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Differences of silicon photodiode spectral reflectance among the same batch

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Optoelectronics Letters 2008年第5期4卷 347-350页

作者： A.L.muoz Zurita J.Campos Acosta A.Pons Aglio A.Shcherbakov Department of Optics National Institute for AstrophysicsOptics and ElectronicsA.P.51 y 216Puebla72000México. CSIC-Institute for Applied Physics C.P.28006MadridSpain.

Photodiode＇s reflectance plays an important role regarding the relation between responsivity and the incident flux. In this work we analyze how the spectral reflectance changes among photodiodes from the same manufacturer and batch and how the reflectance of three standard photodiodes has drifted during six years. The results show that the reflectance changes from diode to diode within the same batch and also show that the reflectance ofphotodiodes changes on time. This ageing is spectraUy dependent.

关键词：硅发光二极管光谱反射率响应度

Rapid on-site evaluation of endoscopic-ultrasound-guided fine-needle aspiration diagnosis of pancreatic masses

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World Journal of Gastroenterology 2014年第28期20卷 9451-9457页

作者： Julio Iglesias-Garcia Jose Lario-Noia Ihab Abdulkader J enrique Domínguez-muoz Department of Gastroenterology and Hepatology Foundation for Research in Digestive DiseasesUniversity Hospital of Santiago de Compostela Department of Pathology University Hospital of Santiago de Compostela

endoscopic ultrasound (eUS) has become an essential tool for the study of pancreatic diseases. Specifically, eUS plays a pivotal role evaluating patients with a known or suspected pancreatic mass. In this setting, differential diagnosis remains a clinical challenge. eUS-guided fine-needle aspiration (FNA) and fine-needle biopsy (FNB) have been proven to be safe and useful tools in this setting. eUS-guided FNA and FNB, by obtaining cytological and/or histological samples, are able to diagnose pancreatic lesions with high sensitivity and specificity. In this context, several methodological features, trying to increase the diagnostic yield of eUS-guided FNA and FNB, have been evaluated. In this review, we focus on the role of rapid on-site evaluation (ROSe). From data reported in the literature, ROSe may increase diagnostic yield of eUS-FNA specimens by 10%-30%, and thus, diagnostic accuracy. However, we should point out that many recent studies have reported adequacy rates of > 90% without ROSe, indicating that, perhaps, at high-volume centers, ROSe may not be indispensable to achieve excellent results. The use of ROSe can be considered important during the learning curve of eUS-FNA, and also in hospital with diagnostic accuracy rates < 90%.

关键词： endoscopic-ultrasound-guided fine-needle aspiration Rapid on-site evaluation Solid pancreatic tumors Diagnostic accuracy

entry into Midgut epithelial Cells is a Key Step in the Selection of Genotypes in a Nucleopolyhedrovirus

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Virologica Sinica 2009年第4期24卷 350-358页

作者： Gabriel Clavijo Trevor Williams Delia muoz Miguel López-Ferber Primitivo Caballero Laboratorio de entomología Agrícola y Patología de Insectos Departamento de Producción Agraria Universidad Pública de Navarra Instituto de Agrobiotecnología CSIC Gobierno de Navarra Mutilva Baja Spain Instituto de ecología A.C. Xalapa Veracruz Mexico Laboratoire de Gènie de l'environnement Industriel Ecole de Mines d'Alès Alès France

An isolate of the Spodoptera frugiperda multiple nucleopolyhedrovirus comprises a stable proportion of deletion genotypes （e.g., SfNIC-C）, that lack pifl and pif2 rendering them noninfectious per os, and that survive by complementation with a complete genotype （SfNIC-B） in coinfected cells. To determine whether selection for particular ratios of complete and deletion genotypes occurs mainly during the establishment of the primary infection in insect midgut cells or during subsequent systemic infection, we examined genotype frequencies in insects that fed on OBs comprising different co-occluded mixtures of genotypes. Dramatic changes in genotype frequencies were observed between the OB inoculum and budded virus （BV） samples taken from larvae inoculated with OBs comprising 10% SfNIC-B ＋ 90% SfNIC-C indicating that a marked reduction of SfNIC-C genotype had occurred in the insect midgut due to the immediate elimination of all OBs that originated from cells that had been infected only by SfNIC-C. In contrast, immediate changes were not observed in OBs comprising mixtures of 50% SfNIC-B ＋ 50% SfNIC-C or those comprising 10% SfNIC-B ＋ 90% SfNIC-C as most of the OBs in these mixtures originated from cells that had been infected by both genotypes. Subsequent changes in genotypic frequencies during five days of systemic infection were fairly small in magnitude for all genotypic mixtures. We conclude that the prevalence of defective genotypes in the SfNIC population is likely determined by a balance between host selection against OBs produced in cells infected by SfNIC-C alone and within-host selection for fast-replicating deletion genotypes. The strength of intra-host selection is likely modulated by changes in MOI during the infection period.

关键词： Nucleopolyhedrovirus, Defective genotypes Infection Selection

Recent Advances in Synthesis and Properties of Hybrid Halide Perovskites for Photovoltaics

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Nano-Micro Letters 2018年第4期10卷 167-200页

作者： C.C.Vidyasagar Blanca M.muoz Flores Víctor M.Jimnez Prez Universidad Autónoma de Nuevo León Facultad de Ciencias Químicas Ciudad Universitaria School of Basic Sciences and Research in Chemistry Rani Channamma University

The progress made by the scientific community in emerging photovoltaic technologies over the past two decades has been outstanding. Numerous methods have been developed for the preparation of hybrid organic–inorganic perovskite solar cells. The power conversion efficiency has been up to 14% by a one-step vacuum deposition technique. A serious concern is the toxicity of the materials. In this review, several methods aimed at resolving these problems to some extent have been compiled, including eco-friendly synthesis. Further efficiency enhancements are expected following optimization, and a better fundamental understanding of the internal electron charge transfer, electron–hole diffusion to the corresponding layers, flexibility, and stability-dependent bandgaps is reported. This paper explores the green synthesis of organic–inorganic perovskites for industrialization. Concerning the above facts, a simple low-cost model called‘‘dispersed photovoltaic cells' ' is presented.

关键词： Perovskites Solar cells Organic–inorganic perovskites Synthetic routes Fluorescence

Male genitourinary schistosomiasis-related symptoms among long-term Western African migrants in Spain: a prospective population-based screening study

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贫困所致传染病(英文) 2024年第2期13卷 1-10页

作者： Roure Sílvia Vallès Xavier Pérez-Quílez Olga López-mu?oz Israel Chamorro Anna Abad elena Valerio Lluís Soldevila Laura espa?a Sergio Hegazy Alaa H. A. Fernández-Rivas Gema Gorriz ester Herena Dolores Oliveira Mário Miralles Maria Carme Conde Carmen Montero-Alia Juan José Fernández-Pedregal elia Miranda-Sánchez Jose Llibre Josep M. Isnard Mar Bonet Josep Maria estrada Oriol Prat Núria Clotet Bonaventura The Schisto-Stop study group International Health Program (PROSICS) Barcelona North Metropolitan Territorial Directorate for Infectious Diseases Catalan Institute for Health CAP La Salut Passatge dels Encants S/N Badalona Spain Fundació Lluita contra les Infeccions c/Can Ruti s/n Badalona Spain Infectious Diseases Department Hospital Universitari Germans Trias i Pujol c/Can Ruti s/n Badalona Spain Germans Trias i Pujol Research Institute c/Can Ruti s/n Badalona Spain Microbiology Department Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Department of Genetics and Microbiology Universitat Autònoma de Barcelona c/Can Ruti s/n Badalona Spain Faculty of Medicine University of Asyut El Fateh Assiut Governorate Egypt Department of Urology Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Canovelles Primary Health Care Unit Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Indústria Canovelles Spain Primary Health Care Unit Mataró-(Rocafonda-Palau) Barcelona North Metropolitan Health Directorate Catalan Institute for Health Camí Ral el Ravalet Mataró Barcelona Spain Barcelona North Metropolitan Primary Care Directorate Catalan Institute for Health Ctra. de Barcelona Sabadell Barcelona Spain Directorate for Innovation and Interdisciplinary Cooperation Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain IrsiCaixa-AIDS Research Institute Hospital Universitari Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Infectious Diseases Directorate Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain

Background Schistosomiasis is highly endemic in sub-Saharan Africa and frequently imported to europe. Male urogenital manifestations are often neglected. We aimed to ascertain the prevalence of genitourinary clinical signs and symptoms among long-term African migrants in a non-endemic european country using a serology *** We carried out a prospective, community-based cross-sectional study of adult male migrants from sub-Saharan Africa living in *** serology tests and microscopic urine examinations were carried out, and clinical data were obtained from an electronic medical record search and a structured *** We included 388 adult males, mean age 43.5 years [Standard Deviation (SD) = 12.0, range: 18–76]. The median time since migration to the european Union was 17 [Interquartile range (IQR): 11–21] years. The most frequent country of origin was Senegal (N = 179, 46.1%). Of the 338, 147 (37.6%) tested positive forSchistosoma. Parasite eggs were present in the urine of only 1.3%. Nine genitourinary clinical items were significantly associated with positiveSchistosoma serology results: pelvic pain (45.2%;OR = 1.57, 95%CI: 1.0–2.4), pain on ejaculation (14.5%;OR = 1.85, 95%CI: 1.0–3.5), dyspareunia (12.4%;OR = 2.45, 95%CI: 1.2–5.2), erectile dysfunction (9.5%;OR = 3.10, 95%CI: 1.3–7.6), self-reported episodes of infertility (32.1%;OR = 1.69, 95%CI: 1.0–2.8), haematuria (55.2%;OR = 2.37, 95%CI: 1.5–3.6), dysuria (52.1%;OR = 2.01, 95%CI: 1.3–3.1), undiagnosed syndromic STIs (5.4%), and orchitis (20.7%;OR = 1.81, 95%CI: 1.0–3.1). Clinical signs tended to *** Urogenital clinical signs and symptoms are prevalent among male African long-term migrants with a positiveSchistosoma serology results. Genital involvement can be frequent even among those with long periods of non-residence in their sub-Saharan African countries of origin. Further research is needed to develop diagnostic tools and validate therapeutic approaches to

关键词： Schistosomiasis Chronic schistosomiasis Urogenital schistosomiasis Male genital schistosomiasis Longterm migrant

Reversing gastric mucosal alterations during ethanol-induced chronic gastritis in rats by oral administration of Opuntia ficus-indica mucilage

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World Journal of Gastroenterology 2006年第27期12卷 4318-4324页

作者： Ricardo Vázquez-Ramírez Marisela Olguín-Martínez Carlos Kubli-Garfias Rolando Hernández-mu■oz Depto.de Biología Celular y Fisiología Instituto de Investigaciones Biomédicas. Universidad Nacional Autónoma de México. Apdo. Postal 70-243México D.F. 04510Mexico Depto.de Biología Celular Instituto de Fisiología Celular. Universidad Nacional Autónoma de México. Apdo. Postal 70-243México D.F. 04510Mxico Depto. de Biología Celular Institute de Fisiología Celular. Universidad Nacional Autónoma de México. Apdo. Postal 70-243México D.F. 04510Mxico

AIM： To study the effect of mucilage obtained from cladodes of Opuntia ficus-indica （Cactaceae） on the healing of ethanol-induced gastritis in rats. MeTHODS： Chronic gastric mucosa injury was treated with mucilage （5 mg/kg per day） after it was induced by ethanol. Lipid composition, activity of 5＇-nucleotidase （a membrane-associated ectoenzyme） and cytosolic activities of lactate and alcohol dehydrogenases in the plasma membrane of gastric mucosa were determined. Histological studies of gastric samples from the experimental groups were included. ReSULTS： ethanol elicited the histological profile of gastritis characterized by loss of the surface epithelium and infiltration of polymorphonuclear leukocytes. Phosphatidylcholine （PC） decreased and cholesterol content increased in plasma membranes of the gastric mucosa. In addition, cytosolic activity increased while the activity of alcohol dehydrogenases decreased. The administration of mucilage promptly corrected these enzymatic changes. In fact, mucilage readily accelerated restoration of the ethanol-induced histological alterations and the disturbances in plasma membranes of gastric mucosa, showing a univocal anti-inflammatory effect. The activity of 5＇-nucleotidase correlated with the changes in lipid composition and the fluidity of gastric mucosal plasma membranes. CONCLUSION： The beneficial action of mucilage seems correlated with stabilization of plasma membranes of damaged gastric mucosa. Molecular interactions between mucilage monosaccharides and membrane phospholipids, mainly PC and phosphatidylethanolamine （Pe）, may be the relevant features responsible for changing activities of membrane-attached proteins during the healing process after chronic gastric mucosal damage.

关键词： Gastritis mucilage Chronic gastric mucosal injury ethanol

The RNA binding proteins TIA1 and TIAL1 promote Mcl1 mRNA translation to protect germinal center responses from apoptosis

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Cellular & Molecular Immunology 2023年第9期20卷 1063-1076页

作者： Ines COsma-Garcia Mailys Mouysset Dunja Capitan-Sobrino Yann Aubert Martin Turner Manuel D.Diaz-muñoz Institute for Infectious and Inflammatory Diseases(INFINITy) Inserm UMR1291CNRS UMR5051University Paul SabatierCHU PurpanToulouse 31024France Immunology Program The Babraham InstituteCambridgeUK

Germinal centers(GCs)are essential for the establishment of long-lasting antibody *** B cells rely on post-transcriptional RNA mechanisms to translate activation-associated transcriptional programs into functional changes in the cell ***,the critical proteins driving these key mechanisms are still ***,we show that the RNA binding proteins TIA1 and TIAL1 are required for the generation of long-lasting GC ***1-and TIAL1-deficient GC B cells fail to undergo antigen-mediated positive selection,expansion and differentiation into B-cell clones producing high-affinity ***,TIA1 and TIAL1 control the transcriptional identity of dark-and light-zone GC B cells and enable timely expression of the prosurvival molecule ***,we demonstrate here that TIA1 and TIAL1 are key players in the post-transcriptional program that selects high-affinity antigen-specific GC B cells.

关键词： Adaptive immunity Germinal centers Post-transcriptional gene regulation RNA binding proteins Cell identity Apoptosis/10.1038/s41423-023-01063-4

Local recurrence of a parosteal osteosarcoma 21 years after incomplete resection

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Chinese Journal of Cancer 2011年第12期30卷 861-866页

作者： Andrés Combalia ernesto muoz-Mahamud Antonio Palacín Jaume Pomés Vicente López Department of Orthopaedic Surgery and Traumatology Orthopaedic Oncology Unit Hospital Clinic Faculty of Medicine University of Barcelona Barcelona 08036 Spain Department of Pathology Hospital Clinic Faculty of Medicine University of Barcelona Barcelona 08036 Spain Department of Radiology Hospital Clinic Faculty of Medicine University of Barcelona Barcelona 08036Spain

Parosteal osteosarcoma (POS) is the most common form of surface osteosarcoma. Its symptoms are insidious and its duration prior to diagnosis is considerably longer than that of other types of osteosarcoma. We report a case of POS with a growing mass but no evidence of metastasis. This tumor, which was diagnosed as calcified hematoma with benign characteristics, was incompletely resected in our hospital 21 years before the diagnosis of recurrence. The patient underwent a wide en bloc resection in our hospital and was free of symptoms, with no signs of tumor recurrence or metastasis during a 53-month follow-up.

关键词：骨肉瘤复发持续时间 POS 不完全诊断症状肿瘤

Computational algorithms for simulating the grain structure formed on steel billets using cellular automaton and chaos theories

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International Journal of Minerals,Metallurgy and Materials 2011年第1期18卷 24-34页

作者： A.Ramírez-López G.Soto-Cortés J.González-Trejo D.muoz-Negrón Department of Materials Metropolitan Autonomous University Institute Polytechnic National Institute Technologic Autonomous of Mexico

The development of some computational algorithms based on cellular automaton was described to simulate the structures formed during the solidification of steel *** algorithms described take results from the steel thermal behavior and heat removal previously calculated using a simulator developed by present authors in a previous *** time is used for displaying the steel transition from liquid to mushy and *** it is also used to command computational subroutines that reproduce nucleation and grain *** routines are logically programmed using the programming language C＋＋ and are based on a simultaneous solution of numerical methods （stochastic and deterministic） to create a graphical representation of different grain structures *** grain structure obtained is displayed on the computer screen using a graphical user interface （GUI）.The chaos theory and random generation numbers are included in the algorithms to simulate the heterogeneity of grain sizes and morphologies.

关键词： continuous casting solidification grain growth algorithms computer simulation