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Integrating geochemical(surface waters, stream sediments)and biological(diatoms) approaches to assess AMD environmental impact in a pyritic mining area： Aljustrel(Alentejo, Portugal)

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Journal of Environmental Sciences 2016年第4期28卷 215-226页

作者： Ana Teresa Luís Nuno Duraes SaloméFernandes Pinheiro de Almeida eduardo ferreira da silva University of Aveiro Department of GeosciencesGeoBioTec--GeobiosciencesGeotechnologies and Geoengineering Research CenterCampus de Santiago3810-193 AveiroPortugal University of Aveiro Department of BiologyGeoBioTec--GeobiosciencesGeotechnologies and Geoengineering Research CenterCampus de Santiago3810-193 AveiroPortugal Centro de Ciencias do Mar CCMARUniversidade do AlgarveCampus de Gambelas8005-139 FaroPortugal

Aljustrel mines were classified as having high environmental hazard due to their large tailings volume and high metal concentrations in waters and *** assess acid mine drainage impacted systems whose environmental conditions change quickly,the use of biological indicators with short generation time such as diatoms is *** study combined geochemical and diatom data,whose results were highlighted in 3 groups：Group 1,with low p H（1.9–5.1）and high metal/metalloid（Al,As,Cd,Co,Cu,Fe,Mn,Ni,Pb,Zn;0.65–1032 mg/L）and SO4（405–39124 mg/L）*** acidophilic species,Pinnularia aljustrelica,was perfectly adapted to the adverse conditions;in contrast,teratological forms of Eunotia exigua were found,showing that metal toxicity affected this *** low availability of metals/metalloids in sediments of this group indicates that metals/metalloids of the exchangeable fractions had been solubilized,which in fact enables metal/metalloid diatom uptake and consequently the occurrence of teratologies;Group 2,with sites of near neutral p H（5.0–6.8）and intermediate metal/metalloid（0.002–6 mg/L）and SO4（302–2179 mg/L）concentrations;this enabled the existence of typical species of uncontaminated streams（Brachysira neglectissima,Achnanthidium minutissimum）;Group 3,with samples from unimpacted sites,showing low metal/metalloid（0–0.8 mg/L）and SO4（10–315 mg/L）concentrations,high pH（7.0–8.4）and Cl contents（10–2119 mg/L）and the presence of brackish to marine species（Entomoneis paludosa）.For similar conditions of acidity,differences in diversity,abundance and teratologies of diatoms can be explained by the levels of metals/metalloids.

关键词： Surface waters Stream sediments Diatoms Metals/metalloids AMD Teratologies

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Assembly structures of coastal woody species of eastern South America:Patterns and drivers

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Plant Diversity 2024年第5期46卷 611-620页

作者： eduardo Vinícius da silva Oliveira Myrna Friederichs Landim Sidney F.Gouveia Graduate Program in Ecology and Conservation Federal University of SergipeSão CristovãoSergipeBrazil National Institute of Science and Technology Ecology Evolution and Conservation of Biodiversity(INCT-EECBio)GoiâniaGoiasBrazil Department of Biology Federal University of SergipeSão CristóvãoSergipeBrazil Department of Ecology Federal University of SergipeSão CristóvãoSergipeBrazil

Tropical regions have provided new insights into how ecological communities are *** dry coastal communities,water stress has been hypothesized to determine plant assembly structure by favoring preadapted lineages from neighboring ecosystems,consistent with functional ***,it is unclear whether this hypothesis is sufficient to explain how coastal communities in tropical ecosystems are ***,we test whether water stress or other factors drive community assembly in woody plant communities across the coastal zone of Brazil,a tropical *** characterized functional and phylogenetic structures of these communities and determined the underlying environmental factors(e.g.,water stress,historical climate stability,edaphic constraints,and habitat heterogeneity)that drive their community *** of coastal woody species show geographically varied patterns,including stochastic arrangements,clustering,and overdispersion of species relative to their traits and phylogenetic *** complexity,water vapor pressure,and soil nutrient availability best explained the gradient in the functional *** deficit,water vapor pressure,and soil organic carbon were the best predictors of variation in phylogenetic *** results support the water-stress conservatism hypothesis on functional and phylogenetic structure,as well as the effect of habitat heterogeneity on functional structure and edaphic constraints on functional and phylogenetic *** effects are associated with increased phenotypic and phylogenetic divergence of woody plant assemblages,which is likely mediated by abiotic filtering and niche opportunities,suggesting a complex pattern of ecological assembly.

关键词： Brazil Completeness Clustering Restinga vegetation Water constraints

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How far have we come?Review of main public policies to reduce landslide impacts in Brazil

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Journal of Mountain Science 2024年第9期21卷 2891-2904页

作者： Bianca Carvalho VIEIRA Tiago damas MARTINS Telma Mendes da silva Joséeduardo BONINI Department of Geography University of São PauloAvenida Professor Lineu Prestes 05508-000Brazil Cities Institute Federal University of São PauloAvenida Jacu-Pêssego 08260-001Brazil Department of Geography Federal University of Rio de JaneiroAvenida Athos da Silveira Ramos 21941-916Brazil

During the rainy season in Brazil,landslides can have catastrophic consequences,including loss of life,damage to urban infrastructure and significant economic ***,more than eight million people in Brazil live in disaster-prone *** objective of this article is to present a chronological review of the principal policies and programmes at the national,state,and municipal levels,with an emphasis on their key actions aimed at mitigating the impact of disasters related to natural hazards,particularly *** analysis was based on official records of public policies from the national,state,and municipal *** results show that several initiatives were initially developed at the local and regional ***,it was not until the late 1980s that a comprehensive organisation of civil protection at the national level emerged as a response *** is possible to highlight three phases(understanding,coexistence,and prevention)of institutional action focused on risk management in the face of *** the growing knowledge of risk scenarios,disasters continue to occur in Brazil on an annual basis,revealing several obstacles to reducing their impact,particularly given the social and economic disparities between Brazilian regions and the applicability of public policies that must overcome the limitations of each municipality.

关键词： Disasters Risk Mitigation Prevention Legislation Civil Defense Natural Hazards

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Rifaximin on epigenetics and autophagy in animal model of hepatocellular carcinoma secondary to metabolic-dysfunction associated steatotic liver disease

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World Journal of Hepatology 2024年第1期16卷 75-90页

作者： Matheus Truccolo Michalczuk Larisse Longo Melina Belén Keingeski Bruno de Souza Basso Gabriel Tayguara Silveira Guerreiro Jessica T Ferrari Joséeduardo Vargas Cláudia P Oliveira Carolina Uribe-Cruz Carlos Thadeu Schmidt Cerski eduardo Filippi-Chiela Mário ReisÁlvares-da-silva Division of Gastroenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil Graduate Program in Gastroenterology and Hepatology Universidade Federal do Rio Grande do SulPorto Alegre 90035-003Rio Grande do SulBrazil Experimental Laboratory of Hepatology and Gastroenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil Laboratory of Inflammatory and Neoplastic Cells Universidade Federal do ParanáParaná81530900Brazil Department of Gastroenterology(LIM07) Faculdade de Medicina da Universidade de São PauloSão Paulo 01246903Brazil Facultad de Ciencias de la Salud Universidad Católica de las MisionesPosadasMisiones 3300Argentina Unit of Surgical Pathology Hospital de Clinicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil Center of Biotechnology Universidade Federal do Rio Grande do SulPorto Alegre 90035-003Rio Grande do SulBrazil Department of Morphological Sciences Universidade Federal do Rio Grande do SulPorto Alegre 90.050-170Rio Grande do SulBrazil Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq) Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq)ResearcherBrasília 71.605-001Brazil

BACKGROUND Prevalence of hepatocellular carcinoma(HCC)is increasing,especially in patients with metabolic dysfunctionassociated steatotic liver disease(MASLD).AIM To investigate rifaximin(RIF)effects on epigenetic/autophagy markers in *** Adult Sprague-dawley rats were randomly assigned(n=8,each)and treated from 5-16 wk:Control[standard diet,water plus gavage with vehicle(Veh)],HCC[high-fat choline deficient diet(HFCD),diethylnitrosamine(DEN)in drinking water and Veh gavage],and RIF[HFCD,DEN and RIF(50 mg/kg/d)gavage].Gene expression of epigenetic/autophagy markers and circulating miRNAs were *** All HCC and RIF animals developed metabolic-dysfunction associated steatohepatitis fibrosis,and cirrhosis,but three RIF-group did not develop *** animals who developed HCC with those who did not,miR-122,miR-34a,tubulin alpha-1c(Tuba-1c),metalloproteinases-2(Mmp2),and metalloproteinases-9(Mmp9)were significantly higher in the *** opposite occurred with Becn1,coactivator associated arginine methyltransferase-1(Carm1),enhancer of zeste homolog-2(Ezh2),autophagy-related factor LC3A/B(Map1 Lc3b),and p62/sequestosome-1(p62/SQSTM1)-*** with controls,Map1 Lc3b,Becn1 and Ezh2 were lower in HCC and RIF-groups(P0.05).miR-122 was higher in HCC,and miR-34a in RIF compared to controls(P0.05).CONCLUSION RIF might have a possible beneficial effect on preventing/delaying liver carcinogenesis throu

关键词： Animal model Autophagy Epigenetic Hepatocellular carcinoma Metabolic dysfunction-associated steatotic liver disease Rifaximin

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Effects of Yerba Mate Consumption (Ilex paraguariensis) on Cardiac Remodeling in Rats

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Food and Nutrition Sciences 2024年第8期15卷 827-845页

作者： Carlos eduardo Brochini de Paiva Thaíssa Baptista Brochini de Paiva Isabelle Tiburcio Pecin ferreira Sandra Cristina Genaro danilo silva Martins Santos Thaoan Bruno Mariano Robson Chacon Castoldi Rafael Stuani Floriano Julia Amanda Rodrigues Fracasso Lucas Pires Guarnier Marina Politi Okoshi Francis Lopes Pacagnelli Postgraduate Program in Health Sciences Unoeste Presidente Prudente Brazil Faculty of Medicine Unoeste Presidente Prudente Brazil Department of Physiotherapy Unoeste Presidente Prudente Brazil Department of Nutrition Unoeste Presidente Prudente Brazil Postgraduate Program in Science and Movement Unesp Rio Claro Brazil Postgraduate Program in Health Promotion University of Northern Paran (UNOPAR) Londrina Brazil School of Dentistry So Paulo State University (UNESP) Araatuba Brazil Department of Genetics Ribeiro Preto Medical School University of So Paulo USP Ribeiro Preto Brazil Internal Medicine Department Botucatu Medical School So Paulo State University (UNESP) Botucatu Brazil

This study investigated the effects of yerba mate consumption, a South American beverage, on cardiac remodeling in rats. For this purpose, 24 male Wistar rats were divided into Control Group (CG) which received filtered water and a standard diet, and Yerba Mate Group (YM), 6 g of Ilex paraguariensis in 100 ml water and the same diet, for 30 days. The YM group showed a reduction in final body weight and food consumption without altering weight gain. Regarding cardiac remodeling, the YM group exhibited a decrease in the right ventricle weight/final body weight ratio, suggesting cardiac atrophy, without affecting the atria and left ventricle. There was no change in cardiomyocyte area or nuclear fractal dimension in both groups. However, animals that consumed yerba mate showed increased collagen deposition and a smaller fractal dimension in the left ventricle. The consumption of yerba mate at room temperature for 30 days induced changes in cardiac remodeling, as evidenced by increased collagen deposition and alterations in fractal dimension in the left ventricle.

关键词： Tereré Ilex paraguariensis Yerba Mate Cardiac Remodeling Fractal Dimension Hypertrophy

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Iron-Deficiency Anemia Management in Gynecological Surgery: A Review of Current Evidence and Best Practices

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Open Journal of Obstetrics and Gynecology 2024年第8期14卷 1223-1241页

作者： Aline Evangelista Santiago Artur Lima Sendin Víctor Nilo Nogueira Rogério Adão Braga Admilson Lemos Costa Filho eduardo Batista Cândido Agnaldo Lopes silva Filho Department of Gynecology and Obstetrics Faculty of Medicine Santo Amaro University (UNISA) So Paulo Brazil Department of Gynecology and Obstetrics Federal University of Minas Gerais (UFMG) Belo Horizonte Brazil Department of Gynecology and Obstetrics Faculty of Medicine So Paulo State University (UNESP) So Paulo Brazil

Purpose: Due to the high prevalence of iron deficiency anemia in women undergoing gynecological surgeries and its association with worse postoperative results, it is necessary to identify and treat anemia preoperatively. However, although anemia and iron deficiency are significant global health problems, there are still disparities in the recognition and implementation of “Patient Blood Management” (PBM) as a comprehensive approach to mitigating the risks associated with these diseases. The purpose of the study is to review best practices for the treatment of anemia based on the Enhanced Recovery After Surgery (ERAS) protocol and PBM recommendations. Methods: This study reviewed the literature on preoperative iron deficiency anemia in patients undergoing gynecological surgery. We identified references through searches in PubMed using relevant search terms. Results: Among the various strategies used in PBM, perhaps the most important is the early detection and management of anemia. In gynecological surgery, there are several approaches to reducing perioperative blood loss, highlighting the use of gonadotropin-releasing hormone (GnRH) agonists (aGnRh) and antifibrinolytics. Oral and intravenous iron supplementation can be performed in addition to blood transfusion to treat anemia. Conclusion: Addressing preoperative and postoperative anemia through systematic correction, following the guidelines of the ERAS protocol and PBM guidelines, is essential to improving perioperative outcomes in women undergoing gynecological surgery.

关键词： Anemia Gynecological Surgery Iron Supplementation Iron Deficiency

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Impacted Lower Third Molar Fused with a Supernumerary Tooth—Diagnosis and Treatment Planning Using Cone-Beam Computed Tomography

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International Journal of Oral Science 2009年第4期1卷 224-228页

作者： Osny ferreira-Junior Luciana Dorigatti de .＆.Aila Marcelo Bonifacio da silva Sampieri eduardo Dias- Ribeiro Wei-liang Chen Song Fan Department of Stomatology Dental School of Bauru University of Sao Paulo Bauru Sao Paulo Brazil Department of Stomatology the Second Affiliated Hospital Sun Yat-Sen University Guangzhou China

This paper reported a case of fusion between an impacted third molar and a supernumerary tooth, in which a surgical intervention was carried out, with the objective of removing the dental elements. The panoramic radiography was complemented by the Donovan＇s radiographic technique; but because of the proximity of the dental element to the mandibular ramus, it was not possible to have a final fusion diagnosis. Hence, the Cone-Beam Computed Tomography--which provides precise three- dimensional information--was used to determinate the fusion diagnosis and also to help in the surgical planning. In this case report we observed that the periapical, occlusal and panoramic were not able to show details which could only be examined through the cone-beam computed tomo- graphy.

关键词： third molar supernumerary tooth oral surgery,cone-beam computed tomography

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Ecological implications of twentieth century reforestation programs for the urban forests of São Paulo, Brazil: a study based on litterfall and nutrient cycling

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Ecological Processes 2021年第1期10卷 367-379页

作者： Maurício Lamano ferreira Marcelo ferreira Barbosa eduardo Pereira Cabral Gomes Ana Paula Branco do Nascimento Edgar Fernando de Luca Karina Gonçalves da silva Ulisses Bezerra França Plínio Barbosa de Camargo Raffaele Lafortezza Master’s Program in Health Promotion Adventist University of São PauloSão PauloSPBrazil. Master’s Program in Geoenvironmental Analysis University of GuarulhosGuarulhosSPBrazil. Department of Health Faculty of Biological ScienceUniversity Nove de Julho(UNINOVE)São PauloSPBrazil. Institute of Botany(IBT/SP) São PauloSPBrazil. Department of Civil Engineering São Judas Tadeu UniversitySão PauloSPBrazil. Institute of Forestry(IF/SP) São PauloSPBrazil. Centro de Energia Nuclear na Agricultura(CENA/USP) University of São PauloPiracicabaSPBrazil. Prefeitura da cidade de São Paulo(Secretaria do Verde e Meio Ambiente) São PauloSPBrazil Department of Agricultural and Environmental Sciences University of Bari Aldo MoroBariItaly. Department of Geography The University of Hong KongCentennial CampusPokfulam RoadHong KongHong Kong.

The focus of this study was to investigate the wide use of Eucalyptus spp.,an exotic plant with high allelopathic ability,in the reforestation programs of urban parks in São Paulo City,Brazil,over the last *** understand the implications of using Eucalyptus *** the city’s parks,this study aimed to compare nutrient cycling and litter decomposition between a mixed composition of litter(i.e.,native and exotic species)and the litter of a single species(i.e.,Eucalyptus).To accomplish this,newly deciduous leaves were collected from two native and two exotic species that are commonly used in the afforestation of São Paulo as well as from Eucalyptus *** mixed composition of litter yielded a higher dry mass loss and return of macro-and micronutrients to the forest *** decomposition constant(k)values were 0.00322 and 0.00207 g g^(−1) day^(−1) for the mixed composition and Eucalyptus spp.,*** time required for decomposition of 50 and 95%of deciduous material was 215 and 931 days,respectively,and for the mixed litterfall 334 and 1449 days,respectively,for Eucalyptus ***,the mixed litter exhibited greater dry mass loss and nutrient cycling in an urban forest of São Paulo City,since dry mass losses as well as speed and amount of nutrients returned to the forest floor were relatively higher compared to Eucalyptus *** cycling via Eucalyptus *** was less efficient than mixed composition of litter,demonstrating that reforestation programs carried out in the twentieth century using only one species may have had little *** results of this work emphasize the fact that in urban reforestation programs the City of São Paulo must consider the environmental and biogeographic characteristics of the species employed and use high levels of biodiversity,since the city lies in a megadiverse biome.

关键词： Tropical forest Exotic species Nutrient dynamics Ecosystem functioning

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Techno-functionality of fisetin-enriched yoghurt fermented with Lactobacillus acidophilus bio-capsules produced via osmoporation

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Systems Microbiology and Biomanufacturing 2022年第4期2卷 743-749页

作者： eduardo Wagner Vasconcelos de Andrade Sebastien Dupont Laurent Beney Edilene Souza da silva Roberta Targino Hoskin Márcia Regina da silva Pedrini Bioprocess Laboratory Chemical Engineering DepartmentUniversidade Federal do Rio Grande do NorteLagoa NovaNatalRN 59078-900Brazil Laboratory of Bioactive Compounds Chemical Engineering DepartmentUniversidade Federal do Rio Grande do NorteLagoa NovaNatalRN 59078-900Brazil UMR Procédés Alimentaires et Microbiologiques(PAM UMR A 02.102)Univ.Bourgogne Franche-ComtéAgroSup Dijon21000 DijonFrance

Osmoporation is a novel encapsulation approach for bioactive compounds based on the osmoresistance mechanisms of microbial *** the best of our knowledge,this is the first study investigating the production of fisetin-enriched yoghurt using Lactobacillus acidophilus-based bio-capsules via osmoporation as the starter *** showed that the milk acidification with fisetin-loaded *** progressed at a slower pace due to complex mechanisms induced by osmopo-ration and internalized *** fermentation using fisetin bio-capsules reached a maximum acidification rate of 0.18 pH units/h after 23 h and pH 4.6 was achieved after 32 ***,the antioxidant activity of yoghurts produced with fisetin bio-capsules did not change during cold storage,while the antioxidant activity of yoghurt produced with non-encapsulated fisetin was reduced by 2.5-fold after 28 ***,this study shows that fisetin osmoporation using *** is a versatile encapsulation bioprocess that enables the delivery of preserved phytoactives into fermented foods like *** strategy has the potential to be extended to other applications in the dairy industry using lactic acid bacteria as both the encapsulation matrix and fermentation agent.

关键词： Cell-based carriers Probiotic bacteria dairy fermented products Food biotechnology Functional foods

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Physiological Effect of Kinetin on the Photosynthetic Apparatus and Antioxidant Enzymes Activities During Production of Anthurium

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Horticultural Plant Journal 2018年第5期4卷 182-192页

作者： de MOURA Fabiana B. VIEIRA Marcos R. da S. SIMOES Adriano do N. ferreira-silva Sérgio L. de SOUZA Carlos A.V. de SOUZA eduardo S. da ROCHA Alexandre T. da silva Luzia F. JUNIOR Miguel A. Faculty of Agronomy Federal University of Pará Postgraduate Program in Plant Production Serra Talhada Academic UnitFederal Rural University of Pernambuco Department of Production Vegetable Unidade Academica de GaranhusFederal Rural University of Pernambuco

The results observed in the literature raise the hypothesis according to which cytokinin plays important roles in photosynthetic metabolisms and antioxidant enzymes. Thus, the study aimed to evaluate the effect of foliar application of the isolated cytokinin kinetin at the production cycle, seeking to analyze its effects on enzyme activity and photosynthetic parameters. The plants treated with CK presented reduction of leaf CO_2 assimilation rate(Pn) and stomatal conductance(Gs), while that transpiration rate(Tr) was unaffected. The internal CO_2 concentrations decreased with the increase in cytokinin levels, but were maintained under CK 50 mg·L^(-1). The plants treated with CK 75 mg·L^(-1) was verified higher carboxylation efficiency(Pn/Ci), which was associated to values of CO_2 assimilation and transpiration unaltered. Apparent electron transport rate showed variations in the concentration of 25 mg·L^(-1). Considering the study of enzyme activity, on the other hand, it cannot be stated that kinetin has an effective action in delaying oxidative damage. It presents mixed results, since an efficiency in the application of cytokinin was not observed, presenting induction levels of ascorbate peroxidase activity. Thus, further research is needed to determine more precisely the effects of kinetin on gas exchange and antioxidant enzymes in anthurium plants.

关键词： anthurium kinetin photosynthesis senescence plant hormone oxidative stress

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