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Al-driven analysis establishes the single base substitution signatures as personalized prognostic predictors for five-year survival of gastric cancer

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Genes & Diseases 2024年第4期11卷 73-76页

作者： Zhenzhang li lingqing Xu Wen luo Shaoan Zhangg Chunyu Hou Xiaohong Xu ,Xubei peng e.Shiju Janak l.pathak Shizhen Zhang Jiawei liu linhai li Yang li School of Biomedical engineering The Sixth Affiliated HospitalGuangzhou Medical UniversityGuangzhouGuangdong 511436China College of Mathematics and Systems Science Guangdong Polytechnic Normal UniversityGuangzhouGuangdong 510665China The Second Affiliated Hospital Guangzhou Medical UniversityGuangzhouGuangdong 510260China Center for learning Sciences and Technologies The Chinese University of Hong KongShatinNew Territories 999077China Affiliated Stomatology Hospital of Guangzhou Medical University Guangzhou Medical UniversityGuangzhouGuangdong 510182China International School of photonics Cochin University of Science and TechnologyKochiKerala 682022India

Al-driven genetic engineering,as a burgeoning diagnostic tool,can offer predictive information on the five-year survival rate(FYSR)in the setup of a prognostic therapeutic *** approach provides the individuality and accuracy of prognosis for FYSR of gastric cancer(GC).Unlike traditional neoplasm staging criteria,our technique ensures accuracy and individuality without relying on statistical data and empirical study.

关键词： cancer gastric prognosis

Commentary on "Association of daily sitting time and leisure-time physical activity with body fat among ***"

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Journal of Sport and Health Science 2024年第2期13卷 127-129页

作者： Barbara e.Ainsworth School of exercise and Health Shanghai University of SportShanghai 200438China

In their study,association of daily sitting time and leisure-time physical activity (lTpA) with body fat among ***,liao et al.^(1) analyzed data from the 2011-2018 National Health and examination Survey to examine associations between h/day sitting,meeting (or not meeting) the *** Activity Guidelines of≥150 min/week of moderate-and vigorous-intensity lTpA,and combinations of sitting time and lTpA on totaland trunk percent body fat (BF%).

关键词： U.S. adult among

Corrosion testing of X52 and X80 steels immersed in stimulated emulsions using a real petroleum sample

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petroleum Research 2024年第2期9卷 304-316页

作者： l.M.Quej-Ake J.l.Alamilla A.Contreras Instituto Mexicano del petróleo Eje Central Lázaro CárdenasNorte 152San Bartolo AtepehuacanGustavo A.MaderoCiudad de MéxicoC.P.07730México

The aim of this study is to evaluate the internal corrosion process on X52 and X80 steels/real petroleum interfaces containing condensed hydrocarbon plus oilfield-produced water,which were subjected to stimulated emulsions using 50/50 vol ratio mixtures at 45℃,different hydrodynamic conditions,1 h,and 24 h.A washing process by using deionized water was proposed to simulate and identify the corrosiveness of the hydrocarbon phase after 24 h of exposure *** characterization by electrochemical impedance spectroscopy and the monitoring of the polarization curves indicated that X80 steel/oilfield-produced water interfaces were more susceptible to corrosion than X52 steel exposed to oilfield-produced *** combined speed rotation of 600 rpm using a magnetic stirrer+600 rpm using a rotating disk electrode decreased the corrosion rate on X52 *** stimulated emulsions made of hydrocarbon+oilfield-produced water and hydrocarbon+deionized water at 24 h increased the corrosion rate on X80 steel(0.34 mm/year and 0.43 mm/year,respectively),promoting the formation of erosion and pitting *** types of corrosion depended mainly on the physicochemical properties of the hydrocarbon,oilfield-produced water,exposure times,and hydrodynamic systems in which the hydrocarbon was studied.

关键词： Corrosion emulsions X52 steel X80 steel

Assessment of portable FTIR and Raman spectroscopy for the detection of 2,3-dimethyl-2,3-dinitrobutane(DMDNB)in plastic explosives

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Defence Technology（防务技术） 2024年第4期34卷 11-18页

作者： Jacky Cailes Robert Dunsmore Kathryn l.linge ChemCentre PO Box 1250PerthAustralia

The Marplex Convention was established to prevent the manufacture of unmarked plastic explosives and stipulates that a volatile detection agent must be added at the time of ***,to-date,laboratory testing remains the internationally accepted practice for identifying and quantifying the taggants stipulated in the *** this project,portable FTIR and Raman instruments were tested for their ability to detect 2,3-dimethyl-2,3-dinitrobutane(DMDNB),the chemical marker incorporated in plastic explosives that are manufactured within *** both FTIR and Raman instruments detected solid DMDNB(98%purity),field analysis of plastic explosives at an Australian Defence establishment showed that both FTIR and Raman spectra were matched the relevant explosive(RDX or peTN),rather than the DMDNB *** all three plastic explosives tested,the concentration of DMDNB was measured by SpMe-GC-MS to be between 1.8 and 2%,greater than the minimum 1%concentration stipulated by the Marplex *** testing with a plastic explosive analogue confirmed that the minor absorption peaks that would characterize low concentrations of DMDNB were masked by absorption bands from other compounds within the ***,while both FTIR and Raman spectroscopy are suitable for detection of plastic explosives,neither rely on the presence of DMDNB for *** is likely that similar results would be found for other taggants stipulated by the Marplex Convention,given they are also present in concentrations less than 1%.

关键词： explosive ICAO taggants 2,3-Dimethyl-2,3-dinitrobutane(DMDNB) Fourier transform infrared(FTIR) Raman

Nonaqueous potassium-ion full-cells:Mapping the progress and identifying missing puzzle pieces

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Journal of energy Chemistry 2024年第6期93卷 384-399,I0010页

作者： Badre larhrib louiza larbi lénaïc Madec Universite de pau et des pays de l’Adour E2S UPPACNRSIPREMPauFrance Universitéde Haute-Alsace Institut de Science des Matériaux de Mulhouse(IS2M)CNRS UMR 7361F-68100 MulhouseFrance Universitéde Strasbourg F-67081 StrasbourgFrance Réseau sur le Stockage electrochimique de l’energie CNRS FR3459AmiensFrance Institut des Matériaux Jean Rouxel(IMN) CNRS UMR 6502Univ.Nantes44322 Cedex 3 NantesFrance

This review addresses the growing interest for potassium-ion full-cells(KIFCs)in view of the transition from potassium-ion half-cells(KIHCs)toward commercial K-ion batteries(KIBs).It focuses on the key parameters of KIFCs such as the electrode/electrolyte interfaces challenge,major barriers,and recent advancements in *** strategies for enhancing KIFC performance,including interfaces co ntrol,electrolyte optimization,electrodes capacity ratio,electrode material screening and electrode design,are *** review highlights the need to evaluate KIBs in full-cell configurations as half-cell results are strongly impacted by the K metal *** also emphasizes the importance of understanding solid electrolyte interphase(SeI)formation in KIFCs and explores promising nonaqueous as well as quasiand all-solid-state electrolytes *** review thus paves the way for practical,cost-effective,and scalable KIBs as energy storage systems by offering insights and guidance for future research.

关键词： K-ion full-cells potassium-ion batteries Cross-talk Solid-state batteries potassium reactivity electrolyte design electrode design

positive health:An integrated quantitative approach in patients with chronic gastrointestinal and hepato-pancreatico-biliary disorders

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World Journal of Gastroenterology 2024年第28期30卷 3418-3427页

作者： Anja H W M lemlijn-Slenter Karolina Ap Wijnands Gijs van der Hamsvoort luuk p van Iperen Nico Wolter Angelique e de Rijk Ad AM Masclee Department of Social Medicine Faculty of HealthMedicine and Life sciencesCare and Public Health Research Institute Maastricht UniversityMaastricht 6200 MDLimburgNetherlands Division of Gastroenterology and Hepatology Department of Internal MedicineSchool of Nutrition and Translational Research in MetabolismMaastricht 6200 MDLimburgNetherlands Social Medical Affairs Employee Insurance Agency(UWV)Heerlen 6400 ACLimburgNetherlands Department of Research Academic Knowledge Center Work and Health South-East Netherlands(AKAG-ZON)Heerlen 6400 ACLimburgNetherlands

BACKGROUND The concept of positive health(pH)supports an integrated approach for patients by taking into account six dimensions of *** approach is especially relevant for patients with chronic *** gastrointestinal and hepatopancreatico-biliary(GI-HpB)disorders are among the top-6 of the most prevalent chronically affected organ *** impact of chronic GI-HpB disorders on individuals may be disproportionally high because:(1)The affected organ system frequently contributes to a malnourished state;and(2)persons with chronic GIHpB disorders are often younger than persons with chronic diseases in other organ *** To describe and quantify the dimensions of pH in patients with chronic GI-HpB *** prospective,observational questionnaire study performed between 2019 and 2021 in 235 patients with a chronic GIHpB disorder attending the Outpatient Department of the Maastricht University Medical *** questionnaires and data from patient files were used to quantify the six dimensions of *** consistency was tested with McDonald’s ***-order pearson correlations and t-tests were used to assess associations and differences.A p valueered *** The GI-HpB patients scored significantly worse in all dimensions of pH compared to control data or norm scores from the general *** quality of life,participation and daily functioning,GI-HpB patients scored in the same range as patients with chronic disorders in other organ systems,but depressive symptoms(in 35%)and malnutrition(in 45%)were more frequent in patients with chronic GI-HpB *** scores between the six dimensions were only very weak to weak,forcing us to quantify each domain *** All six dimensions of pH are impaired in the GI-HpB *** and depressive symptoms are more prevalent compared to patients with chronic disorders in other organ systems.

关键词： positive health Chronic gut disorders Gastrointestinal disorders Hepato-pancreatico-biliary disorders Integrated care

Guaranteed Cost Attitude Tracking Control for Uncertain Quadrotor Unmanned Aerial Vehicle Under Safety Constraints

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Ieee/CAA Journal of Automatica Sinica 2024年第6期11卷 1447-1457页

作者： Qian Ma peng Jin Frank l.lewis School of Automation Nanjing University of Science and TechnologyNanjing 210094China UTA Research Institute University of Texas at ArlingtonFort WorthTexas 76118 USA Ieee

In this paper,guaranteed cost attitude tracking con-trol for uncertain quadrotor unmanned aerial vehicle(QUAV)under safety constraints is ***,an augmented system is constructed by the tracking error system and reference *** transformation aims to convert the tracking control prob-lem into a stabilization control ***,control barrier function and disturbance attenuation function are designed to characterize the violations of safety constraints and tolerance of uncertain disturbances,and they are incorporated into the reward function as penalty *** on the modified reward function,the problem is simplified as the optimal regulation problem of the nominal augmented system,and a new Hamilton-Jacobi-Bellman equation is ***,critic-only rein-forcement learning algorithm with a concurrent learning tech-nique is employed to solve the Hamilton-Jacobi-Bellman equa-tion and obtain the optimal *** proposed algorithm can not only ensure the reward function within an upper bound in the presence of uncertain disturbances,but also enforce safety *** performance of the algorithm is evaluated by the numerical simulation.

关键词： Attitude tracking control quadrotor unmanned aerial vehicle(QUAV) reinforcement learning safety constraints uncertain disturbances.

Approximate contact solutions for non-axisymmetric homogeneous and power-law graded elastic bodies:A practical tool for design engineers and tribologists

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Friction 2024年第2期12卷 340-355页

作者： Valentin l.pOpOV Qiang lI emanuel WIlleRT Institute of Mechanics Technische Universität BerlinBerlin 10623Germany

In two recent papers,approximate solutions for compact non-axisymmetric contact problems of homogeneous and power-law graded elastic bodies have been suggested,which provide explicit analytical relations for the force–approach relation,the size and the shape of the contact area,as well as for the pressure distribution *** solutions were derived for profiles,which only slightly deviate from the axisymmetric *** the present paper,they undergo an extensive testing and validation by comparison of solutions with a great variety of profile shapes with numerical solutions obtained by the fast Fourier transform(FFT)-assisted boundary element method(BeM).examples are given with quite significant deviations from axial symmetry and show surprisingly good agreement with numerical solutions.

关键词： normal contact non-axisymmetric indenter extremal principle generalized method of dimensionality reduction(MDR) functional elastic grading

OptoGpT: A foundation model for inverse design in optical multilayer thin film structures

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Opto-electronic Advances 2024年第7期7卷 4-16页

作者： Taigao Ma Haozhu Wang l.Jay Guo Department of physics University of MichiganAnn ArborMichigan 48109USA Department of electrical engineering and Computer Science University of MichiganAnn ArborMichigan 48109USA

Optical multilayer thin film structures have been widely used in numerous photonic ***,existing inverse design methods have many drawbacks because they either fail to quickly adapt to different design targets,or are difficult to suit for different types of structures,e.g.,designing for different materials at each *** methods also cannot accommodate versatile design situations under different angles and *** addition,how to benefit practical fabrications and manufacturing has not been extensively considered *** this work,we introduce OptoGpT(Opto Generative pretrained Transformer),a decoder-only transformer,to solve all these drawbacks and issues simultaneously.

关键词： multilayer thin film structure inverse design foundation models deep learning structural color