检索结果-南通市图书馆

Enhancing pedestrian mobility in Smart Cities using Big Data

Journal of Management Analytics 2020年第2期7卷 173-188页

作者： ebony carter Patrick Adam Deon Tsakis Stephanie Shaw Richard Watson Peter Ryan Faculty of Business and Law Swinburne UniversityHawthornAustralia Swinburne University of Technology Defence Science&Technology Group MelbourneAustralia

Smart City is an emerging concept in global urban development.A Smart City applies ICT technologies to provide greater efficiencies for its urban areas and civilian *** of the key requirements for a Smart City is to exploit data from its ICT infrastructure(such as Internet of Things connected sensors)to improve city services and features such as accessibility and *** address this requirement,the City of Melbourne(COM)Smart City office maintains several hundred data sets relating to urban activity and *** datasets address parking,mobility,land use,3D data,statistics,environment,and major city developments such as rail *** promising dataset relates to pedestrian *** are obtained from sensors and updated on the COM website(City of Melbourne Open Data Platform:https://***/.)at regular *** data include the number of pedestrians passing 53 specific locations in the central business district and also their times and directions of *** a 24 h period,over 650,000 pedestrians were counted passing all *** rates of several thousand pedestrians per minute are regularly recorded during city rush hours at hotspots making the data amenable to Big Data analysis *** are obtained in graphical format as heatmaps and charts of city pedestrian traffic using both Microsoft Excel^(■)for static analysis and PowerBI^(■)for more advanced interactive visualisation and *** findings can identify pedestrian hotspots and inform future locations of traffic lights and street configurations to make the city more pedestrian ***,the experience gained can be used to examine other data sets such as bicycle traffic that can be analysed to inform city infrastructure *** work is suggested that could link these pedestrian flow data with social media data from smartphones and potentially wearable devices such as fitness monitors to correlate pedestrian s

关键词： Internet of Things Smart Cities Big Data analytics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The dark fantastic

The dark fantastic

引用

作者： ebony Elizabeth Thomas.

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Synergistic effects of methyl 2-cyano-3,11-dioxo-18beta-olean-1,-12-dien-30-oate and erlotinib on erlotinib-resistant non-small cell lung cancer cells

引用

Journal of Pharmaceutical Analysis 2021年第6期11卷 799-807页

作者： ebony Nottingham Elizabeth Mazzio Sunil Kumar Surapaneni Shallu Kutlehria Arindam Mondal Ramesh Badisa Stephen Safe Arun K.Rishi Mandip Singh Department of Pharmaceutics College of Pharmacy and Pharmaceutical SciencesFlorida A&M UniversityTallahasseeFL32307USA Department of Veterinary Physiology and Pharmacology College of Veterinary MedicineTexas A&M UniversityCollege StationTX77843USA John D.Dingell VA medical Center and Department of Oncology Wayne State UniversityDetroitMI48201USA

Non-small cell lung cancer(NSCLC)is often characterized by an underlying mutation in the epidermal growth factor receptor(EGFR),contributing to aggressive metastatic *** 2-cyano-3,11-dioxo-18 beta-olean-1,12-dien-30-oate(CDODA-Me),a glycyrrhetinic acid derivative,reportedly improves the therapeutic response to erlotinib(ERL),an EGFR tyrosine kinase *** the present study,we performed a series of studies to demonstrate the efficacy of CDODA-Me(2μM)in sensitizing HCC827 R(ERL-resistant)cells to ***,we first established the selectivity of ERL-induced drug resistance in the HCC827 R cells,which was sensitized when ERL was combined with CDODA-Me(2μM),shifting the IC50 from 23.48μM to 5.46μ***,whole transcriptomic microarray expression data demonstrated that the combination of ERL+CDODA-Me elicited 210 downregulated genes(0.44%of the whole transcriptome(WT))and 174 upregulated genes(0.36%of the WT),of which approximately 80%were unique to the ERL+CDODA-Me *** effects centered on losses to cell cycle progression transcripts,a reduction of minichromosome maintenance complex components(MCM2-7),all key components of the Cdc45·MCM2-7 GINS(CMG)complex,and replicative helicases;these effects were tantamount to the upregulation of processes associated with the nuclear factor erythroid 2 like 2 translational response to oxidative stress,including sulfiredoxin 1,heme oxygenase 1,and stress-induced growth inhibitor ***,these findings indicate that the synergistic therapeutic effects of ERL+CDODA-Me on resistant NSCLC cells are mediated via the inhibition of mitosis and induction of oxidative stress.

关键词： Transcriptomic analysis Combination therapy Drug resistance Erlotinib Epidermal growth factor receptor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Predation risk assessment based on uncertain information: interacting effects of known and unknown cues

引用

Current Zoology 2019年第1期65卷 75-76页

作者： Laurence E. A. Feyten ebony E. M. Demers Indar W. Ramnarine Grant E. Brown Department of Biology Concordia University 7141 Sherbrooke Streeet West Montreal Quebec Canada H4B 1R6 Department of Life Sciences University of the West Indies St. Augustine Trinidad and Tobago

Prey use reliable public information in order to assess local habitat condirions such as predation risks, competitive interactions, and foraging opportunities (Dall et al. 2005), allowing for context appropriate behavioral decisions. However, public information can often differ widely in reliability (Feyten and Brown 2018), increasing the potential costs associated with behavioral decision making (Dall et al. 2005). The reliability of public information is expected to decrease with in creased un certainty of environmental conditio ns (Koops 2004;Dall et al. 2005), where ecological uncertainty is the ambiguity about the current state of the environment due to imperfect or incomplete information (Dall et al. 2005;Munoz and Blumstein 2012;Feyten and Brown 2018).

关键词： Prey environmental conditio

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

通道无限

引用

美苑 2010年第3期 110-112页

作者： David ebony 艾雯(译) 不详东北大学外语学院

与八年前位于毕尔巴鄂的古根海姆博物馆首度开馆时相比,今年夏天弗兰克·盖里的再度设计似乎更夸张且令人难忘。对于毕尔巴鄂这样一个平淡无奇的西班牙北部港口城市来说,八年前的那种结构设计确实有些突兀,但时至今日,新建博物馆那些弯... 详细信息

与八年前位于毕尔巴鄂的古根海姆博物馆首度开馆时相比,今年夏天弗兰克·盖里的再度设计似乎更夸张且令人难忘。对于毕尔巴鄂这样一个平淡无奇的西班牙北部港口城市来说,八年前的那种结构设计确实有些突兀,但时至今日,新建博物馆那些弯曲的悬臂和闪闪发光的钛金属包裹与周围环境仿佛已融为一体，并与远处依稀可辨的巴斯克乡村起伏翠绿的山丘相呼应。

关键词：古根海姆博物馆通道毕尔巴鄂结构设计港口城市弗兰克西班牙巴斯克

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：