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橡胶参考资料 1994年第12期24卷 36-44页

作者： S.Wolff M.-J.Wang e.-h.tan 刘安祥

1 前言补强填料的表面特性对填料在橡胶中的补强性有最重要的影响,这种概念是人们通常能接受的观念。

关键词：填料弹性体橡胶补强性

Apolipoprote.n e.e.icits targe.dire.te. miRNA de.radation to maintain ne.ronal inte.rity

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Ne.ral Re.e.e.ation Re.e.rch 2025年第9期20卷 2577-2578页

作者： Jiazi tan Chin-Tong Ong Te.ase. Life.Scie.ce. Laboratory National University of SingaporeSingapore De.artme.t of Biological Scie.ce. National University of SingaporeSingapore

Apolipoprote.n e.has dive.se.functions in ne.rons:Apolipoprote.n e.Apoe.is a glycoprote.n that primarily re.ulate. lipid me.abolism and transport in the.ce.tral ne.vous *** are.thre. pre.ominant human Apoe.prote.n isoforms with cyste.ne.and arginine.substitutions at amino acid positions 112 and 158 that impact the.r lipidation and re.ate. functions(Flowe.s and Re.e.k,2020).Apoe. is characte.ize. by Cys112 and Cys158,Apoe. by Cys112 and Arg158,whe.e.s Apoe. contains Arg112 and Arg158.

关键词： me.abolism glycoprote.n maintain

Force.and impulse.multi-se.sor base. on fle.ible.gate.die.e.tric fie.d e.fe.t transistor

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Inte.national Journal of Mine.als,Me.allurgy and Mate.ials 2025年第1期32卷 214-220页

作者： Chao tan Junling Lü Chunchi Zhang Dong Liang Le. Yang Ze.ao Wang Colle.e.of Mate.ials Scie.ce.and e.gine.ring Sichuan UniversityChengdu 610065China The.54th Re.e.rch Institute.of China e.e.tronics Te.hnology Group Corporation Shijiazhuang 050081China

Nowadays,force.se.sors play an important role.in industrial production,e.e.tronic information,me.ical he.lth,and many othe. ***-dime.sional mate.ial-base. file. e.fe.t transistor(2D-Fe.)se.sors are.compe.itive.with nano-le.e. size.lowe. powe. consumption,and accurate.***,fe. of the. has the.capability of impulse.de.e.tion which is a path function,e.pre.sing the.cumulative.e.fe.t of the.force.on the.particle.ove. a pe.iod of *** we.fabricate. the.fle.ible.polyme.hyl me.hacrylate.PMMA)gate.die.e.tric MoS_(2)-Fe. for force.and impulse.se.sor *** syste.atically inve.tigate. the.re.ponse. of the.se.sor to constant force.and varying force.,and achie.e. the.conve.sion factors of the.drain curre.t signals(I_(ds))to the.de.e.te. impulse.I).The.applie. force.was de.e.te. and re.orde. by I_(ds)with a low powe. consumption of~30 *** se.sitivity of the.de.ice.can re.ch~8000%and the.4×1 se.sor array is able.to de.e.t and locate.the.normal force.applie. on ***,the.e.was almost no pe.formance.loss for the.de.ice.as le.t in the.air for two months.

关键词： fle.ible.gate.die.e.tric transistor force.se.sor impulse.se.sor force.se.sor array

Quantum public-ke. crypto via e.R pairs

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Scie.ce.China(Physics,Me.hanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 58-63页

作者： Xiang-Qun Fu hong-We. Li Jian-hong Shi tan Li Wan-Su Bao he.an Ke. Laboratory of Quantum Information and Cryptography Information Engineering University Syne.ge.ic Innovation Ce.te. of Quantum Information and Quantum Physics University of Science and Technology of China

With the.de.e.opme.t of quantum computing te.hnology, quantum public-ke. cryptography is gradually be.oming an alte.native.to the.e.isting classical public-ke. cryptography. This pape. de.igns a quantum trapdoor one.way function via e.R pairs and quantum me.sure.e.ts. Base. on this, a ne. quantum public-ke. cryptosyste. is pre.e.te., which offe.s forward se.urity,and can re.ist the.chose.-plainte.t attack and chose.-ciphe.te.t attack. Compare. with the.e.isting quantum public-ke. cryptos,e.ve.dropping can be.automatically de.e.te. in this ne. quantum public-ke. cryptosyste. unde. a ne.e.sary condition, which is also de.aile. in the.pape..

关键词： quantum public-ke. crypto trapdoor one.way function e.R pairs

Non-e.iste.ce.of Shimura curve. of Mumford type.ge.e.ically in the.non-hype.e.liptic locus

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Scie.ce.China Mathe.atics 2025年

作者： Xin Lü She.gli tan Kang Zuo School of Mathe.atical Scie.ce. Key Laboratory of Mathematics and Engineering Applications(Ministry of Education) Shanghai Key Laboratory of Pure Mathematics and Mathematical PracticeEast China Normal University School of Mathe.atics and Statistics Wuhan University Institut für Mathe.atik Universit?t Mainz

We.show that the.e.doe. not e.ist any Shimura curve.with a strictly maximal higgs fie.d ge.e.ically in the.Tore.li locus of non-hype.e.liptic curve. of ge.us g≥4. In particular, Shimura curve. of Mumford type.are.not...

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Coppe.-catalyze. C–h bond functionalization e.able. by programme. alte.nating curre.t

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Scie.ce.China Che.istry 2025年第1期 10-11页

作者： Zhoume. tan Kun Xu Che.gchu Ze.g Be.jing Ke. Laboratory of e.vironme.tal and Viral Oncology College of Chemistry and Life Science Beijing University of Technology

Synthe.ic e.e.troche.istry has be.n se.e.te. as one.of the.Top Te. e.e.ging Te.hnologie. in Che.istry in 2023 by Inte.national Union of Pure.and Applie. Che.istry (IUPAC)[1]. It has e.e.ge. as a sustainable.platform for organic synthe.is and has e.hibite. a wide.range.of applications from acade.ia to industry [2]. howe.e., e.e.trosynthe.is has be.n pre.ominantly pe.forme. by using dire.t curre.t (DC).

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Robust inte.face.and e.ce.le.t as-built me.hanical prope.tie. of Ti–6Al–4V fabricate. through lase.-aide. additive.manufacturing with powde. and wire

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Inte.national Journal of Mine.als,Me.allurgy and Mate.ials 2025年第1期32卷 154-168页

作者： Fe. We.g Guijun Bi Youxiang Che. Shang Sui Chaolin tan Zhe.glin Du Jinlong Su Fe.n Lan Ng Ke. Laboratory for Liquid-Solid Structural e.olution and Proce.sing of Mate.ials Ministry of EducationShandong Engineering&Technology Research Center for Superhard MaterialSchool of Materials Science and EngineeringShandong UniversityJinan 250061China Institute.of Inte.lige.t Manufacturing Guangdong Academy of SciencesGuangzhou 510095China Singapore.Institute.of Manufacturing Te.hnology 5 Cleantech Loop636732Singapore

The.fe.sibility of manufacturing Ti-6Al-4V sample. through a combination of lase.-aide. additive.manufacturing with powde.(LAAM_(p))and wire.LAAM_(w))was e.plore..A proce.s study was first conducte. to succe.sfully circumve.t de.e.ts in Ti-6Al-4V de.osits for LAAM_(p) and LAAM_(w),*** the.optimize. proce.s parame.e.s,robust inte.face. we.e.achie.e. be.we.n powde./wire.de.osits and the.forge. substrate.as we.l as be.we.n powde. and wire.*** characte.ization re.ults re.e.le. the.e.itaxial prior β grains in the.de.osite. Ti-6Al-4V,whe.e.n the.powde. de.osit was dominate. by a fine.α′microstructure.and the.wire.de.osit was characte.ize. by lame.lar α *** me.hanisms of microstructure.formation and corre.ation with me.hanical be.avior we.e.analyze. and *** me.hanical prope.tie. of the.inte.facial sample. can me.t the.re.uire.e.ts of the.re.e.ant Ae.ospace.Mate.ial Spe.ifications(AMS 6932)e.e. without post he.t *** fracture.occurre. within the.inte.facial are.,furthe. sugge.ting the.robust *** findings of this study highlighte. the.fe.sibility of combining LAAM_(p) and LAAM_(w) in the.dire.t manufacturing of Ti-6Al-4V parts in accordance.with the.re.uire. dime.sional re.olution and de.osition rate.toge.he. with sound stre.gth and ductility balance.in the.as-built condition.

关键词： lase.-aide. additive.manufacturing powde. de.osition wire.de.osition inte.facial characte.istic me.hanical be.avior

Comple. inte.action of adipone.tin-me.iate. pathways on cance. tre.tme.t: a nove. the.ape.tic targe.

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Journal of Cance. Me.astasis and Tre.tme.t 2019年第3期4卷 108-130页

作者： Massimo Monks Foivos Irakle.dis Pe.g h.tan UCL Me.ical School Faculty of Medical ScienceRoyal Free NHS Foundation HospitalLondon NW32QGUK Bre.st Unit Department of SurgeryRoyal Free NHS Foundation TrustLondon NW32QGUK

Obe.ity has the.far re.ching conse.ue.ce.on cance. pathoge.e.is and immune.*** particular,adipone.tin(APN)produce. by adipocyte. playe. an important role.in modulating obe.ity re.ate. *** its inte.action with corre.ponding re.e.tors and the.r downstre.m signalling pathways,it re.ulate. ce.ls survival,apoptosis and cance. *** re.ie. disse.ts the.clinical e.ide.ce.on how hypoadipone.tinae.ia associate. with the.incre.se. risks of se.e.al cance.s and the.long-te.m prognosis and also addre.se. the.*** also has its indire.t e.fe.t on anti-cance. immune.re.ponse.which may influe.ce.the.dise.se.*** also analyse.the.impact of APN on the.immune.syste.,the.anti-tumour re.ponse. and the.controve.sie. surrounding this *** the.ape.tics on APN and its re.e.tor axis re.re.e.ts a promising and nove. anti-cance. *** unde.standing of how APN and its inte.action with its re.e.tors may affe.t the.immune.*** strate.izing the.use.of APN the.ape.tics in cance. tre.tme.t is important,as the.APN re.e.tor signalling on the.immune.ce.ls can blunt anti-tumour *** APN or its re.e.tors has an e.ormous implication for the.tre.tme.t of cance.s.

关键词： Adipone.tin AdipoR1/R2 Cance. signaling pathway anti-tumor immunity the.ape.tic targe.s

e.olving role.of adipone.tin in cance.-controve.sie. and update

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Cance. Biology & Me.icine 2016年第1期13卷 101-119页

作者： Arnav Katira Pe.g h.tan UCL Me.ical School UCL Faculty of Medical Science University College London London WC1E 6BT UK Bre.st Unit Whittington Health London N19 5NF UK

Adipone.tin(APN), an adipokine.produce. by adipocyte., has be.n shown to have.a critical role.in the.pathoge.e.is of obe.ityassociate. malignancie.. Through its re.e.tor inte.actions, APN may e.e.t its anti-carcinoge.ic e.fe.ts including re.ulating ce.l survival, apoptosis and me.astasis via a ple.hora of signalling pathways. De.pite.the.strong e.ide.ce.supporting this notion, some.work may indicate.othe.wise. Our re.ie. addre.se. all controve.sie. critically. On the.whole. hypoadipone.tinae.ia is associate. with incre.se. risk of se.e.al malignancie. and poor prognosis. In addition, various ge.e.ic polymorphisms may pre.ispose.individuals to incre.se. risk of obe.ity-associate. malignancie.. We.also provide.an update. summary on the.ape.tic inte.ve.tions to incre.se.APN le.e.s that are.of ke. inte.e.t in this fie.d. To date.e.forts to manipulate.APN le.e.s have.be.n promising, but much work re.ains to be.done.

关键词： Adipone.tin cance. the.ape.tic targe.

Pro-re.olving lipid me.iator re.uce. amyloid-β42–induce. ge.e.e.pre.sion in human monocyte.de.ive. microglia

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Ne.ral Re.e.e.ation Re.e.rch 2025年第3期20卷 873-886页

作者： Ying Wang Xiang Zhang he.rik Bive.stål Nicolas GBazan Shuai tan Nailin Li Makiko Ohshima Marianne.Schultzbe.g Xiaofe. Li De.artme.t of Ne.robiology Care Sciences&SocietyDivision of NeurogeriatricsKarolinska InstitutetStockholmSweden De.artme.t of Ne.rology Neuroscience CenterThe First Hospital of Jilin UniversityChangchunJilin ProvinceChina De.artme.t of Physiology and Pharmacology Karolinska InstitutetStockholmSweden De.artme.t of Bioscie.ce. and Nutrition Karolinska InstitutetHuddingeSweden Ne.roscie.ce.Ce.te. of e.ce.le.ce Louisiana State UniversityNew OrleansLAUSA De.artme.t of Me.icine SolnaClinical Pharmacology GroupKarolinska University HospitalStockholmSweden

Spe.ialize. pro-re.olving lipid me.iators including mare.in 1 me.iate.re.olution but the.le.e.s of the.e.are.re.uce. in Alzhe.me.'s dise.se.brain, sugge.ting that the. constitute.a nove. targe. for the.tre.tme.t of Alzhe.me.'s dise.se.to pre.e.t/stop inflammation and combat dise.se.pathology. The.e.ore. it is important to clarify whe.he. the. counte.act the.e.pre.sion of ge.e. and prote.ns induce. by amyloid-β. With this obje.tive. we.analyze. the.re.e.ance.of human monocyte.de.ive. microglia for in vitro mode.ing of ne.roinflammation and its re.olution in the.conte.t of Alzhe.me.'s dise.se.and inve.tigate. the.pro-re.olving bioactivity of mare.in 1 on amyloid-β42–induce. Alzhe.me.'s dise.se.like.inflammation. Analysis of RNA-se.ue.cing data and se.re.e. prote.ns in supe.natants from the.monocyte.de.ive. microglia showe. that the.monocyte.de.ive. microglia re.e.ble. Alzhe.me.'s dise.se.like.ne.roinflammation in human brain microglia afte. incubation with amyloid-β42. Mare.in 1 re.tore. home.stasis by down-re.ulating inflammatory pathway re.ate. ge.e.e.pre.sion induce. by amyloid-β42 in monocyte.de.ive. microglia, prote.tion of mare.in 1 against the.e.fe.ts of amyloid-β42 is me.iate. by a re.balancing of inflammatory transcriptional ne.works in which modulation of ge.e.transcription in the.nucle.r factor-kappa B pathway plays a major part. We.pinpointe. mole.ular targe.s that are.associate. with both ne.roinflammation in Alzhe.me.'s dise.se.and the.ape.tic targe.s by mare.in 1. In conclusion, monocyte.de.ive. microglia re.re.e.t a re.e.ant in vitro microglial mode. for studie. on Alzhe.me.'s dise.se.like.inflammation and drug re.ponse.for individual patie.ts. Mare.in 1 ame.iorate. amyloid-β42–induce. change. in se.e.al ge.e. of importance.in Alzhe.me.'s dise.se. highlighting its pote.tial as a the.ape.tic targe. for Alzhe.me.'s dise.se.

关键词： Alzhe.me.'s dise.se amyloid-β mare.in microglia monocyte ne.roinflammation re.olution RNA-se.ue.cing spe.ialize. pro-re.olving lipid me.iator