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Biochar 2021年第3期3卷 349-365页

作者： Megan de.jager Luise Giani Carl Von Ossietzky Universität Institut Für Biologie Und UmweltwissenschaftenOldenburgGermany

The hydrothermal carbonization(HTC)of biogas digestate alters the raw materials inherent characteristics to produce a carbon(C)-rich hydrochar(HC),with an improved suitability for soil *** studies report conflicting impacts of various HC application rates on soil properties and plant *** this study,the influence of HC application rate on soil improvement and plant growth aspects was investigated in three diverse soils(Chernozem,Podzol,and Gleysol).Pot trials were conducted in which all soils were amended with 5,10,20 and 30%(w/w)HC in quintuplicate,with two controls of pure soil(with and without plants,respectively)also *** to potting,soil samples were collected from all HC-amended soils and controls and analyzed for soil pH,plant available nutrients(PO4-P and K),and microbial activity using standard laboratory and statistical *** after potting,a 6-week seed germination experiment using Chinese cabbage was conducted to determine germination success,followed by a plant growth experiment of equal duration and plant species to determine biomass *** the end of the study(after a total plant growth period of 12 weeks),each pot was sampled and comparatively analyzed for the same soil properties as at the beginning of the *** pH shifted toward the pH of the HC(6.6)in all soils over the course of the study,but was most expressed in the 20%and 30%application rates,confirming the well-documented liming effect of *** addition of HC increased the PO4-P and K contents,particularly with 20%and 30%HC *** results are proposedly due to the large labile C fraction of the HC,which is easily degradable by *** rapid decomposition of this C fraction prompted the quick release of the HCs inherently high PO4-P and K content into the soil,and in turn,further stimulated microbial activity,until this fraction was essentially *** addition did not inhibit seed germination at any rate,presumabl

关键词： Biogas digestate Hydrochar application rate Soil improvement Nutrient availability Microbial activity

NeCAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael K.e.Schafer Sudena Wang Michael J.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding proteins 1–3(NeCAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one eF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NeCAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NeCAB2 interacts with predominantly striatal G-protein-coupled receptors, while NeCAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NeCAB proteins exhibit distinct subcellular localizations: NeCAB1 is found in the nucleus and cytosol, NeCAB2 resides in endosomes and the plasma membrane, and NeCAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NeCAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NeCAB proteins by controlling the availability of protein–protein interaction domains situated between the eF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

Recent Advancements in the Optimization Capacity Configuration and Coordination Operation Strategy of Wind-Solar Hybrid Storage System

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energy engineering 2025年第1期122卷 285-306页

作者： Hongliang Hao Caifeng Wen Feifei Xue HaoQiu Ning Yang Yuwen Zhang Chaoyu Wang edwin e.Nyakilla Department of New energy Storage Peking University Ordos Research Institute of EnergyOrdos017010China School of energy and Power engineering Inner Mongolia University of TechnologyHohhot010080China Key Laboratory of Wind energy and Solar energy Utilization Technology Inner Mongolia University of TechnologyHohhot010051China

Present of wind power is sporadically and cannot be utilized as the only fundamental load of energy *** paper proposes a wind-solar hybrid energy storage system(HeSS)to ensure a stable supply grid for a longer period.A multi-objective genetic algorithm(MOGA)and state of charge(SOC)region division for the batteries are introduced to solve the objective function and configuration of the system capacity,***/Simulink was used for simulation *** optimization results show that for a 0.5 MW wind power and 0.5 MW photovoltaic system,with a combination of a 300 Ah lithium battery,a 200 Ah lead-acid battery,and a water storage tank,the proposed strategy reduces the system construction cost by approximately 18,000 ***,the cycle count of the electrochemical energy storage systemincreases from4515 to 4660,while the depth of discharge decreases from 55.37%to 53.65%,achieving shallow charging and discharging,thereby extending battery life and reducing grid voltage fluctuations *** proposed strategy is a guide for stabilizing the grid connection of wind and solar power generation,capability allocation,and energy management of energy conservation systems.

关键词： electric-thermal hybrid storage modal decomposition multi-objective genetic algorithm capacity optimization allocation operation strategy

The influence of hydrochar from biogas digestate on soil improvement and plant growth aspects

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Biochar 2020年第2期2卷 177-194页

作者： Megan de.jager Michael Rohrdanz Luise Giani Carl Von Ossietzky Universitat Institut für Biologie und UmweltwissenschaftenOldenburgGermany

Hydrochar(HC),produced by hydrothermal carbonization,offers technical advantages over biochar(BC)produced by pyrolysis,and is suitable for soil amelioration,carbon sequestration,and enhanced plant *** grain size has been shown to influence nutrient retention,microbial colonization and aggregate formation;however,similar research for HC is *** trials were conducted to investigate the influence of HC grain size[coarse(6.3-2 mm),medium(2-0.63 mm)and fine(ed from biogas digestate,for soil improvement in three soils:loamy Chernozem,sandy Podzol,and clayey Gleysol,at a 5%HC application rate(w/w).All soils including two controls(with and without plants)were analysed for water holding capacity(WHC),cation exchange capacity(CeC),wet aggregate stability,pH,plant available nutrients(PO_(4)-P,K and N_(min))and germination and biomass success using standard laboratory and statistical *** pH showed a compensatory shift toward the HC pH(7.2)in all soils over the course of the *** example,the pH of the medium grained HC treatment for the Chernozem decreased from 7.9 to 7.2 and increased in the Podzol and Gleysol from 5.9 to 6.1 and 4.9 to 5.5,*** nutrient-rich HC(2034±38.3 mg kg^(−1) PO_(4)-P and 2612.5±268.7 mg kg^(−1) K content)provided only a short-term supply of nutrients,due to the relatively easily mineralized fraction of HC,which allowed for quick nutrient *** pH and PO_(4)-P effects were most pronounced in the fine grained HC treatments,with a~87%,~308%and~2500%increase in PO_(4)-P content in the Chernozem,Podzol and Gleysol,respectively,compared to the controls at the beginning of the *** same trend was observed for the K and NH_(4)^(+)content in the fine and medium grained HC treatments in all *** seed germination inhibition of Chinese cabbage was observed,with average germina-tion rates>50%in all *** effect on NO_(3)^(−)content was indeterminable,while there was little to no effect on biom

关键词： Hydrochar Soil improvement Grain size Plant available nutrients

Novel fabrication of soft microactuators with morphological computing using soft lithography

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Microsystems & Nanoengineering 2019年第1期5卷 217-226页

作者： Manav Tyagi Jingle Pan edwin W.H.jager Sensor and Actuator Systems Department of PhysicsChemistryand Biology(IFM)Linköping UniversityLinköping 58183Sweden

A simple and cost-effective method for the patterning and fabrication of soft polymer microactuators integrated with morphological computation is *** microactuators combine conducting polymers to provide the actuation,with spatially designed structures for a morphologically controlled,user-defined *** lithography is employed to pattern and fabricate polydimethylsiloxane layers with geometrical pattern,for use as a construction element in the *** microactuators could obtain multiple bending motions from a single fabrication process depending on the morphological pattern defined in the final *** of fabricating via conventional photolithography route,which involves multiple steps with different chromium photomasks,this new method uses only one single design template to produce geometrically patterned layers,which are then specifically cut to obtain multiple device *** desired design of the actuator is decided in the final step of *** resulting microactuators generate motions such as a spiral,screw,and tube,using a single design template.

关键词： lithography template pattern

Merging bound states in the continuum in an open acoustic resonator

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 124-131页

作者： Lujun Huang Bin Jia Artem S.Pilipchuk Sibo Huang Chen Shen Almas F.Sadreev Yong Li Andrey e.Miroshnichenko School of Physics and electronic Sciences East China Normal University Institute of Acoustics Tongji University L.V.Kirensky Institute of Physics Department of Mechanical engineering Rowan University School of engineering and Technology University of New South Wales at Canberra

Bound states in the continuum （BICs） are perfectly localized resonances despite embedding in the continuum ***,an isolated BIC is very sensitive to the structure ***,we report merging acoustic BICs in a single open resonator,robust against the structure *** find that both symmetry-protected BIC and Friedrich-Wintgen BIC are sustained in a single coupled waveguide-resonator *** varying the height and length of the resonator,these two BICs move toward each other and merge into a single one at a critical *** to an individual BIC,the merged BIC is robust against fabrication error because its Q-factor is proportional to ΔL-4,whereΔL embodies the structure *** essence of this extraordinary phenomenon is perfectly explained by the two-and three-level approximations of the effective nonHermitian ***,we present direct experimental demonstrations of the moving and merging of BICs in a coupled 3D waveguide-resonator,which are evidenced by the vanishing of the linewidth of Fano resonance in the transmission *** results may find exciting applications in designing high-quality acoustic sources,sensors and filters.

关键词： acoustic resonances bound state in the continuum high-Q resonances

Role of ethnicity in social anxiety disorder: A cross-sectional survey among health science students

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World Journal of Clinical Cases 2014年第7期2卷 265-271页

作者： Philip De.jager Sharain Suliman Soraya Seedat Vrije Universiteit Faculty of Health Sciences1055 VB AmsterdamThe Netherlands Department of Psychiatry Faculty of Medicine and Health SciencesStellenbosch UniversityTygerberg 7505South Africa

AIM: To investigate the influence of ethnicity in social anxiety disorder(SAD), and the relationship with symptom severity, depression and substance use or abuse, in health sciences' ***: This was a cross-sectional survey of 112 1st, 2nd and 3rd year students from the Faculty of Medicine and Health Sciences at Stellenbosch University, Cape Town, South Africa. The self-reported Social Anxiety Spectrum questionnaire was used to assess for SAD. The Social Phobia Inventory(SPIN) was adapted to a version called the e-SPIN(ethnic-SPIN) in order to evaluate the effects of ethnicity. Two sub-questions per stem question were included to assess whether SAD symptoms in social interactions were ethnicity dependent. Substance use was assessed with the Alcohol UseDisorders Identification Test and Drug Use Disorders Identification Test, and depression with the Centre for epidemiological Studies Depression ***: Of 112 students who completed the e-SPIN questionnaire, 54.4%(n = 61) met criteria for SAD, with significantly more females than males meeting criteria. ethnicity had a significant effect on SAD symptomatology, but there was no effect of ethnicity on the rates of drug and alcohol abuse in students with and without SAD. Overall significantly more students with SAD met criteria for depression compared with students without the disorder. CONCLUSION: Among university students, SAD is prevalent regardless of whether interactions are with individuals of the same or different ethnic group. However, ethnicity may be an important determinant of social anxiety for some ethnic groups. SAD was significantly associated with major depression but not significantly associated with drug or alcohol abuse.

关键词： Social anxiety Social phobia ethnicity Students South Africa

Hybrid Additive Manufacturing of Forming Tools

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Automotive Innovation 2023年第3期6卷 311-323页

作者： Hamed Dardaei Joghan Ramona Holker‑jager Anna Komodromos A.erman Tekkaya Institute of Forming Technology and Lightweight Components(IUL) TU Dortmund UniversityBaroper Stra.e 30344227 DortmundGermany

Additive manufacturing(AM)is widely used in the automotive industry and has been expanded to include aerospace,marine,and *** flexibility and the possibility of manufacturing complex parts in AM motivate the integration of additive manu-facturing with classical forming technologies,which can improve tooling concepts and reduce *** study presents three applications of this ***,the possibility of successful utilization of selective laser melting for manufacturing extrusion tools with complex cooling channels and paths for thermocouples is reported,leading to significantly reduced inner die temperatures during the extrusion ***,sheet lamination is integrated with laser metal deposition(LMD)to manufacture deep-drawing *** results are achieved in reducing the stair step effect,which is the main challenge in sheet lamination,by LMD and following post-processing such as milling,ball burnishing,and laser *** new manufacturing route shows that LMD can economically and efficiently reduce the stair step effect and omit the hardening step from the conventional manufacturing process ***,LMD is used to manufacture a hot stamping punch with improved surface roughness by ball burnishing and near-surface complex cooling *** experimental results show that the manufactured punch has lower temperatures during hot stamping compared with the conventionally manufactured *** study shows the successful integration of AM processes with classical forming processes.

关键词： Additive manufacturing Laser metal deposition Selective laser melting Rapid tooling Forming tool Layer laminated manufacturing

enhancing perianal disease management with integrated physical and psychological approaches

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World Journal of Clinical Cases 2025年第2期13卷 59-63页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal *** study sheds light on how illness perception,anxiety,and depression significantly influence recovery *** et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor *** article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for *** study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.

关键词： Perianal disease Post-operative recovery Anxiety Depression Pain management emotional well-being Multidisciplinary approach