights for future prevention and treatment of HTS.

关键词： Hypertrophic scars Animal model Cytokines Growth factors Macrophages Stromal cell-derived factor 1/CXCR4 signaling

Mini-Review:Green sustainable processes using supercritical fluid carbon dioxide

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Journal of environmental Sciences 2009年第6期21卷 720-726页

作者： RAMSeY edward University of Science and Technology Liaoning

environmentally benign carbon dioxide offers significant potential in its supercritical fluid phase to replace current reliance on a range of hazardous, relatively expensive and environmentally damaging organic solvents that are used on an extensive global basis. The unique combination of the physical properties of supercritical fluids are being exploited and further researched to continue the development and establishment of high efficiency, compact plant to provide energy and water efficient manufacturing processes. This mini-review is focused on the use and potential applications of supercritical fluid carbon dioxide for a selected range of key and emerging industrial processes as a sustainable alternative to totally eliminate or greatly reduce the requirement of numerous conventional organic solvents. examples of the industries include： chemical extraction and purification, synthetic chemical reactions including polymerization and inorganic catalytic processes. Biochemical reactions involving enzymes, particle size engineering, textile dyeing and advanced material manufacture provide further illustrations of vital industrial activities where supercritical fluid technology processes are being implemented or developed. Some aspects relating to the economics of sustainable supercritical fluid carbon dioxide processes are also considered.

关键词： supercritical extraction synthesis catalysis enzymes polymerization particles dyeing

Understanding Contaminant Veins in Squeeze Casting and Semi-solid Metalworking Processes

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特种铸造及有色合金 2003年第z1期23卷 230-234,238页

作者： edward J. Vinarcik, P.e. engineer Voctorie Co.8218 Medicine Bow Run Fort WayreIdiana 46825 U.S A

When commercializing the semi-solid metalworking processes, component producers looked to conventional die-casting to identify potential defects and control component quality. Several defects were expected including cold shuts, cold flows, flash, drags, warping, and gas entrapment, just to name a few. efforts were taken to avoid these defects. A new defect type, contaminant veins, has surfaced unique to semi-solid metalworking. Although, semi-solid metalworking has proven to be successful, component producers have been reluctant to report defects for fear of giving this emerging processes a bad reputation. Nonetheless, this defect must be understood to avoid future problems.

关键词： Contaminant Veins Squeeze Casting Semi-solid Casting

emerging Jasmonate Transporters

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Molecular Plant 2017年第5期10卷 659-661页

作者： Chi Tam Nguyen enrico Martinoia edward e. Farmer Department of Plant and Microbial Biology University of Zurich Zollikerstrasse 107 8008 Zurich Switzerland

Jasmonic acid （JA） and methyl jasmonate （MeJA） are highly mobile and, when applied to intact plants,, these compounds powerfully modulate gene expression. Moreover, activation of jasmonate-responsive genes usually occurs in tissues distal to the treatments. It therefore comes as no surprise that there are jasmonate transporters; these proteins are only now emerging and their discovery is important for a number of reasons. Firstlv.

关键词： emerging Jasmonate Transporters

Optimal decentralized control of large scale systems

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Control Theory and Technology 2016年第4期14卷 287-313页

作者： Xiao Qi SHI Daniel e. DAVISON Raymond KWONG edward J. DAVISON Systems Control Group Department of Electrical and Computer Engineering University of Toronto Ontario Canada MSS 3G4 Department of electrical and Computer engineering University of Waterloo Ontario Canada N2L 3G1

This paper presents a new optimized decentralized controller design method for solving the tracking and disturbance rejection problems for large-scale linear time-invariant systems, using only low-order decentralized controllers. To illustrate the type of results which can be obtained using the new optimized decentralized control design method, the control of a large flexible space structure is studied and compared with the standard centralized LQR-observer controller. The order of the resultant decentralized controller is much smaller than that of the standard centralized LQR-observer controller. The proposed controller also has certain fail-safe properties and, in addition, it can be five orders of magnitude more robust than the standard LQR-observer controller based on their real stability radii. The new decentralized controller design method is applied to a large flexible space structure system with 5 inputs and 5 outputs and of order 24.

关键词： Decentralized control multivariable control PID control robustness optimization large-scale systems flexiblestructures

Immune cell interplay in colorectal cancer prognosis

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World Journal of Gastrointestinal Oncology 2015年第10期7卷 221-232页

作者： Samuel e Norton Kirsten A Ward-Hartstonge edward S Taylor Roslyn A Kemp Department of Microbiology and Immunology University of Otago

The immune response to colorectal cancer has proven to be a reliable measure of patient outcome in several studies. However, the complexity of the immune response in this disease is not well understood, par-ticularly the interactions between tumour-associated cells and cells of the innate and adaptive immune system. This review will discuss the relationship betweencancer associated fibroblasts and macrophages, as well as between macrophages and T cells, and demonstrate how each population may support or prevent tumour growth in a different immune environment.

关键词： Colorectal cancer neoplasms Fibroblasts Immune sys