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主动脉夹层动脉瘤的影像学检查

德国医学 1995年第3期12卷 155-156页

作者： D.J.Beuckelmann e.erdmann 刘启功 Klinik Ⅲ für Innere Medizin Universitat zu KolnJoseph-Stelzmann-Straβe 9D-50924 KolnGermany 同济医科大学附属同济医院

急性主动脉夹层动脉瘤危及生命,及时准确的诊断和治疗对挽救生命起决定性作用。未治疗者每小时死亡率为1％,而早期治疗可明显降低病人死亡率。Stanford将主动脉夹层动脉瘤分两型:A型:夹层累及升主动脉。B型:不累及升主动脉。A型相当于De... 详细信息

急性主动脉夹层动脉瘤危及生命,及时准确的诊断和治疗对挽救生命起决定性作用。未治疗者每小时死亡率为1％,而早期治疗可明显降低病人死亡率。Stanford将主动脉夹层动脉瘤分两型:A型:夹层累及升主动脉。B型:不累及升主动脉。A型相当于DeBakeyⅠ、Ⅱ型,B型相当于Ⅲ型。手术可改善A型病人的预后,而无并发症的B型患者用药物治疗也可获得良效。

关键词：主动脉瘤超声心动图核磁共振成像 CT 血管造影

心血管学的分子生物学心功能不全和心肌肥大的表型改变

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德国医学 1994年第3期11卷 127-129页

作者： M.Bhm M.Wankerl e.erdmann 王来 Medizinisehe Klinik Ⅲ für Innere Medizin der Universitt zu Kn Josef-Stelzmann-Str.9D-50924 KlnGermany Medizinisehe Klinik Ⅲ für Innere Medizin der Universitt zu Kln Josef-Stelzmann-Str.9D-50924 KlnGermany 同济医科大学附属同济医院

各种真核细胞的表型及功能取决于其蛋白质的功能状态(离子通道、酶)、转录和翻译过程,以及基本的基因密码有无变异。每个环节的变化均可影响细胞的功能状态和结构;心功能不全及心肌肥大的进程中,上述每一环节均有相应的质与量变化,影响... 详细信息

各种真核细胞的表型及功能取决于其蛋白质的功能状态(离子通道、酶)、转录和翻译过程,以及基本的基因密码有无变异。每个环节的变化均可影响细胞的功能状态和结构;心功能不全及心肌肥大的进程中,上述每一环节均有相应的质与量变化,影响着病程发展。

关键词：心血管学分子生物学心功能不全心肌肥大

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心功能不全的抗凝治疗

德国医学 2001年第1期18卷 17-19页

作者： FDiet 吕家高华中科技大学同济医学院附属同济医院

慢性心功能不全病人血栓栓塞的危险性较高。从病理生理观点看，主要是与心腔的扩大，室壁运动障碍，收缩力减弱，心房颤动，凝血因子增加以及内皮功能损伤有关。　　虽然心功能不全病人血栓栓塞的危险性较高，但哪些病人需要抗凝治疗尚... 详细信息

慢性心功能不全病人血栓栓塞的危险性较高。从病理生理观点看，主要是与心腔的扩大，室壁运动障碍，收缩力减弱，心房颤动，凝血因子增加以及内皮功能损伤有关。　　虽然心功能不全病人血栓栓塞的危险性较高，但哪些病人需要抗凝治疗尚无一致意见。其主要原因是没有大的前瞻性的随机对照研究来验证慢性心功能不全病人口服抗凝治疗的益处。血栓栓塞的发生率　　一些小样本的回顾性的非对照研究表明慢性心功能不全病人动脉及静脉血栓栓塞发生率在1.4%～10.4%之间。较大的随访研究及大样本心功能不全研究表明血栓栓塞的总发生率在1.5～3.5/100例病人/年，其中脑栓塞的发生率最高。在V-HeFT Ⅰ和Ⅱ研究中，总的栓塞率为2.5和2.2/100例病人/年，其中中风的发生率为1.8%，外周动脉栓塞率为0.2%～0.3%，肺栓塞的发生率为0.3%。SOLVD研究中也得出类似的结果。缺血性和扩张性心肌病患者栓塞发生率没有区别。　　根据这些回顾性数据分析，在一些大型心功能不全研究中其栓塞的实际发生率既可能被低估也可能被高估。因为一方面部分死因被认为是心功能不全或心律失常所致者实际上是由动、静脉栓塞引起。另一方面这些研究的作者没有区别心源性和非心源性原因，而将所有脑血管事件却认为是心源性栓塞所致，这就过高地估计了心源性栓塞的发生率。危险组的定义　　迄今没有前瞻性的对照研究来探讨心功能不全时病人栓塞危险性的高低从而指导抗凝治疗。一些小型研究及大型心功能不全研究的回顾性分析表明栓塞危险性的高低与下列因素有关。　　性别　女性心功能不全者比男性心功能不全者血栓栓塞危险性更大。在SOLVD研究中，窦性心律的男、女心功能不全者栓塞事件发生率分别为1.8和2.4，妇女发病率高可能与肺栓塞发生率较高有关。虽然女性中风的周围动脉栓塞发生率稍高，但男女之间的这个差别无统计学意义。　　Framingham的一项研究表明，在心功能不全伴心房颤动者中，男女中风的危险度分别为1.7和2.8。　　心功能不全原因　少数研究显示，不同病因(瓣膜病、缺血性及扩张性心肌病)的心功能不全患者发生栓塞的危险性并没有差别。　　心功能不全的严重程度　只有少数研究观察了心功能不全的临床严重程度与血栓栓塞并发症之间的关系。在V-HeFT?Ⅰ和Ⅱ中，心功能不全的严重程度与栓塞的发生率呈正相关。Cioffi等的一项对406例不同程度心功能不全患者的前瞻性研究也得出了相似的结果。

关键词：心功能不全抗凝治疗血栓栓塞发生率

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心力衰竭病理生理变化的现代认识

德国医学 1994年第3期11卷 147-148页

作者： M.Bhm D.J.Beuckelmann R.H.G.Schwinger e.erdmann 王琳 Klinik Ⅲ fǜr Innere Medizin der Universitt zu Kln Germany 同济医科大学附属同济医院

各种心脏病均可致心脏泵功能下降,心输出量减少,机体为满足重要器官血液供应,一方面通过神经内分泌,另一方面靠心脏本身进行代偿。近年来对移植心脏标本的研究,对其代偿机制有进一步认识。心肌收缩力的调节 1.钙内环境:心肌收缩力与心... 详细信息

各种心脏病均可致心脏泵功能下降,心输出量减少,机体为满足重要器官血液供应,一方面通过神经内分泌,另一方面靠心脏本身进行代偿。近年来对移植心脏标本的研究,对其代偿机制有进一步认识。心肌收缩力的调节 1.钙内环境:心肌收缩力与心肌细胞内钙离子(Ca2+)浓度有关,而胞浆中 Ca2+浓度变化受细胞膜通道、肌浆网及其与蛋白质结合状况的控制。

关键词：心力衰竭病理生理学

Simplified seismic scenario analysis of existing masonry buildings accounting for local site effects

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Frontiers of Structural and Civil engineering 2024年第2期18卷 309-318页

作者： Ayşe e.ÖZSOYÖZBAY Işıl SANRI KARAPINAR Zehra N.KUTLU İsmail e.KILIÇ Department of Civil engineering Maltepe UniversityIstanbul 34857Turkey School of engineering and Construction Oryx Universal CollegeDoha 12253Qatar

This study discusses the effects of local sites and hazard amplification on the seismic vulnerability assessment of existing masonry *** this context,a rapid seismic evaluation procedure was implemented on an old masonry building stock in the historical center Galata,located inİstanbul,to determine the seismic risk priority of the built *** scenarios were generated for all soil classes,different moment magnitudes,and source-to-site distances to obtain more accurate results for the seismic vulnerability assessment of the studied building ***,damage distributions estimated under nine different scenarios with/without site effects were compared and illustrated in maps to discuss changes in vulnerability owing to amplification *** this study,by re-examining the rapid seismic evaluation procedure by including geo-hazard-based assessment,the importance of site effects on the vulnerability and risk assessment of built heritage was *** proposed framework integrating field data and local site effects is believed to advance the current applications for vulnerability assessment of masonry buildings and provide an improvement in the application of rapid seismic assessment procedures with more reliable results.

关键词： masonry buildings seismic vulnerability assessment cultural heritage local site effect

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钙拮抗剂可用以治疗心衰吗?

德国医学 1996年第2期13卷 69-69页

作者： e.erdmann 曾昭耆 Klinik Ⅲ für Innere Medizin der Univeritt Joseph-Stelzmann-Str.9D-50924 KlnGermany 北京医院

转换酶抑制剂(ACeI)用以治疗因心排出量减低的慢性左心功能衰竭患者,无疑是一大进展,迄今似仅该类药可延长患者的预期寿命。Consensus 研究称,对最重型心功能衰竭的病死率也能减低40%。对中重度慢性左心功能衰谒(NYHAⅡ-Ⅲ)在使用利尿... 详细信息

转换酶抑制剂(ACeI)用以治疗因心排出量减低的慢性左心功能衰竭患者,无疑是一大进展,迄今似仅该类药可延长患者的预期寿命。Consensus 研究称,对最重型心功能衰竭的病死率也能减低40%。对中重度慢性左心功能衰谒(NYHAⅡ-Ⅲ)在使用利尿剂、洋地黄基础上加用 ACeI。

关键词：钙拮抗剂心力衰竭药物疗法

CLASSIFICATIONS OF DUPIN HYPeRSURFACeS IN LIe SPHeRe GeOMeTRY

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Acta Mathematica Scientia 2024年第1期44卷 1-36页

作者： Thomas e.CeCIL Department of Mathematics and Computer Science College of the Holy CrossWorcesterMA01610USA

This is a survey of local and global classification results concerning Dupin hypersurfaces in S^(n)(or R^(n))that have been obtained in the context of Lie sphere *** emphasis is on results that relate Dupin hypersurfaces to isoparametric hypersurfaces in *** with these classification results,many important concepts from Lie sphere geometry,such as curvature spheres,Lie curvatures,and Legendre lifts of submanifolds of S^(n)(or R^(n)),are described in *** paper also contains several important constructions of Dupin hypersurfaces with certain special properties.

关键词： Dupin hypersurfaces isoparametric hypersurfaces Lie sphere geometry Lie sphere transformations Lie curvatures

FSCIL-eACA: Few-Shot Class-Incremental Learning Network Based on embedding Augmentation and Classifier Adaptation for Image Classification

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Chinese Journal of electronics 2024年第1期33卷 139-152页

作者： Ruru ZHANG Haihong e Meina SONG School of Computer Science Beijing University of Posts and Telecommunications education Department Information Network engineering Research Center Beijing University of Posts and Telecommunications

The ability to learn incrementally is critical to the long-term operation of AI systems. Benefiting from the power of few-shot class-incremental learning(FSCIL), deep learning models can continuously recognize new classes with only a few samples. The difficulty is that limited instances of new classes will lead to overfitting and exacerbate the catastrophic forgetting of the old classes. Most previous works alleviate the above problems by imposing strong constraints on the model structure or parameters, but ignoring embedding network transferability and classifier adaptation(CA), failing to guarantee the efficient utilization of visual features and establishing relationships between old and new classes. In this paper, we propose a simple and novel approach from two perspectives: embedding bias and classifier bias. The method learns an embedding augmented(eA) network with cross-class transfer and class-specific discriminative abilities based on self-supervised learning and modulated attention to alleviate embedding bias. Based on the adaptive incremental classifier learning scheme to realize incremental learning capability,guiding the adaptive update of prototypes and feature embeddings to alleviate classifier bias. We conduct extensive experiments on two popular natural image datasets and two medical datasets. The experiments show that our method is significantly better than the baseline and achieves state-of-the-art results.

关键词： Training Adaptation models Visualization Image recognition Prototypes Self-supervised learning Power capacitors

Investigating the impact of the universal function of the nuclear proximity potential in heavy-ion fusion cross sections

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Communications in Theoretical Physics 2024年第5期76卷 86-93页

作者： R Gharaei e Sarvari Department of Physics Sciences FacultyHakim Sabzevari UniversityPO Box 397SabzevarIran Department of Physics Faculty of ScienceFerdowsi University of MashhadPO Box 91775-1436MashhadIran Science Faculty Department of PhysicsTarbiat Modares UniversityTehranIran

The fusion barriers and cross sections of 15 colliding systems with 320≤Z_(1)Z_(2)≤1512 are investigated in detail to understand the influence of the universal function of proximity potential formalism in the heavy-ion fusion *** realize this goal,we select three versions of the phenomenological proximity potentials,including Prox.77,Zhang 2013,and Guo 2013,to calculate the nucleus-nucleus *** experimental fusion cross sections for the selected reactions are analyzed using the standard coupled-channel calculations,including couplings to the low-lying 2^(+)and 3^(-)states in the target and *** calculated results show that the universal functions of the Guo 2013 and Prox.77 models provide the lowest and highest fusion barriers,*** addition,it is found that the height of the fusion barriers is enhanced by increasing the mass number of the projectile from light to heavy *** highest sensitivity to the mass number of the projectile belongs to the results of Prox.77.A discussion is also presented on the influence of the universal function on the radial behavior of the interaction potential in the allowed region for overlapping *** results reveal that the best fit to the experimental data of the fusion cross sections for the reactions involving light and medium nuclei is obtained using the universal function of the Zhang 2013 *** the heavier systems,the results of the Guo 2013 model at sub-barrier energies provide a good description of the available data.

关键词： fusion reactions proximity-type potentials universal function coupled-channel calculations