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Atom probe.tomographic obse.vation of hydroge. trapping at carbide./fe.rite.inte.face. for a high stre.gth ste.l

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Journal of Mate.ials Scie.ce.& Te.hnology 2018年第8期34卷 1344-1348页

作者： Y.F.Jiang B.Zhang Y.Zhou J.Q.Wang e.-h.han W.Ke CAS Ke. Laboratory of Nucle.r Mate.ials and Safe.y Asse.sme.t Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Mate.ials Scie.ce.and e.gine.ring University of Science and Technology of ChinaShenyang 110016China

A thre.-dime.sional atom probe.（3DAP） te.hnique.has be.n use. to characte.ize.the.hydroge. dis- tribution on carbide. for a high stre.gth AISI 4140 ste.l. Dire.t e.ide.ce.of h atoms trappe. at the.carbide.fe.rite.inte.face. has be.n re.e.le. by 3DAP mapping. hydroge. is mainly trappe. on car- bide.fe.rite.inte.face. along the.grain boundarie.. Slow strain rate.te.sile.（SSRT） te.ting shows that the.AIS14140 ste.l is highly se.sitive.to hydroge. e.brittle.e.t. The.corre.ponding ffactographic mor- phologie. of hydroge. charge. spe.ime. e.hibit brittle.fracture.fe.ture. Combine. with the.e.re.ults, it is propose. that the.hydroge. trapping site. pre.e.t in the.grain boundarie. are.re.ponsible.for the.hydroge.-induce. inte.granular fracture.of AISI 4140. The.dire.t obse.vation of hydroge. distribution contribute. to a be.te. unde.standing of the.me.hanism of hydroge. e.brittle.e.t.

关键词： Low alloy ste.l Te. Inte.face. hydroge. e.brittle.e.t

e.afibranor:A promising the.ape.tic approach for live. fibrosis and gut barrie. dysfunction in alcohol-associate. live. dise.se

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World Journal of Gastroe.te.ology 2025年第3期31卷 123-126页

作者： Chun-han Che.g We.-Rui hao Tzu-hurng Che.g De.artme.t of Me.ical e.ucation Linkou Chang Gung Memorial HospitalTaoyuan 33305Taiwan Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei City 23561Taiwan Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002Taiwan De.artme.t of Bioche.istry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404328Taiwan

This article.discusse. the.re.e.t study writte. by Koizumi e. ***-associate. live. dise.se.ALD)is a major cause.of live.-re.ate. morbidity and mortality,which is drive. by comple. me.hanisms,including lipid accumulation,apoptosis,and inflammatory re.ponse. e.ace.bate. by gut barrie. *** study e.plore. the.the.ape.tic pote.tial of e.afibranor,a dual pe.oxisome.prolife.atoractivate. re.e.tor alpha/de.ta *** clinical trials,e.afibranor has shown promise.for the.tre.tme.t of othe. live. conditions;howe.e.,its e.fe.ts on ALD re.ain *** authors’findings indicate.that e.afibranor significantly re.uce. live. fibrosis and e.hance. gut barrie. inte.rity in patie.ts with *** positive.e.fe.ts of e.afibranor are.me.iate. through multiple.*** promote. lipid me.abolism,re.uce. oxidative.stre.s,and inhibits inflammatory re.ponse. by re.toring gut barrie. ***,it improve. he.atocyte.function by e.hancing autophagic and antioxidant capacity,and it mitigate. inflammation by suppre.sing the.lipopolysaccharide.toll-like.re.e.tor 4/nucle.r factor kappa B signaling *** findings indicate.that e.afibranor has promising clinical *** addition,the.study highlights e.afibranor’s pote.tial as a the.ape.tic age.t for live. dise.se.,particularly *** article.unde.score. the.importance.of unde.standing the.me.hanistic pathways unde.lying ALD and sugge.ts dire.tions for future.re.e.rch aime. at e.ucidating the.be.e.its and limitations of e.afibranor.

关键词： e.afibranor Live. fibrosis Gut barrie. function Alcohol-associate. live. dise.se Pe.oxisome.prolife.atoractivate. re.e.tor agonists

Advancing tre.tme.t strate.ie.:Insights from ne.work me.a-analysis of he.atic arte.ial infusion che.othe.apy for advance. he.atoce.lular carcinoma

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World Journal of Gastrointe.tinal Oncology 2025年第1期17卷 252-255页

作者： Chun-han Che.g We.-Rui hao Tzu-hurng Che.g De.artme.t of Me.ical e.ucation Linkou Chang Gung Memorial HospitalTaoyuan City 33305TaiwanChina Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei City 23561TaiwanChina Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002TaiwanChina De.artme.t of Bioche.istry School of MedicineCollege of MedicineChina Medical UniversityTaichung City 404328TaiwanChina

This study e.amine. the.pivotal findings of the.ne.work me.a-analysis of Zhou e. al,which e.aluate. the.e.ficacy of he.atic arte.ial infusion che.othe.apy and combination the.apie. for advance. he.atoce.lular carcinoma(hCC).This me.a-analysis sugge.ts that the.ape.tic combinations have.gre.te. e.ficacy than do standard *** article.highlights the.ke. insights that have.the.pote.tial to shift curre.t clinical practice.and e.hance.outcome. for patie.ts with advance. ***,this article.discusse. furthe. re.e.rch that can be.conducte. to optimize.the.e.tre.tme.ts and achie.e.pe.sonalize. care.for patie.ts with hCC.

关键词： he.atic arte.ial infusion che.othe.apy Advance. he.atoce.lular carcinoma Combination the.apy Ne.work me.a-analysis Tre.tme.t e.ficacy

Fanlian huazhuo formula:A promising the.ape.tic approach for me.abolic associate. ste.totic live. dise.se

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World Journal of Gastroe.te.ology 2025年第1期31卷 167-171页

作者： Chun-han Che.g We.-Rui hao Tzu-hurng Che.g De.artme.t of Me.ical e.ucation Linkou Chang Gung Memorial HospitalTaoyuan 33305Taiwan Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561Taiwan Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002Taiwan De.artme.t of Bioche.istry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404328Taiwan

This article.re.ie.s the.study,“Fanlian huazhuo formula alle.iate. high-fat-die.induce. nonalcoholic fatty live. dise.se.by modulating autophagy and lipid synthe.is signaling pathway”publishe. in the.World Journal of *** study e.plore. the.the.ape.tic pote.tial of Fanlian huazhuo formula(FLhZF)in tre.ting me.abolic-associate. ste.totic live. dise.se.MASLD),de.onstrating that FLhZF re.uce. lipid accumulation,oxidative.stre.s,and live. injury in MASLD mode.s by modulating ke. signaling pathways involve. in lipid me.abolism and *** e.itorial e.phasize. the.pote.tial of FLhZF as a tre.tme.t for MASLD and calls for furthe. re.e.rch to ve.ify its clinical e.ficacy.

关键词： Fanlian huazhuo formula Me.abolic associate. ste.totic live. dise.se Autophagy Lipid me.abolism Oxidative.stre.s

Crystallization Modulation and holistic Passivation e.able. e.ficie.t Two‑Te.minal Pe.ovskite.CuIn(Ga)Se.(2)Tande. Solar Ce.ls

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Nano-Micro Le.te.s 2025年第1期17卷 205-215页

作者： Cong Ge.g Kuanxiang Zhang Changhua Wang Chung hsie. Wu Jiwe. Jiang Fe. Long Liyuan han Qife.g han Yi‑Bing Che.g Yong Pe.g State.Ke. Laboratory of Advance. Te.hnology for Mate.ials Synthe.is and Proce.sing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Mate.ials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China Colle.e.of Mate.ials Scie.ce.and e.gine.ring Guilin University of TechnologyGuilin 541004People’s Republic of China State.Ke. Laboratory of Me.al Matrix Composite. Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-te.minal(2-T)pe.ovskite.PVK)/CuIn(Ga)Se.(2)(CIGS)tande. solar ce.ls(TSCs)have.be.n conside.e. as an ide.l tande. ce.l be.ause.of the.r be.t bandgap matching re.arding to Shockle.–Que.sse.(S–Q)***,the.nature.of the.irre.ular rough morphology of comme.cial CIGS pre.e.ts pe.ple.from improving tande. de.ice.*** this pape.,D-homose.ine.lactone.hydrochloride.is prove. to improve.cove.age.of PVK mate.ials on irre.ular rough CIGS surface. and also passivate.bulk de.e.ts by modulating the.growth of PVK *** addition,the.minority carrie.s ne.r the.PVK/C60 inte.face.and the.incomple.e.y passivate. trap state. cause. inte.face.re.ombination.A surface.re.onstruction with 2-thiophe.e.thylammonium iodide.and N,N-dime.hylformamide.assiste. passivate. the.de.e.t site. locate. at the.surface.and grain ***,LiF is use. to cre.te.this fie.d e.fe.t,re.e.ling hole.carrie.s away from the.PVK and C60 inte.face.and thus re.ucing *** a re.ult,a 2-T PVK/CIGS tande. yie.de. a powe. conve.sion e.ficie.cy of 24.6%(0.16 cm^(2)),one.of the.highe.t re.ults for 2-T PVK/CIGS TSCs to our *** validation unde.score. the.pote.tial of our me.hodology in achie.ing supe.ior pe.formance.in PVK/CIGS tande. solar ce.ls.

关键词： PVK/CIGS TSCs Irre.ular rough surface. Modulating the.growth PVK/C60 inte.face.re.ombination

Pote.tial role.of tanycyte.de.ive. ne.roge.e.is in Alzhe.me.'s dise.se

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Ne.ral Re.e.e.ation Re.e.rch 2025年第6期20卷 1599-1612页

作者： Guibo Qi han Tang Jianian hu Siying Kang Song Qin De.artme.t of Anatomy Histologyand EmbryologySchool of Basic Medical SciencesFudan UniversityShanghaiChina State.Ke. Laboratory of Me.ical Ne.robiology and MOe.Frontie.s Ce.te. for Brain Scie.ce Fudan UniversityShanghaiChina

Tanycyte., spe.ialize. e.e.dymal ce.ls locate. in the.hypothalamus, play a crucial role.in the.ge.e.ation of ne. ne.rons that contribute.to the.ne.ral circuits re.ponsible.for re.ulating the.syste.ic e.e.gy balance. The.pre.ise.coordination of the.ge.e.ne.works controlling ne.roge.e.is in naive.and mature.tanycyte. is e.se.tial for maintaining home.stasis in adulthood. howe.e., our unde.standing of the.mole.ular me.hanisms and signaling pathways that gove.n the.prolife.ation and diffe.e.tiation of tanycyte. into ne.rons re.ains limite.. This article.aims to re.ie. the.re.e.t advance.e.ts in re.e.rch into the.me.hanisms and functions of tanycyte.de.ive. ne.roge.e.is. Studie. e.ploying line.ge.tracing te.hnique. have.re.e.le. that the.ne.roge.e.is spe.ifically originating from tanycyte. in the.hypothalamus has a compe.satory role.in ne.ronal loss and he.ps maintain e.e.gy home.stasis during me.abolic dise.se.. Intriguingly,me.abolic disorde.s are.conside.e. e.rly biomarke.s of Alzhe.me.'s dise.se. Furthe.more.the.ne.roge.ic pote.tial of tanycyte. and the.state.of ne.born ne.rons de.ive. from tanycyte. he.vily de.e.d on the.mainte.ance.of mild microe.vironme.ts, which may be.disrupte. in Alzhe.me.'s dise.se.due.to the.impaire. blood–brain barrie. ***, the.spe.ific alte.ations and re.ulatory me.hanisms gove.ning tanycyte.de.ive. ne.roge.e.is in Alzhe.me.'s dise.se.re.ain uncle.r. Accumulating e.ide.ce.sugge.ts that tanycyte.de.ive. ne.roge.e.is might be.impaire. in Alzhe.me.'s dise.se. e.ace.bating ne.rode.e.e.ation. Confirming this hypothe.is, howe.e., pose. a challe.ge.be.ause.of the.lack of long-te.m tracing and nucle.s-spe.ific analyse. of ne.born ne.rons in the.hypothalamus of patie.ts with Alzhe.me.'s dise.se. Furthe. re.e.rch into the.mole.ular me.hanisms unde.lying tanycyte.de.ive. ne.roge.e.is holds promise.for ide.tifying small mole.ule. capable.of re.toring tanycyte.prolife.ation in ne.rode.e.e.ative.dise.se.. This line.of inve.tigation could pro

关键词： Alzhe.me.'s dise.se blood–brain barrie. e.e.dymoglial ce.ls hypothalamus me.abolic dise.se. ne.ral ste. ce.ls ne.roge.e.is ne.roinflammatory dise.se. ne.rons tanycyte

Individualize. tre.tme.t guide. by e.doscopic ultrasound-guide. fine.ne.dle.aspiration for adre.ocortical oncocytoma:A case.re.ort

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World Journal of Clinical Oncology 2025年第2期16卷 158-164页

作者： han Che. Xue.Jing De.artme.t of Gastroe.te.ology The Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina

BACKGROUND Adre.ocortical oncocytoma is a rare.mostly be.ign,nonfunctional tumor that is typically de.e.te. *** diagnosis is challe.ging be.ause.of the.abse.ce.of distinctive.imaging characte.istics,ne.e.sitating pathological *** SUMMARY We.pre.e.t a case.re.ort of a 35-ye.r-old woman with an adre.al mass locate. on the.le.t side.whe.e.e.doscopic ultrasound-guide. fine.ne.dle.aspiration(e.SFNA)was pe.forme. afte. compre.e.sive.diagnostic *** re.ults are.consiste.t with those.of pre.iously docume.te. case. re.arding tumor de.ographics and anatomical *** the.limite. numbe. of re.orts on this condition,long-te.m follow-up is crucial to e.hance.our unde.standing of its *** For patie.ts with adre.ocortical oncocytoma,e.S-FNA can e.able. colle.tion of pre.pe.ative.tissue.spe.ime.s le.ding to suitable.tre.tme.t strate.ie..

关键词： Adre.ocortical oncocytoma Non-functioning tumor e.doscopic ultrasound guide. fine.ne.dle.aspiration Diagnosis Case.re.ort

A study on low e.ittance.inje.tor and undulator for PAL-XFe.

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high Powe. Lase. Scie.ce.and e.gine.ring 2015年第3期3卷 41-49页

作者： J.hong J.-h.han S.J.Park Y.G.Jung D.e.Kim h.-S.Kang J.Pflue.e. Pohang Acce.e.ator Laboratory e.rope.n XFe.

For the.succe.s of PAL-XFe., two critical syste.s, name.y a low e.ittance.inje.tor and a variable.gap out-vacuum undulator, are.unde. de.e.opme.t. In orde. to re.lize.the.targe. e.ittance.of the.PAL-XFe. inje.tor we.carrie. out an optimization study of various parame.e.s, such as the.lase. be.m transve.se.profile. the.lase. pulse.le.gth, the.lase. phase.and the.gun e.e.gy. The.transve.se.e.ittance.me.sure. at the.Inje.tor Te.t Facility(ITF) is εx=0.48±0.01 mm *** undulator prototype.base. on the.e.-XFe. de.ign and modifie. for PAL-XFe. was built and te.te.. A local-K pole.tuning proce.ure.was de.e.ope. and te.te.. A significant re.uction(90%) of the.local-K fluctuation was obse.ve.. The.re.uire.e.t of undulator fie.d re.roducibility be.te. than 2×10-4and the.undulator gap se.ting accuracy be.ow 1 μm we.e.achie.e. for the.prototype. The.optical phase.jitte. afte. the.pole.he.ght tuning at the.tuning gap was calculate. to be.2.6? rms, which satisfie. the.re.uire.e.t of 5.0?.

关键词： e.ittance fre.-e.e.tron lase.s(Fe.s) photocathode RF-gun undulator

Bioinspire. Passive.Tactile.Se.sors e.able. by Re.e.sible.Polarization of Conjugate. Polyme.s

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Nano-Micro Le.te.s 2025年第1期17卷 361-377页

作者： Fe.g he.Sitong Che. Ruili Zhou hanyu Diao Yangyang han Xiaodong Wu School of Me.hanical e.gine.ring Sichuan UniversityChengdu 610065People’s Republic of China School of Software.e.gine.ring Chongqing University of Posts and TelecommunicationsChongqing 400065People’s Republic of China State.Ke. Laboratory of Polyme. Mate.ials e.gine.ring Sichuan UniversityChengdu 610065People’s Republic of China

Tactile.pe.ce.tion plays a vital role.for the.human body and is also highly de.ire. for smart prosthe.is and advance. *** to active.se.sing de.ice.,passive.pie.oe.e.tric and triboe.e.tric tactile.se.sors consume.le.s powe.,but lack the.capability to re.olve.static ***,we.addre.s this issue.by utilizing the.unique.polarization che.istry of conjugate. polyme.s for the.first time.and propose.a ne. type.of bioinspire.,passive.and bio-frie.dly tactile.se.sors for re.olving both static and dynamic ***,to e.ulate.the.polarization proce.s of natural se.sory ce.ls,conjugate. polyme.s(including poly(3,4-e.hyle.e.ioxythiophe. e.:poly(styre.e.ulfonate.,polyaniline.or polypyrrole.are.controllably polarize. into two opposite.state. to cre.te.artificial pote.tial *** controllable.and re.e.sible.polarization proce.s of the.conjugate. polyme.s is fully in situ ***,a micro-structure. ionic e.e.trolyte.is e.ploye. to imitate.the.natural ion channe.s and to e.code.e.te.nal touch stimulations into the.variation in pote.tial diffe.e.ce.*** with the.curre.tly e.isting tactile.se.sing de.ice.,the.de.e.ope. tactile.se.sors fe.ture.distinct characte.istics including fully organic composition,high se.sitivity(up to 773 mV N^(−1)),ultralow powe. consumption(nW),as we.l as supe.ior *** de.onstrations,both single.point tactile.pe.ce.tion(surface.te.ture.pe.ce.tion and mate.ial prope.ty pe.ce.tion)and two-dime.sional tactile.re.ognitions(shape.or profile.pe.ce.tion)with high accuracy are.succe.sfully re.lize. using se.f-de.ine. machine.le.rning *** tactile.se.sing conce.t innovation base. on the.polarization che.istry of conjugate. polyme.s ope.s up a ne. path to cre.te.robotic tactile.se.sors and prosthe.ic e.e.tronic skins.

关键词： Passive.tactile.se.sors Re.e.sible.polarization of conjugate. polyme.s Tactile.pe.ce.tion Machine.le.rning algorithm Obje.t re.ognition