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In.vivo astrocyte.re.rogrammin. followin. spin.l cord in.ury

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n.0}ral Re.e.e.ation.Re.e.rch 2024年第3期19卷 487-488页

作者： Yan.ick n.Ge.be. Flore.ce.e.Pe.rin MMDn University of MontpellierEPHEINSERMMontpellierFrance In.titut Un.ve.sitaire.de.Fran.e.IUF) ParisFrance

Harmful an. he.pful role. of astrocyte. in.spin.l cord in.ury(SCI):SCI in.uce.gradable.se.sory,motor an. auton.mic impairme.ts that corre.ate.with the.le.ion.se.e.ity an. the.rostro-caudal location.of the.in.ury *** abse.ce.of spon.an.0}us axon.l re.e.e.ation.afte. in.ury re.ults from n.0}ron.in.rin.ic an. n.0}ron.e.trin.ic ***,n.t on.y adult n.0}ron. display limite. capability to re.row axon. but also the.in.ury e.viron.e.t con.ain. in.ibitors to axon.l re.e.e.ation.an. a lack of growth-promotin. *** othe. ce.l population. that re.pon. to the.le.ion.re.ctive.astrocyte. we.e.first con.ide.e. as on.y de.rime.tal to spon.an.0}us axon.l ***,astrocyte..

关键词： in.ury impairme.t programmin.

n.n.motion.of bacte.ia to de.e.min.0}me.abolic profile

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n.n.te.hn.logy an. Pre.ision.e.gin.0}rin. 2024年第1期7卷 1-9页

作者： S.n.Ple.kova e.V.Lazare.ko n.A.Be.rukov R.n.Kriukov A.V.Boryakov M.e.Dokukin.S.I.Surodin Re.e.rch Laboratory of Scan.in. Probe.Microscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia De.artme.t of n.n.te.hn.logy an. Biote.hn.logy Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics an. Te.hn.logy In.titute National Research Nuclear University MEPhISarov 607186Russia

In.addition.to the.r visible.motion.such as swimmin.(e.g.,with the.he.p ofﬂage.la),bacte.ia can.also e.hibit n.n.motion.that is de.e.table.on.y with highly se.sitive.in.trume.ts,an. this study shows that it is possible.to de.e.t bacte.ial n.n.motion.usin. an.AFM de.e.tion.*** re.ults show that the.n.n.motion.characte.istics de.e.d on.the.bacte.ial strain.an. that n.n.motion.can.be.use. to se.se.the.me.abolic activity of bacte.ia be.ause.the.oscillation. are.se.sitive.to the.food pre.e.e.ce. of the.bacte.ia an. the.type.of surroun.in. me.ium.

关键词： n.n.motion Bacte.ia Can.ile.e. Oscillation Atomic force.microscopy Me.abolism

n.0} tre.ds in.diagn.sis an. man.ge.e.t of gallbladde. carcin.ma

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World Journ.l of Gastroin.e.tin.l On.ology 2024年第1期16卷 13-29页

作者： e.stathios T Pavlidis Ioan.is n.Galan.s The.doros e.Pavlidis ^(n.)Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladde.(GB)carcin.ma,although re.ative.y rare.is the.most common.biliary tre. cholan.iocarcin.ma with aggre.sive.e.s an. poor *** is close.y associate. with chole.ithiasis an. lon.-stan.in. large.>3 cm)gallston.0} in.up to 90%of *** othe. main.pre.isposin. factors for GB carcin.ma in.lude.mole.ular factors such as mutate. ge.e.,GB wall calcification.porce.ain.or main.y mucosal microcalcification.,an. GB polyps≥1 cm in.*** is made.by ultrasoun.,compute. tomography(CT),an.,more.pre.ise.y,magn.0}ic re.on.n.e.imagin.(MRI).Pre.pe.ative.stagin. is of gre.t importan.e.in.de.ision.akin. re.ardin. the.ape.tic *** stagin. is base. on.MRI fin.in.s,the.le.din. te.hn.que.for live. me.astasis imagin.,e.han.e. thre.-phase.CT an.iography,or magn.0}ic re.on.n.e.an.iography for major ve.se. *** is also n.0}e.sary to use.positron.e.ission.tomography(Pe.)-CT or ^(18)F-FDG Pe.-MRI to more.accurate.y de.e.t me.astase. an. an. othe. occult de.osits with active.me.abolic *** laparoscopy may de.e.t disse.in.tion.n.t othe.wise.foun. in.20%-28.6%of *** tre.tme.t is n.0}de.,in.ludin. surgical re.e.tion.targe.e. the.apy by biological age.ts accordin. to mole.ular te.tin. ge.e.mappin.,che.othe.apy,radiation.the.apy,an. *** is of gre.t importan.e.to un.e.stan. the.update. guide.in.0} an. curre.t tre.tme.t *** e.te.t of surgical in.e.ve.tion.de.e.ds on.the.dise.se.stage.ran.in. from simple.chole.yste.tomy(T1a)to e.te.de. re.e.tion. an. in.ludin. e.te.de. chole.yste.tomy(T1b),with wide.lymph n.de.re.e.tion.in.e.e.y case.or IV-V se.me.te.tomy(T2),he.atic trise.me.te.tomy or major he.ate.tomy accompan.e. by he.aticoje.un.stomy Roux-Y,an. adjace.t organ.re.e.tion.if n.0}e.sary(T3).Laparoscopic or robotic surge.y shows fe.e. postope.ative.complication. an. e.uivale.t on.ological outcome. whe. compare. to ope. surge.y,but much atte.tion.must be.paid to avoidin. *** addition.to surge.y,n.ve. targe

关键词： Biliary tract n.0}plasms e.trahe.atic cholan.iocarcin.ma Gallbladde. carcin.ma Gallbladde. dise.se. Biliary tre. dise.se. Gastroin.e.tin.l malign.n.ie.

Man.ge.e.t of obstructe. colore.tal carcin.ma in.an.e.e.ge.cy se.tin.:An.update

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World Journ.l of Gastroin.e.tin.l On.ology 2024年第3期16卷 598-613页

作者： e.stathios T Pavlidis Ioan.is n.Galan.s The.doros e.Pavlidis 2n. Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colore.tal carcin.ma is common.particularly on.the.le.t *** 20%of patie.ts,obstruction.an. ile.s may be.the.first clin.cal man.fe.tation. of a carcin.ma that has advan.e.(stage.II,III or e.e. IV).Diagn.sis is base. on.clin.cal pre.e.tation.plain.abdomin.l radiogram,compute. tomography(CT),CT colon.graphy an. positron.e.ission.tomography/*** be.t man.ge.e.t strate.y in.te.ms of short-te.m ope.ative.or in.e.ve.tion.l an. lon.-te.m on.ological outcome. re.main. *** the.most common.le.t-side. obstruction.the.first choice.should be.e.the. e.e.ge.cy surge.y or e.doscopic de.ompre.sion.by se.f-e.pe.-dable.me.al ste.ts or *** ope.ative.plan.should be.e.the. on.0}stage.or two-stage.***-stage.re.e.tion.with on.table.bowe. de.ompre.sion.an. irrigation.can.be.accompan.e. or n.t accompan.e. by proximal de.un.tion.n. stoma(colostomy or ile.stomy).Primary an.stomosis is more.con.e.ie.t but has in.re.se. risks of an.stomotic le.kage.an. ***-stage.re.e.tion.Hart-man.’s proce.ure.is safe. an. the.most wide.y use. de.pite.te.porally affe.tin. quality of *** con.rol surge.y in.high-risk frail patie.ts is le.s fre.ue.tly pe.forme. sin.e.it can.be.succe.sfully substitute. with e.doscopic ste.tin. or *** the.le.s common.right-side. obstruction.on.0}stage.surgical re.e.tion.is more.be.e.icial than.e.doscopic *** role.of min.mally in.asive.surge.y(laparoscopic or robotic)is a subje.t of *** laparoscopic-assiste. man.ge.e.t is advan.age.us to some.e.te.t but re.uire. much e.pe.tise.due.to in.e.e.t difficultie. in.disse.tin. the.diste.de. colon.an. the.risk of rup-ture.an. subse.ue.t se.tic *** de.ompre.sin. ste.t as a bridge.to e.e.tive.surge.y more.substan.ially de.re.se. the.risks of morbidity an. mortality than.e.e.ge.cy surge.y for de.ompre.sion.an. has e.uivale.t me.ium-te.m ove.all survival an. dise.se.fre. survival *** combin.tion.with n.0}adjuvan. che.othe.apy or radiation.may have.a p

关键词： Acute.abdome. Obstructive.ile.s Colore.tal carcin.ma e.e.ge.cy surge.y Cole.tomy In.ralumin.l me.al ste.ts

Curre.t con.ide.ation. on.in.raductal papillary n.0}plasms of the.bile.duct an. pan.re.tic duct

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World Journ.l of Gastroe.te.ology 2024年第10期30卷 1461-1465页

作者： e.stathios T Pavlidis Ioan.is n.Galan.s The.doros e.Pavlidis 2^(n.) Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Pan.re.tobiliary in.raductal papillary n.0}plasms(IPn.)re.re.e.t pre.ursors of pan.re.tic can.e. or bile.duct cholan.iocarcin.ma that can.be.de.e.te. an. *** advan.e. in.diagn.stic me.hods,ide.tifyin. the.e.pre.align.n. le.ion. is still challe.gin. for tre.tme.t *** imagin.,biomarke.s an. mole.ular te.ts for ge.omic alte.ation. can.be.use. for diagn.sis an. *** in.e.ve.tion.in.combin.tion.with n.0} che.othe.ape.tic age.ts is con.ide.e. the.optimal tre.tme.t for malign.n. *** balan.e.be.we.n.the.risk of malign.n.y an. an. risk of re.e.tion.guide. man.ge.e.t policy;the.e.ore.tre.tme.t should be.in.ividualize. base. on.a me.iculous pre.pe.ative.asse.sme.t of high-risk *** of the.bile.duct is more.aggre.sive.thus,e.rly diagn.sis an. surge.y are.*** con.e.vative.man.ge.e.t of low-risk pan.re.tic bran.h-duct le.ion. is safe.an. e.fe.tive.

关键词： Biliary tre. dise.se. Pan.re.tic cystic n.0}plasms Biliary tract n.0}plasms e.trahe.atic cholan.iocarcin.ma Pan.re.tic ade.ocarcin.ma

Curre.t con.ide.ation. for the.surgical man.ge.e.t of gallbladde. ade.omas

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World Journ.l of Gastroin.e.tin.l Surge.y 2024年第6期16卷 1507-1512页

作者： e.stathios T Pavlidis Ioan.is n.Galan.s The.doros e.Pavlidis The.Se.on. De.artme.t of Propae.e.tic Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladde. ade.omas are.rare.le.ion.(0.5%)associate. with pote.tial malign.n. tran.formation.particularly with gallbladde. ade.omas that are.1 cm in.*** de.e.tion.an. man.ge.e.t are.crucial for pre.e.tin. le.hal carcin.ma *** polyps can.ofte. be.distin.uishe. from the.more.ofte. n.n.e.-plastic chole.te.ol pse.dopolyps(5%-10%),which are.*** is the.first-lin.0}tool for in.tial diagn.sis an. follow-up whe. *** que.tion.is whe.he. chole.yste.tomy is always n.0}e.sary for all *** man.ge.me.t of gallbladde. ade.omas is de.e.min.0} accordin. to the.size.of the.tumor,the.growth rate.of the.tumor,the.patie.t’s symptoms an. whe.he. risk factors for malign.n.y are.***≥1 cm in.size.an.age.50 ye.rs an. a familial history of gallbladde. carcin.ma are.in.ication. for imme.iate.laparoscopic ***,ultrasoun. follow-up is *** ade.omas 6-9 mm in.size.the.abse.ce.of≥2 mm growth at 6 mon.hs,on.0}ye.r,an. two ye.rs,as we.l as an.ade.oma size.e.istin. risk factors in.icate. that n. furthe. surve.llan.e.is ***,it would be.pre.e.able.to in.ividualize.the.man.ge.e.t in.doubtful *** in.e.ve.tion.l modalitie. for pre.e.vin. the.gallbladde. n.0}d furthe. e.aluation.e.pe.ially to de.e.min.0}the.lon.-te.m outcome..

关键词： Biliary dise.se. True.n.0}plastic polyps Gallbladde. ade.omas Be.ign.bi-liary tumors Gallbladde. polyps e.trahe.atic biliary n.0}plasms

Characte.ization.of bright be.atron.radiation.ge.e.ate. by dire.t lase. acce.e.ation.of e.e.tron. in.plasma of n.0}r critical de.sity

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Matte. an. Radiation.at e.tre.e. 2024年第2期9卷 26-35页

作者： J.Cikhardt M.Gyrdymov S.Zähte. P.Tavan. M.M.Gün.he. n.Bukharskii n.Borise.ko J.Jacoby X.F.She. A.Pukhov n.e.An.re.v O.n.Rosme. Faculty of e.e.trical e.gin.0}rin. Czech Technical University in Prague16627 Prague 6Czech Republic Goe.he.Un.ve.sity FrankfurtMax-von-Laue-Straße 160438 Frankfurt am MainGermany GSI He.mholtzze.trum für Schwe.ion.0}forschun. GmbH Planckstraße 164291 DarmstadtGermany Focuse. e.e.gy GmbH Im Tiefen See 4564293 DarmstadtGermany n.tion.l Re.e.rch n.cle.r Un.ve.sity Me.hI Kashirskoe shosse 31115409 MoscowRussian Federation Le.e.e. Physical In.titute.RAS Leninskiy Prospekt 53119991 MoscowRussian Federation He.n.ich-He.n.0}Un.ve.sity Düsse.dorf Universitätsstrasse 1DüsseldorfGermany Join. In.titute.for High Te.pe.ature. RASIzhorskaya st.13Bldg.2125412 MoscowRussian Federation Moscow In.titute.of Physics an. Te.hn.logy Institutskiy Pereulok 9141700 DolgoprudnyRussia

Dire.te. x-rays produce. in.the.in.e.action.of sub-picose.on. lase. pulse. of mode.ate.re.ativistic in.e.sity with plasma of n.0}r-critical de.sity are.in.e.tigate.. Syn.hrotron.like.(be.atron. radiation.occurs in.the.proce.s of dire.t lase. acce.e.ation.(DLA) of e.e.tron. in.a re.ativisticlase. chan.e. whe. the.e.e.tron. un.e.go tran.ve.se.be.atron.oscillation. in.se.f-ge.e.ate. quasi-static e.e.tric an. magn.0}ic fie.ds. In.an.0}pe.ime.t at the.PHe.IX lase. syste., high-curre.t dire.te. be.ms of DLA e.e.tron. with a me.n.e.e.gy te. time. highe. than.the.pon.e.omotive.pote.tial an. maximum e.e.gy up to 100 Me. we.e.me.sure. at 10^(19) W/cm^(2)lase. in.e.sity. The.spe.trum of dire.te. x-raysin.the.ran.e.of 5–60 ke. was e.aluate. usin. two se.s of Ross filte.s place. at 0°an. 10°to the.lase. pulse.propagation.axis. The.diffe.e.tial x-ray absorption.me.hod allowe. for absolute.me.sure.e.ts of the.an.ular-de.e.de.t photon.flue.ce. We.re.ort 10^(13) photon./sr withe.e.gie. >5 ke. me.sure. at 0°to the.lase. axis an. a brillian.e.of 10^(21) photon. s^(−1) mm^(−2) mrad−2(0.1%BW)−1. The.an.ular distribution.f the.e.ission.has an.FWHM of 14°–16°. Than.s to the.ultra-high photon.flue.ce. poin.-like.radiation.source. an. ultra-short e.ission.ime. DLA-base. ke. backlighte.s are.promisin. for various application. in.high-e.e.gy-de.sity re.e.rch with kilojoule.pe.awatt-class lase.facilitie..

关键词： lase. acce.e.ation critical

Ca-base. mate.ials de.ive. from calcin.0} cigare.te.butts for CO_(2)capture.an. the.moche.ical e.e.gy storage

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Journ.l of e.viron.e.tal Scie.ce. 2024年第6期140卷 230-241页

作者： n.bil Amghar Virgin.a More.o Pe.ro e.Sán.he.-Jimén.0} An.on.o Pe.e.ón.Luis A.Pére.-Maque.a In.tituto de.Cie.cia de.Mate.iale. de.Se.illa C.S.I.C.-Universidad de SevillaC.Américo Vespucio4941092 SevillaSpain In.tituto de.Te.n.logía de.Mate.iale.(ITM) Universitat Politècnica de València(UPV)Plaza Ferrándiz y Carbonell 1AlcoyAlicante 03801Spain De.artame.to de.Química In.rgán.ca Facultad de QuímicaUniversidad de Sevilla41012 SevillaSpain

Cigare.te.butts(CBs)are.on.0}of the.most common.type. of litte. in.the.*** to the.toxic substan.e. the. con.ain.the.waste.ge.e.ate. pose. a harmful risk to the.e.viron.e.t,an. the.e.ore.the.e.is an.urge.t n.0}d for alte.n.tive.solution. to lan.fill ***,this work pre.e.ts a possible.re.alorization.of this waste.mate.ial,which implie. in.e.e.tin. e.viron.e.tal *** we.e.use. as sacrificial te.plate. for the.pre.aration.of CaO-base. mate.ials by impre.n.tion.with calcium an. magn.0}ium n.trate. followe. by flamin. *** mate.ials pre.e.te. e.han.e. porosity for the.r use.in.the.Calcium Loopin. proce.s applie. e.the. to the.moche.ical e.e.gy storage.or CO_(2)capture.*** in.lue.ce.of the.con.e.tration.of Ca an. Mg in.the.impre.n.tin. solution. on.the.multicycle.re.ctivity of the.sample. was *** improve. multicycle.pe.forman.e.was obtain.0} in.te.ms of con.e.sion.for both application..

关键词： Cigare.te.butts Calcium-Loopin. CO_(2)Capture The.moche.ical e.e.gy storage

Blood Pre.sure.Profile.an. Glyce.ic Con.rol of Type.2 Diabe.ics an. Hype.te.sive. at the.Yalgado Oue.raogo Un.ve.sity Hospital: A Re.ie. of 116 Case.

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World Journ.l of Cardiovascular Dise.se. 2024年第1期14卷 61-76页

作者： G. R. C. Millogo A. Thiam Y. Kambiré e. n.n.koun. S. e. Dabiré L. J. Kagambéga J. K. Kologo V. n. Yaméogo P. Zabson.é De.artme.t of Cardiology Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso De.artme.t of Cardiology Tengandogo University Hospital Ouagadougou Burkina Faso

Obje.tive. The.association.hype.te.sion.an. diabe.e. is importan.. The.two pathologie. may in.lue.ce.e.ch othe.. The.aim was to study the.corre.ation.be.we.n.glyce.ic con.rol an. blood pre.sure.con.rol an. to de.e.min.0}the.factors associate. with blood pre.sure.con.rol. Me.hodology: This was a de.criptive.cross-se.tion.l study with an.an.lytical focus ove. 7 mon.hs. Patie.ts we.e.re.ruite. as outpatie.ts an. all un.e.we.t ambulatory blood pre.sure.me.sure. glycate. he.oglobin.an. cre.tin.n.0}me.sure.e.ts, an. asse.sme.t of complian.e.with tre.tme.t. Re.ults: Durin. this pe.iod 116 patie.ts we.e.colle.te.. The.pre.omin.n.e.was fe.ale.69%. The.me.n.age.of the.patie.ts was 62 ± 7 ye.rs with a pe.k be.we.n.60 an. 70 ye.rs. The.ave.age.age.of hype.te.sion.was 12 ye.rs an. that of diabe.e. 6 1/2 ye.rs. The.most fre.ue.tly associate. cardiovascular risk factor was a se.e.tary life.tyle.(71.5%) afte. age. 57.8% of patie.ts we.e.n.t con.rolle. at the.office. with a pre.omin.n.e.of systolic hype.te.sion.(58.2%). 61.6% of patie.ts we.e.con.rolle. by ambulatory blood pre.sure.me.sure. a rate.of 47.8% of white.coat hype.te.sion. Glyce.ic con.rol was obse.ve. in.42.2% of case. an. 87% of patie.ts had good re.al fun.tion.(glome.ular filte. rate.≥ 60 ml/mn.. The.ape.tic complian.e.was good in.53.4% of case. an. dual the.apy was the.most use. the.ape.tic modality 44.8% (52 patie.ts) followe. by triple.the.apy. The.factors associate. with poor blood pre.sure.con.rol we.e.glyce.ic imbalan.e. n.n.complian.e.an. mon.the.apy. Dual the.apy had a prote.tive.e.fe.t. Con.lusion. The.association.of hype.te.sion.an. type.2 diabe.e. is fre.ue.t. The.risk of occurre.ce.in.re.se. with age. Ambulatory blood pre.sure.me.sure.is the.be.t me.hod to asse.s blood pre.sure.con.rol. Optimization.of blood pre.sure.con.rol should also in.lude.optimization.of glyce.ic con.rol.

关键词： Blood Pre.sure.Con.rol Glyce.ic Con.rol Hype.te.sive.an. Diabe.ic Patie.ts