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国际医学放射学杂志 2024年第4期 500-501页

作者： D.J.van der Reijd C.guerendel F.C.R.Staal M.P.Busard M.de Oliveira Taveira e.g.klompenhouwer 刘晓彤

摘要目的对3种既往报道的基于CT预测结直肠癌肝转移（CRLM）病变热消融后局部肿瘤进展（LTP）的影像组学模型进行独立内部及外部验证。方法从2个机构收集接受

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Investigation of the transformation of organic matter of carbonate deposits of the Semiluksky-Mendymsky horizon under hydrothermal conditions

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Petroleum 2024年第2期10卷 216-223页

作者： S.M.Petrov A.I.Lakhova e.g.Moiseeva A.g.Safiulina Institute of Petroleum Chemistry and Nanotechnologies Kazan National Research Technological University Institute of geology and Oil and gas Technologies Kazan Federal University

The paper presents the results of studies on the transformation of the organic matter of siliceous-clayey carbonate rocks of the Semiluksko-Mendymsky horizon of the Romashkino oil field in a hydrothermal fluid for an hour（with a water-to-rock ratio of 33） at 340℃ and 380℃ and pressu res of 17 and 20 *** a result of hydrothermal treatment,at 340℃ and 17 MPa,based on nitrogen porosimetry and electron microscopy data,transformations of rock-forming minerals in the rock are *** lead to an increase in the volume and average diameter of mesopores in it and the formation of micropores,as well,which improve its filtration *** the same time,the amount of kerogen in the composition of the organic matter decreases and the yield of the petroleum hydrocarbon extract increases,in which,according to the SARA analysis,the content of asphaltenes increases and the content of resins,aromatic and saturated hydrocarbons *** the composition of aroatic hydrocarbons,the proportion of a lkyltri methyl benzenes and dibenzothiophenes increases,phenanthrene homologues appear,and in the composition of saturated hydrocarbons,the amount of iso-structure alkanes decreases relative to the content of linear *** the temperature and pressure of the hydrothermal fluid to 380℃ and 20 MPa increases the degree of kerogen conversion from 12.4% to 23.6%.At the same time,changes occurring in the component composition of petroleum hydrocarbon extracts remains similar to the experiments carried out at 340℃ and 17 MPa;the content of naphthalenes decreases,the content of dibenzothiophenes increases and C11-C17,C19-C22alkyltrimethylbenzenes *** to IR spectroscopy,with increasing temperature and pressure of the hydrothermal fluid the intensity of the absorption bands of the aromatic ring,aliphatic fragments,and oxygen-containing groups increases in resins;the structural-group composition of asphaltenes changes little:aromaticity and the content of condensed

关键词： Carbonate deposits Organic matter Hydrothermal fluid Mobile hydrocarbons

Pressurized environments directly influence friction and wear of dry steel contacts—Investigations in a novel high fluid pressure tribometer

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Friction 2024年第7期12卷 1599-1617页

作者： Paul ReICHLe Jakob BARZ georg UMLAUF günter e.M.TOVAR Institute of Interfacial Process engineering and Plasma Technology(IgVP) University of StuttgartStuttgart 70569Germany Fraunhofer Institute for Interfacial engineering and Biotechnology(IgB) Stuttgart 70569Germany

To reduce the usage of classical lubricants in deep drawing,a new tribological system based on volatile lubricants was ***,a volatile medium is injected under high pressure into the interstice between drawing tool and sheet *** on temperature and pressure,the temporary lubricant may exist in its gaseous or liquid *** this study,a novel high fluid pressure tribometer was designed to investigate the friction and wear of dry steel contacts under comparable conditions like in dry deep ***,a new ball-on-disc tribometer was designed and integrated into a high-pressure *** specifically investigate the effects of different environments(technical air,liquid and gaseous carbon dioxide,nitrogen,argon)at atmospheric and high pressure(0.1 MPa,6 MPa)on tribology,the specimens and all components were operating *** the experiments,the friction was measured *** show that the highest friction occurs in air and the lowest in carbon dioxide *** to the experiments,the wear of the specimens was assessed along with changes in surface chemistry related to tribochemical ***,the tribology of the dry sliding contacts is correlated to changes of the surface *** differences as well as similarities regarding the different fluid environments are *** the results show,the differences between the media used are most pronounced at elevated ***,this work gives clear indications on the suitability of volatile lubricants in dry friction or rather gas lubrication,especially for dry deep drawing.

关键词： dry friction and dry wear gas lubrication carbon dioxide tribo-layer dry metal forming

Management of early oesophageal cancer:An overview

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World Journal of gastrointestinal Surgery 2024年第5期16卷 1255-1258页

作者： gavin g Calpin Matthew g Davey Noel e Donlon Department of Surgery Royal College of Surgeons in IrelandDublin D2Ireland Department of Upper gastrointestinal Surgery Beaumont HospitalDublin D09V2N0Ireland

The incidence of esophageal cancer,namely the adenocarcinoma subtype,continues to increase exponentially on an annual *** indolent nature of the disease renders a significant proportion inoperable at first presentation,however,with the increased utilisation of endoscopy,many early lesions are now being identified which are suitable for endotherapeutic *** article details the options available for dealing with early esophageal cancer by endoscopic mean obviating the need for surgery thereby avoiding the potential morbidity and mortality of such intervention.

关键词： esophageal cancer endotherapy endoscopic submucosal resection endoscopic mucosal resection endoscopy

Combination treatment of inflammatory bowel disease:Present status and future perspectives

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World Journal of gastroenterology 2024年第15期30卷 2068-2080页

作者： John K Triantafillidis Constantinos g Zografos Manousos M Konstadoulakis Apostolos e Papalois Inflammatory Bowel Disease Unit "Metropolitan General"HospitalHolargos 15562AtticaGreece Hellenic Society for gastrointestinal Oncology 354 Iera OdosChaidari 12461AtticaGreece The 2^(nd)Department of Surgery University of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece Unit of Surgical Research and Training The 2^(nd)Department of SurgeryUniversity of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece

The treatment of patients with inflammatory bowel disease(IBD),especially those with severe or refractory disease,represents an important challenge for the clinical *** seems to be no exaggeration to say that in these patients,not only the scientific background of the gastroenterologist is tested,but also the abundance of“gifts”that he should possess(insight,intuition,determ-ination,ability to take initiative,etc.)for the successful outcome of the *** daily clinical practice,depending on the severity of the attack,IBD is treated with one or a combination of two or more pharmaceutical *** combin-ations include not only the first-line drugs(e.g.,mesalazine,corticosteroids,antibiotics,etc)but also second-and third-line drugs(immunosuppressants and biologic agents).It is a fact that despite the significant therapeutic advances there is still a significant percentage of patients who do not satisfactorily respond to the treatment ***,a part of these patients are going to *** recent years,several small-size clinical studies,reviews,and case reports have been published combining not only biological agents with other drugs(e.g.,immunosuppressants or corticosteroids)but also the combination of two biologi-cal agents simultaneously,especially in severe *** our opinion,it is at least a strange(and largely unexplained)fact that we often use combinations of drugs in a given patient although studies comparing the simultaneous administration of two or more drugs with monotherapy are very *** mentioned above,there is a timid tendency in the literature to combine two biological agents in severe cases unresponsive to the applied treatment or patients with severe extraintestinal *** appropriate dosage,the duration of the administration,the suitable timing for checking the clinical and laboratory outcome,as well as the treatment side-effects,should be the subject of intense clinical research *** this

关键词： Biologics for immune-mediated conditions Dual-targeted treatment Combination treatment Inflammatory bowel disease Crohn’s

Malargüe Site Remediation: A Successful Solution for Uranium Mill Tailings

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原子能科学技术 2024年

作者： BARARI e DíAZ J g gIOMIA KeMPF R A National Atomic energy Commission Av.Del Libertador 8250 Ciudad Autónoma de Buenos AiresC1429BNP Argentina

Comisión Nacional de energía Atómica(CNeA) has the responsibility for restoring uranium mining facilities once the operations have finished. CNeA, within its environmental Program and in compliance with its legal responsibilities, decides to implement a restoration project for all sites related to the mining and processing of uranium ores. The Malargüe Site is located within the Province of Mendoza in the city of Malargüe. It is the first site to successfully complete its remediation. The activities consist of relocation of tailings to an engineering repository. The tailings management(encapsulation) and rehabilitation of the area was finished in June 2017. The remediation alternative for the ore tailings was selected after conducting comparative studies and submitted the project to the society for consideration. The objective of the encapsulation of the mineral tails is to isolate them from the environment, also proceeding with the decontamination and rehabilitation of the area(landscaping,post-closure monitoring and 20 years monitoring period). encapsulation consisted of the construction of a containment cell for the mine tailings, to isolate them and prevent pollutants from entering the environment through the transfer routes. To clean the impacted areas, the soil was removed, it was incorporated into the encapsulation, and the filling was carried out with natural soils from the *** prevents radon transfer to the environment, as 222Ra is an alpha emitter with a half-life of four days, which produces its own radioactive progeny. Radon progeny are solids, and when a 222Ra nucleus emits an alpha particle into the air, the resulting 218Po nucleus, momentarily electrically charged, adheres to any dust particle. Remediation prevents the discharge into the air containing radon and also containing dust particles charged with intensely radioactive radon progeny. The tasks mentioned make it possible to decrease radon emanation, reduce radiological risks to the

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Potential of Bamboo Species guadua trinii and guadua angustifolia for Nanocellulose Production

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Journal of Renewable Materials 2024年第9期12卷 1541-1555页

作者： Agatha e.R.Prado gárate Fernando e.Felissia María Cristina Area Teresa Suirezs María evangelina Vallejos Círculo de Investigación del Bambú Universidad Nacional Agraria La Molina(UNALM)Lima15026Perú Instituto de Materiales de Misiones(IMAM) Universidad Nacional de Misiones(UNaM)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Facultad de Ciencias ExactasQuímicas y Naturales(FCEQYN)Programa de Celulosa y Papel(PROCyP)Posadas3300Argentina Instituto de Materiales de Misiones(IMAM) Universidad Nacional de Misiones(UNaM)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Facultad de Ciencias Forestales(FCF)Eldorado3380Argentina

Non-traditional lignocellulosic materials are a significant resource for producing high-value products,including *** work studied the nanocellulose obtention from chemical pulps of the two fast-growing bamboo species,guadua trinii,and guadua *** pulps were produced by soda-anthraquinone(S)pulping from both autohydrolysis-pretreated(H)and unpretreated bamboo ***-pretreated(SHP)and unpretreated soda-anthraquinone(AQ)(SP)pulps were characterized by yield,Kappa number,alpha,beta,and gamma cellulose,degree of polymerization,water retention value,and *** nanocellulose was produced by a sequential chemical oxidation treatment(2,2,6,6-tetramethylpiperidine-1-oxyl,TeMPO reagent)and mechanical *** was characterized by carboxylic group content and *** results revealed that autohydrolysis pretreatment resulted in a higher hemicelluloses extraction in *** contrast,the pulping yield of unpretreated samples was higher for ***,and the soda-AQ pulps from this species exhibited better delignification than the autohydrolysis-pretreated *** crystallinity index values of the obtained pulps were high(>80%),and the alpha-cellulose contents were *** viscosities of the aqueous nanocellulose suspensions were higher for the nanocellulose solutions obtained from the unpretreated soda-AQ ***,nanocellulose from *** unpretreated soda-AQ pulps had a higher rate of carboxylic *** results of this work are significant in assessing the potential of both bamboo species as a source of high-value products within the biorefinery framework because the viscosities of the aqueous nanocellulose suspensions depend on the size and shape of *** has significant importance for industrial unit operations and potential applications.

关键词： Natural fiber guadua angustifolia guadua trinii soda-anthraquinone pulp nanocellulose

盲法和非盲法再读存在分歧的筛查乳腺钼靶:第3位阅片人对筛查结果仲裁的影响

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国际医学放射学杂志 2015年第6期 603-603页

作者： e.g.klompenhouwer A.C.Voogd g.J.den Heeten L.J.A.Strobbe V.C.Tjan-Heijnen M.J.M.Broeders 于静 Department of Radiology Catharina Hospital

摘要目的探讨额外第3位阅片人仲裁存在分歧的筛查乳腺钼靶的价值。方法本研究纳入连续性的84 927例数字化筛查乳腺钼靶,采用盲法或非盲法对钼靶进行解读。仲

关键词：乳腺钼靶盲法筛查

Paper Analytical Device for the Colourimetric Detection of Alkaline Phosphatase in Serum and Saliva

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Journal of Analysis and Testing 2024年第03期8卷 385-394页

作者： D.Alageswari A.LakshmiDevi P.e.Resmi P.V.Suneesh AarathiPradeep T.g.SatheeshBabu Department of Chemistry Amrita School of Physical Sciences Coimbatore Amrita Vishwa Vidyapeetham Amrita Biosensor Research Lab Amrita School of Engineering Coimbatore Amrita Vishwa Vidyapeetham Amrita Biomedical engineering Centre Amrita School of Engineering Coimbatore Amrita Vishwa Vidyapeetham

A paper analytical device (PAD) was developed for the colourimetric estimation of alkaline phosphatase (ALP). ALP catalyzes the hydrolysis of disodium phenyl phosphate (DSPP) to phenol, which then undergoes oxidative coupling with4-aminoantipyrine (4-AAP) producing a reddish brown-coloured quinone imine. The colourimetric reaction tested in solution has been translated onto a PAD for the point of care (PoC) testing of ALP. A uniform colour was obtained in 25 min with the introduction of ALP onto the reagent drop cast paper device. The images obtained by scanning the PAD were processed using ImageJ software. The colour intensity obtained by image processing was proportional to the concentration of ALP present in the sample. ALP in serum and saliva samples were tested using the PAD in the range of 0 to 528 U/L and0 to 187 U/L, respectively. The interference studies revealed that the PAD was selective to ALP in the presence of other biomolecules. The PAD exhibited a limit of detection (LOD) of 3.3 U/L and a sensitivity of 48.36 a.u/Log(U/L) for serum ALP and LOD of 1.69 U/L and a sensitivity of 28.5 a.u/Log (U/L) for salivary ALP. The PAD showed good agreement with the clinical methods for real samples.

关键词： Alkaline phosphatase Colourimetry ImageJ Paper analytical device Point of care testing

Challenges and opportunities in the production of magnesium parts by directed energy deposition processes

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Journal of Magnesium and Alloys 2024年第5期12卷 1663-1686页

作者： gürel Cam Ali günen Iskenderun Technical University Faculty of Engineering and Natural SciencesDepartment of Mechanical Engineering31200 Iskenderun-HatayTurkey Iskenderun Technical University Faculty of Engineering and Natural SciencesDepartment of Metallurgy and Materials Engineering31200 Iskenderun-HatayTurkey

Mg-alloys have gained considerable attention in recent years for their outstanding properties such as lightweight,high specific strength,and corrosion resistance,making them attractive for applications in medical,aerospace,automotive,and other transport ***,their widespread application is hindered by their low formability at room temperature due to limited slip *** Mg-alloys have low mechanical properties due to the presence of casting defects such as porosity and anisotropy in addition to the high *** casting methods benefit from established process optimization techniques for these problems,additive manufacturing methods are increasingly replacing casting methods in Mg alloys as they provide more precise control over the microstructure and allow specific grain orientations,potentially enabling easier optimization of anisotropy properties in certain *** metal additive manufacturing(MAM)technology also results in some manufacturing defects such as inhomogeneous microstructural evolution and porosity and additively manufactured Mg alloy parts exhibit lower properties than the wrought parts,they in general exhibit superior properties than the cast ***,MAM is a promising technique to produce Mg alloy *** energy deposition processes,particularly wire arc directed energy deposition(WA-DeD),have emerged as an advantageous additive manufacturing(AM)technique for metallic materials including magnesium alloys,offering advantages such as high deposition rates,improved material efficiency,and reduced production costs compared to subtractive ***,the inherent challenges associated with magnesium,such as its high reactivity and susceptibility to oxidation,pose unique hurdles in the application of this *** review paper delves into the progress made in the application of DeD technology to Mg-alloys,its challenges,and ***,the predominant imperfections,notably inhomo

关键词： Additive manufacturing DeD processes Arc-DeD Wire arc additive manufacturing(WAAM) 3-D printing High deposition rate

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