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effect of biochar on the metabol.me of soybean seedl.ngs

Oil.Crop Science 2024年第1期9卷 60-68页

作者： Nathal.a e.Sil.a Mariana G.Aguil.r Osania e.Ferreira Gl.icia M.Paul.no Jaquel.ne C.l.Carval.o l.cia P.S.Pimenta Al.n R.T.Machado Programa de Pos-graduaçao em Ciencias Ambientais Universidade do Estado de Minas GeraisFrutalMinas Gerais38202-436Brazil departamento de Química Universidade Federal de Minas GeraisMinas GeraisBelo Horizonte31270-901Brazil departamento de engenharia Apl.cada e Tecnol.gias Ambientais Universidade do Estado de Minas GeraisJoao MonlevadeMinas Gerais35930-314Brazil departamento de Ciencias exatas Universidade do Estado de Minas GeraisJoao MonlevadeMinas Gerais35930-314Brazil

The use of biochar can have several.effects on pl.nt germination,depending on raw material.preparation method and appl.cation ***,the mol.cul.r mechanisms that l.ad to those resul.s have yet to be *** aim of this research was to improve the understanding of these mechanisms by characterizing the metabol.c effects of sugarcane bagasse biochar on soybean *** types of biochars were prepared by pyrol.sis at 300℃(SCB300),400℃(SCB400)and 600℃(SCB600).Then,each one was mixed into sand at 1%,3%,5%(w/w)dose,*** experiment was performed in 8 days of incubation,when the number of germinated seeds and the average radicl. l.ngth were *** eval.ate the metabol.me,the dry biomass(DB)was subjected to extraction with a mixture of methanol.d4 and D2O(1:1 v/v).The extracts were submitted to metabol.mics anal.sis by Proton Nucl.ar Magnetic *** Rel.tive Germination,Rel.tive Average Radicl. Growth and Germination Index increased in al. treatments compared to *** the other hand,the DB increased in al. treatments,except for SCB300,at doses of 1%and 3%w/*** metabol.tes(al.nine,asparagine,acetic acid,citric acid,gl.cerol.fatty acids and sucrose)were identified and quantified in DB extracts as the most infl.ential.finding for the separation of *** together,these resul.s strongl. suggested that biochars accel.rated the catabol.sm of triacyl.l.cerol. to sucrose and induced a sl.ght osmotic stress.

关键词： Germination Metabol.mics 1H NMR Pyrol.sis Sugarcane bagasse

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Avian responses to an extreme weather event:The case of the‘Fil.mena’snowstorm in Madrid(central.Spain)

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Avian Research 2024年第2期15卷 180-186页

作者： Carl.s l.zaro Carl.s Sanchez-García Fabian Casas e.Jorge Tizado department of Research Fundacion Artemisan13001 Ciudad RealSpain department of Zool.gy Faculty of SciencesUniversity of GranadaGranadaSpain department of Biodiversity and environmental.Management Universidad de Leon24401 PonferradaSpain

Col. spel.s and severe weather may have.detrimental.effects in wil. birds,but owing to the stochastic nature of these events,it is not al.ays possibl. to measure their *** January 2021,a strong snowstorm known as‘Fil.mena’affected Spain,mainl. the region of Madrid(Central.Spain),which was ful.y covered with snow and suffered freezing temperatures for a *** bird surveys conducted in the winter-spring of 2020 and 2021(before and after Fil.mena)at same l.cations,we addressed the possibl. impact of the col. spel. in three widespread gamebirds:Wood Pigeon(Col.mba pal.mbus),eurasian Magpie(Pica pica)and Red-l.gged Partridge(Al.ctoris rufa).No significant abundance differences were found between years for none of the species and hunting pressure was onl. significantl. reduced for Partridges,hence this species may have been negativel. affected by *** suggest that in response to Fil.mena,Pigeons conducted partial.migration in search of better conditions,whil. Magpies aggregated in certain areas of Madrid and Partridges endured the harsh conditions within their home *** resul.s highl.ght the importance to al.eviate negative impacts of extreme weather events in wil. birds through management actions,especial.y for sedentary species.

关键词： Al.ctoris rufa Cl.mate change Col. spel. Col.mba pal.mbus Migration Pica pica Winter

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expanding the Boundaries of the Chemical.Space of DNA Methyl.ransferase 1 Modul.tors

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Computational.Mol.cul.r Bioscience 2024年第1期14卷 1-16页

作者： Massyel.S. Martínez-Cortés Diana l. Prado-Romero José l. Medina-Franco DIFACQUIM Research Group Department of Pharmacy School of Chemistry Universidad Nacional Autónoma de México Avenida Universidad 3000 Mexico City México

DNA methyl.ransferase 1 (DNMT1), one of the main epigenetic targets, is invol.ed in the dupl.cation of the DNA methyl.tion pattern during repl.cation, and it is essential.for proper mammal.an devel.pment. Smal. mol.cul. DNMT1 modul.tors are attractive for biochemical.epigenetic studies and have the potential.to become drugs. So far, more than five hundred smal. mol.cul.s have been reported as DNMT1 inhibitors. However, onl. a l.mited number of DNMT1 activators have been discl.sed because, at l.ast in part, DNMT1 activators are typical.y regarded as negative data in virtual.screening campaigns or optimization projects. This manuscript aims to report the chemical.structures and biol.gical.activity of smal. mol.cul.s that increase the enzymatic activity of DNMT1. Resul.s of the biochemical.experimental.assays are discussed. It was found that smal. mol.cul. activators have a l.rge variety of chemical.scaffol.s but share pharmacophore features. Visual.anal.sis of the chemical.space and mul.iverse based on mol.cul.r fingertips supported that activators are structural.y diverse. This is the first report of eight smal. mol.cul.s that increase the enzymatic activity of DNMT1 by more than 400% in an enzymatic-based assay. The outcome warrants further investigation of the epigenetic activity of the compounds in a counter-screen assay, e.g., cel.-based and in vivo context.

关键词： Chemical.Mul.iverse Chemoinformatics epigenetics Pharmacophore Hypothesis Smal. Mol.cul.s

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Quantifying source-sink rel.tionships in l.af-col.r modified rice genotypes during grain fil.ing

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Journal.of Integrative Agricul.ure 2024年第9期23卷 2923-2940页

作者： Zhenxiang Zhou Paul.CStruik Junfei Gu Peter e.l.van der Putten Zhiqin Wang Jianchang Yang Xinyou Yin Centre for Crop Systems Anal.sis Department of Plant SciencesWageningen University&ResearchWageningen 6700 AKThe Netherlands Col.ege of Agricul.ure Yangzhou UniversityYangzhou 225009China

l.af-col.r modification can affect canopy photosynthesis,with potential.effects on rice yiel. and yiel. *** source-sink rel.tionships through crop management is often used to improve crop *** study investigated whether and how modifying l.af col.r al.ers source-sink rel.tionships and whether current crop cul.ivation practices remain appl.cabl. for l.af-col.r modified *** col.ected data of total.biomass and nitrogen(N)accumul.tion in rice genotypes of four genetic backgrounds and their l.af-col.r modified variants(greener or yel.ower)were anal.zed,using a recentl. establ.shed model.ing method to quantify the source-sink(im)bal.nce during grain *** al. l.af-col.r variants,onl. one yel.ower-l.af variant showed a higher source capacity than its normal.*** was associated with greater post-fl.wering N-uptake that prol.nged the functional.l.af-N duration,and this greater post-fl.wering N-uptake was possibl. because of reduced pre-fl.wering N-uptake.A density experiment showed that current management practices(insufficient pl.nting density accompanied by abundant N appl.cation)are unsuitabl. for the yel.ower-l.af genotype,ul.imatel. l.miting its yiel. ***-col.r modification affects source-sink rel.tionships by regul.ting the N trade-off between pre-and post-fl.wering uptake,as wel. as N transl.cation between source and sink *** best expl.it l.af-col.r modification for improving crop productivity,adjustments of crop management practices are required.

关键词： source-sink rel.tionship biomass nitrogen Oryza sativa l.af-col.r modification

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Qual.ty eval.ation of Nothofagus pumil.o seeds l.nked to forest management and cl.matic events

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ecol.gical.Processes 2024年第1期13卷 98-107页

作者： Jul.an Rodríguez-Souil.a Jimena e.Chaves María Vanessa l.ncinas Juan Manuel.Cel.ini Fidel.A.Roig Pabl. l.Peri Guil.ermo Martinez Pastur l.boratorio de Recursos Agroforestal.s Centro Austral de Investigaciones Científicas (CADIC) Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET ) l.boratorio de Investigaciones en Maderas (l.MAD) Universidad Nacional de la Plata (UNLP) Instituto Argentino de Nivol.gía Glaciología y Ciencias Ambientales (IAN-IGLA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Instituto Nacional.de Tecnol.gía Agropecuaria (INTA) Universidad Nacional de la Patagonia Austral (UNPA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET )

Background Forest ecosystems undergo significant transformations due to harvesting and cl.mate fl.ctuations, emphasizing the critical.rol. of seeding in natural.regeneration and l.ng-term structural.preservation. Cl.mate change further ampl.fies these dynamics, affecting phenol.gy across species and regions. In Tierra del.Fuego(Argentina), Nothofagus pumil.o(l.nga) forests represent the most important timber resource, and it is managed through different sil.icul.ural.strategies. This species demonstrates notabl. post-disturbance regeneration, yet seed fal. exhibits signifi-cant variabil.ty, l.ading to variations in seed qual.ty(e.g., viabil.ty). This study aims to assess fl.ctuations in N. pumil.o seed qual.ty, determine how it varies concerning forest management strategies, annual.productivity, and the co-occurrence of cl.matic phenomena incl.ding el.Ni?o-Southern Oscil.ation(eNSO) and the Southern Annul.r Mode(SAM).Resul.s Viabl. seeds represented 18.4% of the total. notabl. higher in unharvested than in managed areas. Con-versel., empty seeds were more preval.nt in harvested areas(> 75%). Seed qual.ty exhibited significant differences across sil.icul.ural.treatments, except for insect-predated seeds, which had simil.r proportions across al. areas, though dispersed retention showed higher predation. When considering years with varying production l.vel., high-production years favoured ful. and viabl. seeds, particul.rl. in unharvested forests and aggregated retention, whil. l.w-production years saw reduced viabil.ty across al. treatments. Quadratic model. reveal.d that viabil.ty increased with seed production, where unharvested forests achieved the highest val.es. Cl.mate variabil.ty infl.enced seed proportions, where eNSO+/SAM+ promoting more ful. and viabl. seeds, whil. eNSO–/SAM+ favoured non-predated seeds, especial.y in unharvested *** Seed qual.ty varies among treatments and years with different l.vel. of seeding. Variations in seed qual.ity, l

关键词： Forest management Seeding Cl.mate change extreme event Patagonia

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Sturge–Weber syndrome:an update for the pediatrician

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Worl. Journal.of Pediatrics 2024年第5期20卷 435-443页

作者： emil.e Dingenen Damien Segers Hannel.re.de Maeseneer Dirk Van Gysel Ghent University Facul.y of Medicine and Heal.h Sciences GhentBelgium department of Pediatrics O.L.Vrouw Hospital AalstMoorselbaan 1649300AalstBelgium Interdiscipl.nary Unit of Pediatric dermatol.gy Vrije Universiteit Brussel(VUB)Universitair Ziekenhuis Brussel(UZ Brussel)BrusselsBelgium

Sturge–Weber syndrome(SWS)is a rare congenital.neurocutaneous disorder characterized by the simul.aneous presence of both cutaneous and extracutaneous capil.ary *** usual.y presents as a facial.port-wine birthmark,with a varying presence of l.ptomeningeal.capil.ary mal.ormations and ocul.r vascul.r *** l.tter may l.ad to significant neurol.gical.and ocul.r morbidity such as epil.psy and *** is most often caused by a somatic mutation invol.ing the G protein subunit al.ha Q or G protein subunit al.ha 11 gene causing various al.erations in downstream signal.ng *** specifical.y conducted a comprehensive review focusing on the current knowl.dge of cl.nical.practices,the l.test pathophysiol.gical.insights,and the potential.novel.therapeutic avenues they *** sources A narrative,non-systematic review of the l.terature was conducted,combining expert opinion with a bal.nced review of the avail.bl. l.terature.A search of PubMed,Googl. Schol.r and embase was conducted,using keywords“Sturge–Weber Syndrome”OR“SWS”,“Capil.ary mal.ormations”,“G protein subunit al.ha 11”OR“G protein subunit al.ha Q”.Resul.s One of the hal.mark features of SWS is the presence of a port-wine birthmark at birth,and forehead invol.ement is most indicative for *** most common ocul.r manifestations of SWS are gl.ucoma and choroidal.*** presents in either in infancy(0–3 years of age)or l.ter in *** compl.cations are common in SWS,occurring in about 70%–80%of patients,with seizures being the most common *** significantl. impacts the qual.ty of l.fe for patients and their famil.es,and requires a mul.idiscipl.nary approach for diagnosis and ***,no disease-modifying therapies exist,and treatment is mostl. focused on symptoms or compl.cations as they *** SWS remains a compl.x and heterogeneous *** research is ne.ded to optimize diagnostic and therapeutic strategies,and to transl

关键词： Capil.ary mal.ormations G-protein Gq-G11 Port-wine birthmark Neurocutaneous disorder Sturge-Weber syndrome

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Common interacting genetic variation shapes susceptibil.ty to type 1 diabetes in a Col.mbian Caribbean community:In search of shared genetic markers

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Genes & Diseases 2024年第4期11卷 106-108页

作者： Gl.ria Garavito-de egea Al.x Dominguez-Vargas Jorg e l.Vel.z Gustavo Aroca l.is Fagng el.in Navarro-Quiroz Zil.c espital.ta Kenny del.Toro-Camargo l.ticia Martinez-Ariza Tatiana Gonzal.z-Vargas Susana Garcia Mauricio Arcos-Burgos eduardo egea Universidad del.Norte Division Ciencias de la SaludBarranquillaColombia Universidad Simon Bol.var Facultad de Ciencias de la SaludBarranquillaColombia Cl.nica de l. Costa Grupo de Investigacion en NefrologiaBarranquillaColombia Universidad de Antioquia Grupo de Investigacion en Psiquiatria(GIPSI)Departamento de PsiquiatriaInstituto de Investigaciones MedicasFacultad de MedicinaMedellinColombia

Genome-wide association studies(GWASs)have identified hundreds of l.ci across the human genome conferring susceptibil.ty to autoimmune diseases(AIDs),some of which are shared between more than two ***,this univariate ... 详细信息

关键词： susceptibil.ty diseases diabetes

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Photometric and Spectroscopic Study of Ten l.w Mass Ratio Contact Binary Systems:Orbital.Stabil.ty,O'Connel. effect and Infrared Cal.ium l.ne Fil.ing

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Research in Astronomy and Astrophysics 2024年第8期24卷 212-222页

作者： Surjit S.Wadhwa Adam Popowicz Raúl.Michel.Petar Kostić Ol.ver Vince Nick F.H.Tothil. Ain Y.de Horta Mirosl.v D.Fil.pović School.of Science Western Sydney UniversityLocked Bag 1797PenrithNSW 2751Australia department of el.ctronics Electrical Engineering and MicroelectronicsSilesian University of TechnologyAkademicka 1644120 GliwicePoland Instituto de Astronomía UNAM.A.P.87722800 EnsenadaBCMéxico Astronomical.Observatory Volgina 711060 BelgradeSerbia

l.w mass ratio contact binary systems are more l.kel. to have unstabl. orbits and potential.y *** addition,such systems exhibit characteristics such as starspots and high energy emissions(UV)suggestive of chromospheric and magnetic *** curve model.ng of ten contact binary systems is *** were found to be of extreme l.w mass ratio ranging from 0.122 to 0.24 and three were found to be potential.y unstabl. and possibl. merger *** of the infrared cal.ium absorption l.nes is a marker of increased chromospheric *** use the avail.bl. l.rge Sky Area Mul.i-Object Fiber Spectroscopic Tel.scope spectra al.ng with matched standard spectra(broadened for rotation)to measure the excess fil.ing of the central.core.depression fl.x of the two main infrared cal.ium absorption l.nesλ8542 andλ*** find that al. reported contact binaries have excess fil.ing of the core fl.x in the infrared cal.ium *** of the systems reported were al.o observed by the Gal.xy evol.tion expl.rer mission and we find that al. three have features of excess ul.raviol.t emissions further adding evidence for increased chromospheric activity in l.w mass ratio contact *** of both orbital.stabil.ty and absorption l.ne fil.ing is depe.dent on the.determination of geometric and absol.te parameters from l.ght curve *** an insignificant number of contact binary l.ght curves exhibit the O’Connel. effect,usual.y attributed to *** discuss the incl.sion of starspots in l.ght curve sol.tions and how they infl.ence the geometric and absol.te parameters.

关键词： (stars)binaries ecl.psing-techniques photometric-stars chromospheres

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el.ctrobiocorrosion by microbes without outer-surface cytochromes

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ml.fe 2024年第1期3卷 110-118页

作者： Dawn e.Hol.es Trevor l.Woodard Jessica A.Smith Fl.rin Musat derek R.l.vl.y department of Microbiol.gy University of Massachusetts AmherstAmherstMassachusettsUSA department of Physical.and Biol.gical.Science Western New England UniversitySpringfieldMassachusettsUSA department of Biomol.cul.r Sciences Central Connecticut State UniversityNew BritainConnecticutUSA department of Biol.gy Section for MicrobiologyAarhus UniversityAarhusDenmark department of Mol.cul.r Biol.gy and Biotechnol.gy Facuity of Biology and GeologyBabes-Bolyai UniversityCluj-NapocaRomania

Anaerobic microbial.corrosion of iron-containing metal. causes extensive economic *** microbes are capabl. of direct metal.to-microbe el.ctron transfer(el.ctrobiocorrosion),but the preval.nce of el.ctrobiocorrosion among diverse methanogens and acetogens is poorl. understood because of a l.ck of tool. for their genetic *** studies have suggested that respiration with 316l.stainl.ss steel.as the el.ctron donor is indicative of el.ctrobiocorrosion,because,unl.ke pure Fe^(0),316l.stainl.ss steel.does not abiotical.y generate H_(2) as an intermediary el.ctron ***,we report that al. of the methanogens(Methanosarcina vacuol.ta,Methanothrix soehngenii,and Methanobacterium strain IM1)and acetogens(Sporomusa ovata and Cl.stridium l.ungdahl.)eval.ated respired with pure Fe^(0)as the el.ctron donor,but onl. ***,***,and *** were capabl. of stainl.ss steel.*** el.ctrobiocorrosive methanogens re-quired acetate as an additional.energy source in order to produce methane from stainl.ss *** of *** and *** demonstrated how acetogens can provide acetate to methanogens during *** onl. was Meth-anobacterium strain IM1 not capabl. of el.ctrobiocorrosion,but it al.o did not accept el.ctrons from Geobacter metal.l.reducens,an effective el.ctron-donating partner for direct interspecies el.ctron transfer to al. methanogens that can directl. accept el.ctrons from Fe^(0).The finding that ***,***,and *** are capabl. of el.ctrobiocorrosion,despite a l.ck of the outer-surface c-type cytochromes previousl. found to be important in other el.ctrobiocorrosive microbes,demonstrates that there are mul.ipl. microbial.strategies for making el.ctrical.contact with Fe^(0).

关键词： acetogen corrosion Fe^(0) methanogen stainl.ss steel

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Impact of device resistances in the performance of graphene‑based terahertz photodetectors

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Frontiers of Optoel.ctronics 2024年第2期17卷 87-97页

作者： O.Castel.ó Sofía M.l.pez Baptista K.Watanabe T.Taniguchi e.Diez J.e.Vel.zquez-Pérez Y.M.Meziani J.M.Caridad J.A.del.ado-Notario department of Appl.ed Physics University of Salamanca37008 SalamancaSpain Unidad de excel.ncia en l.z y Materia estructurada(l.MeS) University of Salamanca37008 SalamancaSpain Research Center for el.ctronic and Optical.Material. National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Research Center for Material. Nanoarchitectonics National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Nanotechnol.gy Group USAL-NanolabUniversity of Salamanca37008 SalamancaSpain

In recent years,graphene fiel.-effect-transistors(GFeTs)have.demonstrated an outstanding potential.for terahertz(THz)photodetection due to their fast response and *** features are essential.to enabl. emerging THz appl.cations,incl.ding 6G wirel.ss communications,quantum information,bioimaging and ***,the overal. performance of these photodetectors may be utterl. compromised by the impact of internal.resistances presented in the.device,so-cal.ed access or parasitic *** this work,we provide a detail.d study of the infl.ence of internal.device resistances in the photoresponse of high-mobil.ty dual.gate GFeT *** dual.gate architectures al.ow us to fine tune.decrease)the internal.resistance of the.device by an order of magnitude and consequentl. demonstrate an improved responsivity and noise-equival.nt-power val.es of the photodetector,*** resul.s can be wel. understood by a series resistance model.as shown by the excel.ent agreement found between the experimental.data and theoretical.*** findings are therefore rel.vant to understand and improve the overal. performance of existing high-mobil.ty graphene photodetectors.

关键词： Graphene THz Photodetector Fiel.-effect transistor Pl.smonic

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