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Kuroshio Intrusion Combined with Coastal Currents Affects Phytoplankton in the Northern South China Sea Revealed by Lipid Biomarkers

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Journal of Ocean University of China 2023年第2期22卷 576-586页

作者： WANG Yaoyao BI Rong GAO Jiawei ZHANG Hailong LI Li DING Yang JIN Gui’e ZHAO Meixun Frontiers Science Center for Deep Ocean Multispheres and earth System and Key Laboratory of Marine Chemistry Theory and TechnologyMinistry of EducationOcean University of ChinaQingdao 266100China Laboratory for Marine ecology and environmental Science Qingdao National Laboratory for Marine Science and TechnologyQingdao 266237China

The northern South China Sea(NSCS)is significantly influenced by the Kuroshio intrusion and the coastal *** knowledge on the roles of both currents on phytoplankton spatial variations is still ***,we investigated the concentrations of phytoplankton biomarkers and their proportions in surface suspended particles from 47 sites of the NSCS during summer of 2017 and ***/epi-brassicasterol,dinosterol,and C37 alkenones were used as proxies of biomass for diatoms,dinoflagellates,and haptophytes,respectively,and their sum indicating total phytoplankton biomass.A three end-member mixing model was applied to quantitatively assess the influence extent of the Kuroshio intrusion and the coastal *** results showed that the Kuroshio intrusion and the coastal currents contributed equally to the overall surface water masses in the study area;however,the two currents had distinct effects on the spatial distribution of *** phytoplankton biomass,the eutrophic coastal currents were likely to be the main controlling factors,while the impact of the Kuroshio intrusion was weak and stimulated significant increases in phytoplankton biomass only at certain boundary *** phytoplankton community structures,the Kuroshio and its intrusion were the main factors,resulting in an increase in the proportions of dinoflagellates and *** proportion of diatoms slightly increased due to the influence of the coastal *** study quantifies the effects of the Kuroshio and the coastal currents on phytoplankton in the NSCS in terms of hydrological parameters,providing an important basis for the understanding of ecological functions and biogeochemical cycles in marginal sea-open ocean boundary regions.

关键词： sterols alkenones phytoplankton northern South China Sea Kuroshio coastal currents

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What to eat:evidence for Selective Autophagy in Plants

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Journal of Integrative Plant Biology 2012年第11期54卷 907-920页

作者： Brice e.Floyd Stephanie C.Morriss Gustavo C.MacIntosh Diane C.Bassham Department of Genetics Development and Cell BiologyIowa State UniversityAmes IA 50011USA Department of Biochemistry Biophysics and Molecular BiologyIowa State UniversityAmes IAUSA

Autophagy is a macromolecular degradation pathway by which cells recycle their contents as a developmental process, housekeeping mechanism, and response to environmental stress. In plants, autophagy involves the sequestration of cargo to be degraded, transport to the cell vacuole in a doublemembrane bound autophagosome, and subsequent degradation by lytic enzymes.

关键词： Autophagy degradation stress vacuole.

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empirical pairing gaps and neutron-proton correlations

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Chinese Physics C 2019年第1期43卷 109-121页

作者： B.S.Ishkhanov S.V.Sidorov T.Yu.Tretyakova e.V.Vladimirova Faculty of Physics Lomonosov Moscow State University Skobeltzyn Institute of Nuclear Physics Lomonosov Moscow State University

Analysis of various mass formulas related to neutron-proton correlations in atomic nuclei is carried *** the example of the N =Z chain it is shown that for self-adjoint nuclei various formulas proposed in literature for estimating the np pairing energy lead to similar results. Significant differences between the calculation methods arise when nuclei with N = Z are considered, which allows to reveal the complexity of neutron-proton correlations in different types of atomic nuclei and to make assumptions on the correspondence of the mass relation to the real effect of np pairing. The Shell Model parametrization of the binding energy makes it possible to draw additional conclusions on the structure of mass formulas and their relationship.

关键词： nucleon interaction models of atomic nuclei nucleon pairing in atomic nuclei

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Function and regulation of self-reactive marginal zone B cells in autoimmune arthritis

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Cellular & Molecular Immunology 2015年第4期12卷 493-503页

作者： Anna-Karin e Palm Heike C Friedrich Anja Mezger Maya Salomonsson Linda K Myers Sandra Kleinau Department of Cell and Molecular Biology Uppsala University Uppsala Sweden Department of Pediatrics University of Tennessee Health ScienceCenter Memphis TN USA

Polyreactive innate-type B cells account for many B cells expressing self-reactivity in the periphery. Improper regulation of these B cells may be an important factor that underlies autoimmune disease. Here we have explored the influence of self-reactive innate B cells in the development of collagen-induced arthritis （CIA）, a mouse model of rheumatoid arthritis. We show that splenic marginal zone （MZ）, but not B- 1 B cells exhibit spontaneous IgM reactivity to autologous collagen II in na＇=＇ve mice. Upon immunization with heterologous collagen II in complete Freund＇s adjuvant the collagen-reactive MZ B cells expanded rapidly, while the B-1 B cells showed a modest anti-collagen response. The MZ B cells were easily activated by toll-like receptor （TLR） 4 and 9-1igands in vitro, inducing proliferation and cytokine secretion, implying that dual engagement of the B-cell receptor and TLRs may promote the immune response to self-antigen. Furthermore, collagen-primed MZ B cells showed significant antigen-presenting capacity as reflected by cognate T-cell proliferation in vitroand induction of IgG anti-collagen antibodies in vivo. MZ B cells that were deficient in complement receptors I and 2 demonstrated increased proliferation and cytokine production, while Fcy receptor lib deficiency of the cells lead to increased cytokine production and antigen presentation. In conclusion, our data highlight self-reactive MZ B cells as initiators of the autoimmune response in CIA, where complement and Fc receptors are relevant in controlling the self-reactivity in the cells.

关键词： arthritis complement receptors Fc receptors marginal zone B cells, mice

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Y-chromosomal microdeletions and partial deletions of the Azoospermia Factor c(AZFc)region in normozoospermic,severe oligozoospermic and azoospermic men in Sri Lanka

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Asian Journal of Andrology 2006年第1期8卷 39-44页

作者： L.Fernando J.Gromoll T.R.Weerasooriya e.Nieschlag M.Simoni Institute of Reproductive Medicine of the University Münster University HospitalD-48129 MünsterGermany Reproductive Biology LaboratoryFaculty of MedicineKarapitiyaGalleSri Lanka Institute of Reproductive Medicine of the University Münster University HospitalD-48129 MünsterGermany Reproductive Biology Laboratory Faculty of MedicineKarapitiyaGalleSri Lanka

Aim： To assess for the first time the occurrence of Y chromosomal microdeletions and partial deletions of the Azoospermia Factor c （AZFc） region in Sri Lankan men and to correlate them with clinical parameters. Methods： In a retrospective study, we analyzed 96 infertile men （78 with non-obstructive azoospermia） and 87 controls with normal spermatogenesis. AZFa, AZFb, AZFc and partial deletions within the AZFc region were analyzed by multiplex polymerase chain reaction （PCR） according to established protocols. Results： No AZFa, AZFb or AZFc deletions were found in the control group. Seven patients in the group of infertile men were found to have deletions as following： one AZFa, two AZFc, two AZFbc and two AZFabc. The relative distribution of these patterns was significantly different compared with that found in the German population. extension analysis confirmed that the deletions occurred according to the current pathogenic model, gr/gr deletions were found to be equally present both in the patients （n = 4） and in the control group （n = 4）. One b2/b3 deletion was found in the patient group. Conclusion： These results suggest that the frequency and pattern of microdeletions of the Y chromosome in Sri Lankan men are similar to those found in other populations and confirm that gr/gr deletions are not sufficient to cause spermatogenetic failure. （Asian J Androl 2006 Jan; 8： 39-44）

关键词： Y chromosome male infertility gr/gr b2/b3 microdeletion normozoospermia azoospermia factor c

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CONDUCTIVe COMPOSITeS FROM POLYPYRROLe eLeCTROPOLYMeRIZeD IN A POLYUReTHANe MATRIX

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Chinese Journal of Polymer Science 1990年第2期8卷 149-157页

作者：宝净生 M. L. DAROUX M. LITT e. B. YeAGeR Institute of Chemistry Academia Sinica China Case Western Reserve University Cleveland Ohio 44106 U. S. A.

In order to improve the mechanical properties of polypyrrole, composites were made by electropolymerizing polypyrrole in a polyurethane matrix. Polypyrrole/polyurethane (PPY/PU) composite films containing CLO_4^-, BF_4^- or CH_3-C_6H_4-SO_3^- counter ions were made in a variety of solvent systems and characterized by SeM, electronic conductivity, FTIR, and mechanical properties. Composite films showing much greater fiexibility than pure polypyrrole were obtained, but their electronic conductivities were substantially lower. Measured eonductivities ranged from 0.001 to 8 S/cm, tensile strengths from 44 to 592 psi, and elongation to failure from 3 to 70%.

关键词： eG NB PP CONDUCTIVe COMPOSITeS FROM POLYPYRROLe eLeCTROPOLYMeRIZeD IN A POLYUReTHANe MATRIX IM ACN THF

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凉山州某县未接受抗病毒治疗的HIV-1感染者的耐药情况分析

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中国感染与化疗杂志 2024年第1期24卷 19-24页

作者：刘梅朱芮吴涛俄尔阿沙木袁天茹宋绍芳刘玲梁洪远曹汴川越西县第一人民医院抗病毒治疗中心四川凉山616650 首都医科大学附属北京地坛医院艾滋病临床中心西南医科大学附属医院感染病科结核病科感染与免疫实验室

目的分析凉山州某县未接受抗病毒治疗的HIV-1感染者的传播性耐药(TDR)情况,为了解当地HIV-1耐药株的传播及抗反转录病毒治疗(ART)方案的制定提供理论依据和技术支撑。方法以来源于2022年1—8月在凉山州某县未接受ART的HIV-1感染者为研... 详细信息

目的分析凉山州某县未接受抗病毒治疗的HIV-1感染者的传播性耐药(TDR)情况,为了解当地HIV-1耐药株的传播及抗反转录病毒治疗(ART)方案的制定提供理论依据和技术支撑。方法以来源于2022年1—8月在凉山州某县未接受ART的HIV-1感染者为研究对象,采集其血液样本并分离血浆和血细胞,血浆样本用于HIV-1 RNA定量检测和HIV-1 RNA基因型耐药检测,血细胞样本用于HIV-1 DNA定量检测和HIV-1 DNA基因型耐药检测。结果135例研究对象中,男性75例(55.6%),女性60例(44.4%),中位年龄37.5岁,彝族占比最大(96.3%)。性途径传播为HIV-1主要传播方式(83.0%)。发生TDR的有11例,发生率为8.1%。诊断HIV-1感染距耐药检测时间的中位数为11 d。HIV-1 RNA以10001~100000拷贝/mL占比较多(43.7%)。HIV-1 DNA以101~1000拷贝/106 cells占比较多(55.6%)。HIV-1亚型中,以B+C亚型重组占比最高(51.9%),其次为CRF07_BC重组型(43.0%)。135例研究对象中,有23例(17.0%)出现耐药突变位点,与非核苷类反转录酶抑制剂(NNRTI)有关的耐药突变位点有16例(11.9%),K103N是主要的耐药突变位点,依非韦伦和奈韦拉平是主要的耐药药物;与整合酶抑制剂(INSTI)有关的耐药突变位点有6例(4.4%),e157Q是主要的耐药突变位点,埃替拉韦和拉替拉韦是主要的耐药药物;有1例(0.7%)同时出现NNRTI和INSTI耐药突变位点。经过单因素和多因素logistic回归分析,相较于年龄>30岁,年龄≤30岁发生TDR风险更高。结论凉山州某县未接受ART的HIV-1感染者的耐药情况不容忽视,相较于年龄>30岁,年龄≤30岁发生TDR风险更高,建议HIV-1感染者在接受ART前均进行HIV-1耐药检测。

关键词：耐药突变位点传播性耐药人类免疫缺陷病毒抗反转录病毒治疗

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Photoacoustic detection of circulating melanoma cells in late stage patients

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Journal of Innovative Optical Health Sciences 2020年第6期3卷 47-54页

作者： John A.Viator Marc Hazur Andrea Sajewski Ahmad Tarhini Martin e.Sanders Robert H.edgar Department of engineering Duquesne University 600 Forbes Avenue PittsburghPennsylvania 15282USA Department of Bioengineering University of Pittsburgh 3700 O'Hara Street PittsburghPA 15260USA Moffitt Comprehensive Cancer Center and Research Institute 10920 McKinley Drive TampaFlorida 33612USA Acousys Biodevices Inc 1777 Highland Drive Ann ArborMichigan 48108USA

Melanoma is the deadliest skin cancer and is responsible for over 7000 deaths in the US *** spread of cancer,or metastasis,is responsible for these deaths,as secondary tumors interrupt normal organ *** tumor cells,or those cells that spread throughout the body from the primary tumor,are thought to be responsible for *** developed an optical method,photoacoustic flow cytometry,in order to detect and enumerate circulating melanoma cells(CMCs)from blood samples of *** tested the blood of StageⅣmelanoma patients to show the ability of the photoacoustic flow cytometer to detect these rare cells in *** then tested the system on archived blood samples from StageⅢmelanoma patients with known outcomes to determine if detection of CMCs can predict future *** detected between 0 and 66 CMCs in StageⅣ*** the StageⅢstudy,we found that of those samples with CMCs,two remained disease free and five developed *** those without CMCs,six remained disease free and one developed *** believe that photoacoustic detection of CMCs provides valuable information for the prediction of metastasis and we postulate a system for more accurate prognosis.

关键词： Diagnosis metastasis optoacoustics

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effect of Hydrolyzing Agents on the Properties of Poly(ethylene Glycol)-Fe_3O_4 Nanocomposite

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Nano-Micro Letters 2011年第2期3卷 79-85页

作者： e.Karaoglu H.Kavas A.Baykal M.S.Toprak H.Szeri Department of Chemistry~b Fatih University Department of Physics Gebze Institute of Technology Functional Materials Division Royal Institute of Technology-KTH TUBITAK-UMe National Metrology Institute

Poly(ethylene glycol)(PeG) assisted hydrothermal route has been used to study the influence of the hydrolyzing agent on the properties of PeG-iron oxide(Fe_3O_4) *** oxide nanoparticles(NPs),as confirmed by X-ray diffraction analysis,have been synthesized by a hydrothermal method in which Na OH and NH_3 were used as hydrolyzing *** of PeG-Fe_3O_4 nanocomposite was confirmed by Fourier transform infrared spectroscopy(FTIR).Samples exhibit different crystallite sizes,which estimated based on line profile fitting as 10 nm for NH_3 and 8 nm for Na OH hydrolyzed *** average particle sizes obtained from transmission electron microscopy was respectively 174±3 nm for Na OH and 165±4 nm for NH3 gas hydrolyzed *** characterization results reveal superparamagnetic characteristics despite a large particle size,which indicate the absence of coupling between the nanocrystals due to the presence of polymer in the *** conductivity curve demonstrates that σDC is strongly temperature dependent.

关键词： Magnetite PeG Hydrothermal synthesis Conductivity Magnetization

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enhanced biological wastewater treatment using sodium alginate-immobilized microorganisms in a fluidized bed reactor

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Water Science and engineering 2022年第2期15卷 125-133页

作者： Yaneth A.Bustos-Terrones erick R.Bandala Gabriela e.Moeller-Chávez Victoria Bustos-Terrones Division of Graduate Studies and Research CONACYT-TecNM-Technological Institute of CuliacánCuliacánSinaloa 80220Mexico Division of Hydrologic Sciences Desert Research InstituteLas VegasNV 89119-7363USA Academic Direction of environmental Technology engineering Polytechnic University of the State of MorelosJiutepecMorelos 62550Mexico

In this study,a microbial consortium isolated from an activated sludge tank of a conventional wastewater treatment plant was immobilized using sodium alginate(SA)as a support material for contaminant biodegradation in wastewater.A volume of 500 mL of activated sludge was immobilized in the SA beads(with a mass concentration of 25 g/L).The resulting SA beads were characterized,introduced into a fluidized bed reactor,fed with 1000 mL of the sample,and characterized again after the treatment *** SA-immobilized microorganisms were tested first for degradation of organic matter(expressed as chemical oxygen demand)and total phosphorous in domestic wastewater,achieving removal efficiencies of 71%and 93%,respectively,after 12 ***,the SA-immobilized microorganisms were tested for degradation of a basic blue 9(BB9)textile dye in a condition that simulated textile *** efficiency of the BB9 degradation was found to be as high as 99.5%after 2 *** to these results,SA-immobilized microorganisms were found to be an environmentally friendly and cost-effective alternative for treatment of municipal and industrial wastewater effluents.

关键词： Domestic wastewater Basic blue 9 Immobilized microorganisms Fluidized bed reactor Sodium alginate

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