检索结果-南通市图书馆

Highly selective and eco-friendly dihydroisoquinoline synthesis via Cu/Co synergistic catalysis in Cu NPs@MOFs catalyst under mild conditions

引用

Science China Chemistry 2024年第5期67卷 1561-1568页

作者： Peng-Fei Guo Ze-Long Liang Yue-e Jiao Hang Xu Bin Zhao Key Laboratory of Advanced energy Material Chemistry Renewable Energy Conversion and Storage CenterDepartment of ChemistryNankai UniversityTianjin 300071China

3,4-Dihydroisoquinoline(DHIQ)is an important precursor used in the production of drugs for treating cancer,HIV,Alzheimer's disease,*** studies on DHIQ synthesis show low catalytic selectivity due to the susceptible over-oxidation feedstock of1,2,3,4-tetrahydroisoquinoline(THIQ),which often requires alkali ***,it is desirable yet challenging to explore a highly selective and efficient oxydehydrogenation capacity for DHIQ synthesis under eco-friendly reaction ***,a novel framework 1 was synthesized,exhibiting 1D channels with the size of 4.6 A×9.6 A and high solvent/p H/thermal stability.A stable framework allows it to encapsulate Cu nanoparticles(NPs)to form Cu NPs@1-x(x=1,2,3,and 4)with varying loading amounts of Cu NPs at 2.0 wt%,3.0 wt%,4.0 wt%,and 6.0 wt%,*** NPs@1-3 could selectively catalyze the reaction from THIQ to DHIQ with a high selectivity of 98%and a recorded turnover frequency(TOF)of 22.1 h-1under eco-friendly mild *** corresponding catalytic activity can maintain at least five recyclings and can be further applied to gram-scale ***,the efficient preparation of DHIQ catalyzed by Cu NPs@1-3 could be realized even under air ***,the anticancer molecule precursor synthesis of 6,7-dimethoxy-3,4-dihydroisoquinoline was also selectively catalyzed by Cu NPs@*** investigations revealed that high catalytic performance can be attributed to the stable framework and the synergistic catalytic effect of the loaded Cu NPs and Co metal *** importantly,this work represents the first example of MOF catalysts for selectively thermo-catalytic DHIQ synthesis and demonstrates a simple approach to obtain efficient catalysts for selective oxydehydrogenation in the production of unsaturated compounds.

关键词： metal-organic frameworks Cu NPs@MOFs 3 4-dihydroisoquinoline selective oxydehydrogenation synergistic catalysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

miniSCIDOM: a scintillator-based tomograph for volumetric dose reconstruction of single laser-driven proton bunches

引用

High Power Laser Science and engineering 2024年第2期12卷 41-50页

作者： A.Corvino M.Reimold e.Beyreuther F.-e.Brack F.Kroll J.Pawelke J.D.Schilz M.Schneider U.Schramm M.e.P.Umlandt K.Zeil T.Ziegler J.Metzkes-Ng Helmholtz-Zentrum Dresden–Rossendorf DresdenGermany Technische Universität Dresden DresdenGermany OncoRay–National Center for Radiation Research in Oncology Faculty of Medicine and University Hospital Carl Gustav CarusTUD Dresden University of TechnologyHelmholtz-Zentrum Dresden–RossendorfDresdenGermany Current affiliation:Institut Curie UniversitéPSLCNRS UMR3347OrsayFrance Current affiliation:Universitätsklinikum Freiburg FreiburgGermany

Laser plasma accelerators(LPAs)enable the generation of intense and short proton bunches on a micrometre scale,thus offering new experimental capabilities to research fields such as ultra-high dose rate radiobiology or material *** spectrally broadband,laser-accelerated proton bunches allow for tailored volumetric dose deposition in a sample via single bunches to excite or probe specific sample *** rising number of such experiments indicates a need for diagnostics providing spatially resolved characterization of dose distributions with volumes of approximately 1 cm^(3) for single proton bunches to allow for fast online *** we present the scintillator-based miniSCIDOM detector for online single-bunch tomographic reconstruction of dose distributions in volumes of up to approximately 1 cm^(3).The detector achieves a spatial resolution below 500μm and a sensitivity of 100 *** detector performance is tested at a proton therapy cyclotron and an LPA proton *** experiments’primary focus is the characterization of the scintillator’s ionization quenching behaviour.

关键词： beam monitoring detectors laser-driven proton beams scintillator-based diagnostics ultra-high dose rate

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mortality rate after total knee arthroplasty or total hip arthroplasty in patients with a history of liver transplant

引用

World Journal of Orthopedics 2024年第4期15卷 310-311页

作者： e Carlos Rodriguez-Merchan Department of Orthopedic Surgery La Paz University Hospital-IdiPazMadrid 28046Spain

In this editorial I comment on the article by Ahmed et al published in a recent issue of the World J Orthop 2023;14:*** is well known that patients who have undergone a liver transplant(LT)may need to have a total hip arthroplasty(THA)or total knee arthroplasty(TKA)*** et al stated that the mortality rate in these patients was similar to the one of the general ***,there are three articles previously published that found higher mortality in LT patients who experienced THA/TKA than in the general population(individuals without LT).Therefore,in this editorial I would like to point out that there is controversy in the literature regarding whether LT patients undergoing THA/TKA have higher mortality than the general ***,future research should attempt to resolve this controversy.

关键词： Liver transplant Total knee arthroplasty Total hip arthroplasty Results Mortality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Non-canonical BRAF variants and rearrangements in hairy cell leukemia

引用

Oncology Research 2024年第9期32卷 1423-1427页

作者： STePHeN e.LANGABeeR Cancer Molecular Diagnostics St.James’s HospitalDublinD08 W9RTIreland

Hairy cell leukemia(HCL)is an uncommon mature B-cell malignancy characterized by a typical morphology,immunophenotype,and clinical *** vast majority of HCL patients harbor the canonical BRAF V600e mutation which has become a rationalized target of the subsequently deregulated RAS-RAF-MeK-MAPK signaling pathway in HCL patients who have relapsed or who are refractory to front-line ***,several HCL patients with a classical phenotype display non-canonical BRAF mutations or *** include sequence variants within alternative exons and an oncogenic fusion with the IGH *** must be taken in the molecular diagnostic work-up of patients with typical HCL but without the BRAF V600e to include investigation of these uncommon ***,functional characterization,and reporting of further such patients is likely to provide insights into the pathogenesis of HCL and enable rational selection of targeted inhibitors in such patients if required.

关键词： Hairy cell leukemia BRAF Molecular diagnostics Targeted therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Potential of Bamboo Species Guadua trinii and Guadua angustifolia for Nanocellulose Production

引用

Journal of Renewable Materials 2024年第9期12卷 1541-1555页

作者： Agatha e. R. Prado Gárate Fernando e. Felissia María Cristina Area Teresa Suirezs María evangelina Vallejos Círculo de Investigación del Bambú Universidad Nacional Agraria La Molina(UNALM)Lima15026Perú Instituto de Materiales de Misiones(IMAM) Universidad Nacional de Misiones(UNaM)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Facultad de Ciencias ExactasQuímicas y Naturales(FCEQYN)Programa de Celulosa y Papel(PROCyP)Posadas3300Argentina Instituto de Materiales de Misiones(IMAM) Universidad Nacional de Misiones(UNaM)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Facultad de Ciencias Forestales(FCF)Eldorado3380Argentina

Non-traditional lignocellulosic materials are a significant resource for producing high-value products, including nanocellulose. This work studied the nanocellulose obtention from chemical pulps of the two fast-growing bamboo species, Guadua trinii , and Guadua angustifolia . Chemical pulps were produced by soda-anthraquinone (S) pulping from both autohydrolysis-pretreated (H) and unpretreated bamboo chips. Autohydrolysis-pretreated (SHP) and unpretreated soda-anthraquinone (AQ) (SP) pulps were characterized by yield, Kappa number, alpha, beta, and gamma cellulose, degree of polymerization, water retention value, and crystallinity. The nanocellulose was produced by a sequential chemical oxidation treatment (2,2,6,6-tetramethylpiperidine-1-oxyl, TeMPO reagent) and mechanical nanofibrillation. Nanocellulose was characterized by carboxylic group content and viscosity. The results revealed that autohydrolysis pretreatment resulted in a higher hemicelluloses extraction in G. angustifolia . In contrast, the pulping yield of unpretreated samples was higher for G. trinii , and the soda-AQ pulps from this species exhibited better delignification than the autohydrolysis-pretreated pulps. The crystallinity index values of the obtained pulps were high (>80%), and the alpha-cellulose contents were similar. The viscosities of the aqueous nanocellulose suspensions were higher for the nanocellulose solutions obtained from the unpretreated soda-AQ pulps. Besides, nanocellulose from G. trinii unpretreated soda-AQ pulps had a higher rate of carboxylic groups. The results of this work are significant in assessing the potential of both bamboo species as a source of high-value products within the biorefinery framework because the viscosities of the aqueous nanocellulose suspensions depend on the size and shape of nanofibrils. It has significant importance for industrial unit operations and potential applications.

关键词： Natural fiber Guadua angustifolia Guadua trinii soda-anthraquinone pulp nanocellulose

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Hybrid Cybersecurity Algorithm for Digital Image Transmission over Advanced Communication Channel Models

引用

Computers, Materials & Continua 2024年第4期79卷 201-241页

作者： Naglaa F.Soliman Fatma e.Fadl-Allah Walid el-Shafai Mahmoud I.Aly Maali Alabdulhafith Fathi e.Abd el-Samie Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of electronics and Communications Faculty of EngineeringZagazig UniversityZagazig44519Egypt Security engineering Lab Computer Science DepartmentPrince Sultan UniversityRiyadh11586Saudi Arabia Department of electronics and electrical Communications engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt

The efficient transmission of images,which plays a large role inwireless communication systems,poses a significant challenge in the growth of multimedia ***-quality images require well-tuned communication *** Single Carrier Frequency Division Multiple Access(SC-FDMA)is adopted for broadband wireless communications,because of its low sensitivity to carrier frequency offsets and low Peak-to-Average Power Ratio(PAPR).Data transmission through open-channel networks requires much concentration on security,reliability,and *** data need a space away fromunauthorized access,modification,or *** requirements are to be fulfilled by digital image watermarking and *** paper ismainly concerned with secure image communication over the wireless SC-FDMA systemas an adopted communication *** introduces a robust image communication framework over SC-FDMA that comprises digital image watermarking and encryption to improve image security,while maintaining a high-quality reconstruction of images at the receiver *** proposed framework allows image watermarking based on the Discrete Cosine Transform(DCT)merged with the Singular Value Decomposition(SVD)in the so-called DCT-SVD *** addition,image encryption is implemented based on chaos and DNA *** encrypted watermarked images are then transmitted through the wireless SC-FDMA *** linearMinimumMean Square error(MMSe)equalizer is investigated in this paper to mitigate the effect of channel fading and noise on the transmitted *** subcarrier mapping schemes,namely localized and interleaved schemes,are compared in this *** study depends on different channelmodels,namely PedestrianAandVehicularA,with a modulation technique namedQuadratureAmplitude Modulation(QAM).extensive simulation experiments are conducted and introduced in this paper for efficient transmission of encrypted watermarked *** addition,different variants of SC-FDMA bas

关键词： Cybersecurity applications image transmission channel models modulation techniques watermarking and encryption

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insm1:orchestrating cellular mimicry in the thymus medulla

引用

Cellular & Molecular Immunology 2024年第4期21卷 414-416页

作者： K.D.James J.e.Cowan UCL Institute of Immunity and Transplantation The Pears BuildingRowland Hill StreetLondonNW32PPUK

The thymus is the primary production site for a functional and self-tolerant T-cell *** establishment of immune tolerance is mediated by the generation and presentation of tissue-restricted self-antigens(TRAs)by medullary thymic epithelial cells(mTeCs),which screen T-cell receptors for self-reactivity to eliminate autoreactive T *** studies have extended our understanding of mTeC heterogeneity by examining the mechanisms by which mTeCs mimic the peripheral self[1].

关键词： medullary eliminate restricted

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Management of obstructed colorectal carcinoma in an emergency setting:An update

引用

World Journal of Gastrointestinal Oncology 2024年第3期16卷 598-613页

作者： efstathios T Pavlidis Ioannis N Galanis Theodoros e Pavlidis 2nd Propedeutic Department of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colorectal carcinoma is common,particularly on the left *** 20%of patients,obstruction and ileus may be the first clinical manifestations of a carcinoma that has advanced(stage II,III or even IV).Diagnosis is based on clinical presentation,plain abdominal radiogram,computed tomography(CT),CT colonography and positron emission tomography/*** best management strategy in terms of short-term operative or interventional and long-term oncological outcomes re-mains *** the most common left-sided obstruction,the first choice should be either emergency surgery or endoscopic decompression by self-expen-dable metal stents or *** operative plan should be either one-stage or two-stage ***-stage resection with on-table bowel decompression and irrigation can be accompanied or not accompanied by proximal defunctioning stoma(colostomy or ileostomy).Primary anastomosis is more convenient but has increased risks of anastomotic leakage and ***-stage resection(Hart-mann’s procedure)is safer and the most widely used despite temporally affecting quality of *** control surgery in high-risk frail patients is less frequently performed since it can be successfully substituted with endoscopic stenting or *** the less common right-sided obstruction,one-stage surgical resection is more beneficial than endoscopic *** role of minimally invasive surgery(laparoscopic or robotic)is a subject of *** laparoscopic-assisted management is advantageous to some extent but requires much expertise due to inherent difficulties in dissecting the distended colon and the risk of rup-ture and subsequent septic *** decompressing stent as a bridge to elective surgery more substantially decreases the risks of morbidity and mortality than emergency surgery for decompression and has equivalent medium-term overall survival and disease-free survival *** combination with neoadjuvant chemotherapy or radiation may have a p

关键词： Acute abdomen Obstructive ileus Colorectal carcinoma emergency surgery Colectomy Intraluminal metal stents

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

LiDAR-based estimation of bounding box coordinates using Gaussian process regression and particle swarm optimization

引用

Biomimetic Intelligence & Robotics 2024年第1期4卷 24-35页

作者： Vinodha K. e.S.Gopi Tushar Agnibhoj Department of electronics and Communication engineering National Institute of Technology TiruchirappalliTamil Nadu620015India

Camera-based object tracking systems in a given closed environment lack privacy and *** this study,light detection and ranging(LiDAR)was applied to track objects similar to the camera tracking in a closed environment,guaranteeing privacy and *** primary objective was to demonstrate the efficacy of the proposed technique through carefully designed experiments conducted using two *** Scenario I,the study illustrates the capability of the proposed technique to detect the locations of multiple objects positioned on a flat surface,achieved by analyzing LiDAR data collected from several locations within the closed *** II demonstrates the effectiveness of the proposed technique in detecting multiple objects using LiDAR data obtained from a single,fixed ***-time experiments are conducted with human subjects navigating predefined *** individuals move within an environment,while LiDAR,fixed at the center,dynamically tracks and identifies their locations at multiple *** demonstrate that a single,strategically positioned LiDAR can adeptly detect objects in motion around ***,this study provides a comparison of various regression techniques for predicting bounding box *** process regression(GPR),combined with particle swarm optimization(PSO)for prediction,achieves the lowest prediction mean square error of all the regression techniques examined at *** tuning of GPR using PSO significantly minimizes the regression *** of the experiment pave the way for its extension to various real-time applications such as crowd management in malls,surveillance systems,and various Internet of Things scenarios.

关键词： LiDAR Data acquisition Bounding box Gaussian process regression Particle swarm optimization(PSO)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

New trends in diagnosis and management of gallbladder carcinoma

引用

World Journal of Gastrointestinal Oncology 2024年第1期16卷 13-29页

作者： efstathios T Pavlidis Ioannis N Galanis Theodoros e Pavlidis ^(nd)Propedeutic Department of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladder(GB)carcinoma,although relatively rare,is the most common biliary tree cholangiocarcinoma with aggressiveness and poor *** is closely associated with cholelithiasis and long-standing large(>3 cm)gallstones in up to 90%of *** other main predisposing factors for GB carcinoma include molecular factors such as mutated genes,GB wall calcification(porcelain)or mainly mucosal microcalcifications,and GB polyps≥1 cm in *** is made by ultrasound,computed tomography(CT),and,more precisely,magnetic resonance imaging(MRI).Preoperative staging is of great importance in decisionmaking regarding therapeutic *** staging is based on MRI findings,the leading technique for liver metastasis imaging,enhanced three-phase CT angiography,or magnetic resonance angiography for major vessel *** is also necessary to use positron emission tomography(PeT)-CT or ^(18)F-FDG PeT-MRI to more accurately detect metastases and any other occult deposits with active metabolic *** laparoscopy may detect dissemination not otherwise found in 20%-28.6%of *** treatment is needed,including surgical resection,targeted therapy by biological agents according to molecular testing gene mapping,chemotherapy,radiation therapy,and *** is of great importance to understand the updated guidelines and current treatment *** extent of surgical intervention depends on the disease stage,ranging from simple cholecystectomy(T1a)to extended resections and including extended cholecystectomy(T1b),with wide lymph node resection in every case or IV-V segmentectomy(T2),hepatic trisegmentectomy or major hepatectomy accompanied by hepaticojejunostomy Roux-Y,and adjacent organ resection if necessary(T3).Laparoscopic or robotic surgery shows fewer postoperative complications and equivalent oncological outcomes when compared to open surgery,but much attention must be paid to avoiding *** addition to surgery,novel targe

关键词： Biliary tract neoplasms extrahepatic cholangiocarcinoma Gallbladder carcinoma Gallbladder diseases Biliary tree diseases Gastrointestinal malignancies

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：