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Extrahepatic cholestasis associated with paracoccidioidomycosis:Challenges in the differential diagnosis of biliopancreatic neoplasia

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2531-2540页

作者： Jose Sebastiao dos Santos Vitor de Moura Arrais William Jose Rosseto Ferreira Ricardo Ribeiro Correa Filho Mariangela Ottoboni Brunaldi Rafael Kemp Ajith Kumar Sankanrakutty Jorge Elias Junior fernando Bellissimo-rodrigues Roberto Martinez edson Zangiacomi Martinez Jose Celso Ardengh Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP) Departamento de Cirurgia e AnatomiaRibeirao Preto 14049-900Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de PatologiaRibeirao Preto 14048900Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Imagens MédicasHematologia e Oncologia ClínicaRibeirao Preto 14048900Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Medicina SocialRibeirao Preto 14015-010Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Clínica MédicaRibeirao Preto 14015-010Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Cirurgia e AnatomiaRibeirao Preto 14049-900Sao PauloBrazil and Hospital MoriahServico de Endoscopia DigestivaSao Paulo 04084-002Sao PauloBrazil

BACKGROUND Paracoccidioidomycosis(PCM)may involve the hepatic pedicle and peripan creatic lymph nodes,cause damage to the bile duct and manifest,exceptionally,in combination with extrahepatic cholestasis(EHC),making investigation and treatment *** To investigate the management of patients with visceral PCM admitted with *** All patients diagnosed with PCM treated in a public,tertiary teaching hospital between 1982 and 2020 were retrospectively *** also identified with EHC were allocated to two groups according to the treatment approach for the purpose of comparing clinical,laboratory,and imaging findings,resources used for etiological diagnosis,treatment results,and *** analyses were performed using the linear mixed-effects model(random and fixed effects),which was adjusted using the PROC MIXED procedure of the SAS®9.0 software,and Fisher’s exact *** Of 1645 patients diagnosed with PCM,40(2.4%)had *** these,20(50.0%)lived in the rural area and 29(72.5%)were men,with a mean age of 27.1 years(3-65 years).Jaundice as first symptom and weight loss of at least 10 kg were observed in 16 patients(40.0%),and a mass in the head of the pancreas was observed in 8(20.0%).The etiological diagnosis was made by tissue collection during surgery in 4 cases(10.0%)and by endoscopic methods in 3 cases(7.5%).Twenty-seven patients(67.5%)received drug treatment alone(Group 1),whereas 13(32.5%)underwent endoscopic and/or surgical procedures in combination with drug treatment(Group 2).EHC was significantly reduced in both groups(40.7% in Group 1,with a mean time of 3 months;and 38.4% in Group 2,with a mean time of 7.5 months),with no statistically significant difference between *** recurrence rates,associated mainly with treatment nonadherence,were similar in both groups:37% in Group 1 and 15.4% in Group *** mortality rate was 18.5% in Group 1 and 23% in Group 2,with survival estimates of 71.3% and 72.5%,respectively,with

关键词： Cholestasis Jaundice Obstructive Blastomycosis Paracoccidioides Diagnosis Treatment

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Determination of the Adhesive Content of Medium Density Particleboards Produced with Bio-based Polymer

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Journal of Building Material Science 2019年第2期1卷 20-24页

作者： Vinícius Borges de Moura Aquino edson fernando castanheira rodrigues Isabela Matias Pietrobon AndréLuis Christoforo Francisco Antonio Rocco Lahr Tulio Hallak Panzera Department of Civil Engineering Federal University of the Southern and Southeastern ParáBrazil Department of Civil Engineering Federal University of São Carlos-UFSCarBrazil Structural Engineering Department São Carlos School of EngineeringUniversity of São Paulo-USPBrazil Centre for Innovation and Technology in Composite Materials-CITeC Department of Mechanical and Production EngineeringFederal University of São João dal-Rei-UFSJBrazil

This work contributes to the use of alternative adhesives in the wood-based industry,where pine wood is commonly *** investigation identifies the influence and the optimal content(8,12 and 15wt%)of a bio-based polyurethane adhesive in the production of medium density particleboards(MDP).A compaction pressure of 4 MPa at 100oC for 10 minutes is considered in the manufacture of panels based on pine wood residues and bio-based *** bulk density,flexural modulus(MOE)and strength(MOR)properties under static three-point bending are obtained according to the Brazilian standard NBR *** results are compared with NBR 14810 and other standards to verify its performance based on the minimum *** density is not significantly affected by the investigated adhesive *** and MOR reach average values equivalent to 12wt%and 15wt%of the adhesive,and both meet the minimum requirements established in international normative *** adhesive level range responsible for maximizingρ,MOE and MOR is between 12.42wt%and 15.79wt%.

关键词： Particleboard Pinus wood Bio-based adhesive Tukey test Regression model

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Characterization and electrochemical performance of CeO2 and Eu-doped CeO2 films as a manganese redox flow battery component

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Journal of Rare Earths 2018年第10期36卷 1074-1083页

作者： Monica A.rodrigues Ariadne C.Catto Elson Longo edson Nossol Renata C.Lima Institute of Chemistry.Federal University of Uberlandia 38400-902UberlandiaMGBrazil Institute of Chemistry Sao Paulo State UniversityP.O.Box 35514801-907Araraquara.SPBrazil LIEC Department of ChemistryFederal University of Sao Carlos13565-905Sao CarlosSPBrazil

Hexagonal CeO2 and Eu-doped CeO2 nanoparticles were obtained using a facile microwave-hydro thermal method under mild conditions and their application towards manganese redox flow battery component were studied. The structural properties were studied by X-ray diffraction and indicate that samples present a fluorite structure. Raman spectroscopy shows Eu3＋ ions substitute Ce4＋ and generate oxygen vacancies. Electrochemical properties of pure and Eu-doped CeO2 films deposited at graphite substrates investigated by cyclic voltammetry and galvanostatic charge-discharge indicate that dopant concentration affects the electrochemical properties of CeO2. The increase in the reversibility redox of electrochemical systems observed is attributed to coexistence of Ce4＋/Ce3＋ redox couple confirmed by ***-discharge tests display coulombic and voltage efficiency values of above 80% and 90%, respectively. The obtained specific capacity for Ce（0.99）Eu（0.01）O2（372.49 mAh/g） and pure oxide（334.84 mAh/g）indicates that both samples are promising for application in Mn-batteries.

关键词： Cerium oxide Europium Nanoparticles Electrochemical properties Batteries Rare earths

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Effects of perinatal protein deprivation and recovery on esophageal myenteric plexus

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World Journal of Gastroenterology 2010年第5期16卷 563-570页

作者： Flavio M Greggio Ricardo BV Fontes Laura B Maifrino Patricia Castelucci Romeu rodrigues de Souza edson A Liberti Autonomic Nervous System Laboratory (VQM) Department of Anatomy Instituto de Ciencias Biomedicas da Universidade de Sao Paulo 2415 Av Prof Lineu Prestes 05508-900 So Paulo Brazil

AIM:To evaluate effects of preand postnatal protein deprivation and postnatal recovery on the myenteric plexus of the rat esophagus. METHODS: Three groups of young Wistar rats (aged 42 d) were studied: normalfed (N42), proteindeprived (D42), and proteinrecovered (R42). The myenteric neurons of their esophagi were evaluated by histochemical reactions for nicotinamide adenine dinucleotide (NADH), nitrergic neurons (NADPH)diaphorase and acetylcholinesterase (AChE), immunohistochemical reaction for vasoactive intestinal polypeptide (VIP), and ultrastructural analysis by transmission electron ***: The cytoplasms of large and medium neurons from the N42 and R42 groups were intensely reactive for NADH. Only a few large neurons from the D42 group exhibited this aspect. NADPH detected in the D42 group exhibited low reactivity. The AChE reactivity was diffuse in neurons from the D42 and R42 groups. The density of large and small varicosities detected by immunohistochemical staining of VIP was low in ganglia from the D42 group. In many neurons from the D42 group, the double membrane of the nuclear envelope and the perinuclear cisterna were not detectable. NADH and NADPH histochemistry revealed no group differences in the prof ile of nerve cell perikarya (ranging from 200 to 400 μm2).CONCLUSION: Protein deprivation causes a delay in neuronal maturation but postnatal recovery can almost completely restore the normal morphology of myenteric neurons.

关键词： Esophagus Enteric nervous system Myenteric plexus Proteins Light microscopy Transmission electron microscopy

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Genetic Improvement of Barley (<i>Hordeum vulgare</i>, L.) in Brazil: Yield Increase and Associated Traits

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Agricultural Sciences 2020年第4期11卷 425-438页

作者： Osmar rodrigues Euclydes Minella edson Roberto Costenaro Brazilian Agricultural Research Corporation Embrapa Wheat Passo Fundo RS Brazil

Barley breeding program in Brazil has focused on characteristics associated with malting for beer purposes as the main economic application for this crop. The breeding process focused on selection for grain yield, disease resistance and malting quality. The objective of this work was to quantify the genetic gain in barley grain yield from 1968 and 2008 in Brazil and to identify the physiological characteristics associated with the increase of grain yield. Field experiments with five 2-row barley cultivars were tested from 2011 to 2013 in the absence of biotic and abiotic stresses and with mechanical restriction to lodging. The ANOVA showed no genetic gain until 1980 with average grain yield of 4.632 kg/ha. After 1980, there was a productivity increase of 59.9 kg/ha/year. No correlation was observed between total maturity biomass and the year of release of the cultivars, while harvest index and plant height, were significantly improved. The main component associated with grain yield was the number of grains/m2, due to the higher number of spikes/m2 associated to a greater contribution of the tillers in the modern cultivars.

关键词： Barley Grain Yield Developmental Phases Genetic Gain Yield Components

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COVID-19 Downgraded Already Impaired Mental Health of Medical Undergraduates during the Pandemic Years

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Journal of Biosciences and Medicines 2023年第5期11卷 166-180页

作者： Rodrigo Corrêa Falcão rodrigues Alves Rodolffo da Silva Fossa Vinicius de Calasans Timaco José Mariano Soares de Moraes Emilio Magalhães Martins Will Rinaldo Henrique Aguilar da Silva Luiz Antonio Vane Joaquim edson Vieira Matheus Fachini Vane Faculdade de Ciências Médicas de Sã o José dos Campos S&atildeo José dos Campos Brazil Department of Anesthesiology Juiz de Fora Federal University Juiz de Fora Brazil Department of Anesthesiology Clinics Hospital University of S&atildeo Paulo Medical School S&atildeo Paulo Brazil Discipline of Anesthesiology Department of Surgery University of S&atildeo Paulo Medical School S&atildeo José dos Campos Brazil

Background: Measures to contain the COVID-19 transmission reached teaching routines of universities worldwide with possible mental health consequences for anxiety. This study assessed prevalence and risk factors for stress, depression, and anxiety (SDA) in medical students during quarantine by COVID-19. Methods: A cross-sectional observational study of medical students by means of the DASS-21 questionnaire. Risk factors for SDA were assessed based on epidemiologic questions related to COVID-19. Receiver Operating Characteristics (ROC) curves were calculated for each predictor, as well as sensitivity and specificity. Results: This survey reached 1009 responses. A prevalence of 77.5% for some SDA disorder was found, 63% being severe. Previous diagnosis of psychiatric disorder was a factor of risk for anxiety (OR 2.78 CI95% 1.44 - 14.25, p = 0.044), as well as for depression (OR 3.37 CI95% 1.98 - 6.02, p Conclusion: Psychiatric conditions as well as chronic illnesses were risk factors for high prevalence of anxiety, depression and stress during the COVID-19 pandemic among medical students.

关键词： Mental Health COVID-19 Students Medical Surveys and Questionnaires

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Influence of Vernalization and Photoperiod on the Duration of Stem Elongation and Spikelet Fertility in Wheat

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Agricultural Sciences 2014年第14期5卷 1547-1557页

作者： Osmar rodrigues Mauro César Celaro Teixeira edson Roberto Costenaro Leandro Vargas Rafael Damo Embrapa Wheat Passo Fundo Brazil University of Passo Fundo Passo Fundo Brazil

A longer stem elongation phase (from the terminal spikelet-TS to the anthesis-ANT phases) increases grain production due to an increase in spikelet fertility. However, the mechanism behind the greater number of fertile flowers that occur when the duration of stem elongation is modified by photoperiod and vernalization is not fully understood. The goal of this study was to investigate the effect of combinations of photoperiod and vernalization on the duration of stem elongation and spikelet fertility in wheat. Thus, a greenhouse experiment was performed by subjecting 13 wheat genotypes to two vernalization regimes (V0—non-vernalized plants and V40—plants with 40 vernalization days) and to two photoperiod regimes (NP—natural and NP + 6—photoperiod extended by six hours), during the stem elongation phase. The natural photoperiod increased the spikelet fertility of eight cultivars without a corresponding increased duration of the TS-ANT phase, suggesting the existence of a direct effect of photoperiod on increased spikelet fertility. Vernalization increased the duration of the TS-ANT phase, without influencing spikelet fertility. There was genetic variability in the responses to photoperiod and vernalization.

关键词： Double Ridge Terminal Spikelet Elongation

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Culture of Scenedesmus acuminatus in Corn Steep Liquor

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Journal of Agricultural Science and Technology(B) 2017年第5期7卷 346-350页

作者： Cristiane Tomas Kubo] Rafael Luan Sehn Canevest edson Antonio da Silva , Nyamien Yahaut Sebastien Tatiana rodrigues da Silva Baumgartner Center of Engineering and Exact Sciences Western Parandt State University Toledo 85903-000 Brazil

Microalgae have been evaluated as a source of lipids for biodiesel production. They can be grown on effluent and produce biomass while removing organic and mineral components from the medium. The use of agro-industrial wastes for the production of microalgae is an alternative to reduce the costs related to the composition of the culture medium, thus reducing operational costs considerably. This work was conceived as a research about the cultivation of microalgae Scenedesmus acuminatus on the substrate composed by corn steep liquor. A central composite design (CCD) was carried to study the influence of the effluent and inoculum concentration on the chemical oxygen demand (COD) of the culture. Statistical analysis indicated that the percentage of inoculum and effluent had an influence on the COD. The cultivation, together with the coagulation procedure, was efficient for the removal of organic matter, verified through the COD reduction and changing of pH value. These two parameters reached the appropriate level according to the standard required by current legislation.

关键词：文化白酒玉米电荷耦合器件类脂化合物统计分析凝结过程接种物

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Scientific development of smart farming technologies and their application in Brazil

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Information Processing in Agriculture 2018年第1期5卷 21-32页

作者： Dieisson Pivoto Paulo Dabdab Waquil edson Talamini Caroline Pauletto Spanhol Finocchio Vitor Francisco Dalla Corte Giana de Vargas Mores Universidade Federal do Rio Grande do Sul Center for Studies and Research in Agribusiness7712 Bento Gonc¸alves AvenueAgronomy DistrictPorto AlegreState of Rio Grande do SulBrazil Universidade Federal do Rio Grande do Sul Department of Economics and Foreign Affairs and Center for Studies and Research in Agribusiness7712 Bento Gonc¸alves AvenueAgronomy DistrictPorto AlegreState of Rio Grande do SulBrazil Universidade Federal do Rio Grande do Sul 7712 Bento Gonc¸alves AvenueAgronomy DistrictPorto AlegreState of Rio Grande do Sul 33086-586Brazil Meridional University–IMED Business School304 Senador Pinheiro StreetRodrigues DistrictPasso FundoState of Rio Grande do Sul 99070-220Brazil Universidade Federal do Rio Grande do Sul Universidade Comunitária da Região de Chapecò7712 Bento Gonc¸alves AvenueAgronomy DistrictPorto AlegreState of Rio Grande do Sul 33086-586Brazil

Smart farming(SF)involves the incorporation of information and communication technologies into machinery,equipment,and sensors for use in agricultural production *** technologies such as the internet of things and cloud computing are expected to advance this development,introducing more robots and artificial intelligence into ***,the aims of this paper are twofold:(i)to characterize the scientific knowledge about SF that is available in the worldwide scientific literature based on the main factors of development by country and over time and(ii)to describe current SF prospects in Brazil from the perspective of experts in this *** research involved conducting semi-structured interviews with market and researcher experts in Brazil and using a bibliometric survey by means of data mining *** between the different available systems on the market was identified as one of the main limiting factors to SF *** limiting factor is the education,ability,and skills of farmers to understand and handle SF *** limitations revealed a market opportunity for enterprises to explore and help solve these problems,and science can contribute to this ***,the United States,South Korea,Germany,and Japan contribute the largest number of scientific studies to the *** that invest more in R&D generate the most publications;this could indicate which countries will be leaders in smart *** use of both research methods in a complementary manner allowed to understand how science frame the SF and the mains barriers to adopt it in Brazil.

关键词： Agricultural innovation Big data Data in agriculture Information technology Text mining

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Analysis of the stomatognathic system after anterior cruciate ligamentplasty

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Open Journal of Stomatology 2012年第2期2卷 88-94页

作者： Bruno Ferreira Gabriel Pádua da Silva edson Donizetti Verri Marisa Semprini Selma Siéssere Emanuela Martins Nepomuceno Victor rodrigues Nepomuceno Camila Melo de Carvalho Simone Cecilio Hallak Regalo Departamento de Morfologia Estomatologia e FisiologiaFaculdade de Odontologia de Ribeirao Preto(FORP-USP)Ribeirao PretoBrazil Departamento de Fisioterapia Centro Universitário UNIFAFIBEBebedouroBrazil Departamento de Fisioterapia Centro Universitário Claretiano de BatataisBatataisBrazil Departamento de Fisioterapia Centro Universitário Luterano de PalmasPalmasBrazil

Objective: The purpose of this study was to investigate the presence of postural imbalances, which can interfere with the mandible position and affect the actions of the stomatognathic system. Materials and Methods: Forty men, aged between 23 to 29 years, were selected and divided into two groups: Group I comprised 20 healthy individuals with no clinical postural change diagnosis;Group II, 20 individuals who had ACL surgical, unilateral with patellar tendon graft, paired individual to individual (age and weight). All of them were submitted to an electromyography in different clinical conditions. In addition, a condylar biomechanical assessment was performed through videogrametry. Results: In electromyography and videogrametry, a normal standard biomechanical was observed for both groups, however, Group GII—Ligamentplasty presented an inhibition of the masticatory muscles and decreased joint kinesthetic. Conclusion: Based on the results obtained, it was concluded that after the reconstruction of the ACL, individuals presented changes in the stomatog-nathic system.

关键词： Electromyography Stomatognathic System Anterior Cruciate Ligament

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