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Multitaper spectral method to estimate the elastic thickness of south China: Implications for intracontinental deformation

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Geoscience Frontiers 2014年第2期5卷 193-203页

作者： Yangfan Deng Zhongjie Zhang Weiming Fan Marta pérez-Gussinyé state Key Laboratory of Lithospheric evolution Institute of Geology and Geophysics Chinese Academy of Sciences Guangzhou Institute of Geochemistry Chinese Academy of Science Department of earth sciences Royal Holloway University of London

The effective elastic thickness （Te） represents the thickness of the elastic layer or the flexural rigidity of the lithosphere, the equivalent of which can be calculated from the spectral analysis of gravity and topographic data. studies of Te have profound influence on intracontinental deformation, and coupling of the tectonic blocks. In this paper, we use the multitaper spectral estimation method to calculate the coherence between Bouguer gravity and topography data, and to obtain the Te map of south China. Through the process of correction, we discuss the relationships of Te versus heat flow, and Te versus seismicity. The results show that Te distribution of south China is affected by three factors：the original age, which controls the basic feature;the Mesozoic evolution, which affects the Te distribution;and the neotectonic movement, which shaped the final distribution. The crust age has a positive correlation with the first-order Te distribution;thus the Yangtze Craton has a relatively higher Te （about 50 km） whereas the Te in Cathaysia block is only 10e20 km. By analysis and comparison among the tectonic models of south China, the Te distribution can be well explained using the flat-subduction model. As is typical with neotectonics, the region with a higher heat flow is related with a lower Te. The seismicity does not have a clear relationship with Te, but the strong seismicity could cause a low Te. seismogenic layer （Ts） has a similar trend as Te in the craton, whereas in other areas the relationship is complex.

关键词： south China effective elastic thickness spectrum estimation Heat flow seismicity

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effects of exogenous enzymes, Lactobacillus acidophilus or their combination on feed performance response and carcass characteristics of rabbits fed sugarcane bagasse

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Journal of Integrative Agriculture 2015年第3期14卷 544-549页

作者： Nahla A Abdel-Aziz Mounir el-Adawy Maria A Mariezcurrena-Berasain Abdelfattah Z M salem Jaime Olivares-pérez Ahmed e Kholif Borhami e Borhami Department of Animal and Fish production Faculty of Agriculture Alexandria University Faculty of Veterinary Medicine and Animal science Autonomous University of the State of Mexico Faculty of Veterinary Medicine and Animal science Autonomous University of Guerrero Dairy science Department National Research Centre

The aim of this study was to evaluate the effect of Lactobacillus acidophilus（LAC）, exogenous enzymes of ZAD（exogenous enzyme preparation） or their combination on feed conversion, and dressing of rabbits fed different treatments of sugarcane bagasse（sCB）. Five rations were allotted randomly to five groups of New-Zealand White（NZW） rabbits（n=10） with initial live body weight of（838±42.4） g and 5 weeks of age. Rabbits were fed on diets with different sources of fiber as follows,（i） a control diet composed of 100% berseem hay and 0% sCB,（ii） 50% berseem hay and 50% untreated sCB（UsCB）,（iii） 50% berseem hay and 50% sCB treated with L. acidophilus（LAC）,（iv） 50% berseem hay and 50% sCB treated with ZAD（ZAD）, and（v） 50% berseem hay and 50% sCB treated with a combination of LAC＋ZAD（LZ）. Treatments of sCB with L. acidophilus, ZAD and LAC＋ZAD had the highest feed conversion ratio than both UsCB and control. The dressing percentage of rabbits that fed the LAC and LZ diets was higher（p〈0.05） compared with that in the other groups. performance index（pI） for LAC group was improved（p〈0.05） compared to that for the other groups; however, pI for UsCB group was the lowest（p〈0.05）. It could be concluded that treating sCB with L. acidophilus, exogenous enzymes of ZAD or their combination improved feed conversion and performance with more positive effects with L. acidophilus than the other treatments.

关键词： exogenous enzymes feed conversion Lactobacillus acidophilus rabbit sugarcane bagasse

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Cognitive disorder and dementia in type 2 diabetes mellitus

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World Journal of Diabetes 2022年第4期13卷 319-337页

作者： Genaro G Ortiz Miguel Huerta Héctor A González-Usigli erandis D Torres-sánchez Daniela LC Delgado-Lara Fermín p pacheco-Moisés Mario A Mireles-Ramírez Blanca MG Torres-Mendoza Roxana I Moreno-Cih Irma e Velázquez-Brizuela Department of philosophical and Methodological Disciplines University Health Sciences CenterUniversity of GuadalajaraGuadalajara 44340JaliscoMexico Department of Neurology Movement Disorders ClinicSub-Specialty Medical UnitNational Western Medical CenterMexican Social Security Institute(IMSS)Guadalajara 44340JaliscoMexico University Biomedical Research Center University of ColimaColima 28040Mexico Department of Medical and Life sciences University Center of‘La Ciénega’University of GuadalajaraOcotlán 47810JaliscoMexico Department of Chemistry University Center of Exact Sciences and EngineeringUniversity of GuadalajaraGuadalajara 44340JaliscoMexico Division of Neurosciences Western Biomedical Research CenterMexican Social Security Institute(IMSS)Guadalajara 44340JaliscoMexico Gerontology postgraduate program Public Health DepartmentUniversity Health Sciences CenterUniversity of GuadalajaraGuadalajara 44340JaliscoMexico

Insulin,a key pleiotropic hormone,regulates metabolism through several signaling pathways in target tissues including skeletal muscle,liver,and *** the brain,insulin modulates learning and memory,and impaired insulin signaling is associated with metabolic dysregulation and neurodegenerative *** the receptor level,in aging and Alzheimer’s disease(AD)models,the amount of insulin receptors and their functions are *** and animal model studies suggest that memory improvements are due to changes in insulin ***,diabetes mellitus(DM)and insulin resistance are.a.sociated with age-related cognitive decline,increased levels ofβ-amyloid peptide,phosphorylation of tau protein;oxidative stress,pro-inflammatory cytokine production and dyslipidemia. Recent evidence shows that deleting brain insulin receptors leads to mildobesity and insulin resistance without influencing brain size and apoptosis ***, deleting insulin-like growth factor 1 receptor (IGF-1R) affects brain size anddevelopment, and contributes to behavior changes. Insulin is synthesized locally in the brain andis released from the neurons. Here, we reviewed proposed pathophysiological hypotheses toexplain increased risk of dementia in the presence of DM. Regardless of the exact sequence ofevents leading to neurodegeneration, there is strong evidence that mitochondrial dysfunctionplays a key role in AD and DM. A triple transgenic mouse model of AD showed mitochondrialdysfunction, oxidative stress, and loss of synaptic integrity. These alterations are comparable tothose induced in wild-type mice treated with sucrose, which is consistent with the proposal thatmitochondrial alterations are.a.sociated with DM and contribute to AD development. Alterationsin insulin/IGF-1 signaling in DM could lead to mitochondrial dysfunction and low antioxidantcapacity of the cell. Thus, insulin/IGF-1 signaling is important for increased neural processing andsystemic metabolism, a

关键词： Alzheimer´s disease Diabetes mellitus Insulin Vascular dementia Cognitive decline

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Theoretical investigation of micropolar fluid flow between two porous disks

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Journal of Central south University 2015年第7期22卷 2825-2832页

作者： p.Valipour s.e.Ghasemi M.Vatani Department of Textile and Apparel Qaemshahr Branch Islamic Azad University Young Researchers and elite Club Qaemshahr Branch Islamic Azad University Department oaf Mechanical engineering Babol University of Technology

The steady, laminar, incompressible and two dimensional micropolar flow between two porous disks was investigated using optimal homotopy asymptotic method(OHAM) and fourth order Runge–Kutta numerical method. Comparison between OHAM and numerical method shows that OHAM is an exact and high efficient method for solving these kinds of problems. The results are presented to study the velocity and rotation profiles for different physical parameters such as Reynolds number, vortex viscosity parameter, spin gradient viscosity and microinertia density parameter. As an important outcome, the magnitude of the microrotation increases with an increase in the values of injection velocity while it decreases by increasing the values of suction velocity.

关键词： theoretical investigation porous disks micropolar fluid flow optimal homotopy asymptotic method(OHAM) microrotation

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Cellular automata modelling of grain coarsening during reheating——Ⅱ. Abnormal grain growth

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Journal of University of science and Technology Beijing 2005年第1期12卷 26-32页

作者： WanhuaYu e.J.palmiere s.p.Banks JingtaoHan DepartmentofMaterialsengineering UniversityofScienceandTechnologyBeijingBeijing100083China DepartmentofengineeringMaterials UniversityofSheffieldS13JDSheffieldUK DepartmentofAutomaticControlandsystemsengineering UniversityofSheffieldS13JDSheffieldUK

The 2-dimensional cellular automata (CA) simulation technique has been utilized to investigate the abnormal grain coarsening. The growth of abnormal grains is modelled under this assumption that different grains have different boundary energies and boundary mobilities. As temperature increases, some grains may first get rid of the particle pinning effect. Thus a high probability is obtained for atoms to jump over the boundary, so that they can consume other primary retained grains quickly. From the simulation, the characteristics of the abnormal grain coarsening under different conditions are demonstrated successfully. An experiment has also been carried out to reflect the abnormal grain coarsening on the microalloy steel. simulation results are quite close to the experimental evidence.

关键词： computer simulation grain growth microstructure reheating

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physical exercises for preventing injuries among adult male football players:A systematic review

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Journal of sport and Health science 2022年第1期11卷 115-122页

作者： Jorge pérez-Gómez JoséCarmelo Adsuar pedro eAlcaraz Jorge Carlos-Vivas Health EconomyMotricity and Education(HEME)Research GroupFaculty of Sports SciencesUniversity of ExtremaduraCaceres 10003Spain UCAM Research Center for High performance sport Catholic University of MurciaMurcia 30107Spain Faculty of sport sciences Catholic University of MurciaMurcia 30107Spain

Background:Football is the most practised sport in the world and is associated with the risk of injuries in the *** studies have been published that identify injury prevention programs,but there is no review of the full body of evidence on injury prevention programs for use by football *** aim of this article was to carry out a systematic review of published studies on injury prevention programs for adult male footballers,identify points of common understanding and establish recommendations that should be considered in the design of injury prevention ***:pubMed and eMBAse databases were used to identify relevant published articles using the following keywords:"soccer"AND"injury"AND"prevention".Results:A total of 2512 studies were identified initially,but only 11 studies met the inclusion criteria,and their outcomes are *** revealed that injury prevention programs in football have focused on strength training,proprioceptive training,multicomponent programs(balance,core stability,and functional strength and mobility),and warm-up ***:Based on results from the studies analyzed,football players can lower the incidence of match and training injuries by participating in dynamic warm-up programs that include preventive exercises before games or during training sessions,and by adding strength,balance,and mobility training to the training sessions.

关键词： Balance Core stability Injury prevention programs soccer Warm-up

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Cellular automata modelling of austenite grain coarsening during reheating——I. Normal grain coarsening

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Journal of University of science and Technology Beijing 2004年第6期11卷 517-523页

作者： WanhuaYU e.J.palmiere s.p.Banks JingtaoHan Materialsscienceandengineeringschool UniversityofScienceandTechnologyBeijingBeijing100083China DepartmentofengineeringMaterials UniversityofSheffieldSheffieldS13JDUK DepartmentofAutomaticControlandsystemsengineering UniversityofSheffieldSheffieldS13JDUK

A two-dimensional cellular automaton (CA) model has been developed for thedescription of the normal grain coarsening process. The probabilistic CA method incorporatingMoore's definition of the neighbourhood is used to simulate the normal grain coarsening process witha new transition rule. The model simulates the grain coarsening process in as much detail that ispossible, from the point of initial nucleation to subsequent coarsening with computational *** unique result is that the grain coarsening speed can be controlled by the specific method, thisresult is vital to model the grain coarsening quantitatively. In order to make this model valid,experimental work has been done to provide solid evidence for this model. Comparison of themodelling result and the experimental result has been carried out.

关键词： computer simulation grain growth microstructure reheating

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Diagnosis and treatment of hepatocellular carcinoma: An update

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World Journal of Hepatology 2015年第3期7卷 362-376页

作者： Javier Tejeda-Maldonado Ignacio García-Juárez Jonathan Aguirre-Valadez Adrián González-Aguirre Mario Vilatobá-Chapa Alejandra Armengol-Alonso Francisco escobar-penagos Aldo Torre Juan Francisco sánchez-ávila Diego Luis Carrillo-pérez Department of Internal Medicine Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Department of Gastroenterology Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Department of Interventional Radiology Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Department of Transplantation Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Department of Hematology and Oncology Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

Hepatocellular carcinoma(HCC) is one of the most common malignancies leading to high mortality rates in the general population; in cirrhotic patients, it is the primary cause of death. The diagnosis is usually delayed in spite of at-risk population screening recommendations, i.e., patients infected with hepatitis B or C virus. Hepatocarcinogenesis hinges on a great number of genetic and molecular abnormalities that lead to tumor angiogenesis and foster their dissemination potential. The diagnosis is mainly based on imaging studies such as computed tomography and magnetic resonance, in which lesions present a characteristic classical pattern of early arterial enhancement followed by contrast medium "washout" in late venous phase. On occasion, when imaging studies are not conclusive, biopsy of the lesion must be performed to establish the diagnosis. The Barcelona Clinic Liver Cancer staging method is the most frequently used worldwide and recommended by the international guidelines of HCC management. Currently available treatments include tumor resection, liver transplant, sorafenib and locoregional therapies(alcoholization, radiofrequency ablation, chemoembolization). The prognosis of hepatocarcinoma is determined according to the lesion's stage and in cirrhotic patients, on residual liver function. Curative treatments, such as liver transplant, are sought in patients diagnosed in early stages; patients in more advanced stages, were not greatly benefitted by chemotherapy in terms of survival until the advent of target molecules such as sorafenib.

关键词： Hepatocellular carcinoma surveillance Liver transplant sorafenib Catheter ablation

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Impact of chitosan-based nanocarriers on cytoskeleton dynamics:Current status and challenges

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BIOCeLL 2022年第4期46卷 885-891页

作者： M.CAROLINA DI sANTO AGUsTINA ALAIMO ANA pAULA DOMÍNGUeZ RUBIO OsCAR e.pÉrez Departamento de Química Biológica Facultad de Ciencias Exactas y NaturalesUniversidad de Buenos AiresBuenos AiresArgentina Instituto de Química Biológica de la Facultad de Ciencias exactas y Naturales Consejo Nacional de Investigaciones Científicas y Técnicas(IQUIBICENCONICET)Buenos AiresArgentina

Chitosan-based nanocarriers(Cs-NCs)show a promising role in improving drugs and bioactive compounds delivery for ***,the effects exerted by Cs-NCs at the cellular level,including their recognition and uptake,have not been fully investigated *** factors,including size,shape,concentration,and surface chemistry of Cs-NCs,play an important role in determining the types of intracellular signals *** mechanism of uptake and the involvement of the cytoskeleton during the Cs-NCs endocytosis variates among the different cell types as well as further effects observed inside *** the present work,we discuss the effects induced by Cs-NCs per se on the cytoskeleton,a key component in cell architecture and *** focus of this report is made on tumoral and normal biological models in which Cs-NCs could differentially affect the cell *** recent years reports regarding the impact of Cs-NCs on cytoskeleton dynamics and the current techniques for its evaluation are summarized and *** mechanisms underlying cytoskeletal impact after cell exposure to Cs-NCs is critical for the design of safest value-added formulations in the biomedical ***,this revision points out some interesting aspects of cytoskeletal changes and cell death encompassing anti-tumoral effects.

关键词： Cytoskeletal dynamics Cellular uptake endocytosis Nanocarriers Chitosan Bioactive compounds

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Chronic pain, posttraumatic stress disorder, and opioid intake: A systematic review

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World Journal of Clinical Cases 2019年第24期7卷 4254-4269页

作者： Alicia e López-Martínez ángela Reyes-pérez elena Rocío serrano-Ibá?ez Rosa esteve Carmen Ramírez-Maestre Facultad de psicología Instituto de Investigaciones Biomédicas (IBIMA)Universidad de Málaga

BACKGROUND The literature suggests that there is a high degree of co-occurrence between chronic pain and posttraumatic stress disorder(pTsD). An association has been found between pTsD and substance abuse. pTsD is a severe disorder that should be taken into account when opioids are prescribed. It has been found that the prevalence of opioid use disorder(OUD) in chronic pain patients is higher among those with pTsD than those without this *** To perform a systematic review on the.a.sociation between pTsD, chronic noncancer pain(CNCp), and opioid intake(i.e., prescription, misuse, and abuse).MeTHODs We conducted a systematic review following the preferred Reporting Items for systematic Reviews and Meta-Analyses guidelines. The patient, Intervention,Comparator, and Outcomes(pICOs) criteria were formulated a priori in the protocol of the systematic review. A search was conducted of the pROspeRO database. In March 2019, searches were.a.so conducted of 5 other databases:pub Med, MeDLINe, psyc INFO, Web of science, and pILOTs. The scottish Intercollegiate Guidelines Network checklist for cohort studies was used to assess the selected studies for their methodological quality and risk of bias. each study was evaluated according to its internal validity, participant sampling,confounding variables, and the statistical *** A total of 151 potentially eligible studies were identified of which 17 were retained for analysis. Only 10 met the selection criteria. All the studies were published between 2008 and 2018 and were conducted in the United states. The eligible studies included a total of 1622785 unique participants. Of these, 196516 had comorbid CNCp and pTsD and were consuming opiates. The participants had a cross-study mean age of 35.2 years. The majority of participants were men(81.6%). The most common chronic pain condition was musculoskeletal pain:back pain(47.14% across studies;range: 16%-60.6%), arthritis and joint pain(31.1%;range: 18%-67.5%), and

关键词： posttraumatic stress disorder Chronic pain Opioid prescription Opioid misuse Opioid abuse

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