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Stabilization of a high-order harmonic generation seeded extreme ultraviolet free electron laser by time-synchronization control with electro-optic sampling

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High Power Laser Science and engineering 2015年第2期3卷 1-10页

作者： H.Tomizawa T.Sato K.Ogawa K.Togawa T.Tanaka T.Hara M.Yabashi H.Tanaka T.Ishikawa T.Togashi S.Matsubara Y.Okayasu T.Watanabe e.j.takahashi K.Midorikawa M.Aoyama K.Yamakawa S.Owada A.Iwasaki K.Yamanouchi RIKeN SPring-8 Center japan Synchrotron Radiation Research Institute RIKeN Center for Advanced Photonics japan Atomic energy Agency The University of Tokyo

A fully coherent free electron laser(FeL) seeded with a higher-order harmonic(HH) pulse from high-order harmonic generation(HHG) is successfully operated for a sufficiently prolonged time in pilot user experiments by using a timing drift feedback. For HHG-seeded FeLs, the seeding laser pulses have to be synchronized with electron bunches. Despite seeded FeLs being non-chaotic light sources in principle, external laser-seeded FeLs are often unstable in practice because of a timing jitter and a drift between the seeding laser pulses and the accelerated electron bunches. Accordingly,we constructed a relative arrival-timing monitor based on non-invasive electro-optic sampling(eOS). The eOS monitor made uninterrupted shot-to-shot monitoring possible even during the seeded FeL operation. The eOS system was then used for arrival-timing feedback with an adjustability of 100 fs for continual operation of the HHG-seeded FeL. Using the eOS-based beam drift controlling system, the HHG-seeded FeL was operated over half a day with an effective hit rate of 20%–30%. The output pulse energy was 20 μj at the 61.2 nm wavelength. Towards seeded FeLs in the water window region, we investigated our upgrade plan to seed high-power FeLs with HH photon energy of 30–100 e V and lase at shorter wavelengths of up to 2 nm through high-gain harmonic generation(HGHG) at the energy-upgraded SPring-8Compact SASe Source(SCSS) accelerator. We studied a benefit as well as the feasibility of the next HHG-seeded FeL machine with single-stage HGHG with tunability of a lasing wavelength.

关键词： arrival-timing monitor electro-optic sampling(eOS)

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NeCAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael K.e.Schafer Sudena Wang Michael j.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding proteins 1–3(NeCAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one eF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NeCAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NeCAB2 interacts with predominantly striatal G-protein-coupled receptors, while NeCAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NeCAB proteins exhibit distinct subcellular localizations: NeCAB1 is found in the nucleus and cytosol, NeCAB2 resides in endosomes and the plasma membrane, and NeCAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NeCAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NeCAB proteins by controlling the availability of protein–protein interaction domains situated between the eF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

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Creep and creep-fatigue behavior of high chromium steel weldment

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Acta Metallurgica Sinica(english Letters) 2011年第3期24卷 175-182页

作者： Yukio takahashi Masaaki TABUCHI Materials Science Laboratory Central Research Institute of Electric Power Industry National Institute of Material Sciences

Strength of welded joints of high chromium steels is one of the important concerns for fabricators and operators of ultra supercritical thermal power plants. A number of creep as well as creep-fatigue tests with tensile hold have been carried out on the welded joints of two types of high chromium steels widely used in japan, i.e. Grade 91 and 122 steels. It was found that failure occurred in fine grain heat-affected zone in all the creep-fatigue tests, even at a relatively low temperature and fairly short time where failure occurred in plain base metal region in simple creep testing. Four procedures were used to predict failure lives and their results were compared with the test results. A newly proposed energy-based approach gave the best estimation of failure life, without respect of the material and temperature.

关键词： Creep Creep-fatigue High chromium steel Life prediction Welded joint

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Hybrid silicon modulators

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Chinese Optics Letters 2009年第4期7卷 280-285页

作者： j.e.Bowers Department of electrical and Computer engineering University of California Santa Barbara

A number of active elements have been demonstrated using the hybrid silicon evanescent platform, including lasers, amplifiers, and detectors. In this letter, two types of hybrid silicon modulators, flflfilling the building blocks in optical communication on this platform, are presented. A hybrid silicon electroabsorp- tion modulator, suitable for high speed interconnects, with 10-dB extinction ratio at -5 V and 16-GHz modulation bandwidth is demonstrated. In addition, a hybrid silicon Mach-Zehnder modulator utilizing carrier depletion in multiple quantum wells is proved with 2 *** voltage-length product, 150-nm optical bandwidth, and a large signal modulation up to 10 Gb/s.

关键词： Bandwidth electroabsorption modulators Modulation Modulators Optical communication Quantum well lasers Semiconducting indium compounds Semiconductor quantum wells Silicon Silicon detectors

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Approximate ballistics formulas for spherical pellets in free flight

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Defence Technology（防务技术） 2018年第1期14卷 1-11页

作者： e.j.Allen Department of Mathematics and Statistics Texas Tech University

The ballistics equations for spherical pellets in free flight are simplified through appropriate scaling of the pellet velocity and pellet distance. Two different drag coefficient curves are averaged to yield a single curve applicable to shot pellets and round balls. The resulting S-shaped drag coefficient curve is approximated by three straight-line segments. The scaled ballistics equations are then solved exactly and simple formulas are found for the velocity and flight time with respect to trajectory distance. The formulas are applicable to spherical shot pellets and round balls of any composition under any atmospheric conditions. The formulas are amenable to quick and easy computation and may also serve as an aid in understanding and comparing black-box ballistics calculators. For shotshell ballistics, an important assumption in the present investigation is that the pellets are moving as single, free spheres and not as a dense cloud or in a shot column, in particular, the pellets are not interacting during flight. Therefore, the formulas are most appropriate for single round balls, for large shot sizes, and for pellets of small shot size fired from open chokes. The formulas are clear and accessible, and can be implemented by military or law enforcement personnel as well as hunters and shooters. This work differs from previous investigations in that accurate ballistics formulas are derived for spherical projectiles of shotguns and muzzleloaders using realistic drag coefficients.

关键词： Ballistics Sphere Drag Shotgun Muzzleloader Nondimensionalization

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Challenges for beyond 5G:ultra-densification of radio access network

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通信学报 2020年第11期41卷 1-11页

作者： Fumiyuki Adachi Ryo takahashi Hidenori Matsuo Research Organization of electrical Communication Tohoku UniversitySendai 980-8577Japan

Ultra-densification of radio access network(RAN)is a key to efficiently support the exponentially growing mobile data traffic in 5 G ***,extremely high frequency band like mm Wave band was utilized to solve the bandwidth shortage ***,untra-dense reusing the same radio resource produced severe *** the mm Wave link was very harsh due to frequent blockage by *** a new RAN architecture needed to be introduced to realize ultra-reliable communications in such a severe radio propagation *** architecture of distributed MIMO based RAN was ***,enhanced interference coordination(e IC)was ***,the effectiveness of distributed MIMO based RAN with e IC by computer simulation was showed.

关键词： 5G advanced systems distributed MIMO radio access network interference coordination cooperative signal transmission

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Are hydrides under high-pressure-high-temperature superconductors?

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National Science Review 2024年第7期11卷 9-12页

作者： j.e.Hirsch Department of Physics University of California

Contrary to the current consensus, I argue that the existing evidence for high-temperature superconductivity in hydrides under high pressure is not compelling. I suggest that the focus of the field should urgently shift to establish unequivocally experimentally whether or not superconductivity in pressurized hydrides exists, instead of continuing to search for new materials that might show elusive signals of unproven superconductivity at ever higher temperatures. The implications of a negative finding for the theoretical understanding of superconductivity are discussed.

关键词： Hydrides

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On a New Geometric Constant Related to the Modulus of Smoothness of a Banach Space

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Acta Mathematica Sinica,english Series 2014年第9期30卷 1526-1538页

作者： Yasuji takahashi Mikio KATO Department of System engineering Okayama Prefectural University Department of Mathematics Faculty of EngineeringShinshu University

We shall introduce a new geometric constant A（X） of a Banach space X, which is closely related to the modulus of smoothness px （T）, and investigate it in relation with the constant As （X） by Baronti et al., the von Neumann-jordan constant CNj（X） and the james constant j（X）. A sequence of recent results on these constants as well as some other geometric constants will be strengthened and improved.

关键词： Constant A(X) von Neumann-jordan constant james constant modulus of smoothness modulus of convexity uniform non-squareness

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interleukin 28B genetic polymorphism and hepatitis B virus infection

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World journal of Gastroenterology 2014年第34期20卷 12026-12030页

作者： Toru takahashi Division of Gastroenterology and Hepatology Uonuma HospitalOjiyashiNiigata 947-0028Japan

Interleukin (IL) 28B genetic polymorphism is significantly associated with the sustained virological response rate in patients with chronic hepatitis C treated with pegylated interferon-α (PeG-IFN) plus ribavirin and with spontaneous hepatitis C virus clearance. However, a consensus on the relationship between IL28B genetic polymorphism and the favorable outcome of chronic hepatitis B virus infection defined by hepatitis B e antigen seroconversion, and/or hepatitis B surface antigen seroclearance in patients treated with interferon or PeG-IFN has not been reached. Several reports failed to show a positive association, while some studies demonstrated a positive association in certain subject settings. More prospective studies including large cohorts are needed to determine the possible association between IL28B genetic polymorphism and the outcome of interferon or PeG-IFN treatment for chronic hepatitis B.

关键词： interleukin 28B Polymorphism Hepatitis B virus interferon Pegylated interferon

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Urban climate in the Tokyo metropolitan area in japan

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journal of environmental Sciences 2017年第9期29卷 54-62页

作者： jun Matsumoto Fumiaki Fujibe Hideo takahashi Research Center for Climatology Department of Geography Tokyo Metropolitan University Department of Coupled Ocean-Atmosphere-Land Processes Research JAMSTEC

Long-term climate changes related with urbanization in Tokyo, japan, and recent temperature and heavy rainfall distribution in the Tokyo metropolitan area are reviewed. A relatively high temperature increase in annual mean temperature at the rate of 3.0°C/century was detected in Tokyo for the period 1901–2015. Some observational evidence showed the existence of both thermal and mechanical effects of urbanization on recent heavy rainfall occurrences, and modeling studies also support precipitation enhancement. Urban influences were recognized in other climatological elements, such as number of fog days, relative humidity, and wind circulation.

关键词： Heat island Cool island Heavy rainfall Fog Humidity Sea breeze

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