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关于环境的建筑：华黎与迹·建筑事务所

城市环境设计 2019年第6期122卷 35-48页

作者： eduard K?gel 傅骁 Aedes Berlin

华黎于1989到1997年间在北京的清华大学学习,之后去了美国的耶鲁大学进修。在美国与中国工作一段时间之后,他在2009年于北京创立了迹·建筑事务所。本文将对他之后十年间的建筑实践进行概述。华黎的许多作品都位处乡村的开放景观中,并... 详细信息

华黎于1989到1997年间在北京的清华大学学习,之后去了美国的耶鲁大学进修。在美国与中国工作一段时间之后,他在2009年于北京创立了迹·建筑事务所。本文将对他之后十年间的建筑实践进行概述。华黎的许多作品都位处乡村的开放景观中,并具有特定的用途,例如教育、娱乐和工作等,都是改善乡村生活状况的重要话题。近年来,中国的乡村地区正面临的挑战引发了业界的广泛讨论,同时也在国际社会产生了一些影响和回应。1贫困问题,以及农村年轻

关键词：建筑事务所

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无机颗粒与金属在表面上电共沉积工艺

表面技术 1985年第2期 50-56页

作者： eduard Zuurdeeg 胡信国姚杰哈尔滨工业大学哈尔滨工业大学

本工艺提供了金属和固体无机颗粒在阴极零件上电共沉积方法。颗粒平均尺寸小于300μm,在镀液中的浓度为10～150克/升。无机颗粒悬浮在含氟碳表面活性剂的槽液中。表面活性剂含量至少使槽液中颗粒的重量比与表面活性剂对颗粒的重量比相... 详细信息

本工艺提供了金属和固体无机颗粒在阴极零件上电共沉积方法。颗粒平均尺寸小于300μm,在镀液中的浓度为10～150克/升。无机颗粒悬浮在含氟碳表面活性剂的槽液中。表面活性剂含量至少使槽液中颗粒的重量比与表面活性剂对颗粒的重量比相同。颗粒在0.005NKNO3溶液中的ζ电位至少为+40mv,适合的阳离子氟碳化合物表面活性剂组成应具有以下分子结构:

关键词：无机颗粒表面活性剂水泥外加剂电共沉积金属金属材料

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无机颗粒与金属在表面上电共沉积工艺

包装工程 1985年第2期 50-56页

作者： eduard Zuurdeeg 胡信国姚杰哈尔滨工业大学哈尔滨工业大学

本工艺提供了金属和固体无机颗粒在阴极零件上电共沉积方法。颗粒平均尺寸小于300μm,在镀液中的浓度为10～150克/升。无机颗粒悬浮在含氟碳表面活性剂的槽液中。表面活性剂含量至少使槽液中颗粒的重量比与表面活性剂对颗粒的重量比相同。颗粒在0.005NKNO3溶液申的ζ电位至少为+40mv,适合的阳离子氟碳化合物表面活性剂组成应具有以下分子结构: 2[C8F17SO2——（CH2）8—N （CH3）3]SO42-

关键词：无机颗粒表面活性剂水泥外加剂电共沉积金属金属材料

Enhacement of the Viability of <i>Lactobacillus</i><i>plantarum</i>during the Preservation and Storage Process Based on the Response Surface Methodology

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Food and Nutrition Sciences 2014年第18期5卷 1746-1755页

作者： Girme Gisela Arosemena Esteban Leonardo Perez Lucia Vera Rodrigo Grau eduard Calvo M. Angeles Grupo de Microbiología Aplicada y Medio-ambiental Facultad de Veterinaria Universidad Autónoma de Barcelona Bellaterra (Barcelona) Spain

Objective: The Response Surface Methodology (RSM) is a commonly used system to optimize cell viability of probiotic strains when they are subjected to different preservation and storage processes. Methods and Results: To determine the optimal levels of incorporation of several cry oprotectants (skim milk, sucrose and trehalose) in the freeze-drying process of Lactobacillus plantarum, a range of experiments based on a Rotational Central Composite design (CCD) were conducted. The results were adjusted to a quadratic model, resulting in the presence of interaction between the different variables. Solving a regression equation, we obtained the optimum concentrations of cryoprotective agents: 24.06% milk powder, 6.22% sucrose, 5.63% trehalose. To visualize the interactions between the three variables involved in the study, Design Expert? software was used. Conclusions: The analysis reveals that while trehalose has a direct effect on the viability of L. plantarum, skim milk and sucrose exert quadratic effects. There are also interactions between cryoprotectants, which emphasize the synergies produced between milk and sucrose and between sucrose and trehalose, which allows maintaining the viability of L. plantarum. Significance and Impact of the Study: The addition of new oligosaccharides as trehalose in premixtures for functional feed can maintain the viability of L. plantarum during longer periods of time, ensuring the proper administration of probiotics to their destinations.

关键词： Cryoprotectants Freeze-Drying Process Probiotics Response Surface Methodology Central Composite Design

Big data technology in infectious diseases modeling,simulation,and prediction after the COVID-19 outbreak

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智慧医学(英文) 2023年第2期3卷 85-96页

作者： Honghao Shi Jingyuan Wang Jiawei Cheng Xiaopeng Qi Hanran Ji Claudio J Struchiner Daniel AM Villela eduard V Karamov Ali S Turgiev School of Computer Science and Engineering Beihang UniversityBeijing 100191China Center for Global Public Health Chinese Center for Disease Control and PreventionBeijing 102211China Fundação Getúlio Vargas Rio de JaneiroBrazil Instituto de Medicina Social Hesio Cordeiro Universidade do Estado do Rio de JaneiroRio de JaneiroBrazil Programa de Computação Científica Fundação Oswaldo CruzRio de JaneiroBrazil Gamaleya National Research Center for Epidemiology and Microbiology of the Russian Ministry of Health Russia National Medical Research Center of Phthisiopulmonology and Infectious Diseases of the Russian Ministry of Health Russia

After the outbreak of COVID-19,the interaction of infectious disease systems and social systems has challenged traditional infectious disease modeling *** from the research purpose and data,researchers im-proved the structure and data of the compartment model or used agents and artificial intelligence based models to solve epidemiological *** terms of modeling methods,the researchers use compartment subdivi-sion,dynamic parameters,agent-based model methods,and artificial intelligence related *** terms of factors studied,the researchers studied 6 categories:human mobility,nonpharmaceutical interventions(NPIs),ages,medical resources,human response,and *** researchers completed the study of factors through modeling methods to quantitatively analyze the impact of social systems and put forward their suggestions for the future transmission status of infectious diseases and prevention and control *** review started with a research structure of research purpose,factor,data,model,and *** on the post-COVID-19 infectious disease prediction simulation research,this study summarized various improvement methods and analyzes matching improvements for various specific research purposes.

关键词： Infectious disease model Data embedding Social system Dynamic Modeling the social systems

Traditional Chinese Medicine-Based Subtyping of Early-Stage Type 2 Diabetes Using Plasma Metabolomics Combined with Ultra-Weak Photon Emission

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Engineering 2019年第5期5卷 916-923页

作者： Min He Mengmeng Sun Slavik Koval Roeland Van Wijk Thomas Hankemeier Jan Van der Greef eduard P.A.Van Wijk Mei Wang Leiden University–European Center for Chinese Medicine and Natural Compounds Institute of BiologyLeiden UniversityLeiden 2333 BEthe Netherlands Analytical BioSciences Leiden Academic Center for Drug Research(LACDR)Leiden UniversityLeiden 2333 CCthe Netherlands Changchun University of Chinese Medicine Changchun 130117China Sino-Dutch Center for Preventive and Personalized Medicine Tiel 4002 AGthe Netherlands Meluna Research Geldermalsen 4191 LCthe Netherlands SU Biomedicine Leiden 2300 AMthe Netherlands Shenzhen Huakai Traditional Chinese Medicine and Natural Medicine Research Center Shenzhen 518114China

The prevalence of type 2 diabetes mellitus(T2DM)is increasing rapidly *** of the limited success of generic interventions,the focus of the disease study has shifted toward personalized strategies,particularly in the early stages of the *** Chinese medicine(TCM)is based on a systems view combined with personalized strategies and has improved our knowledge of personalized *** a systems biology perspective,the understanding of personalized diagnostics can be improved to yield a biochemical basis for such strategies;for example,metabolomics can be used in combination with other system-based diagnostic methods such as ultra-weak photon emission(UPE).In this study,we investigated the feasibility of using plasma metabolomics obtained from 44 pre-T2DM subjects to stratify the following TCM-based subtypes:Qi-Yin deficiency,Qi-Yin deficiency with dampness,and Qi-Yin deficiency with *** studied the relationship between plasma metabolomics and UPE with respect to TCM-based subtyping in order to obtain biochemical information for further interpreting disease *** component analysis of plasma metabolites revealed differences among the TCM-based pre-T2DM *** high levels of lipids(e.g.,cholesterol esters and triglycerides)were important discriminators of two of the three subtypes and may be associated with a higher risk of cardiovascular *** metabolomics data indicate that the lipid profile is an essential component captured by UPE with respect to stratifying subtypes of *** results suggest that metabolic differences exist among different TCM-based subtypes of pre-T2DM,and profiling plasma metabolites can be used to discriminate among these *** metabolomics thus provides biochemical insights into system-based UPE measurements.

关键词： Type 2 diabetes mellitus Plasma metabolites Disease subtypes Ultra-weak photon emission Correlation networks

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Cortical thickness abnormalities in patients with first episode psychosis:a meta-analysis of psychoradiologic studies and replication in an independent sample

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Psychoradiology 2021年第4期1卷 185-198页

作者： Keren Wen Youjin Zhao Qiyong Gong Ziyu Zhu Qian Li Nanfang Pan Shiqin Fu Joaquim Radua eduard Vieta Poornima Kumar Graham J.Kemp Bharat B.Biswal Huaxi MR Research Center(HMRRC) Department of RadiologyWest China Hospital of Sichuan UniversityChengdu 610041SichuanChina Research Unit of Psychoradiology Chinese Academy of Medical SciencesChengdu 610041SichuanChina Functional and Molecular Imaging Key Laboratory of Sichuan Province Chengdu 610041SichuanChina Institut d’Investigacions Biom`ediques August Pi i Sunyer(IDIBAPS) Mental Health Research Networking Center(CIBERSAM)Barcelona 08036CataloniaSpain Centre for Psychiatric Research and Education Department of Clinical NeuroscienceKarolinska InstitutetSolna 171-77StockholmSweden Department of Psychosis Studies Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon WC2R 2LSUK Barcelona Bipolar Disorders and Depressive Unit Hospital ClinicInstitute of NeurosciencesUniversity of BarcelonaBarcelona 08036CataloniaSpain Center for Depression Anxiety and Stress ResearchMcLean HospitalBelmont 02478MAUSA Department of Psychiatry Harvard Medical SchoolBoston 02115MAUSA Liverpool Magnetic Resonance Imaging Centre(LiMRIC)and Institute of Life Course and Medical Sciences University of LiverpoolLiverpool L693GEUK Department of Biomedical Engineering New Jersey Institute of TechnologyNewark 07102NJUSA The Clinical Hospital of Chengdu Brain Science Institute MOE Key Laboratory for NeuroinformationUniversity of Electronic Science and Technology of ChinaChengdu 610054SichuanChina

Background:Abnormalities of cortical thickness(CTh)in patients with their first episode psychosis(FEP)have been frequently reported,but findings are ***:To define the most consistent CTh changes in patients with FEP by meta-analysis of publishedwholebrain ***:The meta-analysis used seed-based dmapping(SDM)software to obtain the most prominent regional CTh changes in FEP,and meta-regression analyses to explore the effects of demographics and clinical *** meta-analysis results were verified in an independent sample of 142 FEP patients and 142 age-and sex-matched healthy controls(HCs),using both a vertex-wise and a region of interest analysis,with multiple comparisons ***:The meta-analysis identified lower CTh in the rightmiddle temporal cortex(MTC)extending to superior temporal cortex(STC),insula,and anterior cingulate cortex(ACC)in FEP compared with *** significant correlations were identified between CTh alterations and demographic or clinical *** results were replicated in the independent dataset ***:This study identifies a robust pattern of cortical abnormalities in FEP and extends understanding of gray matter abnormalities and pathological mechanisms in FEP.

关键词： psychoradiology first episode psychosis early psychosis cortical thickness meta-analysis seed-based d mapping

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预训练语言模型及其应用（英文）

Engineering 2023年第6期 51-65页

作者：王海峰李纪为 Hua Wu eduard Hovy Yu Sun Baidu Inc. College of Computer Science and Technology Zhejiang University Language Technologies Institute Carnegie Mellon University

预训练语言模型（pre-trained languages model, PTLM）在自然语言处理（natural language processing,NLP）领域取得了令人瞩目的成功，并由此引发了下游任务从监督学习到预训练-微调范式的转变。在此之后，一系列预训练模型的创新研...

预训练语言模型（pre-trained languages model, PTLM）在自然语言处理（natural language processing,NLP）领域取得了令人瞩目的成功，并由此引发了下游任务从监督学习到预训练-微调范式的转变。在此之后，一系列预训练模型的创新研究涌现出来。本文系统性、全面的回顾了自然语言处理的代表性工作和最新进展，并按照类别系统性的介绍了自然语言处理领域的预训练模型。首先我们简要介绍了预训练模型，以及不同的模型特点和框架。之后，我们介绍并分析了预训练模型的影响和挑战以及下游任务中的应用。最后，我们简要总结并阐述了预训练模型未来的研究方向。

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一种新型超音速喷枪性能研究

有色金属（冶炼部分） 2008年第S1期 120-126页

作者： Andreas Wank Alexander Schwenk Bernhard Wielage Thomas Grund Gerd Paczkowski eduard Friesen 德国GTV公司北京100000 Lehrstuhl für Verbundwerkstoffe Technische Universitt ChemnitzChemnitzDeutschland

对一种新型基于流体动力学基础上研制的超音速喷枪的性能进行研究。使用常规超音速喷枪及新型超音速喷枪进行对比喷涂实验,结果显示新型喷枪有着明显的优势。新型超音速燃烧室及枪管使火焰与颗粒间的动能和热能交换更加均匀。涂层性能... 详细信息

对一种新型基于流体动力学基础上研制的超音速喷枪的性能进行研究。使用常规超音速喷枪及新型超音速喷枪进行对比喷涂实验,结果显示新型喷枪有着明显的优势。新型超音速燃烧室及枪管使火焰与颗粒间的动能和热能交换更加均匀。涂层性能对比试验显示使用改进型喷枪所获得的涂层显微硬度及致密性有一定的提高,而涂层冶金反应却明显地减少了。在对涂层按ASTM G65标准进行检测中发现,涂层的耐磨性能也得到了明显的提升。

关键词：流体动力学超音速喷枪燃烧室超音速枪管

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