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World Journal of Transplantation 2024年第1期14卷 1-8页

作者： Cristian lindner Raúl Riquelme Rodrigo San Martín Frank Quezada Jorge Valenzuela Juan p Maureira Martín einersen Department of Radiology Faculty of MedicineUniversity of ConcepciónConcepción 4030000Chile Department of Radiology Hospital Clínico Regional Guillermo Grant BenaventeConcepción 4030000Chile Department of Statistics Catholic University of MauleTalca 3460000Chile Neurovascular Unit Department of RadiologyHospital Clínico Regional Guillermo Grant BenaventeConcepción 4030000Chile

Hepatic artery thrombosis(HAT)is a devastating vascular complication following liver transplantation,requiring prompt diagnosis and rapid revascularization treatment to prevent graft *** present,imaging modalities such as ultrasound,computed tomography,and magnetic resonance play crucial roles in diagnosing *** imaging techniques have improved sensitivity and specificity for HAT diagnosis,they have limitations that hinder the timely diagnosis of this *** this sense,the emergence of artificial intelligence(AI)presents a transformative opportunity to address these diagnostic *** development of machine learning algorithms and deep neural networks has demonstrated the potential to enhance the precision diagnosis of liver transplant complications,enabling quicker and more accurate detection of *** article examines the current landscape of imaging diagnostic techniques for HAT and explores the emerging role of AI in addressing future challenges in the diagnosis of HAT after liver transplant.

关键词： liver transplantation postoperative complications Hepatic artery Thrombosis Radiology Artificial intelligence

Advances in spinal cord injury:insights from non-human primates

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Neural Regeneration Research 2024年第11期19卷 2354-2364页

作者： Gaetan poulen Florence e.perrin University of Montpellier INSERMEPHEMontpellierFrance Department of Neurosurgery Gui de Chauliac HospitalMontpellier University Medical CenterMontpellierFrance Institut Universitaire de France(IUF) ParisFrance

Spinal cord injury results in significant sensorimotor deficits,currently,there is no curative treatment for the symptoms induced by spinal cord *** and pre-clinical research on spinal cord injury relies on the development and characterization of appropriate animal *** models should replicate the symptoms observed in human,allowing for the exploration of functional deficits and investigation into various aspects of physiopathology of spinal cord ***-human primates,due to their close phylogenetic association with humans,share more neuroanatomical,genetic,and physiological similarities with humans than ***,the responses to spinal cord injury in nonhuman primates most likely resemble the responses to traumatism in *** this review,we will discuss nonhuman primate models of spinal cord injury,focusing on in vivo assessments,including behavioral tests,magnetic resonance imaging,and electrical activity recordings,as well as ex vivo histological ***,we will present therapeutic strategies developed in non-human primates and discuss the unique specificities of non-human primate models of spinal cord injury.

关键词： behavior cellular analysis non-human primates spinal cord injury tissue analysis

Cognition and movement in neurodegenerative disorders:a dynamic duo

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Neural Regeneration Research 2024年第10期19卷 2101-2102页

作者： Marit F.l.Ruitenberg Department of Health Medical and NeuropsychologyLeiden UniversityLeidenthe Netherlands leiden Institute for Brain and Cognition Leidenthe Netherlands

people with neurodegenerative disorders often experience problems across a variety of functional domains,including cognition,movement,and psychosocial *** classification of these disorders is based on the phenotypical manifestations that represent the most prominent clinical *** example,parkinson's disease and Huntington's disease are typically regarded as movement disorders,whereas Alzheimer's disease(AD) and other dementias are regarded as cognitive disorders.

关键词： disorders Huntington degenerative

On Differential equations of Integrable Billiard Tables

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Acta Mathematica Sinica,english Series 2024年第1期40卷 417-424页

作者： Vladimir DRAGOVIC Andrey e.MIRONOV Department of Mathematical Sciences The University of Texas at DallasRichardson TXUSA Mathematical Institute SANU BelgradeSerbia Novosibirsk State University NovosibirskRussia Sobolev Institute of Mathematics of the Siberian Branch of the Russian Academy of Sciences NovosibirskRussia

We introduce a method to find differential equations for functions which define tables,such that associated billiard systems admit a local first *** illustrate this method in three situations:the case of(locally)integrable wire billiards,for finding surfaces in R^(3)with a first integral of degree one in velocities,and for finding a piece-wise smooth surface in R^(3)homeomorphic to a torus,being a table of a billiard admitting two additional first integrals.

关键词： polynomial first integrals wire billiards piece-wise smooth surfaces

palladium-catalyzed S_(N)2 glycosylation of phenols

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Science China Chemistry 2024年第4期67卷 1037-1038页

作者： Yu Zhu p.Andrew evans Department of Chemistry Queen’s University90 Bader LaneKingstonK7L 3N6Canada Xiangya School of pharmaceutical Sciences Central South UniversityChangsha 410013China

Glycosides are essential structural motifs present in an array of important medicines,materials,and natural products[1].Nevertheless,the chemo-and stereoselective construction of the glycosidic linkage is a long-standing challenge because relatively minor variations in the glycosyl donor or acceptor’s structure can impact stereoselectivity,thus influencing the product's functional properties.

关键词： properties palladium catalyzed

promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents

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Neural Regeneration Research 2024年第8期19卷 1835-1841页

作者： Irene Navarro-lobato Mariam Masmudi-Martín Manuel F.lópez-Aranda Juan F.lópez-Téllez Gloria Delgado pablo Granados-Durán Celia Gaona-Romero Marta Carretero-Rey Sinforiano posadas María e.Quiros-Ortega Zafar U.Khan laboratory of Neurobiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain Department of Medicine Faculty of MedicineUniversity of MalagaMalagaSpain Centro de Investigación Biomédica en Red de enfermedades Neurodegenerativas(CIBeRNeD) Institute of Health Carlos IIIMadridSpain the Donders Institute for Brain Cognition and Behaviour Radboud UniversityNijmegenThe Netherlands the Brain Metastasis Group National Cancer Research Centre(CNIO)MadridSpain the Department of Neurobiology University of California-Los AngelesLos AngelesCAUSA

Memory deficit,which is often associated with aging and many psychiatric,neurological,and neurodegenerative diseases,has been a challenging issue for *** till now,all potential drug candidates have failed to produce satisfa ctory ***,in the search for a solution,we found that a treatment with the gene corresponding to the RGS14414protein in visual area V2,a brain area connected with brain circuits of the ventral stream and the medial temporal lobe,which is crucial for object recognition memory(ORM),can induce enhancement of *** this study,we demonstrated that the same treatment with RGS14414in visual area V2,which is relatively unaffected in neurodegenerative diseases such as Alzheimer s disease,produced longlasting enhancement of ORM in young animals and prevent ORM deficits in rodent models of aging and Alzheimer’s ***,we found that the prevention of memory deficits was mediated through the upregulation of neuronal arbo rization and spine density,as well as an increase in brain-derived neurotrophic factor(BDNF).A knockdown of BDNF gene in RGS14414-treated aging rats and Alzheimer s disease model mice caused complete loss in the upregulation of neuronal structural plasticity and in the prevention of ORM *** findings suggest that BDNF-mediated neuronal structural plasticity in area V2 is crucial in the prevention of memory deficits in RGS14414-treated rodent models of aging and Alzheimer’s ***,our findings of RGS14414gene-mediated activation of neuronal circuits in visual area V2 have therapeutic relevance in the treatment of memory deficits.

关键词： behavioral performance brain-derived neurotrophic factor cognitive dysfunction episodic memory memory circuit activation memory deficits memory enhancement object recognition memory prevention of memory loss regulator of G protein signaling

Complex-frequency waves:beat loss and win sensitivity

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light(Science & Applications) 2024年第2期13卷 181-183页

作者： Qingqing Cheng Tao l School of Optical-electrical and Computer engineering University of Shanghai for Science and TechnologyShanghai200093China Department of Respiratory Diseases and Critical Medicine Quzhou Hospital Affiliated to Wenzhou Medical UniversityQuzhou324000China National laboratory of Solid State Microstructures College of Engineering and Applied SciencesNanjing UniversityNanjing210093China

Recent experiments have demonstrated that synthesized complex-frequency waves can impart a virtual gain to molecule sensing systems,which can effectively restore information lost due to intrinsic molecular *** enhancement notably amplifies the signal of trace molecular vibrational fingerprints,thereby substantially improving the upper limit of sensitivity.

关键词： thereby Complex limit

phanerozoic co-evolution of O2-CO2 and ocean habitability

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National Science Review 2024年第06期 18-21页

作者： Zunli lu Rosalind e.M.Rickaby Jonathan l.payne Ashley N.prow Department of earth & environmental Sciences Syracuse University Department of earth Sciences University of Oxford Department of earth and planetary Sciences Stanford University

Atmospheric carbon dioxide and oxygen concentrations are partially linked via the geological cycle of organic carbon （Fig. 1A–C; e.g. CO2+H2O■CH2O+O2）. The history of these two biologically active components, controls on their concentrations, and implications for the complexity of the biosphere and habitability of earth have been hotly debated, but are generally considered independently.

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Organ Abscission in plants: With Special emphasis on Bell pepper

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phyton-International Journal of experimental Botany 2024年第7期93卷 1467-1484页

作者： Ramiro Reyes-Castro Héctor G.Núñez-palenius Juan I.Valiente-Banuet María e.Sosa-Morales Blanca e.Orosco-Alcalá Rafael Guzmán-Mendoza Graciela M.l.Ruiz-Aguilar Rogelio Costilla-Salazar life Sciences Division Universidad de GuanajuatoIrapuato36500México School of engineering and Sciences Tecnologico de MonterreyQuerétaro76130México

Bell pepper(Capsicum annuum l.),along with potato and tomato,is one of the three most cultivated vegetables in the *** pepper is worldwide accepted due to its characteristics of color,smell,ﬂavor,and *** pepper is also considered a nutritious food due to its vitamin and antioxidant *** Mexico,bell pepper production has a high value because it is grown for the international markets,particularly the United States of ***,the abscission ofﬂowers and fruits is a factor that limits the yield,hinders the planning of activities,and causes a variation in the prices of *** to the importance of this process,in this work we did a bibliometric analysis and literature review of scientiﬁc advances for the understanding of the abscission pro-cess in plants,and in particular for the bell ***,we introduce new perspectives that would help direct future research about organ abscission in ***,the lack of research that would further clarify abscis-sion process in the bell pepper plant is discussed.

关键词： Capsicum annuum abscission zone plant growth regulators environmental factors

Alzheimer's disease and low-dose radiation therapy:A new hope

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Radiation Medicine and protection 2024年第1期5卷 1-6页

作者： Neal e.Dunlap Robert p.Friedland lu Cai Department of Radiation Oncology University of Louisville School of MedicineLouisvilleKY40202USA Department of Neurology The University of Louisville School of MedicineLouisvilleKY40202USA pediatric Research Institute Departments of PediatricsPharmacology and ToxicologyUniversity of Louisville School of MedicineLouisvilleKY40202USA

The concept of low-dose radiation(lDR)-induced hormetic responses was initially observed approximately 70 years ago and systematically reviewed along with the discovery of lDR-induced adaptive responses in a cytogenetic in vitro study in *** the end of the 1990s,discussions regarding the potential applications of lDRinduced hormesis and adaptive responses for preventing or treating chronic diseases,such as Alzheimer’s disease(AD)had taken *** 2016,reports on radiotherapy for the subjects with AD and for genetic AD model mice were ***,several preclinical studies with animal models of AD and clinical studies in AD subjects were conducted.A significant milestone was achieved with the online availability of a new Systematic Review based on qualified publications from these preclinical and clinical *** mini-review provides a concise historical introduction to lDR-induced hormesis and adaptive responses with discussion of AD radiotherapy with either lDR or relatively high dose *** of this Systematic Review cover promising outcomes,challenges,and new questions,followed by discussion of potential mechanisms.

关键词： Alzheimer’s disease low-dose radiation Radiation adaptive response Radiation hormesis