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Can training extend current guidelines for cochlear implant candidacy?

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Neural Regeneration Research 2015年第5期10卷 718-720页

作者： Amal Isaiah Douglas e.h.hartley Department of Otorhinolaryngology-head and Neck Surgery University of Maryland School of Medicine National Institute for health Research (NIhR) Nottingham Hearing Biomedical Research Unit Otology and hearing Group Division of Clinical NeuroscienceSchool of MedicineUniversity of Nottingham Medical Research Council (MRC) Institute of hearing Research

Since their introduction in the 1960s, cochlear implants （CIS） have undergone several transformations, ulti- mately positioning themselves as the best-performing neural prosthesis available today. They have also been recognized as a unique tool for studying the potential protective effects of patterned electrical stimulation on the developing auditory system, with results from animal models often changing the manner in which CIs are used clinically to deliver auditory information to the brain （Moore and Shannon, 2009）. From the development of the first successful commercial single-channel device, they have evolved into multi-channel devices that are part of the national health programmes of several coun- tries. From the limited speech information provided by the early, rudimentary cochlear implants, these devices are now in a position to deliver intelligible speech infor- mation to the auditory system, largely due to advances in signal processing. Concerted efforts from several dis- ciplines, including engineering, acoustics, neurobiology and otolaryngology have ensured that the continued development of CI technology has resulted in signifi- cant benefits to individuals with profound sensorineural hearing loss.

关键词： Can training extend current guidelines for cochlear implant candidacy CI

Cytochrome P450 levels are altered in patients with esophageal squamous-cell carcinoma

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World Journal of Gastroenterology 2007年第7期13卷 997-1002页

作者： I Bergheim e Wolfgarten e Bollschweiler Ah hlscher C Bode A Parlesak Department of Physiology of Nutrition Hohenheim University (140e) Stuttgart 70599 Germany Department of Visceral and Vascular Surgery University of Cologne Cologne Germany

AIM： To investigate the role of cytochrome P450 （CYP） in the carcinogenesis of squamous-cell carcinoma （SCC） in human esophagus by determining expression patterns and protein levels of representative CYPs in esophageal tissue of patients with SCC and controls. MeThODS： mRNA expression of CYP2e1, CYP2C, CYP3A4, and CYP3A5 was determined using RT-PCR in both normal and malignant esophageal tissues of patients with untreated esophageal SCC （/7 = 21） and in controls （n = 10）. Protein levels of CYP2e1, CYP2CS, CYP3A4, and CYP3A5 were measured by Western blot. ReSULTS： Within the group of SCC patients, mRNA expression of CYP 3A4 and CYP2C was significantly lower in malignant tissue （-39% and -74%, respectively, P 〈 0.05） than in normal tissue. Similar results were found in CYP3A4 protein levels. Between groups, CYP3A4, CYP3A5, and CYP2C8 protein concentration was significantly higher in non-malignant tissue of SCC patients （4.8-, 2.9-, and 1.9-fold elevation, P 〈 0.05） than in controls. In contrast, CYP2e1 protein levels were significantly higher in controls than in SCC patients （＋46%, P 〈 0.05）. CONCLUSION： Significant differences exist in protein levels of certain CYPs in non-malignant esophageal tissue （e.g. CYP2CB, CYP3A4, CYP3A5, and CYP2e1） between SCC patients and healthy subjects and may contribute to the development of SCC in the esophagus.

关键词： Squamous-cell carcinoma Cytochrome P450 Western blot RT-PCR human

Arbitrary-state solutions of the Dirac equation for a Mbius square potential using the Nikiforov-Uvarov method

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Chinese Physics C 2013年第4期37卷 26-35页

作者： e.Maghsoodi h.hassanabadi h.Rahimov S.Zarrinkamar Physics Department Shahrood University of Technology Computer engineering Department Shahrood University of Technology Department of Basic Sciences Garmsar BranchIslamic Azad University

We inquire into spin and pseudospin symmetries of the Dirac equation under a Mbius square-type potential using the Nikiforov-Uvarov method to calculate the bound state solutions. We numerically discuss the problem a... 详细信息

关键词： Dirac equation spin symmetry pseudospin symmetry Mobius potential

An angle-dependent potential and alpha-decay half-lives of deformed nuclei for 67≤Z≤91

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Chinese Physics C 2013年第4期37卷 43-50页

作者： h.hassanabadi e.Javadimanesh S.Zarrinkamar h.Rahimov Physics Department Shahrood University of Technology Department of Basic Science Garmsar BranchIslamic Azad University Computer engineering Department Shahrood University of Technology

The half-lives of deformed nuclei are reported for 67≤Z≤91. We consider an angle-dependent potential which yields multiple approximations. The results are in better agreement with the experimental data when the mult... 详细信息

关键词： alpha decay deformed nuclei ground state multiple approximation

The radial evolution of earthward BBFs during substorm

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Science China earth Sciences 2010年第10期53卷 1542-1551页

作者： ReMe h DANDOURAS I LUCeK e DUNLOP M Centre d'etude Spatiale des Rayonnements Blackett Laboratory Imperial College London Rutherford Appleton Laboratory

We here study the occurrence rate,probability function of velocity and duration of earthward bursty bulk flows(BBFs) in the Inner Plasma Sheet(IPS,β>0.5) using the data of Cluster in 2001 and *** occurrence rate of earthward BBFs increases with distance from the earth up to ?19 Re,which is in agreement with the previous observations of the radial evolution of *** 54% of earthward BBFs in expansion phase have a velocity larger than 600 km/s,whereas only 38% of earthward BBFs in growth and recovery phases have a velocity larger than 600 km/*** average velocity of earthward BBFs in expansion phase is 732 km/s,larger than those in growth phase(631 km/s) and recovery phase(617 km/s).The durations of earthward BBFs decrease with the decrease of downtail distance from earth due to the braking of earthward *** duration of earthward BBFs in expansion phase is larger than that in growth and recovery *** average durations in growth,expansion,and recovery phases are respectively 49.3,71.5,and 47.6 ***,the ratios of transports of energy of earthward BBFs in growth,expansion,and recovery phases can be estimated to be 0.51:1:***,the earthward BBFs in the expansion phase have the largest capability of the transport of energy and can produce the largest braking effects,such as inertial currents and auroral activities.

关键词： substorm growth expansion recovery duration energy transport

Predictability of US tornado outbreak seasons using eNSO and northern hemisphere geopotential height variability

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Geoscience Frontiers 2016年第1期7卷 21-31页

作者： Kent h.Sparrow Andrew e.Mercer Department of Geosciences Mississippi State University

The predictability of dangerous atmospheric phenomena such as tornado outbreaks has generally been limited to a week or less. however, recent work has demonstrated the importance of the Rossby wavetrain phasing over the United States in establishing outbreak-favorable environments. The predictability of Rossby wavetrain phasing is strongly related to numerous climate-scale interannual variability indices, which are predictable many months in advance. To formalize the relationship between interannual variability indices and seasonal tornado outbreak frequency, indices derived from monthly mean Northern hemisphere 500-hPa and 1000-hPa geopotential height fields and Ni？o 3.4 indices for eNSO phase were compared to annual tornado outbreak seasonal frequencies. Statistical models predicting seasonal outbreak frequency were established using linear（stepwise multivariate linear regressione SMLR） and nonlinear（support vector regressione SVR） statistical modeling *** stepwise methodology revealed predictors that are important in establishing outbreak-favorable environments at long lead times. Additionally, the results of the statistical modeling revealed that the nonlinear SVR technique reduced root mean square errors produced by the control SMLR technique by 28% and provided more consistent forecasts. A preliminary physical analysis revealed that years with high outbreak frequencies were associated with the presence of 500-mb troughs over the central and western US during the peak of outbreak season, while lower frequencies were consistent with ridging over the US or northwest flow over the Plains. These patterns support the results of the statistical modeling, which demonstrate the utility of geopotential height variability as a predictability measure of outbreak frequency.

关键词： Interannual variability Support vector regression Climate predictability Tornado outbreaks

A high performance gas–liquid two-phase flow meter based on gamma-ray attenuation and scattering

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Nuclear Science and Techniques 2017年第11期28卷 271-279页

作者： G. h. Roshani e. Nazemi electrical engineering Department Kermanshah University of Technology Kermanshah Iran Nuclear Science and Technology Research Institute TehranIran Radiation Application Department Shahid Beheshti University Tehran Iran

The ability to precisely estimate the void fraction of multiphase flow in a pipe is very important in the petroleum industry. In this paper, an approach based on our previous works is proposed for predicting the void fraction independent of flow regime and liquid phase density changes in gas–liquid two-phase flows. Implemented technique is a combination of dual modality densitometry and multi-beam gamma-ray attenuation techniques. The detection system is comprised of a single energy fan beam,two transmission detectors, and one scattering detector. In this work, artificial neural network(ANN) was also implemented to predict the void fraction percentage independent of the flow regime and liquid phase density changes. Registered counts in three detectors and void fraction percentage were utilized as the inputs and output of ANN, respectively. By applying the proposed methodology, the void fraction was estimated with a mean relative error of less than just 1.2480%.

关键词： Gamma-ray Transmission and scattering Artificial neural network Density independent Flow regime independent Void fraction

effects of Crossed electric and Magnetic Fields on Shallow Donor Impurity Binding energy in a Parabolic Quantum Well

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Chinese Physics Letters 2004年第12期21卷 2500-2503页

作者： e.Kasapoglu h.Sari I.Soekmen DepartmentofPhysics CumhuriyetUniversity58140SivasTurkey DepartmentofPhysics DokuzEylülUniversityIzmirTurkey

We have calculated variationally the ground state binding energy of a hydrogenic donor impurity in a parabolic quantum well in the presence of crossed electric and magnetic fields. These homogeneous crossed fields are such that the magnetic field is parallel to the heterostructure layers and the electric field is applied perpendicular to the magnetic field. The dependence of the donor impurity binding energy to the well width and the strength of the electric and magnetic fields are discussed. We hope that the obtained results will provide important improvements in device applications, especially for a suitable choice of both fields in the narrow well widths.

关键词： Binding energy

exact solutions of the Dirac equation with Pschl-Teller double-ring-shaped Coulomb potential via the Nikiforov-Uvarov method

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Chinese Physics B 2013年第3期22卷 117-121页

作者： e.Maghsoodi h.hassanabadi S.Zarrinkamar Physics Department Shahrood University of TechnologyShahroodIran Department of Basic Sciences Garmsar BranchIslamic Azad UniversityGarmsarIran

exact analytical solutions of the Dirac equation are reported for the Poschl-Teller double-ring-shaped Coulomb *** radial,polar,and azimuthal parts of the Dirac equation are solved using the Nikiforov-Uvarov method,an... 详细信息

关键词： Dirac equation Poschl-Teller double-ring-shaped Coulomb potential Nikiforov-Uvarov method