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Clinical and Microbiological Characteristics of Patients with Complicated Intra-abdominal Infections in Intensive Care Unit

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Current Medical Science 2020年第1期40卷 104-109页

作者： Yang-mei XIONG Xin rao Department of Intensive Care Unit Zhongnan Hospital of Wuhan UniversityWuhan 430071China

In order to investigate the clinical and microbiological characteristics of patients with complicated intra-abdominal infections(cIAIs)in intensive care unit(ICU),the clinical data of 612 cIAIs patients from January 2016 to December 2018 were retrospectively *** characteristics,distribution of pathogens and drug resistance were statistically *** was found that patients with community-acquired intra-abdominal infections(CA-IAIs)made up a majority of cIAIs *** positive rate of abdominal drainage fluid culture was 55.56%.Gramnegative bacteria accounted for the majority,the most commonly isolated bacteria of which were escherichia coli(20.96%),Klebsiella pneumoniae(10.20%)and Pseudomonas aeruginosa(5.57%).The most commonly isolated gram-positive bacteria were enterococcus(16.88%)and Methicillinresistant staphylococcus aureus(MRSA,3.90%).enterobacter isolates showed high resistance rate to most cephalosporins and low resistance rate to piperacillin/tazobactam and *** spectrum beta-lactamase(eSBL)screen positive isolates from CA-IAIs patients showed an increasing trend in past three *** and MRSA showed high resistance rate to clindamycin,quinolone,erythromycin and tetracycline,while they showed high sensitivity rate to linezolid,tegacycline,teicoplanin and *** results indicate that isolated bacteria from abdominal drainage fluid show high resistance rates to commonly used antibiotics in ICU patients with *** curative effects on diseases should be monitored continuously when antibiotics are ***,we should always keep eyes on drug-resistant bacteria,especially when the treatment efficacy is not good.

关键词： complicated intra-abdominal infection pathogens extended spectrum beta-lactamase screen positive isolates resistance rate

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Single photon emitter deterministically coupled to a topological corner state

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Light(Science & Applications) 2024年第1期13卷 135-141页

作者： Mujie rao Fulong Shi Zhixuan rao Jiawei Yang Changkun Song Xiaodong Chen Jianwen Dong Ying Yu Siyuan Yu State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information TechnologySchool of PhysicsSun Yat-Sen UniversityGuangzhou 510006China Hefei National Laboratory Hefei 230088China

Incorporating topological physics into the realm of quantum photonics holds the promise of developing quantum light emitters with inherent topological robustness and immunity to ***,the deterministic interaction of quantum emitters with topologically nontrivial resonances remains largely *** we present a single photon emitter that utilizes a single semiconductor quantum dot,deterministically coupled to a second-order topological corner state in a photonic crystal *** investigating the Purcell enhancement of both single photon count and emission rate within this topological cavity,we achieve an experimental Purcell factor of Fp=***,we demonstrate the on-demand emission of polarized single photons,with a second-order autocorrelation function g(2)(0)as low as 0.024±*** approach facilitates the customization of light-matter interactions in topologically nontrivial environments,thereby offering promising applications in the field of quantum photonics.

关键词： topological quantum deterministic

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In-vitro Androgenesis in Rice： Advantages, Constraints and Future Prospects

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Rice science 2016年第2期23卷 57-68页

作者： Rukmini MISHRA Gundimeda Jwala Narashima rao Centre of Biotechnology Siksha O Anusandhan University Bhubaneswar 751003 India Reid Road Point Fortin Trinidad & Tobago 150113 West Indies

In vitro androgenesis is an important component of plant biotechnology when the pollen grains are forced to switch from their normal pollen developmental pathway towards an embryogenic route. Haploid and doubled haploid produced through androgenesis have long been recognized as a valuable tool in plant breeding as it can shorten the breeding cycle, fix agronomic characters in homozygous state and enhance the selection efficiency of useful recessive agronomic traits. Recently, doubled haploids have been largely recognized as an important component of crop improvement through genome mapping, quantitative trait locus analysis, and genetic mutation, and as targets for genetic transformation programs. Thus, this review is focused mainly on various facets of doubled haploid in the chief staple food crop rice and sights its recent applications in plant breeding, genetics and genomics.

关键词： in vitro androgenesis doubled haploid haploid rice

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Chemical reaction effects on unsteady MHD flow past semi-infinite vertical porous plate with viscous dissipation

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Applied Mathematics and Mechanics(english edition) 2011年第8期32卷 1065-1078页

作者： J.A.rao S.SHIVAIAH Department of Mathematics Osmania University Department of Mathematics Padmasri Dr.B.V.Raju Institute of Technology

The chemical reaction effect on an unsteady magnetohydrodynamic （MHD） flow past a semi-infinite vertical porous plate with viscous dissipation is analyzed. The governing equations of motion, energy, and species are transformed into ordinary differential equations （ODes） using the time dependent similarity parameter. The resultant ODes are then solved numerically by a finite element method. The effects of various parameters on the velocity, temperature, and concentration profiles are presented graphically, and the values of the skin-friction, Nusselt number, and Sherwood number for various values of physical parameters are presented through tables.

关键词： magnetohydrodynamic (MHD) chemical reaction porous medium viscous dissipation finite element method

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engineered Wood/Bamboo Laminated Composites for Outdoor Hydrophilic Platforms:Structural Design and Performance

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Journal of Renewable Materials 2022年第9期10卷 2477-2487页

作者： Lifeng Ji Qiuxia Zhang Fei rao School of Art and Design Zhejiang Sci-Tech UniversityHangzhou310018China

Landscape designers increasingly prefer to use wood/bamboo-based composites for outdoor hydrophilic platforms owing to their natural surface texture,high performance,and sustainability to facilitate extensive interaction between people and water and enable the full range of ecological functions of water *** this study,four laminated composite(LC)structures were designed and manufactured using fluffed bamboo and wood *** surface textures,profile densities,water resistances,and mechanical properties were then *** type of fluffed veneer of the surface layer determined the texture of the LC *** specific structures of fluffed bamboo and wood veneer laminations were found to affect the LC profile density variability,water resistance,and mechanical properties owing to the differences in the strength and interfacial properties of bamboo and wood ***,the water resistance and mechanical properties of all four LCs were found to be much higher than the highest level specified in GB/T 20241-2006 for“laminated veneer lumber”and GB/T 30364-2013 for“bamboo scrimber flooring”,indicating that they are promising materials for structures and flooring,particularly for outdoor hydrophilic platforms.

关键词： Wood/bamboo laminated composites outdoor hydrophilic platform surface texture water resistance mechanical properties

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Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease

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Chinese Journal of Integrative Medicine 2018年第6期24卷 403-405页

作者： GUO Chuan rao XIANG-rong Department of Nephrology Guang'anmen HospitalChina Academy of Chinese Medical Sciences

Chronic kidney disease （CKD） is a major disease that threatens human health. With the progression of CKD, the risk of cardiovascular death increases, which is associated with the elevated levels of uremic toxins （UTs）. Representative toxins such as indoxyl sulfate and p-cresyl sulfate are involed in CKD progression and cardiovascular events inseparable from the key role of endothelial dysfunction. The therapeutic strategies of UTs are aimed at signaling pathways that target the levels and damage of toxins in modem medicine. There is a certain relevance between toxins and ＂turbid toxin＂ in the theory of Chinese medicine （CM）. CM treatments have been demonstrated to reduce the damage of gut-derived toxins to the heart, kidney and blood vessels. Modern medicine still lacks evidence-based therapies, so it is necessary to explore the treatments of CM.

关键词： chronic kidney disease uremic toxins therapeutic strategies Chinese medicine

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Multitarget Flexible Grasping Detection Method for Robots in Unstructured environments

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Computer Modeling in engineering & Sciences 2023年第11期137卷 1825-1848页

作者： Qingsong Fan Qijie rao Haisong Huang Key Laboratory of Modern Manufacturing Technology Ministry of EducationGuizhou UniversityGuiyang550025China

In present-day industrial settings,where robot arms performtasks in an unstructured environment,theremay exist numerousobjects of various shapes scattered in randompositions,making it challenging for a robot armtoprecisely attain the ideal pose to grasp the *** solve this problem,a multistage robotic arm flexible grasp detection method based on deep learning is *** method first improves the Faster RCNN target detection model,which significantly improves the detection ability of the model for multiscale grasped objects in unstructured ***,a Squeeze-and-excitation module is introduced to design a multitarget grasping pose generation network based on a deep convolutional neural network to generate a variety of graspable poses for grasped ***,a multiobjective IOU mixed area attitude evaluation algorithm is constructed to screen out the optimal grasping area of the grasped object and obtain the optimal grasping posture of the robotic *** experimental results show that the accuracy of the target detection network improved by the method proposed in this paper reaches 96.6%,the grasping frame accuracy of the grasping pose generation network reaches 94%and the flexible grasping task of the robotic arm in an unstructured scene in a real environment can be efficiently and accurately implemented.

关键词： Unstructured scene robot target detection grab pose detection deep learning

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extracting heartrate from optical signal of functional near-infrared spectroscopy based on mathematical morphology

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Journal of Innovative Optical Health Sciences 2018年第3期11卷 38-45页

作者： Jinyan Sun Linshang rao Chenyang Gao Department of Biomedical engineering Guangdong Medical University Dongguan 523808China School of Stomatology and Medicine Foshan University Foshan 528000China School of Biomedical engineering Southern Medical University Guangzhou 510515China Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology Wuhan 430074China

Functional near-infrared spectroscopy(fNIRS),as a new optical functional neuroimaging method,has been widely used in neuroscience *** some research fields with NIRS,heartrate(HR)(or heartbeat)is needed as useful information to evaluate its influence,or to know the state ofsubject,or to remove its *** HR(or heartbeat)can be detected with high accuracy from theoptical intensity,this will undoubtedly benefit a lot to many NIRS *** studies haveused the moving time window method or mathematical morphology method(MMM)to detectheartbeats in the optical ***,there are some disadvantages in these *** thisstudy,we proposed a method combining the periodic information of heartbeats and the operator ofmathematical morphology to automatically detect heartbeats in the optical *** theoptical intensity is smoothed using a moving average ***,the opening operator of math-ematical morphology extracts peaks in the smoothed optical ***,one peak is iden-tified as a heartbeat peak if this peak is the maximum in a predefined point *** on experimental data,our method can overcome the disadvantages of previous methods,and detet heartbeats in the optical signal of fNIRS with nearly 100%accuracy.

关键词： Funetional near-infrared spectroscopy heartrate mathematical morphology

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Next-Generation Plant Metabolic engineering, Inspired by an Ancient Chinese Irrigation System

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Molecular Plant 2018年第1期11卷 47-57页

作者： rao Fu Cathie Martin Yang Zhang Key Laboratory of Bio-resource and eco-environment of Ministry of education College of Life Sciences Sichuan University Chengdu 610064 China Department of Metabolic Biology John Innes Centre Norwich NR4 7UH UK

Specialized secondary metabolites serve not only to protect plants against abiotic and biotic challenges, but have also been used extensively by humans to combat diseases. Due to the great importance of medicinal plants for health, we need to find new and sustainable ways to improve the production of the specialized metabolites. In addition to direct extraction, recent progress in metabolic engineering of plants offers an alternative supply option. We argue that metabolic engineering for producing the second- ary metabolites in plants may have distinct advantages over microbial production platforms, and thus pro- pose new approaches of plant metabolic engineering, which are inspired by an ancient Chinese irrigation system. Metabolic engineering strategies work at three levels： introducing biosynthetic genes, using tran- scription factors, and improving metabolic flux including increasing the supply of precursors, energy, and reducing power. In addition, recent progress in biotechnology contributes markedly to better engineering, such as the use of specific promoters and the deletion of competing branch pathways. We propose that next-generation plant metabolic engineering will improve current engineering strategies, for the purpose of producing valuable metabolites in plants on industrial scales.

关键词： plant metabolic engineering secondary metabolites specialized metabolites transcription factor flux control multi-level engineering

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experimental evaluation of a 35 kVA downdraft gasifier

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Frontiers in energy 2013年第3期7卷 300-306页

作者： Ashok Jayawant rao KeCHe Gaddale AMBA PRASAD rao Department ol Mechanical englneenng National Institute of lecnnology Warangal 506004 (AP) India

energy conversion systems based on biomass are particularly interesting because biomass utilization effectively closes the carbon cycle besides achieving selfsustainability. Biomass is particularly useful for highly populated and agriculture dependent economic nations like China and India. A compact and cost effective downdrafl gasifcation system was developed. The present paper describes an experimental investigation on a biomass based gasifier engine system with a capacity of 35 kVA for power generation application. The problem of cooling and cleaning the hot and dirty gas from the gasifier has been satisfactorily solved by the effective cooling and filtration system. The gasifier developed is observed to be operation friendly. The quality of gas was evaluated in terms of its composition, conversion efficiency and total particulate matter. The maximum output of the power plant was obtained at the combustion zone temperature of 850~C. The experimental investigations showed that the percen- tage reduction in total particulate matter is 89.32%. The conversion efficiency of the biomass gasifier is found to be dependent on the operation conditions and fuel properties of the gasifier. The optimum value of equivalence ratio was observed to be 0.3134 for achieving the maximum gas conversion efficiency of the present gasifier configuration.

关键词： biomass gasification producer gas equivalence ratio total particulate matter conversion efficiency of gasifier

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