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Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João b.Relvas Institute of Research and Innovation in Health(i3S)and Institute for Molecular and Cell biology(IbMC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

electronic,optical,and mechanical properties of bN,AlN,and InN with zinc-blende structure under pressure

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Chinese Physics b 2017年第8期26卷 320-327页

作者： A R Degheidy e b elkenany Department of Physics Faculty of ScienceMansoura UniversityP.O.Box 35516MansouraEgypt

In this work, the electronic, optical, and mechanical properties of bN, AlN, and InN under the action of pressure are calculated. For each of these compounds, the energy band structure, band gaps（e^L_g, e~Γ_g, e^X_g）, refractive index（n）,dielectric constants（ε_∞, ε_0）, elastic constants（C_11, C_12, C_44）, and relevant parameters such as bulk（b_u）, shear（S_h）, and Young＇s（Y_0） moduli are studied, and other important parameters such as bond-stretching（α）, bond-bending（β） force constant, internal-strain parameter（ζ）, effective charges（e~＊_T, Z~＊）, anisotropy factor（I_s）, Poisson＇s ratio（P_o）, Cauchy ratio（C_a）, the ductility index（μ_D）, and linear compressibility（C0_） are also calculated. The effects of pressure on all studied properties are investigated. Our results are in good agreement with the available experimental and theoretical data for bN,AlN, and InN.

关键词： electronic properties optical properties mechanical properties bN A1N InN

Why Matter Occupies so Large a Volume?

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Communications in Theoretical Physics 2013年第12期60卷 677-686页

作者： e.b.Manoukian Institute for Fundamental Study Naresuan University

The paper represents a rigorous treatment of the underlying quantum theory, not just in words but providing the underlying technical details, as to why matter occupies so large a volume and its intimate connection with the Pauli exclusion principle, as more and more matter is put together, as well as of the contraction or shrinkage of ＂bosonic matter＂, upon collapse, for which the Panli exclusion is abolished. From the derived explicit bounds of integrals of powers of the particle number densities, explicit bounds on probabilities of the occurrences of the events just described are extracted. These probabilities lead one to infer the change of the ＂size＂ or extension of such matter, upon expansion or contraction, respectively, as their content is increased.

关键词： expansion of matter and the Pauli exclusion principle contraction or shrinkage of "bosonic mat-ter" upon collapse

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e·b·怀特随笔

Synthesis of bicyclooctane Derivatives for Kinetic Resolution

作者： (美)e·b·怀特(e.b. White)

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Chinese Chemical Letters 1997年第5期8卷 389-392页

作者： Deng, b Winterfeldt, e SHANXI UNIV DEPT CHEM TAIYUAN 030006 PEOPLES R CHINA UNIV HANNOVeR INST ORGAN CHEM D-30167 HANNOVER GERMANY

Synthesis of five 7-membered compounds containing silane, sulfur and phosphorus groups was achieved by using endo, endo-bicyclo[3.3.0]octanediol 2. These tricyclic molecules are considered as ideal substrates far kinetic resolution of the diol. A discussion of the spectral data about these compounds was given and four of them would be substrate molecules containing an sp(3) hybridized prochiral center and could be used for molecules for a kinetic resolution combining configurational diastereotopos-differentiating and diastereoisomer-differentiating reactions.

关键词： Cl Mel Synthesis of bicyclooctane Derivatives for Kinetic Resolution ppm

Tunable luminescence from Ce-doped aluminoborosilicate glasses

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Journal of Rare earths 2014年第3期32卷 217-220页

作者： e.Malchukova b.boizot Ioffe Physical Technical Institute Polytechnicheskaya St. 26 Saint-Petersburg 194021 Russia CeA IRAMIS Laboratoire des Solides Irradiés Ecole Polytechnique CNRS 91128 Palaiseau France

A series of aluminoborosilicate glasses were prepared amounts of SiO2, A1203, H3bO3, Na2CO3, and ZrO2 with adding using the melt-quenching technique for mixture of stoichiometric of different amounts of CeO〉 The samples were investigated by means of luminescence spectroscopy. Tunable luminescence from violet to blue/green was observed from these glasses with different Xe-lamp excitation wavelengths ranging from 370 to 480 nm as well as with laser excitation of 266 and 355 nm. Moreover it was found that the possibility of tuning the light by changing of excitation wavelength was not unique. The same effect was observed by adjusting conditions for luminescence measurements as well as under exposure to β-irradiation. The obtained phenomena could be explained taking into account structural characteristics of this glass and it could be concluded that tunable luminescence results from the presence of different Ce-sites the glass matrix. Thus the results suggest that Ce-doped glasses could be considered as conversion materials for blue light-emitting diode chips to generate white light-emitting diodes.

关键词： Ce-doped glass tunable emission different Re sites rare earths

Mechanical properties of Ga_xIn_(1-x)As_yP_(1-y)/GaAs system at different temperatures and pressures

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Chinese Physics b 2015年第9期24卷 313-318页

作者： A.R.Degheidy e.b.elkenany Department of Physics Faculty of ScienceMansoura University

The mechanical properties, such as the elastic constants C11, C12, C44, and bulk, Young＇s, and shear moduli, of a Ga x In1-x As y P1-y alloy lattice matching to a Ga As substrate are calculated for various As concentrations. The calculations are based on the pseudo-potential method within the virtual crystal approximation containing the effective disorder potential. The variations of the studied properties with pressure and temperature are investigated. A comparison between the calculated results and the available published data for binary parent compounds shows that they have good agreement,while the calculated results for the quaternary alloys at various temperature and pressure may be taken as a reference.

关键词： elastic constants temperature and pressure electronic band gaps

The response of temperature and hydrostatic pressure of zinc-blende Ga_xIn_(1-x)As semiconducting alloys

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Chinese Physics b 2012年第12期21卷 327-334页

作者： A.R.Degheidy e.b.elkenany Department of Physics Faculty of ScienceMansoura University

The electronic band structure of GaxIn1-xAs alloy is calculated by using the local empirical pseudo-potential method including the effective disorder potential in the virtual crystal approximation. The compositional effect of the electronic energy band structure of this alloy is studied with composition x ranging from 0 to 1. Various physical quantities such as band gaps, bowing parameters, refractive indices, and high frequency dielectric constants of the considered alloys with different Ga concentrations are calculated. The effects of both temperature and hydrostatic pressure on the calculated quantities are studied. The obtained results are found to be in good agreement with the available experimental and published data.

关键词： temperature hydrostatic pressure to GaxIn1-xAs alloys

Approximate analytical solutions and mean energies of stationary Schrodinger equation for general molecular potential

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Chinese Physics b 2021年第7期30卷 116-131页

作者： eyube e S Rawen b O Ibrahim N Department of Physics School of Physical SciencesModibbo Adama University of TechnologyP M B 2076 YolaAdamawa StateNigeria Directorate of basic and Remedial Studies Abubakar Tafawa Balewa University(ATBU)P M B 750001BauchiBauchi StateNigeria Department of Physics Faculty of ScienceP M B 1069MaiduguriBorno StateNigeria

The Schrodinger equation is solved with general molecular potential via the improved quantization *** for bound state energy eigenvalues,radial eigenfunctions,mean kinetic energy,and potential energy are obtained in compact *** modeling the centrifugal term of the effective potential,a Pekeris-like approximation scheme is ***,we use the Hellmann–Feynman theorem to derive the relation for expectation *** state energy eigenvalues,wave functions and meanenergies of Woods–Saxon potential,Morse potential,Mobius squared and Tietz–Hua oscillators are deduced from the general molecular *** addition,we use our equations to compute the bound state energy eigenvalues and expectation values for four diatomic molecules viz.H_(2),CO,HF,and O_(2).Results obtained are in perfect agreement with the data available from the literature for the potentials and *** also show that as the vibrational quantum number increases,the mean kinetic energy for the system in a Tietz–Hua potential increases slowly to a threshold value and then *** in a Morse potential,the mean kinetic energy increases linearly with vibrational quantum number increasing.

关键词： general molecular potential Schrodinger equation improved quantization rule