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Effect of long-term Helicobacter pylori infection on growth of children:a cohort study

World Journal of Pediatrics 2016年第2期12卷 196-201页

作者： Celebi Kocaoglu Ahmet Ozel Mustafa Cayci ece selma solak Department of Pediatrics Konya Education and Research Hospital42090 MeramKonyaTurkey Department of Pediatric Nephrology Konya Education and Research Hospital42090 MeramKonyaTurkey Department of Nuclear Medicine Konya Education and Research Hospital42090 MeramKonyaTurkey

Background:The effects of Helicobacter pylori(***)infection on growth are a controversial *** investigated the effects of long-term *** infection on height and weight in ***:A total of 200 children of 7-18 years old suffering from dyspeptic complaints were classified into two groups:*** positive and negative groups,*** the infection was impoved was followed up while performing urea breath test,and according to exposure time to the infection,the children were further divided into group 1(≤1.5 months),group 2(>1.5-≤6 months)and group 3(>6 months).Antropometric measurements were obtained and repeated every six ***:Mean growth velocity scores in the *** positive and negative groups were 0.49±3.85[95%confidence interval(CI):-0.21-1.18]and 1.98±4.42(95%CI:1-2.96),*** difference between both groups was statistically significant(P=0.012).Mean growth velocity scores in groups 1,2 and 3 were 0.96±3.84,0.16±4.51 and-0.85±3.09,*** growth velocity scores of group 3 were significantly lower than those of groups 0 and 1(P=0.005 and P=0.041).The mean weight scores in group 3 were similar to those in group 2,but the scores in group 3 were signifi cantly lower than those in group 1(-1.75±1.05,-1.21±1.37 and-0.88±1.49,respectively).Conclusion:As the duration of exposure is prolonged in children with *** infection,the negative effect of the infection on both height and weight is evident.

关键词： antropometry failure to thrive growth velocity Helicobacter pylori

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A case of Bruton’s disease presenting with recurrent pneumonia

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Case Reports in Clinical Medicine 2013年第6期2卷 338-340页

作者： Fatih Akin Saltuk Bugra Boke ece selma solak Cengizhan Kilicaslan Sukru Arslan Department of Pediatrics Konya Education and Research HospitalKonyaTurkey Department of Pediatric Nephrology Konya Education and Research HospitalKonyaTurkey

X-linked agammaglobulinemia also known as Bruton’s disease, is a humoral immunodeficiency disease characterized by recurrent bacterial infections due to low levels or absence of serum immunoglobulins. It has been shown to be caused by mutations in the gene encoding Bruton tyrosine kinase. Although bacterial infections typically begins 6-9 months after birth when maternal IgG is reduced below the protective level, the diagnosis is established before 5 years of age. Here we report a case with Bruton’s disease and recurrent pneumonia?that is typical of the late diagnosed disease. This report suggests the importance of evaluating patients with recurrent infections for immunodeficiency diseases.

关键词： X-Linked Agammaglobulinemia Recurrent Pneumonia Immunodeficiency

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