检索结果-南通市图书馆

Provenance of Conglomerate and Sandstone from Early Permian Shoushangou Formation in Xi Ujimqin,Inner Mongolia:Implications for Understanding Paleo-Asian Ocean Subduction

在线全文

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2024年第1期98卷 10-31页

作者： ZHANG Yingli GUO Xianqing ma Shouxian MNR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesCAGSBeijing 100037China Chinese Academy of Geological Sciences Beijing 100037China

During the Late Carboniferous to Early Permian,a rift was formed by post-collisional extension after ocean closure or an island arc-related basin formed by Paleo-Asian Ocean(PAO)subduction in the Xi Ujimqin ***,the closure time of the PAO is still under ***,to identify the origin of the PAO,the geochemistry and U-Pb age of zircons were analyzed for the extra-large deep marine,polymict clastic boulders and sandstones in the Shoushangou Formation within the *** analyses revealed magmatic activity and tectonic *** conglomerates include megaclasts of granite(298.8±9.1 ma)and granodiorite porphyry(297.1±3.1 ma),which were deposited by muddy debris *** of this study demonstrated that the boulders of granitoids have the geochemistry of typical I-type granite,characterized by low Zr+Nb+Ce+Y and low Ga/Al *** granitoid boulders were formed in island arc setting,indicating the presence of arc magmatism in the area that is composed of the Late Carboniferous to Early Permian subduction-related granitoid in southern Xi *** diagrams for determining sedimentary provenance using major and trace elements indicate that Shoushangou sediments originated from continental island arc-related felsic *** zircon U-Pb age cluster of 330–280 ma was obtained,indicating input from granite,ophiolite,Xilin Gol complex,and Carboniferous sources to the *** basin was geographically developed behind the arc during the Early Permian period because the outcropped intrusive rocks in the Late Carboniferous to Early Permian form a volcanic *** comprehensive analyses of source areas suggest that Shoushangou sediments developed in a backarc basin in response to the northward subduction of the *** backarc basin and intrusive rocks,in addition to previously published Late Carboniferous to Early Permian magmatic rocks of arc unit in Xilin Gol,confirm the presence of an Early Permian trencharc-basin system in the region,r

关键词： provenance analysis backarc basin Shoushangou Formation Early Permian Central Asian Orogenic Belt

Potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第10期19卷 2144-2156页

作者： Ying ma Yue Qiao Xiang Gao Spinal Cord and Brain Injury Research Group Stark Neuroscience Research InstituteIndianapolisINUSA department of Neurological Surgery Indiana University School of MedicineIndianapolisINUSA department of Neurology Shengjing Hospital of China Medical UniversityShenyangLiaoning ProvinceChina

It has been reported both in clinic and rodent models that beyond spinal cord injury directly induced symptoms, such as paralysis, neuropathic pain, bladder/bowel dysfunction, and loss of sexual function, there are a variety of secondary complications, including memory loss, cognitive decline, depression, and Alzheimer's disease. The largescale longitudinal population-based studies indicate that post-trauma depression is highly prevalent in spinal cord injury patients. Yet, few basic studies have been conducted to address the potential molecular mechanisms. One of possible factors underlying the depression is the reduction of adult hippocampal neurogenesis which may come from less physical activity, social isolation, chronic pain, and elevated neuroinflammation after spinal cord injury. However, there is no clear consensus yet. In this review, we will first summarize the alteration of hippocampal neurogenesis post-spinal cord injury. Then, we will discuss possible mechanisms underlie this important spinal cord injury consequence. Finally, we will outline the potential therapeutic options aimed at enhancing hippocampal neurogenesis to ameliorate depression.

关键词： antidepressants chronic pain depression exercise hippocampal neurogenesis inflammation inhibition neuroinflammation physical activity deficits social isolation spinal cord injury

Influences of Graupel Microphysics on Cma-GFS Simulation of Summer Regional Precipitation

在线全文

学校读者我要写书评

暂无评论

Journal of Meteorological Research 2024年第1期38卷 27-38页

作者： Zhe LI Qijun LIU Zhanshan ma Cma Earth System Modeling and Prediction Centre China Meteorological Administration(CMA)Beijing 100081

The horizontal resolution of global numerical weather prediction models is continuously developing. However, due to the imperfect precipitation simulation/forecast of these models, the demand for considering riming particles in cloud microphysical schemes in these models is increasing. This study employed the latest versions of global atmospheric reanalysis data (ERA5), the satellite retrieval data of the Global Precipitation Observation Program (GPM),and station precipitation observations to explore the impacts of adding graupel to the cloud microphysical scheme in the China Meteorological Administration-Global Forecast System (Cma-GFS) on summer regional precipitation simulations in four Chinese climate zones. The results verify that the new graupel scheme can enable Cma-GFS to decently predict global graupel distribution, especially in tropical and midlatitude regions. The addition of graupel in the cloud microphysics increases the precipitation simulation in North China, while that in Southwest China is weakened and dispersed. Moreover, graupel scheme increases the precipitation simulations of almost all *** increase in light rain is obvious, and the absolute value of heavy rain is strengthened. This may be because graupel quickly melts into rain after falling out of the zero-temperature layer due to its large mass and fast falling speed, increasing surface precipitation. In summary, the addition of graupel in the cloud microphysical scheme can improve Cma-GFS’s underestimation of strong precipitation.

关键词： graupel cloud microphysical scheme precipitation China Meteorological Administration-Global Forecast System(Cma-GFS) climate zone

Damage constitutive model of lunar soil simulant geopolymer under impact loading

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第3期16卷 1059-1071页

作者： Hanyan Wang Qinyong ma Qianyun Wu School of Civil Engineering and Architecture Anhui University of Science and TechnologyHuainan232001China Engineering Research Center of Underground Mine Construction Ministry of EducationAnhui University of Science and TechnologyHuainan232001China

Lunar base construction is a crucial component of the lunar exploration program,and considering the dynamic characteristics of lunar soil is important for moon ***,investigating the dynamic properties of lunar soil by establishing a constitutive relationship is critical for providing a theoretical basis for its damage *** this paper,a split Hopkinson pressure bar(SHPB)device was used to perform three sets of impact tests under different pressures on a lunar soil simulant geopolymer(LSSG)with sodium silicate(Na_(2)SiO_(3))contents of 1%,3%,5%and 7%.The dynamic stressestrain curves,failure modes,and energy variation rules of LSSG under different pressures were *** equation was modified based on the ZWT viscoelastic constitutive model and was combined with the damage *** damage element obeys the Weibull distribution and the constitutive equation that can describe the mechanical properties of LSSG under dynamic loading was *** results demonstrate that the dynamic compressive strength of LSSG has a marked strain-rate strengthening ***_(2)SiO_(3) has both strengthening and deterioration effects on the dynamic compressive strength of *** Na_(2)SiO_(3) grows,the dynamic compressive strength of LSSG first increases and then *** a fixed air pressure,5%Na_(2)SiO_(3) had the largest dynamic compressive strength,the largest incident energy,the smallest absorbed energy,and the lightest *** ZWT equation was modified according to the stress response properties of LSSG and the range of the SHPB strain rate to obtain the constitutive equation of the LSSG,and the model’s correctness was confirmed.

关键词： Lunar soil simulant geopolymer(LSSG) Split hopkinson pressure bar(SHPB)test Constitutive model Energy analysis Failure mode

Gastric cancer secreted miR 214-3p inhibits the anti-angiogenesis effect of apatinib by suppressing ferroptosis in vascular endothelial cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第3期32卷 489-502页

作者： WEIXUE WANG TONGTONG WANG YAN ZHANG TING deNG HAIYANG ZHANG YI ba department of GI Medical Oncology Tanjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin's Clinical Research Center for CancerTianjin Key Iaboratory of Digestive CancerKey Laboratory of Cancer Prevention and TherapyTianjin300060China

Diferent from necrosis,apoptosis,autophagy and other forms of cell death,ferroptosis is a mechanism that catalyzes lipid peroxidation of polyunsaturated ftty acids under the action of iron divalent or lipoxygenase,leading to cell *** is currently used in the third line standard treatment of advanced gastric cancer,targeting the anti-angiogenesis ***,Apatinib mediated ferroptosis in vascular endothelial cells has not been reported *** exosomes can be taken up into target cells to regulate tumor development,but the mechanism related to vascular endothelial cell ferroptosis has not yet been ***,we show that exosomes secreted by gastric cancer cells carry miR-214.3p into vascular endothelial cells and directdy target zinc finger protein A20 to negatively regulate ACSL4,a key enzyme of lipid peroxidation during frroptosis thereby inhibiting ferroptosis in vascular endothelial cells and reducing the eficiency of *** conclusion,inhibition of miR-214-3p can increase the sensitivity of vascular endothelial cells to Apatinib,thereby promoting the antiangiogenic efect of Apatinib,suggesting a potential combination therapy for advanced gastric cancer.

关键词： Cellular ferroptosis Exosome Tyrosine kinase inhibitor Gastrointestinal tumors miRNA

Twisted and Absolute degrees of maps into the Projective Plane

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta mathematica Sinica,English Series 2024年

作者： marcio Colombo FENILLE Daciberg lima GON?ALVES Universidade Federal de Uberlandia – Instituto de matemática e Estatística.Av.Jo?o Naves deávila 2121 Santa M?nica Universidade de S?o Paulo – Instituto de matemática e Estatística.Rua do mat?o 1010 Cidade Universitária

For each based map f : X → RP2from a closed surface into the real projective plane, we compute its absolute and twisted degrees and describe the action of the fundamental group of RP2over the based homotopy class of f. We emphasize the finding that for any nonorientable closed surface,there exists only one based homotopy class of maps from it into RP2whose maps have twisted degree zero and absolute degree nonzero – which shows that, unlike the absolute degree, the twisted degree is not able to detect the strong surjectivity in this setting. In all the other scenarios, the absolute degree of each map is either equal to the twisted degree or its absolute value – and so the twisted degree detects strong surjectivity.

关键词：

Reassessing the contributions of terrestrial waters to sea level variations in the South China Sea and its response to alternating ENSO events

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2024年第7期67卷 2253-2267页

作者： Pengfei YANG Hok Sum FOK Zhongtian ma MOE Key Laboratory of Geospace Environment and Geodesy&MNR Key Laboratory of Geophysical Geodesy School of Geodesy and GeomaticsWuhan UniversityWuhan 430079China Hubei Luojia Laboratory Wuhan 730079China department of Land Surveying and Geo-Informatics The Hong Kong Polytechnic UniversityHong Kong 999077China

Regional sea level variability is linked to regional terrestrial water and the El Ni?o-Southern Oscillation(ENSO).This study assessed the relationships between the sea level variations in the South China Sea(SCS)and ENSO,the impact of terrestrial water storage(TWS)on non-steric sea level(NSSL),and the contributions of steric sea level(SSL)and NSSL to sea level anomaly(SLA),*** 2003 to 2015,the SLAs exhibited a long-term trend of 6.65±0.78 mm/yr,which was primarily attributed to the ***,during 2003-2015,ENSO events alternating with varying intensities might also be responsible for the unusually high SLA *** to the SSLs,the NSSLs contributed the seasonal signals to the SLAs,while the NSSLs changes were largely explained by the TWS in the Mekong River basin at the seasonal scale and in the Pearl River basin and Red River basin at other time *** contrast to the TWS,the contributions of precipitation and evapotranspiration were relatively minor.A negative correlation between the sea level variations and ENSO was also found,with cross-correlation coefficients between the oceanic Ni?o index and SLAs/SSLs/NSSLs of -0.36/-0.37/-0.62 with lags of 2/3/2 months,*** findings systematically reassessed the contributions of different components to the sea level *** study provided a benchmark for in-depth analysis of the impacts of terrestrial water and other potential causes on sea level rise in the SCS.

关键词： South China Sea Sea level variations Terrestrial water storage ENSO

同方期刊数据库

deciphering and integrating invariants for neural operator learning with various physical mechanisms

在线全文

学校读者我要写书评

暂无评论

National Science Review 2024年第4期11卷 111-122页

作者： Rui Zhang Qi Meng Zhi-Ming ma Academy of mathematics and Systems Science Chinese Academy of Sciences(CAS) Microsoft Research

Neural operators have been explored as surrogate models for simulating physical systems to overcome the limitations of traditional partial differential equation(Pde) solvers. However, most existing operator learning methods assume that the data originate from a single physical mechanism, limiting their applicability and performance in more realistic scenarios. To this end, we propose the physical invariant attention neural operator(PiaNO) to decipher and integrate the physical invariants for operator learning from the Pde series with various physical mechanisms. PiaNO employs self-supervised learning to extract physical knowledge and attention mechanisms to integrate them into dynamic convolutional *** to existing techniques, PiaNO can reduce the relative error by 13.6%–82.2% on Pde forecasting tasks across varying coefficients, forces or boundary conditions. Additionally, varied downstream tasks reveal that the PI embeddings deciphered by PiaNO align well with the underlying invariants in the Pde systems, verifying the physical significance of PiaNO.

关键词： neural operator Pde solver contrastive learning physical invariants

development and validation of a prognostic immunoinflammatory index for patients with gastric cancer

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第24期30卷 3059-3075页

作者： Zhi-Chang ba Xi-Qing Zhu Zhi-Guo Li Yuan-Zhou Li department of Radiology Harbin Medical University Cancer HospitalHarbin 150081Heilongjiang ProvinceChina department of Gastrointestinal Surgery Harbin Medical University Cancer HospitalHarbin 150081Heilongjiang ProvinceChina

baCKGROUND Studies have demonstrated the influence of immunity and inflammation on the development of *** single biomarkers of immunity and inflam-mation have been shown to be clinically predictive,the use of biomarkers integrating both to predict prognosis in patients with gastric cancer remains to be *** To investigate the prognostic and clinical significance of inflammatory biomarkers and lymphocytes in patients undergoing surgical treatment for gastric *** Univariate COX regression analysis was performed to identify potential prognostic factors for patients with gastric cancer undergoing surgical *** absolute shrinkage and selection operator-COX(LASSO-COX)regression analysis was performed to integrate these factors and formulate a new prognostic immunoinflammatory index(PII).The correlation between PII and clinical charac-teristics was statistically *** incorporating the PII score were devised and validated based on the time-dependent area under the curve and decision curve *** Patients exhibiting elevated neutrophil-to-lymphocyte ratio,platelet-to-lymphocyte ratio,and systemic immune inflammatory index displayed inferior progression-free survival(PFS)and overall survival(OS).Conversely,low levels of CD3(+),CD3(+)CD8(+),CD4(+)CD8(+),and CD3(+)CD16(+)CD56(+)T lymphocytes were associated with improved PFS and OS,while high CD19(+)T lymphocyte levels were linked to worse PFS and *** PII score demonstrated associations with tumor characteristics(primary tumor site and tumor size),establishing itself as an independent prognostic factor for both PFS and ***-dependent area under the curve and decision curve analysis affirmed the effectiveness of the PII-based nomogram as a robust prognostic predictive *** PII may be a reliable predictor of prognosis in patients with gastric cancer undergoing surgical treatment,and it offers insights into cancer-related immune-inflammatory re

关键词： Gastric cancer Immunity Inflammation Prognosis Nomogram