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现代制造 2004年第29期 60-61页

作者： Wolfram Blaesius e.rene baer

双轴半拖车式牵引车和三轴半挂车的结合使用是欧洲长途公路运输中的一种主要组合运输方式,这种运输组合在实际工作中仍具有进一步优化的潜力——不管是纯公路运输,还是先公路运输再与铁路和水路联运,或者先铁路和水路联运,再进行公路运... 详细信息

双轴半拖车式牵引车和三轴半挂车的结合使用是欧洲长途公路运输中的一种主要组合运输方式,这种运输组合在实际工作中仍具有进一步优化的潜力——不管是纯公路运输,还是先公路运输再与铁路和水路联运,或者先铁路和水路联运,再进行公路运输(KV)等。

关键词：双轴半拖车式牵引车三轴半挂车载荷分配公路运输组合运输方式

MODeLING SPATIAL AND TeMPORAL VARIATION OF A POLLUTANT IN WATeR eNVIRONMeNT USING THe CUBIC SPLINe SCHeMe

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Journal of Hydrodynamics 2006年第6期18卷 688-697页

作者： YAN Min KAHAWITA rene College of Architecture and Civil engineering Zhejiang University of Technology Hangzhou 310014 China Department of Civil Geological and Mining Engineering Ecole Polytechnique de Montréal Université deMontr6al Quebec H3C 3A7 Canada Department of Civil Geological and Mining Engineering Ecole Polytechnique de Montréal Université de Montréal Quebec H3C 3A7 Canada

The cubic spline integration scheme has been successfully applied for the first time to obtain solutions for the two-dimensional shallow water wave and transport equations. Its principal advantages are its high accuracy, low computational cost, and flexibility of application. The study quantitatively analyzed and predicted the variation in time and space of a solid pollutant in water environment. The infiltration, adsorption, solubility, advection, and diffusion related factors at different spatial and temporal scales were taken into consideration in the model. experiments were conducted in this study to examine the capabilities of the cubic spline scheme, The correspondence between the numerical results and the experimental data was fair, The results were also compared with the numerical results obtained using finite difference schemes with good agreement.

关键词： numerical model cubic spline scheme,hydraulics environment pollution

Measuring the influence of a mutual support educational intervention within a nursing team

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International Journal of Nursing Sciences 2014年第1期1卷 15-22页

作者： rene´e Bridges Gwen Sherwood Carol Durham University of North Carolina at Chapel Hill School of NursingChapel HillNCUnited States Rex Healthcare RaleighNCUnited States

Background:Teamwork is essential to provide the highest quality of care for *** supported within a nursing unit is a significant factor in nursing satisfaction,intention to remain in the job,and the capacity to provide safe patient care by Aiken et al[1].Purpose:This study examined mutual support among a nursing team to measure the influence of an educational intervention focusing on Mutual Support from the Team STePPS curriculum by Agency for Healthcare Research and Quality,AHRQ[2].Methods:The study design used a Likert scale survey,the Nursing Teamwork Survey,before and following an education intervention adapted from the Team STePPS curriculum on Mutual *** data from the 41 participants were analyzed for impact on educational background,roles and responsibilities,age,and other ***:Pre-Post education intervention results varied among the survey items,although scores demonstrated heightened awareness of teamwork following the educational *** subscale of Backup illustrated the strongest ***:The study demonstrates that education can have an impact on perceptions and awareness of mutual support among nursing team *** survey instrument can be used effectively to inform leadership areas for improvement and staff development in the effort to improve team coordination and mutual support.

关键词： Mutual support Nursing teams Team STePPS Teamwork Safety

Hepatic organ protection:From basic science to clinical practice

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World Journal of Gastroenterology 2010年第48期16卷 6044-6045页

作者： rene Schmidt Department of Anesthesiology and Critical Care Medicine Freiburg University Medical Center

Hepatic ischemia and reperfusion (I/R) injury during liver surgery is still the main cause of postoperative liver failure and the subsequent rise of mortality in these patients. During the last few years, a multitude of underlying mechanisms have been extensively characterized and many different protective approaches have been evaluated under experimental conditions. Some of them have already found their way into small sized clinical trials. In this Topic Highlight series of articles, we present recent insights into promising protective concepts including the regulation and optimization of hepatic blood flow, molecular mechanisms of preconditioning and pharmacological approaches with the aim of limiting hepatic I/R injury. Leading international experts present the latest experimental evidence in their fields stressing clinically relevant ideas, which are now on the edge of entering clinical practice.

关键词： Heme oxygenase-1 Hepatectomy Hepatic organ protection Ischemia/reperfusion injury Liver blood flow Liver transplantation Preconditioning

Do people communicate about their whereabouts? Investigating the relation between user-generated text messages and Foursquare check-in places

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Geo-Spatial Information Science 2018年第3期21卷 159-172页

作者： Ming Li rene Westerholt Alexander Zipf Institute of Geography Heidelberg UniversityHeidelbergGermany

The social functionality of places(***,restaurant)partly determines human behaviors and reflects a region’s functional *** descriptions of places are thus valuable to a range of studies of humans and geographic *** their potential impacts on human verbalization behaviors,one possibility is to link the functions of places to verbal representations such as users’postings in location-based social networks(LBSNs).In this study,we examine whether the heterogeneous user-generated text snippets found in LBSNs reliably reflect the semantic concepts attached with check-in *** investigate Foursquare because its available categorization hierarchy provides rich a-priori semantic knowledge about its check-in places,which enables a reliable verification of the semantic concepts identified fromuser-generated text snippets.A latent semantic analysis is conducted on a large Foursquare check-in *** results confirm that attached text messages can represent semantic concepts by demonstrating their large correspondence to the official Foursquare venue *** further elaborate the representativeness of text messages,this work also performs an investigation on the textual terms to quantify their abilities of representing semantic concepts(i.e.,representativeness),and another investigation on semantic concepts to quantify how well they can be represented by text messages(i.e.,representability).The results shed light on featured terms with strong locational characteristics,as well as on distinctive semantic concepts with potentially strong impacts on human verbalizations.

关键词： Text mining latent semantic analysis semantic concepts Foursquare location-based social network(LBSN)

Taking advantage of drug resistance, a new approach in the war on cancer

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Frontiers of Medicine 2018年第4期12卷 490-495页

作者： Liqin Wang rene Bernards Division of Molecular Carcinogenesis Oncode Institute The Netherlands Cancer Institute Plesmanlaan 121 1066 CX Amsterdam The Netherlands

Identification of the driver mutations in cancer has resulted in the development of a new category of molecularly targeted anti-cancer drugs. However, as was the case with conventional chemotherapies, the effectiveness of these drugs is limited by the emergence of drug-resistant variants. While most cancer therapies are given in combinations that are designed to avoid drug resistance, we discuss here therapeutic approaches that take advantage of the changes in cancer cells that arise upon development of drug resistance. This approach is based on notion that drug resistance comes at a fitness cost to the cancer cell that can be exploited for therapeutic benefit. We discuss the development of sequential drug therapies in which the first therapy is not given with curative intent, but to induce a major new sensitivity that can be targeted with a second drug that selectively targets the acquired vulnerability. This concept of collateral sensitivity has hitherto not been used on a large scale in the clinic and holds great promise for future cancer therapy.

关键词： cancer drug resistance genetic screens senescence targeted therapy

A Roadmap toward engineered Nitrogen-Fixing Nodule Symbiosis

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Plant Communications 2020年第1期1卷 131-146页

作者： Rik Huisman rene Geurts Wageningen University Department of Plant SciencesLaboratory of Molecular BiologyDroevendaalsesteeg 1Wageningen 6708PBThe Netherlands

In the late 19th century,it was discovered that legumes can establish a root nodule endosymbiosis with nitrogen-fixing *** after,the question was raised whether it is possible to transfer this trait to non-leguminous *** the past century,an ever-increasing amount of knowledge provided unique insights into the cellular,molecular,and genetic processes controlling this *** addition,recent phylogenomic studies uncovered several genes that evolved to function specifically to control nodule formation and bacterial ***,despite this massive body of knowledge,the long-standing objective to engineer the nitrogen-fixing nodulation trait on nonleguminous crop plants has not been achieved *** this review,the unsolved questions and engineering strategies toward nitrogen-fixing nodulation in non-legume plants are discussed and highlighted.

关键词： nodulation legumes actinorhizal plants Parasponia engineering nitrogen fixation

enhancing perianal disease management with integrated physical and psychological approaches

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World Journal of Clinical Cases 2025年第2期13卷 59-63页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal *** study sheds light on how illness perception,anxiety,and depression significantly influence recovery *** et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor *** article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for *** study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.

关键词： Perianal disease Post-operative recovery Anxiety Depression Pain management emotional well-being Multidisciplinary approach

Alternative approaches for estimating missing climate data:application to monthly precipitation records in South- Central Chile

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Forest ecosystems 2018年第4期5卷 390-399页

作者： Alonso Barrios Guillermo Trincado rene Garreaud escuela de Graduados Facultad de Ctencias Forestales y Recursos Naturales Universidad Austral de ChileBox 567ValdiviaChile Departamento de Ciencias Forestales Facuitad de Ingenieria ForestalUnlversidad del Tolima Box 6299 Ibague Colombia Instituto de Bosques y Sociedad Facultad de Ciencias Forestales y Recursos NaturalesUniversidad Austraide ChileBox 567 ValdiviaChile Departamento de Geofistca Facultad de Ciencias Fisicas y MatematicasUniversidad de ChileSantiagoChile

Background: Over the last decades interest has grown on how climate change impacts forest resources. However,one of the main constraints is that meteorological stations are riddled with missing climatic data. This study compared five approaches for estimating monthly precipitation records: inverse distance weighting(IDW), a modification of IDW that includes elevation differences between target and neighboring stations(IDW_m), correlation coefficient weighting(CCW), multiple linear regression(MLR) and artificial neural networks(ANN).Methods: A complete series of monthly precipitation records(1995-2012) from twenty meteorological stations located in central Chile were used. Two target stations were selected and their neighboring stations, located within a radius of25 km(3 stations) and 50 km(9 stations), were identified. Cross-validation was used for evaluating the accuracy of the estimation approaches. The performance and predictive capability of the approaches were evaluated using the ratio of the root mean square error to the standard deviation of measured data(RSR), the percent bias(PBIAS), and the NashSutcliffe efficiency(NSe). For testing the main and interactive effects of the radius of influence and estimation approaches,a two-level factorial design considering the target station as the blocking factor was ***: ANN and MLR showed the best statistics for all the stations and radius of influence. However, these approaches were not significantly different with IDW_m. Inclusion of elevation differences into IDW significantly improved IDW_m estimates. In terms of precision, similar estimates were obtained when applying ANN, MLR or IDW_m, and the radius of influence had a significant influence on their estimates, we conclude that estimates based on nine neighboring stations located within a radius of 50 km are needed for completing missing monthly precipitation data in regions with complex ***: It is concluded that approaches based on ANN

关键词： Climatological data Cross-validation Artificial neural networks Multiple linear regression

Influence of the Iron Anisothermal Sintering on the Characteristic of the Hollow Cathode Discharge

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材料热处理学报 2004年第5期25卷 83-87页

作者： BRUNATTO Silvio Francisco MUZART Joel Louis rene Department of Mechanical engineering UFPR 81531-990 Curitiba-PR BrazilDepartment of Mechanical Engineering UFSC 88040-900 Florianopolis-SC Brazil

This work studies the influence of anisothermal iron sintering process on hollow cathode discharge characteristics. Two independent cathodes form an annular discharge. The pressed cylindrical iron powder sample, acting as central cathode, was placed concentrically in the interior of an external cathode. The external cathode, machined from an AISI 310 steel bar, besides acting to confine the geometry of the plasma, can also acts as a source of alloying elements. The sample heating is a function of the ion bombardment energy and, so, of the discharge electrical parameters: current (or current density) and the effective potential applied to the cathode. Successive anisothermal sintering is performed in a same sample until the reproducibility of the electrical parameters being obtained. The heating experiments up to 1250 °C, in a gas mixture of 80% Ar + 20% H2, at pressure of 133 Pa, at flow of 2xlO"6 mV, with an inter-cathode radial space of 5.8 mm, were carried out. It was verified the metallurgical evolution of the iron sample sintering process influences the current-?0n (time switched-on of the pulse) characteristics of the discharge.

关键词：空心阴极放电等离子体焊结烧结铁溅射非等温焙烧