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Possible ameliorative effect of breastfeeding and the uptake of human colostrum against coeliac disease in autistic rats

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World Journal of Gastroenterology 2013年第21期19卷 3281-3290页

作者： Manar e Selim Laila y Al-Ayadhi Zoology Department Faculty of ScienceKing Saud UniversityAutism Research and Treatment CentreRiyadh 11459 Saudi Arabia Zoology Department Faculty of ScienceAin Shams UniversityCairo 11511Egypt Physiology Department Faculty of MedicineKing Saud UniversityAutism Research and Treatment CentreRiyadh 11459Saudi Arabia

AIM: To examine the possible ameliorative effect of breastfeeding and the uptake of human colostrum against coeliac disease in autistic rats. MeTHODS: Female rats were fed a standard diet and received a single intraperitoneal injection of 600 mg/kg sodium valproate on day 12.5 after conception. In study 1, neonatal rats were randomly subjected to blood tests to investigate autism. In study 2, the 1st group was fed by the mother after an injection of interferon-γ (IFN-γ) and administration of gliadin. The pups in the 2nd group were prevented from accessing maternal milk, injected IFN-γ, administered gliadin, and hand-fed human colostrum. The normal littermates fed by the table mothers were injected with physiological saline and served as normal controls in this ***: The protein concentration was higher in group 2 than in group 1 in the duodenum (161.6 ± 9 and 135.4 ± 7 mg/g of tissue, respectively, P ease (P y weight was detected in human colostrum-treated pups on post natal day (PND) 7 and 21 vs suckling pups in group 1. A delay in eye opening was noticed in the treated rats in group 1 on PND 13 compared with the control group and group 2. Administration of a single intraperitoneal injection of 600 mg/kg sodium valproate on day 12.5 after conception resulted in significantly reduced calcium and vitamin D levels in study 1 compared with the control groups (P ever, human colostrum uptake inhibited increases in the level of transglutaminase antibody in autistic pups with coeliac disease. CONCLUSION: The effects of early-life nutrition and human colostrum on the functional maturation of the duodenal villi in autistic rats with coeliac disease that might limit or prevent the coeliac risk with autism.

关键词： Autism Breastfeeding Coeliac disease Human colostrum

Moth-eye Structured Polydimethylsiloxane Films for High-efficiency Perovskite Solar Cells

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Nano-Micro Letters 2019年第3期11卷 271-280页

作者： Mincheol Kim Segeun Jang Jiwoo choi Seong Min Kang Mansoo choi Global Frontier Center for Multiscale energy Systems Seoul National UniversitySeoul151.744Republic of Korea Department of Mechanical and Aerospace engineering Seoul National UniversitySeoul151.744Republic of Korea Department of Mechanical engineering Hanbat National UniversityDaejeon34158Republic of Korea Department of Mechanical engineering Chungnam National UniversityDaejeon34134Republic of Korea

Large-area polydimethylsiloxane(PDMS)films with variably sized moth-eye structures were fabricated to improve the efficiency of perovskite solar *** approach that incorporated photolithography,bilayer PDMS deposition and replication was used in the fabrication *** simply attaching the moth-eye PDMS films to the transparent substrates of perovskite solar cells,the optical properties of the devices could be tuned by changing the size of the moth-eye *** device with 300-nm moth-eye PDMS films greatly enhanced power conversion efficiency of ~21 % due to the antireflective effect of the moth-eye ***,beautiful coloration was observed on the 1000-nm moth-eye PDMS films through optical interference caused by the diffraction grating *** results imply that moth-eye PDMS films can greatly enhance the efficiency of perovskite solar cells and building-integrated photovoltaics.

关键词： Polydimethylsiloxane films Moth-eye Photolithography Perovskite solar cells Photovoltaic

Advanced Community Identification Model for Social Networks

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Computers, Materials & Continua 2021年第11期69卷 1687-1707页

作者： Farhan Amin Jin-Ghoo choi Gyu Sang choi Department of Computer engineering Gachon UniversityGyeonggi-do13120Korea Department of Information and Communication engineering Yeungnam UniversityGyeongsan38541Korea

Community detection in social networks is a hard problem because of the size,and the need of a deep understanding of network structure and *** several methods with significant effort in this direction have been devised,an outstanding open problem is the unknown number of communities,it is generally believed that the role of influential nodes that are surrounded by neighbors is very *** addition,the similarity among nodes inside the same cluster is greater than among nodes from other ***,the global and local methods of community detection have been getting more ***,in this study,we propose an advanced communitydetection model for social networks in order to identify network communities based on global and local *** proposed model initially detects the most influential nodes by using an eigen score then performs local expansion powered by label *** process is conducted with the same color till nodes reach maximum ***,the communities are formed,and a clear community graph is displayed to the *** proposed model is completely parameter-free,and therefore,no prior information is required,such as the number of communities,*** perform simulations and experiments using well-known synthetic and real network benchmarks,and compare them with well-known state-of-the-art *** results prove that our model is efficient in all aspects,because it quickly identifies communities in the ***,it can easily be used for friendship recommendations or in business recommendation systems.

关键词： Community detection social network analysis complex networks

Optimization of a High Speed Spinning Disk Spindle System for Minimum RRO,NRRO,and Lightweight by Using G.A.

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厦门大学学报(自然科学版) 2002年第S1期41卷 89-90页

作者： y H choi S T Kim K C yoon J M Kim y J Kang Dept.of Mechanical Design and Manufacturing Changwon National UniversityKyungnam 641-773Korea Dept.of Mechanical engineering Changwon National UniversityKyungnam 641-773Korea Senoir Research engineer R&D Cente FAGHANWHA Bearing Corp.Kyungnam 641-020Korea Graduate Student Dept.of Mechanical Design and ManufacturingChangwon National UniversityKyungnam 6412773Korea

Law level of RRO(Repeatable Run Out),NRRO(Non Repe at able Run Out),and lightweight construction are a major trend in the high-speed HDD(Hard Disk Drive)sytem to reduce track misregestration and to achieve high track density,which lead to succeed in the ***,it is not easy to r educe RRO,NRRO,and the weight of the spinning disk spindle system efficiently because lightweight construction and or bearing stiffness changes often yields a decrease in the static and dynamic stiffness of the system,and consequently hi gh vibrations may be generated as a ***,it is of importance to e valuate in advance the accurate dynamic behavior of the high speed spinning disk spindle system of a HDD *** study introduces an optimum design of the high speed spinning disk spindle system of a HDD for minimum RRO,NRRO,and lightweight construction using a gene tic *** spinning disk,hub,and bearing components of a HDD system ar e modelled as appropriate finite elements respectively and their equations of mo tion are derived to construct the system equations of the whole spinning disk sp indle system of the HDD *** RRO and NRRO responses of the spinning disk,due to exciting forces arised from ball bearing faults and rotating unbalance,are *** the design optimation,the hub thickness,the disk thickness,bearing positio ns(or bearing span)and bearing stiffness were set as design *** uni que objective function is obtained by multiplying an appropriate weighting facto r by multi-objective functions,such as RRO,NRRO,and the total weight of HDD the *** constraints are maximum RRO limit,maximum weight linit,and the critical speed limit of the HDD spindle *** show that the RRO,NRRO,and weight are reduced by 6%,66.7%and 28%r espectively compared with the initial design of the HDD ***,thi s present study can be used for an optimum design of the spinning disk spindle s ystem of a HDD for lightweight construction

关键词： design optimization genetic algorithm multiobjective optimization repeatable run out non repeatable run out

Influence of the wastewater composition on denitrification and biological P-removal in the S-DN-P process: (c) Dissolved and undissolved substrates

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Journal of environmental Sciences 2009年第8期21卷 1074-1079页

作者： Hee-Jeong choi Chul-Ho choi Seung-Mok Lee Diwakar Tiwari Department of environmental engineering Kwandong University Department of Chemistry School of Physical Sciences Mizoram University

The denitdfication and P-removal in the sorption-denitrification-P-removal （S-DN-P） process were carded out under various wastewater compositions. It is noted that P-removal largely depends on the wastewater composition as well to the quantity of the substrates present in wastewater fraction. Three different wastewater fractions are obtained as： raw wastewater, dissolved wastewater （obtained with filtration using 0.45 μm filter）, and undissolved wastewater （i.e., infiltrate obtained by above filtration）. The ratio of P-release/CODtotal-consumption clearly inferred that undissolved wastewater possess very low value i.e., 0.0008 followed by raw wastewater 0.008 and dissolved wastewater 0.03. When this ratio was nearby 0.01, enhanced P-removal was observed. Moreover, the ratio of P-uptake to NO3^--N decomposition for raw wastewater was two times for dissolved wastewater. Interestingly, it was observed that the P-removal and denitrification depend not only on the dissolved substrates but also the undissolved substrates present in the wastewater. The result of the P-removal obtained with this S-DN-P process did not show a big difference of 36%, 34% and 30%, respectively, for raw, dissolved and undissolved wastewater.

关键词： denitrification polyhydroxybutyrate sequencing batch biofilm reactor sorption denitrification P-removals

existence of T-solution for Degenerated Problem via Minty's Lemma

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Acta Mathematica Sinica,english Series 2008年第3期24卷 431-438页

作者： y.AKDIMe e.AZROUL M.RHOUDAF Département de Mathématiques et Informatique Facultédes Sciences Dhar-Mahraz B. P 1796 Atlas Fès Maroc

We study the existence result of solutions for the nonlinear degenerated elliptic problem of the form, -div（a（x, u,△↓u）） = F in Ω, where Ω is a bounded domain of R^N, N≥2, a ：Ω×R×R^N→R^N is a Carathéodory function satisfying the natural growth condition and the coercivity condition, but they verify only the large monotonicity. The second term F belongs to W^-1,p′（Ω, w^＊）. The existence result is proved by using the L^1-version of Minty＇s lemma.

关键词： weighted Sobolev spaces truncations L^1-version of Minty's lemma

epidural electrical stimulation for spinal cord injury

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Neural Regeneration Research 2021年第12期16卷 2367-2375页

作者： elliot H.choi Sandra Gattas Nolan J.Brown John D.Hong Joshua N.Limbo Alvin y.Chan Michael y.Oh Department of Pharmacology School of MedicineCase Western Reserve UniversityClevelandOHUSA Department of Ophthalmology Gavin Herbert Eye InstituteSchool of MedicineUniversity of CaliforniaIrvineCAUSA Department of Neurosurgery University of CaliforniaIrvineCAUSA

A long-standing goal of spinal cord injury research is to develop effective repair strategies,which can restore motor and sensory functions to near-normal *** advances in clinical management of spinal cord injury have significantly improved the prognosis,survival rate and quality of life in patients with spinal cord *** addition,a significant progress in basic science research has unraveled the underlying cellular and molecular events of spinal cord *** efforts enabled the development of pharmacologic agents,biomaterials and stem-cell based *** these efforts,there is still no standard care to regenerate axons or restore function of silent axons in the injured spinal *** challenges led to an increased focus on another therapeutic approach,namely *** multiple animal models of spinal cord injury,epidural electrical stimulation of the spinal cord has demonstrated a recovery of motor *** evidence regarding the efficacy of epidural electrical stimulation has further expanded the potential of epidural electrical stimulation for treating patients with spinal cord ***,most clinical studies were conducted on a very small number of patients with a wide range of spinal cord ***,subsequent studies are essential to evaluate the therapeutic potential of epidural electrical stimulation for spinal cord injury and to optimize stimulation ***,we discuss cellular and molecular events that continue to damage the injured spinal cord and impede neurological recovery following spinal cord *** also discuss and summarize the animal and human studies that evaluated epidural electrical stimulation in spinal cord injury.

关键词： central nervous system chondroitin sulfate proteoglycans epidural electrical stimulation glial scar gliosis neural activity neuromodulation oligodendrocyte spinal cord injury

An approach to dark energy problem through linear invariants

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Chinese Physics C 2011年第3期35卷 233-242页

作者： Jeong Ryeol choi Department of Radiologic Technology Daegu Health College Division of Semiconductor and Display engineering College of IT EngineeringKyungpook National University

The time evolution of vacuum energy density is investigated in the coherent states of inflationary universe using a linear invariant approach. The linear invariants we derived are represented in terms of annihilation operators. On account of the fact that the coherent state is an eigenstate of an annihilation operator, the wave function in the coherent state is easily evaluated by solving the eigenvalue equation of the linear invariants. The expectation value of the vacuum energy density is derived using this wave function. Fluctuations of the scalar field and its conjugate momentum are also investigated. Our theory based on the linear invariant shows that the vacuum energy density of the universe in a coherent state is decreased continuously with time due to nonconservative force acting on the coherent oscillations of the scalar field, which is provided by the expansion of the universe. In effect, our analysis reveals that the vacuum energy density decreases in proportion to t-β where β is 3/2 for radiation-dominated era and 2 for matter-dominated era. In the case where the duration term of radiation-dominated era is short enough to be negligible, the estimation of the relic vacuum energy density agrees well with the current observational data.

关键词： cosmological constant problem vacuum energy density coherent state linear invariant

Free vibration and transient response of double curved beams connected by intermediate straight beams

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Applied Mathematics and Mechanics(english edition) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-TALOOKOLAeI H.GHANDVAR e.JUMAeV S.KHATIR T.CUONG-Le School of Mechanical engineering Babol Noshirvani University of Technology Department of Mechanical engineering Faculty of Engineering New Uzbekistan University University of Business and Science Center for engineering Application and Technology Solutions Ho Chi Minh City Open University

This paper investigates the free vibration and transient response of interconnected structures including double curved beams and intermediate straight beams,which are all constructed from functionally graded porous(FGP) materials. The strain potential and kinetic energies of each beam along with the work done by the external force are calculated. Additionally, a higher-order beam element is introduced to derive stiffness and mass matrices, along with the force vector. The curved and straight beams are discretized, and their assembled stiffness, mass matrices, and force vectors, are *** conditions at the joints are used to derive the total matrices of the entire structure. Subsequently, the natural frequencies and transient response of the system are determined. The accuracy of the mathematical model and the self-developed computer program is validated through the comparison of the obtained results with those of the existing literature and commercial software ANSyS, demonstrating excellent ***, a comprehensive study is conducted to investigate the effects of various parameters on the free vibration and transient response of the considered structure.

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