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黑长臂猿（Hy lobates concolor）对人类和非人类捕食者的回避行为

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人类学学报 1994年第2期13卷 181-188页

作者：蒋学龙马世来王应祥 L.k.Sheeran F.e.Poirier 中国科学院昆明动物研究所美国俄亥俄州立大学人类学系

捕食和避免捕食在动物生存和进化过程中起着重要作用．本文报道了我们自１９９０年３月至．１９９２年元月观察黑长臂猿（Ｈｙｌｏｂａｔｅｓｃｏｎｃｏｌｏｒ）对人类和非人类捕食者的一系列反映．在遇到人类（观察者）后，据离观察者... 详细信息

捕食和避免捕食在动物生存和进化过程中起着重要作用．本文报道了我们自１９９０年３月至．１９９２年元月观察黑长臂猿（Ｈｙｌｏｂａｔｅｓｃｏｎｃｏｌｏｒ）对人类和非人类捕食者的一系列反映．在遇到人类（观察者）后，据离观察者的远近和受惊程度不同，它们表现出５种回避方式．而在遇到非人类捕食者时，成年雌雄性一起将捕食者引开，以保护其后代个体免遭捕食．文中还对这些不同的行为方式进行了讨论．成年雄性是群体的主要保护者，成年雌性在群体保护中也起到重要的作用，不同个体的邀免捕食行为又有所不同，特别是幼体．

关键词：黑长臂猿人类捕食者回避行为

Novel LIPA mutations in Mexican siblings with lysosomal acid lipase deficiency

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World Journal of Gastroenterology 2015年第3期21卷 1001-1008页

作者： Yuritzi Santillán-Hernández enory Almanza-Miranda Winnie W Xin kendrick Goss Aurea Vera-Loaiza maría T Gorráez-de la Mora Raul e Pina-Aguilar Medical Genetics Department Centro Médico Nacional "20 de Noviembre"ISSSTEMéxico City 03100México Pediatric Gastroenterology Department Centro Médico Nacional "20 de Noviembre"ISSSTEMéxico City 03229México Neurogenetics DNA Diagnostic Laboratory Massachusetts General HospitalBostonMA 02114United States Pathology Department Centro Médico Nacional "20 de Noviembre"ISSSTEMéxico City 03229México Medical Genomics Division Centro Médico Nacional "20 de Noviembre"ISSSTEMéxico City 03100México

Lysosomal acid lipase(LAL) deficiency is an underrecognized lysosomal disease caused by deficient enzymatic activity of *** this report we describe two affected female Mexican siblings with early hepatic *** two months of age,the first sibling presented with alternating episodes of diarrhea and constipation,and later with hepatomegaly,elevated transaminases,high levels of total and low-density lipoprotein cholesterol,and low levels of highdensity *** hypertension and grade 2 esophageal varices were detected at four years of *** second sibling presented with hepatomegaly,elevated transaminases and mildly elevated lowdensity lipoprotein and low high-density lipoprotein at six months of *** activity was deficient in both *** of LIPA revealed two previously unreported heterozygous mutations in exon 4:c.253C>A and c.294C>*** cases highlight the clinical continuum between the so-called Wolman disease and cholesteryl ester storage disease,and underscore that LAL deficiency represents a single disease with a degree of clinical heterogeneity.

关键词： Cholesteryl ester storage disease Liver fibrosis Dyslipidemia Liver steatosis Wolman disease

Carbon pool dynamics after variable retention harvesting in Nothofagus pumilio forests of Tierra del Fuego

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ecological Processes 2023年第1期12卷 64-82页

作者： Jimena e.Chaves marie-Claire Aravena Acuña Julián Rodríguez-Souilla Juan M.Cellini Nolan J.Rappa maría V.Lencinas Pablo L.Peri Guillermo J.martínez Pastur Centro Austral de Investigaciones Científicas(CADIC) Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Houssay 200(9410)UshuaiaTierra del FuegoArgentina Laboratorio de Investigaciones en Maderas(LIMAD) Universidad Nacional de la Plata(UNLP)Diagonal 113469(1900)La PlataBuenos AiresArgentina Nature Conservation&Landscape ecology University of FreiburgTennenbacherstrasse 479106 FreiburgGermany Instituto Nacional de Tecnología Agropecuaria(INTA) Universidad Nacional de la Patagonia Austral(UNPA)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Cc 332(9400)Río GallegosSanta CruzArgentina

Background It is necessary to determine the implications for managing forest stands using variable retention harvesting for maintaining carbon and for calculating the effects of different harvesting practices on above-and below-ground carbon balance in forest *** this context,forest carbon management has gained more attention among managers and policy-makers during recent *** aim of this study was to determine carbon pool dynamics in different forest ecosystem components after variable retention harvesting(VRH)to characterize the ecological stability and quantify the recovery rate through the years-after-harvesting(YAH).Methods Carbon pool compartmentalization of 14 different components was determined in 60 harvested and primary unmanaged forests during the first 18 YAH in Tierra del Fuego(Argentina).We compared them using uni-and multi-variate methods,relativizing the outputs with primary unmanaged *** We determined the effectiveness to retain carbon components in post-harvested stands under different retention strategies(aggregated ***).The balance among carbon pool components changed between managed and unmanaged stands across the YAH,and was directly related to the impact *** retention improved the ecological stability of the harvested areas,where the below-ground components were more stable than the above-ground *** recovery rate was directly related to the post-harvesting natural dynamics of the *** studied period was not enough to fully recover the C levels of primary unmanaged for-ests,but VRH showed advantages to increase the C pools in the managed *** Promoting VRH can improve sustainable forestry at the landscape level and in the long term,generating positive synergies with biodiversity and the provision of ecosystem *** study provides important new insights into forest carbon management,in particular to setting standards in carbon projects and sets the ground

关键词： Carbon reservoir Temperate forest ecological stability Recovery rate Forest carbon management

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effect of arsenic on tolerance mechanisms of two plant growth-promoting bacteria used as biological inoculants

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Journal of environmental Sciences 2015年第7期27卷 203-210页

作者： Ana L.Armendariz Melina A.Talano Ana L.Wevar Oller maría I.Medina elizabeth Agostini Departamento de Biología Molecular FCEFQy N Universidad Nacional de Río Cuarto

Bacterial ability to colonize the rhizosphere of plants in arsenic（As） contaminated soils is highly important for symbiotic and free-living plant growth-promoting rhizobacteria（PGPR）used as inoculants, since they can contribute to enhance plant As tolerance and limit metalloid uptake by plants. The aim of this work was to study the effect of As on growth,exopolysaccharide（ePS） production, biofilm formation and motility of two strains used as soybean inoculants, Bradyrhizobium japonicum e109 and Azospirillum brasilense Az39. The metabolism of arsenate（As（V）） and arsenite（As（III）） and their removal and/or possible accumulation were also evaluated. The behavior of both bacteria under As treatment was compared and discussed in relation to their potential for colonizing plant rhizosphere with high content of the metalloid. B. japonicum e109 growth was reduced with As（III）concentration from 10 μM while A. brasilense Az39 showed a reduction of growth with As（III） from 500 μM. ePS and biofilm production increased significantly under 25 μM As（III）for both strains. Moreover, this was more notorious for Azospirillum under 500 μM As（III）,where motility was seriously affected. Both bacterial strains showed a similar ability to reduce As（V）. However, Azospirillum was able to oxidize more As（III）（around 53%） than Bradyrhizobium（17%）. In addition, both strains accumulated As in cell biomass. The behavior of Azospirillum under As treatments suggests that this strain would be able to colonize efficiently As contaminated soils. In this way, inoculation with A. brasilense Az39 would positively contribute to promoting growth of different plant species under As treatment.

关键词： Accumulation Arsenic Biofilm Colonization exopolysaccharides Plant growth-promoting rhizobacteria

Production and Sensory evaluation of Novel Cheeses Made with Prebiotic Substances:Inulin and Oligofructose

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Food and Nutrition Sciences 2015年第16期6卷 1489-1495页

作者： Laura M.Machuca Yamila e.Rodriguez Daniela e.Guastavino Meneguini maría e.Bruzzo maría F.Acuna Ojeda marcelo C.Murguía Institute of Scientific Research(IDIC) Faculty of Engineering and TechnologyUniversity of the Cuenca del Plata(UCP)CorrientesArgentina Laboratory of Applied Chemistry Faculty of Biochemistry and Biological SciencesNational University of the Litoral(UNL)Santa FeArgentina

In recent years, the processing and consumption of functional foods worldwide have greatly increased. These foods benefit the body functions which improve consumers’ health and also reduce the risk factors that cause the onset of disease. Furthermore, prebiotic substances favor the multiplication of beneficial intestinal bacteria rather than harmful ones. The purpose of this study was to conduct the sensory evaluation of two functional cheeses containing inulin and oligofructose as a distinctive ingredient, including testing a cheese made with conventional ingredients, called control cheese. Affective type tests, which measured the degree of liking or disliking, were conducted using a verbal 7-point hedonic scale. According to the inclusion and exclusion criteria, 57 untrained judges were selected. This study is a quantitative, analytic and experimental-cross design. Statistical analysis of the data was performed by ANOVA with repeated measures. The results show a similar average degree of liking for the three cheeses, above 5 on the scale or “like”. By analyzing the critical level and the result of the Mauchly’s sphericity test, it is concluded that there is no statistically significant difference in the degree of liking for the three cheeses. Therefore, the addition of prebiotics to artisanal cheeses achieves to satisfy consumers and provide them benefits superior to those provided by traditional foods.

关键词： Cheese Inulin Oligofructose Functional Foods

Forage offering and seasonal intake comparisons to evaluate european rabbit threat in Nothofagus forests of southern Patagonia

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ecological Processes 2022年第1期11卷 604-617页

作者： Alejandro Huertas Herrera Mónica Toro‑Manríquez Laura Borrelli maría Vanessa Lencinas Guillermo martínez Pastur Centro de Investigación en ecosistemas de la Patagonia(CIeP) Camino Baguales s/n Km 4CoyhaiqueChile Ulterarius Consultores Ambientales y Científicos Ltda. Ignacio Serrano 420CoyhaiqueChile Instituto Nacional de Tecnología Agropecuaria(INTA) EEA BarilocheModesta Victoria 44508400 San Carlos de BarilocheRío NegroArgentina Laboratorio de Recursos Agroforestales Centro Austral de Investigaciones Científicas(CADIC)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Houssay 2009410 UshuaiaTierra del FuegoArgentina.

Background:The european rabbit(Oryctolagus cuniculus L.1758)was introduced into different regions of the world,generating significant trade‑offs that critically impacted native ***,we evaluate the rabbit’s forage intakes in three vegetation types(forests,shrublands,and grasslands)along the four seasons in a temperate forest landscape in Southern Patagonia and discuss the potential threats over native *** formulated the following questions:(i)what is the forage offer at each vegetation type?(ii)what is the rabbit’s forage intake and how it varied across the seasons along the year?and(iii)which vegetation types and plant life forms were more used according to the rabbit’s forage intakes?Methods:We censused understory vegetation to characterize the forage offer at each vegetation type and determined seasonal dietary intakes using microhistological analysis of *** plant species identified in the field were grouped according to life form classes(tree regeneration,shrubs,forbs,graminoids,orchids,ferns,bryophytes,and hemiparasites).Data were analysed through uni‑and multi‑variate analyses,determining relationships between forage offer and the rabbit’s forage ***:Forage intakes revealed changes in plant life form consumption across vegetation types,where intake pressure was considerably different for tree regeneration(p=0.001),graminoids(p=0.001),and hemiparasites(p=0.001).Besides,significant changes in consumption among seasons were detected for shrubs(p=0.001),ferns(p=0.030),and hemiparasites(p=0.002).Although many species play an important role in the rabbit’s forage intake networks(e.g.,Chiliotrichum diffusum,Holcus lanatus),the strongest intake linkages were found in exotic grasses(e.g.,Poa pratensis and Festuca sp.),native hemiparasites(e.g.,Misodendrum sp.),native shrubs(e.g.,empetrum rubrum),and native trees(e.g.,Nothofagus sp.).The summer and autumn seasons presented higher intake compared to the winter and spring seasons.F

关键词： Forest ecology Oryctolagus cuniculus Plant-animal interaction Vegetation type Herbivory Habitat use

Intestinal anti-inflammatory effect of a plant sterol food supplement in experimental murine colitis and cell co-culture models

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Food Science and Human Wellness 2024年

作者： Mussa Makran Antonio Cilla Rosa maría Giner maría Carmen Recio Luisa Tesoriere Alessandro Attanzio Guadalupe Garcia-Llatas Nutrition and Food Science Area， Faculty of Pharmacy and Food Sciences， University of Valencia.Av.Vicente Andrés estellés s/n Department of Pharmacology， Faculty of Pharmacy and Food Sciences， University of Valencia.Av.Vicente Andrés estellés s/n Department of Biological， Chemical and Pharmaceutical Sciences and Technologies， University of Palermo

The potential of a plant sterol food supplement （PS-FS） in addressing intestinal inflammation in vivo and in vitro was evaluated. As in vivo model， C57BL/6J mice were exposed to 1.5% dextran sulfate sodium in three 5-day periods， with 10-day rest intervals in between， daily reciving PS-FS （35 mg PS/kg）. The in vitro approach involved a bi-cameral system with 8-day-differentiated Caco-2 （apical） and RAW264.7 cells （basolateral）. The bioaccessible fraction of PS-FS， obtained after INFOGeST 2.0 simulated gastrointestinal digestion， was added to the apical part （90 min）， followed by stimulation with lipopolysaccharide （1 μg/mL， 24 h）. PS-FS alleviated rectal bleeding and rebalanced pro- (tumor necrosis factor α， interleukin （IL）-6， and IL-8) and anti-inflammatory cytokines （IL-10）. Additionally， PS-FS ameliorated histopathological damage and enhancing occludin expression. A reduction in oxidative stress was evidenced by decreased myeloperoxidase activity and reactive oxygen species production. The anti-inflammatory mechanism included suppressing cyclooxygenase 2 expression， reducing prostaglandin e2production， and inhibiting the phosphorylation and nuclear translocation of the nuclear factor κB p65 subunit. This study reveals the potential of PS-FS as a therapeutic intervention for colitis. The alignment between in vivo and in vitro outcomes substantiates the appropriateness of the co-culture model to evaluate the anti-inflammatory activity of foods.

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Oxidation of glycerol with H_2O_2 on Pb-promoted Pd/γ-Al_2O_3 catalysts

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Chinese Journal of Catalysis 2016年第11期37卷 1982-1990页

作者： maría L.Faroppa Juan J.Musci maría e.Chiosso Claudia G.Caggiano Hernán P.Bideberripe José L.García Fierro Guillermo J.Siri Mónica L.Casella 布宜诺斯艾利斯西北国立大学 CIBA(CIT UNNOBACONICET) 拉普拉塔国立大学科学学院 CINDECA(CCT La Plata-CONICETUNLP) 拉普拉塔国立大学工程学院PIDCAT 西班牙国家研究委员会(CSIC)催化与石油化学研究所

A series of bimetallic Pd-Pb catalysts with a constant Pd content of 1 wt%and Pb/Pd atomic ratio from 0 to 1.6 supported on γ-Al2O3 were prepared and used for glycerol oxidation with H2O2 as the oxidizing agent at atmospheric pressure,45℃ and pH =*** morphology and dispersion of the catalysts were characterized by scanning electron microscopy-energy dispersive X-ray spectroscopy（SeM-eDX） and transmission electron microscopy（TeM）.The presence of an alloy phase in the bimetallic catalyst was detected by X-ray photoelectron spectroscopy（XPS）.Glycerol conversion obtained with the monometallic Pd catalyst was 19%,which was increased to 100%with the addition of *** four bimetallic PdPb catalysts were able to oxidize glycerol to dihydroxyacetone（DIHA） and the selectivity to DIHA reached 59%,58%,34%and 25%for PdPb0.25,PdPb0.50,PdPb1.00 and PdPbl.60 catalysts,respectively.

关键词： Palladium Bimetallic palladium-lead catalyst Hydrogen peroxide Glycerol oxidation Glyceric acid Glycolic acid

Hepatobiliary manifestations in inflammatory bowel disease: The gut,the drugs and the liver

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World Journal of Gastroenterology 2013年第42期19卷 7327-7340页

作者： maría Rojas-Feria Manuel Castro emilio Suárez Javier Ampuero Manuel Romero-Gómez Unit for Medical and Surgical Management of Digestive Diseases and CIBeRehd Valme University HospitalUniversity of SevilleE-41014 SevillaSpain

Abnormal liver biochemical tests are present in up to30%of patients with inflammatory bowel disease(IBD),and therefore become a diagnostic *** and biliary tract diseases are common extraintestinal manifestations for both Crohn’s disease and ulcerative colitis(UC),and typically do not correlate with intestinal *** sclerosing cholangitis(PSC)is the most common hepatobiliary manifestation of IBD,and is more prevalent in *** 5%of patients with UC develop PSC,with the prevalence reaching up to 90%.Cholangiocarcinoma and colon cancer risks are increased in these *** common disorders include autoimmune hepatitis/PSC overlap syndrome,IgG4-associated cholangiopathy,primary biliary cirrhosis,hepatic amyloidosis,granulomatous hepatitis,cholelithiasis,portal vein thrombosis,liver abscess,and non-alcoholic fatty liver *** B reactivation during immunosuppressive therapy is a major concern,with screening and vaccination being recommended in serologically negative cases for patients with *** prophylaxis with entecavir or tenofovir for 6to 12 mo after the end of immunosuppressive therapy is mandatory in patients showing as hepatitis B surface antigen(HBsAg)positive,independently from viral *** negative and anti-HBc positive patients,with or without anti-HBs,should be closely monitored,measuring alanine aminotransferase and hepatitis B virus DNA within 12 mo after the end of therapy,and should be treated if the viral load *** the other hand,immunosuppressive therapy does not seem to promote reactivation of hepatitis C,and hepatitis C antiviral treatment does not influence IBD natural history *** of the drugs used for IBD treatment may induce hepatotoxicity,although the incidence of serious adverse events is *** in liver biochemical tests associated with aminosalicylates are uncommon and are usually not clinically *** hepatotoxicity has been describ

关键词： Inflammatory bowel disease Hepatobiliary disorders extraintestinal manifestations Primary sclerosing cholangitis Drug-induced liver injury Hepatotoxicity Hepatitis B Hepatitis C