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Bayesian network model to distinguish between intentional attacks and accidental technical failures:a case study of floodgates

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Cybersecurity 2021年第1期4卷 442-460页

作者： Sabarathinam Chockalingam Wolter Pieters andréTeixeira Pieter van Gelder Faculty of Technology Policy and ManagementDelft University of TechnologyDelftThe Netherlands Department of Risk Safety and SecurityInstitute for Energy TechnologyHaldenNorway Behavioural Science Institute Radboud UniversityNijmegenThe Netherlands Department of Electrical Engineering Uppsala UniversityUppsalaSweden

Water management infrastructures such as floodgates are critical and increasingly operated by Industrial Control Systems(ICS).These systems are becoming more connected to the internet,either directly or through the corporate *** makes them vulnerable to *** behaviour in floodgates operated by ICS could be caused by both(intentional)attacks and(accidental)technical *** operators notice abnormal behaviour,they should be able to distinguish between those two causes to take appropriate measures,because for example replacing a sensor in case of intentional incorrect sensor measurements would be ineffective and would not block corresponding the attack *** the previous work,we developed the attack-failure distinguisher framework for constructing Bayesian Network(BN)models to enable operators to distinguish between those two causes,including the knowledge elicitation method to construct the directed acyclic graph and conditional probability tables of BN *** a full case study of the attack-failure distinguisher framework,this paper presents a BN model constructed to distinguish between attacks and technical failures for the problem of incorrect sensor measurements in floodgates,addressing the problem of floodgate *** utilised experts who associate themselves with the safety and/or security community to construct the BN model and validate the qualitative part of constructed BN *** constructed BN model is usable in water management infrastructures to distinguish between intentional attacks and accidental technical failures in case of incorrect sensor *** could help to decide on appropriate response strategies and avoid further complications in case of incorrect sensor measurements.

关键词： Bayesian network DeMorgan model Intentional attack Probability elicitation Safety Security Technical failure Water management

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Grazing Pressure and Plant Functional Types in Puna Highlands,Northwestern Argentina

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Phyton-International Journal of Experimental Botany 2024年第5期93卷 1067-1080页

作者： Quiroga Mendiola Mariana Tálamo andrés IPAF NOA—INTA(National Institute for Agricultural Technology) Posta de HornillosJujuy4622Argentina Facultad de Ciencias Naturales Universidad Nacional de SaltaSalta4400Argentina Instituto de Bio y Geociencias del NOA(IBIGEO) UNSa-CONICET.Laboratorio de Ecología Aplicada a la Conservación(LEAC)Facultad de Ciencias NaturalesUniversidad Nacional de SaltaSalta4400Argentina Maestría en Gestión Ambiental Escuela de NegociosUniversidad Católica de Salta(UCASAL)Salta4400Argentina

The Puna grasslands support grazing systems that produce meat and wool in multi-species herds,especially from llama(Lama glama)and ***,it is yet unknown whether grazing pressure can modify grassland structure and Plant Functional Types diversity and cover in Puna *** analyzed the relationship between grazing pressure and Plant Functional Types by comparing transects located near stockyards(high grazing pressure)and far from them(low pressure)and by evaluating the relationship between the Plant Functional Types cover to a Grazing Pressure Index(GPI).This index incorporates the heterogeneity of traditional pastoral *** two ecological sites(Ciénego and Tolar),we sampled paired transects(near-far).Plots near and far from corrals were similar in all the variables measured except for plots in Tolar,which tend to have higher total cover,possibly due to fecal fertilization near ***,we recorded an increase in total cover and grass cover at higher GPI in Ciénego,while in Tolar we found lower values of total cover and herbaceous dicotyledonous cover at intermediate intensities of *** only negative relationship found was the cover of clonal and non-clonal shrubs,possibly explained by the greater use of these shrubs as firewood near *** summary,our study does not show important changes in Plant Functional Types as a function of grazing pressure in the studied grasslands probably because grazing pressure is diluted or diminished when livestock rotates in different areas and grazing durations ***,the long grazing history with which the Puna has evolved could also contribute to the co-structuration between native vegetation and livestock farming.

关键词： Natural grasslands Puna herbivory ecological perturbation

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Ad Hoc File Systems for High-Performance Computing

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Journal of Computer Science & Technology 2020年第1期35卷 4-26页

作者： andréBrinkmann Kathryn Mohror Weikuan Yu Philip Carns Toni Cortes Scott A.Klasky Alberto Miranda Franz-Josef Pfreundt Robert B.Ross Marc-andréVef Zentrum für Datenverarbeitung Johannes Gutenberg University MainzMainz 55128Germany Center for Applied Scientific Computing Lawrence Livermore National LaboratoryLivermoreCA 94550U.S.A Department of Computer Science Florida State UniversityTallahasseeFL 32306U.S.A Mathematics and Computer Science Division Argonne National LaboratoryLemontIL 60439U.S.A Department of Computer Architecture Universitat Politecnica de CatalunyaBarcelona 08034Spain Computer Science and Mathematics Division Oak Ridge National LaboratoryOak RidgeTN 37831U.S.A Computer Science Department Barcelona Supercomputing CenterBarcelona 08034Spain Fraunhofer Institute for Industrial Mathematics ITWM Fraunhofer-Platz 1Kaiserslautern 67663Germany

Storage backends of parallel compute clusters are still based mostly on magnetic disks,while newer and faster storage technologies such as flash-based SSDs or non-volatile random access memory(NVRAM)are deployed within compute *** these new storage technologies into scientific workflows is unfortunately today a mostly manual task,and most scientists therefore do not take advantage of the faster storage *** approach to systematically include nodelocal SSDs or NVRAMs into scientific workflows is to deploy ad hoc file systems over a set of compute nodes,which serve as temporary storage systems for single applications or longer-running *** paper presents results from the Dagstuhl Seminar 17202"Challenges and Opportunities of User-Level File Systems for HPC"and discusses application scenarios as well as design strategies for ad hoc file systems using node-local storage *** discussion includes open research questions,such as how to couple ad hoc file systems with the batch scheduling environment and how to schedule stage-in and stage-out processes of data between the storage backend and the ad hoc file *** presented are strategies to build ad hoc file systems by using reusable components for networking and how to improve storage device *** interfaces and semantics are presented,for example those used by the three ad hoc file systems BeeOND,GekkoFS,and *** presentation covers a range from file systems running in production to cutting-edge research focusing on reaching the performance limits of the underlying devices.

关键词： parallel architectures distributed file system high-performance computing burst buffer POSIX(portable operating system interface)

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Cyano-containing ionic liquids for the extraction of aromatic hydrocarbons from an aromatic/aliphatic mixture

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Science China Chemistry 2012年第8期55卷 1488-1499页

作者： MEINDERSMA G. Wytze DE HAAN andré B. Department of Chemical Engineering & Chemistry Eindhoven University of Technology

Ionic liquids can replace conventional solvents in aromatic/aliphatic extractions, if they have higher aromatic distribution coef- ficients and higher or similar aromatic/aliphatic selectivities. Also physical properties, such as density and viscosity, must be taken into account if a solvent is applied in an industrial extraction process. Cyano-containing ionic liquids have a lower den- sity than the benchmark solvent sulfolane and a higher viscosity. Sulfolane is from a hydrodynamic point of view a better sol- vent than ionic liquids for the aromatic/aliphatic extraction. The most suitable ionic liquids for the extraction of aromatic hy- drocarbons from a mixture of aromatic and aliphatic hydrocarbons are [bmim]C(CN)3, [3-mebupy]N(CN)2, [3-mebupy]C(CN)3, [3-mebupy]B(CN)4 and [mebupyrr]B(CN)4. They have factors of 1.2-2.3 higher mass-based distribution coefficients than sul- folane and a similar or higher, up to a factor of 1.9 higher, aromatic/aliphatic selectivity than sulfolane. The IL [3-mebupy]N(CN)2 is a better extractant for the separation of toluene from a mixture of toluene/n-heptane in a pilot plant Ro- tating Disc Contactor (RDC) than sulfolane.

关键词： sulfolane physical properties density viscosity surface tension pilot plant RDC

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Laser Measurements in High Speed Compressors for Rotor-Stator Interaction Analysis

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Journal of Thermal Science 2003年第4期12卷 310-317,309页

作者： Xavier Ottavy Isabelle Trébinjac andré Vouillarmet David Arnaud Laboratoire de Mecanique des Fluides et d'Acoustique UMR CNRS 5509/ECL/UCB Lyon I Ecole Centrale de Lyon 36 Avenue Guy de Collongue 69134 ECULLY Cedex France

This paper deals with the experimental quantification of the unsteady effects of the interactions between rotor and stator rows in high speed compressors. Due to the fact that the levels of the periodic fluctuations arising from the unsteady interaction may be low compared with the random fluctuations arising from the measurement uncertainties, it is crucial to minimize the errors inherent to the used technique. The first part of the paper concentrates on technical details relative to the experimental process. The second part is devoted to the data post-processing. Two tools for analysing the rotor-stator interactions are presented. The first tool is based on a decomposition of the flow field which was initially introduced to solve numerical problems when attempting to calculate the flow field in a multi-row configuration. The second tool is based on a spectral analysis of the signal, that qualifies the interaction in a sense of circumferential spinning lobes. Experimental results obtained within both an axial and a centrifugal high speed compressors are used to illustrate the data processing. In both cases, the effects of the unsteady interaction are quantified.

关键词： laser anemometry high speed compressor rotor-stator interaction.

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Trends in lactose-derived bioactives:synthesis and purification

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Systems Microbiology and Biomanufacturing 2022年第3期2卷 393-412页

作者： Carlos Vera Cecilia Guerrero andrés Illanes Department of Biology Faculty of Chemistry and BiologyUniversidad de Santiago de Chile(USACH)SantiagoChile School of Biochemical Engineering Pontificia Universidad Católica de Valparaíso(PUCV)ValparaisoChile

Lactose obtained from cheese whey is a low value commodity despite its great potential as raw material for the production of bioactive *** them,prebiotics stand out as valuable ingredients to be added to food matrices to build up functional foods,which currently represent the most active sector within the food *** foods market has been growing steadily in the recent decades along with the increasing awareness of the World population about healthy nutrition,and this is having a strong impact on lactose-derived *** of them are produced by enzyme biocatalysis because of molecular precision and environmental sustainability *** current status and outlook of the production of lactose-derived bioactive compounds is presented with special emphasis on downstream operations which are critical because of the rather modest lactose conversion and product yields that are *** though some of these products have already an established market,there are still several challenges referring to the need of developing better catalysts and more cost-effective downstream operations for delivering high quality products at affordable *** technological push is expected to broaden the spectrum of lactose-derived bioactive compounds to be produced at industrial scale in the near future.

关键词： Prebiotic Lactose β-Galactosidase Oligosaccharide purification

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Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity

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Bioactive Materials 2023年第6期24卷 174-184页

作者： andrés García-García Sébastien Pigeot Ivan Martin Department of Biomedicine University Hospital BaselUniversity of Basel4031BaselSwitzerland Department of Biomedical Engineering University of Basel4123AllschwillSwitzerland

The increasing recognition of the contribution of the immune system to activate and prime regeneration implies that tissue engineering strategies and biomaterials design should target regulation of early immunological *** previously proposed the cell-based engineering and devitalization of extracellular matrices(ECMs)as a strategy to generate implant materials delivering custom-defined ***,in the context of bone regeneration,we aimed at enhancing the osteoinductivity of such ECMs by enriching their immunomodulatory factors *** with IL1βa cell line overexpressing BMP-2 enabled engineering of ECMs preserving osteoinductive signals and containing larger amounts of angiogenic(VEGF)and pro-inflammatory molecules(IL6,IL8 and MCP1).Upon implantation,these IL1β-induced materials enhanced processes typical of the inflammatory phase(e.g.,vascular invasion,osteoclast recruitment and differentiation),leading to‘regenerative’events(e.g.,M2 macrophage polarization)and ultimately resulting in faster and more efficient bone *** results bear relevance towards the manufacturing of potent off-the-shelf osteoinductive materials and outline the broader paradigm of engineering immunoinstructive implants to enhance tissue regeneration.

关键词： Immunomodulation Bone tissue engineering Inflammation Hypertrophic cartilage matrices Osteoinduction

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On the role of RNA binding proteins in polyglutamine diseases:from pathogenesis to therapeutics

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Neural Regeneration Research 2023年第12期18卷 2695-2696页

作者： andréConceição Rebekah Koppenol Clévio Nóbrega Algarve Biomedical Center Research Institute(ABC-RI) FaroPortugalFaculdade de Medicina e Ciências BiomédicasUniversidade do AlgarveFaroPortugal PhD Program in Biomedical Sciences Faculdade de Medicina e Ciências BiomédicasUniversidade do AlgarveFaroPortugalCenter for Neuroscience and Cell BiologyUniversity of CoimbraPortugal

Polyglutamine(polyQ) diseases are a group of different neurodegenerative disorders characterized by an abnormal expansion of the trinucleotide cytosine-adenine-guanine(CAG)within coding regions of each disease-associa... 详细信息

关键词： diseases pathogenesis translate

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Anthropomorphism Indexes of the Kinematic Chain for Artificial Hands

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Journal of Bionic Engineering 2020年第3期17卷 501-511页

作者： Immaculada Llop-Harillo Antonio Pérez-González Javier andrés-Esperanza Grupo de Biomecdnicay Ergonomia Departamento de Ingenieria Mecdnicay Construccidny Universitat Jaume I(UJI)Castelldn 12071Spain

Anthropomorphic hands have received increasing research interest in the fields of robotics and *** it is not yet clear how to evaluate their *** in the kinematic chain is essential to achieve both functionality and cosmesis.A few previous works have addressed the definition of anthropomorphism indexes,although they have some limitations in its *** this study,three different anthropomorphism indexes have been defined to compare the kinematic chain of artificial hands with that of the human *** indexes are based on the comparison of:(I)the parameters of the kinematic chain(dimensions,type of joints,orientations and ranges of motion),(2)the reachable workspace,and(3)common grasping *** artificial hands with different degrees of anthropomorphism have been compared using the three Anthropomorphism Indexes of the Kinematic Chain(AIKC).The results show a high correlation between the first and third AIKC for the hands *** second AIKC presents much lower values than the other two,although they are higher for hands that combine abduction/adduction and flexion/extension movements in the kinematic chain of each *** indexes can be useful during the initial stage of designing artificial hands or evaluating their anthropomorphism.

关键词： anthropomorphism grasping indexes kinematics multifingered hands

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Importance of defining the best treatment of a genital gunshot wound: A case report

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World Journal of Clinical Cases 2014年第10期2卷 587-590页

作者： Herney andrés García-Perdomo School of Medicine Faculty of Health University of Valle

Twenty percent of genital traumas are caused by penetrating injuries; accordingly gunshot and stab wounds have increased in the last couple of years around the globe, even in Colombia. A 67-year-old male patient was admitted to the emergency room because he received multiple gunshot wounds. On physical examination, multiple wounds on his penis with loss of tissue in the foreskin, glans, anterior urethra(distal third) and cavernous corpora were found. The urologist performed a partial penectomy with a penis reconstruction, he debrided the cutaneous flap of the dorsal foreskin and its glans, sutured the distal cavernous corpora and dissected the urethra. Penetrating genital injuries are extremely important due to their impact on the functional, psychological and the aesthetic consequences. It is necessary to define the best possible treatment to minimize the damage.

关键词： Genital Penile Injuries Trauma Amputation

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